The face is the calling card of any person. Various skin problems can spoil the appearance and reduce self-esteem: acne, age spots, acne. Azelaic acid can be used to treat rashes. It is often used in cosmetic formulations. The substance has a positive effect on the skin and helps to improve the condition of the epidermis.

What is a substance?

Nonandioic acid (its other name is azelaic) belongs to the category of dermatotropic agents and has properties inherent in all carboxylic acids. The substance is in the form of a white crystalline powder, which is insoluble in water at room temperature. The crystals can only be dissolved in boiling water or ethyl alcohol.

In the production of cosmetics, azelaic acid is used due to the presence of antiseptic and disinfectant properties. The water-soluble derivative of this component is often added to preparations that can lighten the skin and eliminate age spots. Acid can have a detrimental effect on staphylococci and propionibacteria, which cause acne. The substance regulates the work of the sebaceous glands and penetrates deep into the skin. Even with prolonged use of products based on this organic substance, it will not be addictive.

Properties

Due to the presence of the same chemical and physical properties as those of carboxylic acids, azelaic acid is able to penetrate to the deepest layers of the epidermis, while eliminating pathogenic microorganisms that cause various inflammatory processes. After entering the body, the organic matter is transformed into dibasic carboxylic acids, which are better absorbed.

Nonandioic acid has become widespread in the field of cosmetology, not only due to its pronounced antimicrobial effect. The substance also has the following properties:

• able to eliminate pigmentation and even out the color of the skin;
• saturates the epidermis with oxygen;
• slows down the growth of keratinocytes, which prevents the upper layer of the skin from thickening;
• improves the work of skin pores, due to which dirt does not accumulate in them, comedones do not form;
• increases the elasticity of the skin;
• effectively copes with the symptoms of rosacea;
• eliminates post-acne and tightens pores.

In what cases should it be used?

The positive effect of azelaic acid on the skin of the face is undeniable. Due to its antimicrobial properties, it is often recommended for use in the treatment of acne and comedones.

For oily skin, this organic compound is a real lifesaver. With its help, it is possible to significantly reduce the production of sebum and eliminate oily sheen. Indications for the use of products based on azelaic acid are skin diseases such as seborrhea, dermatitis, demodicosis, rosacea.

Peeling

Peeling helps to remove the keratinized layer of the epidermis and improve the condition of the skin. The procedure is usually carried out using special means that are of chemical origin. Azelaic acid is one of these organic compounds. After being applied to the epidermis, it begins to have a detrimental effect on the bacteria that cause inflammation, and prevents the occurrence of new rashes. Acid successfully copes with acne in the mild and moderate stages of the course.

Peeling with this component has a minimum of contraindications, is suitable for the most sensitive skin and rarely causes side effects. It is recommended to resort to such a procedure before deep cleaning of the skin, laser resurfacing and microdermabrasion.

Usually, azelaic acid is used for peeling in combination with other components. It goes well with lactic, salicylic, mandelic, glycolic acid, extracts of medicinal plants.

How does peeling work?

Effective facial cleansing can be done using azelaic acid. The effect on the skin in this case will be antibacterial, anti-inflammatory, whitening, and vascular strengthening. In addition, the active substance has antioxidant properties and is able to remove toxic substances from the skin.

A mild effect on the epidermis avoids the occurrence of peeling and redness after the procedure. With regular peeling, the substance will accumulate in the skin, and prevent the appearance of acne and other inflammatory processes.

Azelaic acid preparations

You can buy nonanedioic acid in its pure form. It is usually sold in pharmacies without a prescription. Fine powder is used for the preparation of home cosmetics. However, experts still recommend using this substance as part of ready-made creams, gels and ointments. Such cosmetics will have a complex effect on the epidermis and will help you get rid of dermatological problems faster.

When choosing a product, it is necessary to pay attention to the concentration of the active ingredient. It is on this that the effectiveness of the drug will depend. A concentration of 20% is considered safe and effective. In the composition of ointments and gels, the organic substance is usually found in combination with other active ingredients.

Azelaic acid products include:

1. AkneStop.
2. "Azogel".
3. Skinoren.
4. "Azelex".
5. "Aziks-Derm".
6. "Azelik".

These are the most popular remedies that are used to treat various skin diseases.

"AcneStop": description of the product

To cleanse the skin of comedones and acne, a huge number of special preparations are currently being produced. The Ukrainian pharmaceutical manufacturer Arterium offers an effective remedy based on azelaic acid called AcneStop. As excipients, the composition uses benzoic acid, propylene glycol, glycerin, octyldodecanol and macrogol stearate.

The drug is produced in the form of a cream, packaged in tubes of 30 g. The concentration of the active ingredient is 20% (1 g of cream contains 0.2 g of acid).

The drug "AkneStop" is intended for external use only. With its help, it is possible to successfully fight bacteria that cause inflammation in the layers of the epidermis. The drug reduces the production of free radicals that support inflammation, inhibits the growth of abnormal melanocytes that cause pigmentation of the skin.

Features of use

The AkneStop cream is used in the treatment of acne, pigmentation, comedones. The manufacturer recommends applying the product to problem areas of the dermis twice a day. The course of therapy usually lasts 6-8 weeks. In certain cases, treatment is extended up to 6 months.

Before applying the cream / ointment with azelaic acid, you must first clean the skin and use a lotion or foam. The skin should be completely dry and only after that you need to start applying the cream, which is rubbed with light movements.

The drug may not have the desired therapeutic effect if it is not used on a regular basis. The results of therapy should be evaluated after 2-3 weeks. Cream "AcneStop" can be combined with other methods of treating acne and pimples.

How effective is Skinoren?

Problematic skin causes a lot of discomfort and psychological discomfort. To eliminate rashes and inflammation on the epidermis, many dermatologists recommend using Skinoren. It is available in cream and gel form. The active ingredient is azelaic acid. As part of the cream, its concentration is 20%, and in the gel - 15%. The cream has a dense texture and is a homogeneous mass of white color. Packaged in tubes of 30 g. The gel is lighter, opaque. It goes on sale in tubes of 5, 15 and 30 g.

After using the drug "Skinoren" with azelaic acid for acne, there is a significant improvement in the condition of the skin. The active substance regulates the work of the sebaceous glands, relieves inflammation, and normalizes keratinization processes. The drug has a low degree of absorption and, after application to the epidermis, practically does not penetrate into the systemic circulation.

Indications

Most often, "Skinoren" is used to treat teenage acne. In the transitional age, the formation of sebum is significantly increased, which leads to clogging of pores and further inflammation. The cream helps to change the composition of sebum, making it more liquid. In this form, it does not interfere with the pores to “breathe”.

The external agent does not cause systemic side effects. Occasionally, cases of local allergic reactions in the form of itching, redness or burning are recorded. With acne, after applying "Skinoren", peeling of the dermis may occur, symptoms of contact dermatitis, erythema appear.

The regimen for the use of the drug is selected only on an individual basis. The gel or cream must be applied in a thin layer on the inflamed skin. The procedure is repeated no more than twice a day. After handling, wash your hands thoroughly. If irritation occurs during the use of the product, it is worth reducing the dosage and reducing the frequency of use of the external agent.

Azelaic acid is a white crystalline substance that often becomes one of the ingredients of cosmetics designed to solve a wide range of dermatological and some aesthetic skin problems. After using the cream with azelaic acid, the general condition of the skin improves. Sometimes the result after a long time of use is similar to the effect after salon cosmetic procedures.

Let's try to study the main properties of azelaic acid, the features of its effect on the skin, and also determine who needs to use the cream, which contains it.

For what problems is azelaic acid cream relevant?

You should pay attention to cosmetics with azelaic acid if you are familiar with the following problems:

• violation of the processes of sebum secretion;
• hyperpigmentation;
• acne, acne, comedones and other types of skin rashes;
• wrinkles and flaccid ptotic skin;
• seborrhea;
• post-acne, the consequences of burns and scars;
• pallor, unhealthy complexion;
• frequent occurrence of oily sheen;
• blockage of the sebaceous ducts.

Properties of creams with azelaic acid

Azelaic acid can be found on the list of cosmetic ingredients for oily skin types, but it is also sometimes added to products for skin prone to dryness. In addition, this substance is an indispensable component in the treatment of acne and acne. At the same time, researchers periodically reveal new beneficial properties of azelaic acid, which allows us to talk about its multifunctionality. Properties:

Brightening effect	Elimination of pigmentation, spots, redness on the skin.
Antibacterial effect	Azelaic acid is a fairly common ingredient in skin cleansers.
Anti-inflammatory action	Treatment of certain dermatological diseases accompanied by inflammatory processes.
Smoothing effect	Achieved with long-term and regular use. Azelaic acid will not help solve the problem of deep mimic wrinkles, but it will make them less pronounced and prevent the formation of new age-related changes.
Antiseborrheic effect	Azelaic acid has long been used in the treatment of seborrhea.

Face cream with azelaic acid will be useful at any age. But most often it is used by teenagers when the skin is prone to acne. The active substances of azelaic acid are able to penetrate into the deep layers of the skin and into its cells, effectively fight against various pathogenic microorganisms that provoke inflammation and acne, and help regulate the natural processes of sebum formation.

The smoothing of wrinkles, which aging skin needs, is provided by saturating the cells with oxygen and the ability of azelaic acid to stimulate renewal processes.

What popular creams contain azelaic acid?

When getting acquainted with azelaic acid, you should be careful, because for hypersensitive skin or in the presence of an individual allergic reaction, products based on it are contraindicated. If you have dermatological problems, it is recommended to consult a specialist before using a cream with antibacterial properties, which includes azelaic acid.

Here are some examples of popular remedies that may be recommended for the treatment of certain dermatological diseases, acne and other rashes, to improve the general condition and color of the skin, to combat inflammation, age-related changes and wrinkles. Please note that these cosmetic and dermatological products contain other components in addition to azelaic acid, so properties may vary.

• "Azogel"- a cream that can be used not only for the treatment of acne that has already appeared, but also for the prevention of many dermatological diseases. This tool fights pigmentation, inflammation, black spots, and also slows down the formation of fatty acids (about 130 rubles);
• Gel "Azelik"- a remedy with azelaic and benzoic acids, as well as other active substances, the action of which is aimed at protecting the skin from factors that affect the occurrence of acne (approx. 400 rubles);

• "Skinoren"- a popular cream, which includes not only azelaic, but also benzoic acid. With it, you can cure even the most persistent acne that does not go away for a long period of time (approx. 500 rubles);
• "Arcadia"- cream with azelaic acid against acne and other skin imperfections, which has fast-acting antibacterial and softening properties. Means "Arcadia" can be attributed to therapeutic creams based on azelaic acid (about 1000 rubles);
• Gigi Bioplasma - This is a face cream that prevents acne, fights post-acne and blemishes on the skin, and also smoothes wrinkles and promotes healing of damaged skin (approx. 2400 rubles).

Azelic (azelaic acid) gel for external use 15%

Indications for use: Acne (acnevulgaris), rosacea.

I was prescribed an azelaic acid preparation by a cosmetologist when I visited him before the previous facial cleansing. Since it was summer then, she explained that azelaic acid for the face can just be used during the period of active sun, and prescribed to smear the face with a thin layer of the product twice a day, in the morning and in the evening.

To be honest, I was prescribed skinoren, but from the reviews here I learned that there is azelic, an analogue of skinoren - they have one active ingredient, but the latter wins significantly in price.

°▪○*Compare February 2017 prices per tube 30 g. 15% of the drug:

Azelik gel price from 522 to 827 rubles.

Skinoren: 840 - 1373 rubles.

Conclusion: azelic gel is an analogue, cheaper than skinoren by 300 - 500 rubles.

The active ingredient is the same: 15% azelaic acid.

°▪○* See azelic gel composition:

°▪○* Azelic 15% (azelaic acid) instructions for use:

°▪○* Azelic method of application: I applied the gel on clean, dry skin of the face (all over the face), with a thin layer 2, sometimes 1 time per day, and a 30-gram tube was enough for me for 2 months.

°▪○* Azelaic acid effect on the skin: at the beginning of the application, after applying the gel, I felt tingling and itching, which disappeared after a few minutes, after a few days, the side effects ceased to occur at all. In addition, when using azelic, I felt increased dryness and tightness of the skin, while I did not notice an increase in greasiness. One more nuance: if the product is unevenly distributed, after drying, white stains can be observed, which are easy to erase with your fingers or a powder brush, but you must not forget to do this before going out to people.

°▪○* Azelic gel before and after photos

Judging by the indications for use, azelic should fight acne or blackheads. Will the gel help get rid of blackheads, internal acne?

I tried to take a photo almost every week of treatment, I share with you my observations. ATTENTION, THERE WILL BE PHOTOS OF ACNE BELOW (do not watch for the faint of heart).

There are internal, not inflamed acne, black dots, peeling of the skin.

Photo AFTER A WEEK of application of azelic:

There are many small red pimples, the skin is flaky.

Photos AFTER TWO WEEKS:

The pimples have calmed down, the internal ones are in place, the black dots are in place, there is peeling.

Photo AFTER THREE WEEKS:

Apparently, again a hormonal surge - the pimples are a little inflamed, the cream from la roche pose is applied to the face, so peeling is not visible.

Photo AFTER A MONTH:

All problems are in place.

Photo AFTER A MONTH AND A WEEK:

The number of pimples has increased.

Photo AFTER A MONTH AND THREE WEEKS:

Pimples have calmed down, black dots are clearly visible.

Photo AFTER TWO MONTHS:

Peeling, black dots, internal acne did not go away.

1. Doesn't fight acne
2. Does not cope with internal acne;
3. Doesn't remove blackheads.

Azelaic acid for acne has proven to be a weak weapon. I can recommend mechanical cleansing of the face as an effective, but temporary remedy for this ailment, azelic acne gel do not recommend.

,,,,,,,,,,,,,,,,,,,,

Pharmacy cosmetics for acne-prone skin:

,,,,,,,,,,,,,,,,,,,,

Azelaic acid is a unique component used as a base for the preparation of many cosmetic preparations. It is one of the common remedies for skin discoloration, inflammation and acne. The use of acid helps to give the skin a healthy, natural look.

Azelaic acid, preparations based on which are successfully used to eliminate skin defects, is one of the carboxylic acids. A certain amount of this substance is also formed in the human body during lipid metabolism. For the needs of the pharmaceutical industry, this substance is obtained as a result of the industrial processing of cereals: wheat, barley and rye.

Properties

The popularity of azelaic acid is due to its beneficial properties.

Among them stand out:

• anti-inflammatory. The remedy has a calming effect on the skin, removes inflammation and redness;
• antibacterial. The tool actively fights microorganisms that cause acne and other skin defects;
• smoothing. The surface layers of the epidermis are polished, the skin is leveled;
• bleaching. The tool prevents the appearance of melanin, helps to improve complexion, lighten age spots and scars from rashes;
• oxygen-saturating. Oxygen is delivered to the cells of the dermis, which activates metabolic processes. The pores are little polluted, the development of acne is reduced.

Indications for use

Azelaic acid, preparations made on the basis of this substance, are used to treat a wide variety of skin defects.

These are:

• acne - blockage of the sebaceous glands;
• increased pigmentation;
• rosacea is a chronic dermatological pathology of the skin, in which pustular and other rashes are present;
• acne, other rashes;
• seborrhea;
• rosacea;
• demodicosis is a pathology caused by the activity of ticks.

Contraindications and side effects

In some rare cases of acid use, side effects are observed.

The most frequent of them are:

• minor redness of the skin;
• feeling of numbness;
• burning;
• hyperemia and peeling of the skin;
• temporary increase in sensitivity;
• mild itching;
• tingling or pinching.

Contraindications:

• excessive sensitivity to the constituent elements of the remedy;
• children's age up to 12 years.

The article discusses effective drugs with azelaic acid in the composition.

It is prescribed with caution:

• during pregnancy;
• during lactation.

Application in cosmetology

Preparations made on the basis of azelaic acid have become a common remedy for various skin diseases.

Against acne and demodicosis

Acid affects the skin in several ways:

• First of all, it destroys propionic bacteria, which are the cause of inflammation of acne. When applied, the pores are kept clean, which is a prerequisite for the methodical elimination of acne and the prevention of their secondary detection.
• The drug has a comedolytic property, that is, it reduces the number of comedones or blocks the pores.
• The use of acid helps to effectively eliminate old skin cells by natural exfoliation.
• With the help of a cream or ointment Skinoren Gel, the main element of which is azelaic acid, demadecosis is treated. This requires long-term complex therapy.

Rosacea and pigmentation

Azelaic acid in various cosmetic forms reliably cures rosacea at all stages of the disease.

Such a drug has the following properties:

• keratolytic;
• antibacterial;
• vascular strengthening;
• anti-inflammatory;
• antioxidant.

Once in the layers of the epidermis, the acid activates the release of a number of free fatty acids - inflammation provocateurs, and also helps to reduce the production of melanin. The same treatment is carried out for hyperpigmentation. The cream brightens problem areas of the skin and prevents their further spread.

Peeling

Azelaic peeling is a method of superficial, painless effect on the skin.

It is applied in cases:

• rosacea (spider veins);
• rosacea (non-infectious chronic inflammation);
• folliculitis (inflammatory lesions of the hair follicles);
• smoothing fine wrinkles;
• hyperpigmentation. This removes the outer layer of the skin. Peeling whitens pigmented spots, and the skin acquires a uniform tone.

This method is easy to use, almost devoid of restrictions and side effects.

As a method for facial skin rejuvenation, it is allowed to be used at almost any age. The greatest effect of the procedure is achieved in cases where it is performed by a professional cosmetologist. Home cleansing does not guarantee the maximum result, but the effect will be. In addition to this, the development of side effects and complications is possible.

Instructions for use of azelaic acid

Azelaic acid is used according to the instructions for use.

The main requirements are that:

• dosage and duration of therapy are determined individually;
• before the procedure, the treated surface is qualitatively cleaned and dried;
• cream or gel is smeared with a thin layer and gently rubbed with your fingertips;
• it is prescribed to treat the skin twice: in the morning and in the evening;
• if irritation does not stop during treatment, the frequency of application of the drug per day should be reduced to once or the therapy with azelaic products should be completely abandoned;
• the cream should not get on the mucous membranes of the mouth, nose, lips, and also in the eyes;
• the entire face will not require more than 2.5 cm of cream.

Features of use during pregnancy and lactation

During pregnancy and subsequent feeding of the child, acid preparations can be used provided that the benefit from the treatment of the mother outweighs the risk to the fetus or the baby born. Before using the remedy, you need to consult with your doctor. In any case, the use of acid and its derivatives should be done with caution.

Azelaic acid preparations

Age spots and acne are traditionally treated with medicines containing acid. In such cosmetics, azelaic acid is most often used as the main substance. Its content in these products is minimal, but the skin is provided with vitamins and health for a long time.

Azelik

The composition of this cream is based on a bacteriostatic action against acne. Regular use reduces the production of acne-causing fatty acids. The appearance of comedones is sharply reduced. During the effect of the cream on the process of keratinization of epidermal cells, the growth and activity of melanocytes responsible for hyperpigmentation slows down.

Acid levels the surface of the skin, brightens. There are no traces of exposure after treatment. The cream should be applied to a pre-cleaned surface.

For this purpose, one of the cleansing cosmetics is first applied to the face, then it is removed with a towel. Acne is visibly reduced after 4 weeks of use. Uneven relief, fresh scars and scars are straightened. The maximum result is achieved after 2-3 months of using the cream.

Azix-Derm

The main dosage form of the drug is a 20% topical cream. Contains an active element - azelaic acid and binding components. Produced for the local elimination of acne and pathological hyperpigmentation.

The drug is characterized by antimicrobial action against bacteria that cause acne, not only on the outer area of ​​the skin, but also in the sebaceous glands. In parallel with this, there is an anti-inflammatory effect on defective skin.

Acne-marked skin is cleansed and dried. It is recommended to apply the cream in a thin layer on the face, neck and, if necessary, on the upper chest area. The subsequent cleaning of the skin from impurities is carried out with water and a mild cleanser.

The cream should be used regularly 2 times a day for at least 1 month. In case of irritation, the dose of the cream should be reduced or applied once a day. Temporary cancellation of therapy and its resumption after the irritation disappears are allowed.

Skinoclier

Azelaic acid in the composition of the drug under consideration has antibacterial properties, has an anti-inflammatory effect, eliminates skin swelling and irritation. It has a keratolytic effect, that is, it removes dead skin cells.

Unlike other analogues, Skinoclear acts not only in the outer layers of the skin, but also in the depths of the epidermis, in the ducts of the sebaceous glands. The maximum result from the use of the cream is observed 2-3 months after the start of treatment. It is not a hormonal drug, does not affect the metabolism. The cream is allowed to be used from adolescence.

Skinoren

The multifaceted therapeutic activity of Skinoren gel based on azelaic acid allows it to be classified as an antibacterial, anti-inflammatory, keratoregulatory agent.

Indications for use:

• skin acne (pimples and blackheads);
• prevention and treatment of foci of post-inflammatory hyperpigmentation that appears after acne has healed.

The course of treatment is designed for 3 months, but improvement occurs after 3-4 weeks of using the drug. It should be consumed 2 times a day (morning and evening). Before application, the face should be washed and dried with a towel. To eliminate acne and blackheads, the gel is targetedly applied 2 times a day with a thin layer, and then rubbed a little.

There is also a cream of the same name on sale, which includes a little more azelaic acid than a gel (20% versus 15%).

It is suitable for people with dry and normal skin, while the gel is for patients with oily dermis. Since the active ingredients have little absorption, the product does not have any contraindications for women during pregnancy and lactation.

Acne Stop

Acne Stop is a topical drug used to normalize painful changes in the epidermis (acne) and benign hyperpigmentation of the skin (melasma). The therapeutic effect of the cream is based on the properties of its main ingredient - azelaic acid.

In addition to it, the content includes shaping agents and additional components: glycerin, benzoic acid, octyldodecanol, propylene glycol and some others. The drug is applied topically. To do this, you first need to clean the skin, dry it and apply the cream with soft rubbing movements.

For best results, continuous use is recommended. The duration of treatment is determined by the doctor and depends on the specific characteristics of the body. The drug has certain side effects that patients should be aware of.

Side effects:

Organs and systems of the body	Adverse manifestations
epidermal reactions	acne; hypersecretion of the sebaceous glands; rashes; inflammation of the lips (cheilitis).
Local reactions	burning; exfoliation of the outer layer of the skin irritation; sensory disturbances, sensations of numbness and tingling; dermatitis.
Immunity	There are symptoms of oversensitivity
Respiratory system	In patients with bronchial asthma, exacerbations of this disease are possible.

If any of these or other adverse effects appear during treatment with Acne Stop, you should immediately inform your doctor.

Azogel

Such a skin defect as acne is effectively treated with Azogel, the active element of which is azelaic acid. In addition to it, there are auxiliary substances, such as dimethicone, carbomeric interpolymer and others. The medicine eliminates the risk factors for acne, and not just the manifestations.

It has an antiseptic effect. The antibacterial effect is on the bacteria that cause acne. It also reduces the formation of dead skin cells in the dermis, due to which blackheads appear. The drug softens the skin and relieves irritation. The effectiveness of the cream is high even with long-term treatment.

If the use of a therapeutic drug causes irritation, the volume of the gel or the number of applications must be reduced. In case of special need, it is recommended to suspend the treatment process for several days. Azogel gel should be constantly used throughout the entire period of treatment.

Aknestop

Aknestop with the content of azelaic acid practically has a rejuvenating effect. The tool is successfully used to fight bacteria, new sudden acne formations.

In addition to acid, the basis of the drug is:

• propylene;
• glycerol;
• glycerol;
• other effective means.

The drug has not only external, but also internal effects, that is, it treats not only the consequences, but also the causes of acne formation. The use of the drug slows down the synthesis of fatty acids, which are the direct cause of acne.

Aknestop normalizes the processes in the follicular ducts, washes out unfavorable microorganisms. The duration of treatment is determined by the individual characteristics of the patient's body. The minimum period of therapy is 4 weeks, and in the case of melasma - 3 months.

How to make your own cream

Preparations with the presence of therapeutic acid are offered over the counter in pharmacies in the form of a cream, gel, powder. However, the cream is easy to prepare yourself at home. It will cost less, and there will be no worry that you bought a fake product.

To get the cream, you need to prepare in advance:

• powdered azelaic acid;
• sucrose;
• microlil. A special preservative that extends the shelf life of the finished cream;
• jojoba oil. If necessary, it is allowed to replace it with olive or rosemary;
• water.

The procedure for preparing the ointment is as follows:

1. Add 1.5 mg of azelaic acid to 16.5 ml of water, mix thoroughly. Clean glassware must be used for this. Since the acid is very poorly soluble in water, stir vigorously, whipping the composition.
2. After the final dilution of the acid, 1.5 ml of sucrose is introduced. Everything is mixed up again.
3. 7 ml of oil is poured into the second glass vessel, and both dishes are heated in a water bath.
4. After dissolving the sucrose, the contents of both mixtures are mixed until a homogeneous state is obtained.
5. Finally, you need to add a drop of microlil.

Azelaic cream, prepared with your own hands, is ready. The drug can be used daily. Already after 1-2 months it will be possible to observe a positive result of therapeutic acid - acne and black dots will begin to disappear quickly.

Useful videos about azelaic acid and preparations containing it

Azelaic Acid for Rosacea:

The mechanism of action of azelaic acid:

Heptane-1,7-dicarboxylic acid

Chemical properties

What it is? This substance is a dibasic limiting carboxylic acid. Its chemical properties are similar to other carboxylic acids.

It is a white crystalline powder, which is poorly soluble in water at a temperature of 20 degrees, but dissolves well in boiling water and ethyl alcohol.

Molecular weight of a chemical compound = 188.2 grams per mole.

The agent is actively used in production, as a thickener for silicone lubricants, as part of liquid heat carriers, oils for diffusion pumps, and frost-resistant lubricants.

Azelaic acid is widely used in cosmetology. Due to the fact that the substance has bacteriostatic activity against microorganisms that call. Also, the drug reduces the active production of fatty acids.

pharmachologic effect

Keratolytic, antibacterial, anti-inflammatory.

Pharmacodynamics and pharmacokinetics

Azelaic acid has a bacteriostatic effect on Staphylococcus epidermidis and Propionibacterium acnes. When applied topically, it reduces the production of fatty acids in the lipids of the surface layer of the skin. Proliferation processes are inhibited keratinocytes and the growth of abnormal melanocytes . The product has a depigmenting effect on the skin.

As part of creams and gels, the drug quickly penetrates into the upper layers of the skin (epidermis and dermis) and is practically not absorbed into the systemic circulation (less than 4%). The drug is excreted in the urine mainly unchanged and in the form of small chains. dicarboxylic acids .

Indications for use

The substance in the cream is used in the treatment of ordinary ( acne vulgaris), chloasma and other type hyperpigmentation melasma .

Gel based on Azelaic acid is used in the treatment of acne vulgaris and,.

Contraindications

Side effects

Usually the gel and ointment are well tolerated. Rarely in the first 2 weeks of treatment may occur: irritation, burning on the skin, itching , peeling .

These side effects usually go away on their own and do not require treatment.

Azelaic acid, instructions for use (Method and dosage)

Preparations use place in the form of gels and ointments.

Depending on the composition of the drug and the content of the active ingredient, the duration of treatment and dosage are different.

The preparations are applied several times a day to cleansed skin and lightly rubbed with massage movements.

The course of treatment with Azelaic acid is from several months. Treatment melasma takes at least 3 months. Between courses, you can take breaks of 1-2 months.

Overdose

Cases of drug overdose are not described.

Interaction

Data on drug interactions are not available.

Terms of sale

The medicine can be purchased without a prescription.

Storage conditions

Preparations based on this substance are stored in a place protected from children at room temperature.

Best before date

special instructions

During the use of ointments and gel, do not allow the product to get on the mucous membrane of the nose, mouth and lips. If during therapy there is a strong persistent skin irritation, it is recommended to reduce the frequency of use or stop treatment for a while.

During pregnancy and lactation

The substance practically does not penetrate into the blood plasma, is not excreted in breast milk, and does not adversely affect the development of the fetus. It can be used during pregnancy and lactation.

Preparations containing (Analogues)

The most popular preparations of Azelaic acid:, Azelex , Finacea , Acne-derma , Finevin , ointment Azelaic acid , Skinoclier .