Unfortunately, viral eye diseases are quite common in modern ophthalmology. And the drug "Poludan" is considered to be a fairly effective tool in the fight against infection. Eye drops relatively quickly relieve the main symptoms of the disease. However, many patients are interested in questions about what the medicine is and what properties it has. Are there any contraindications for admission? Is the treatment associated with side effects?

Release form and composition of the drug

It is immediately worth noting that this medicine is available in the form of lipofizat, which is contained in 5 ml glass bottles with a convenient dropper cap. It is in this form that you can purchase the drug "Poludan" in a pharmacy. Eye drops can be prepared by adding purified water for injection.

Lipophysate contains a polyribonucleotide complex consisting of potassium polyribouridylate in the amount of 0.107 mg and 0.1 mg of potassium polyriboadenylate. Potassium dihydrogen phosphate, sodium hydrogen phosphate and sodium chloride are used as auxiliary substances in the production.

As a rule, the package contains three vials of the drug at once, but in some pharmacies the drug can be purchased in smaller quantities.

Main pharmacological properties

As already mentioned, this drug is a complex of polyribonucleotides, which are obtained by biosynthesis. The active substances of the drug have a pronounced immunomodulatory and antiviral effect.

The solution quickly penetrates into the tissues of the eye, where it stimulates the formation of factors of the body's natural immune defense. In particular, the drug enhances the activity of T-killers, which provide rapid recognition of foreign proteins. In addition, the drug stimulates the production of endogenous interferons and cytokines.

The active substances of the drug penetrate into the blood serum and eye fluid, after which they are quickly excreted from the body.

Indications for the use of the drug

There are many diseases in which ophthalmologists recommend these particular eye drops. "Poludan" copes well with various viral infections by stimulating the body's natural immunity.

In particular, the indication for the use of the remedy is viral conjunctivitis, which is accompanied by inflammation of the mucous membrane of the eye, redness and burning in the eyes. An indication for use is also keratitis, in which there is inflammation of the cornea. This medicine is also indispensable for uveitis - inflammation of the choroid caused by the activity of viruses.

Naturally, these are far from all diseases in which Poludan (eye drops) is used. The instruction states that the drug is effective in keratoconjunctivitis, stromal keratitis, keratouveitis, keratoiridocyclitis, iridocyclitis and other inflammatory eye diseases. In addition, in combination with other drugs, these eye drops are used for neuritis of the optic nerves of viral origin.

"Poludan", eye drops: instructions for use

Of course, first of all, you need to prepare a solution from the existing lipophysate. Detailed instructions are included with the preparation. Two milliliters of purified water for injection should be injected into the vial (available at a pharmacy). Immediately it should be noted that the prepared product can be used no longer than seven days, and it should be stored only in the refrigerator.

The dosage in this case is individual. As a rule, with conjunctivitis, keratitis and keratoconjunctivitis, it is recommended to instill 1-2 drops in each eye. In the presence of acute symptoms, the procedure should be repeated approximately 6-8 times a day. As the main signs disappear, the number of instillations is reduced to 3-4 times a day. The duration of the course is determined by the doctor, but most often 7-10 days are enough for recovery. In some cases, the treatment is repeated after a certain time.

If instillations do not have the desired effect, the solution is injected directly into the subconjunctival space. Such procedures are also indicated for neuritis of viral origin, uveitis and some other diseases. To prepare a solution, lipofizat is diluted in 1 ml of purified water or novocaine. 0.5 ml of the solution is injected subconjunctivally once a day (less often - once every two days). The dosage for children is half as much - 0.25 ml of solution is used for injection.

As a rule, the course for an adult patient consists of 15-20 injections. For children, the solution is administered no more than 8-10 times.

Are there contraindications?

It is immediately worth noting that this medicine for the eyes has practically no contraindications. It is not prescribed only to patients with hypersensitivity to a particular component, although, according to statistics, this is extremely rare.

Many people are interested in the question of whether pregnancy is an obstacle to the use of the drug "Poludan". The eye drops have not been tested in women during pregnancy and lactation. However, many experts believe that this remedy is quite safe and cannot affect the development of the fetus in any way. In any case, patients during this period of life are categorically contraindicated to self-medicate - any medications can be taken only as prescribed by the attending physician.

Are side effects possible?

According to statistical studies, there are not so many inconveniences that may be associated with the use of the drug "Poludan". Eye drops in some cases can cause a slight burning sensation and redness of the eyes. In some patients, after instillation, one can notice the plethora of scleral vessels, which leads to an increase in the vascular pattern on the eye.

Injections of the solution in some cases can cause swelling of the lower eyelid. Some patients have petechial hemorrhages and increased intraocular pressure. It is worth noting that all these adverse reactions, as a rule, do not pose a serious threat and disappear on their own immediately after the drug is discontinued.

Drug interactions with other drugs

In fact, this medicine goes well with many medications. In particular, eye drops are often used in combination with antibiotics and other antibacterial and antiseptic agents.

But enzymatic drugs can adversely affect the effectiveness of eye drops, as they destroy endogenous interferon. In any case, be sure to tell your doctor about the drugs you are taking before you start using Poludan.

Eye drops "Poludan": price

Naturally, first of all, patients are interested in the cost of this medicine. In fact, the figures in this case can fluctuate quite widely, since the price depends on the manufacturer and the financial policy of the pharmacy itself. So how much will Poludan drops cost?

The price for one bottle on average ranges from 150 to 300 rubles. Naturally, the cost will be higher if you purchase the entire package. So the medicine can be categorized as quite affordable antiviral agents.

We continue to analyze effective drugs that help get rid of certain eye problems.

In this article, we will look at Poludan.

It is an antiviral drug based on a polyribonucleotide complex intended for the treatment of herpetic and adenovirus eye infections.

The principle of action of this drug is associated with the induction of the synthesis of endogenous interferons and cytokines in the blood and interferon in the lacrimal fluid.

Instructions for use

Compound

One vial for the preparation of drops contains a complex of polyuridylic and polyadenylic acids, potassium salt of polyriboadenylic acid, potassium salt of polyuribouridic acid.

Excipients are potassium dihydrogen phosphate, sodium hydrogen phosphate, sodium chloride.

Beneficial features

Poludan is a complex of polyribonucleotides, which are obtained by biosynthesis. The drug has immunomodulatory and antiviral effects.

The mechanism of action is associated with stimulation of the formation of immune defense factors in the body - endogenous interferons and cytokines, an increase in the activity of T-killers, which are responsible for the production of interferon gamma and recognition of foreign antigens.

After instillation, the solution penetrates well into the tissues of the eye, is determined in the blood serum and lacrimal fluid, and is eliminated from the body quickly.

Interaction with other drugs

This drug can be used simultaneously with other medicines for the treatment of viral infections and antibacterial agents.

Indications for use

The drug is prescribed for the treatment of viral eye lesions (primarily herpetic and adenovirus):

• choreoretinitis;
• keratoconjunctivitis;
• keratitis (description of the disease);
• keratouveitis;
• deep keratitis;
• iridocyclitis;
• virus-induced optic neuritis.

How to apply?

The drug is prescribed in the form of subconjunctival injections or eye drops.

In the form of instillation, the drug is prescribed for the treatment of superficial viral eye lesions, such as conjunctivitis, keratitis, keratoconjunctivitis.

After preparing the solution, it is instilled into the affected eye 1-2 drops, with acute symptoms, it is required to instill the eye 6-8 times a day, as you recover, the dose is reduced to 3-4 times a day.

The duration of the course of treatment should be determined by the attending physician, as a rule, it ranges from 7 to 10 days.

If the effect of the treatment is absent, subconjunctival administration of the drug is prescribed.

For the treatment of stromal keratitis, choreoretinitis, viral uveitis and optic neuritis caused by a virus, it is necessary to use injections of the drug under the conjunctiva.

To prepare the solution, the contents of the vial must be dissolved in 1 ml of water for injection or novocaine. The solution is injected subconjunctivally at a dose of 100 mcg once a day or every two days.

The course of treatment requires 15-20 injections. For the treatment of viral eye lesions in pediatric patients, a half dose is administered under the conjunctiva, the course of treatment requires 8 to 10 injections of the drug.

Contraindications

The drug can not be used in the presence of individual intolerance to any component.

Use during pregnancy

At this time, there are no data on the use of Poludan during pregnancy or breastfeeding, but most doctors say that the drug is not able to have a negative effect on the fetus.

Side effects

Among the side effects noted when using the drug in the form of eye drops, the most common are eye irritation and local allergic reactions in the form of burning, itching, plethora of scleral vessels.

In cases of drug administration in the form of an injection, it is possible to increase the vascular pattern of the mucous membrane of the eye or swelling of the eyelid. In some cases, the introduction of a solution into the anterior chamber of the eye is accompanied by a short-term increase in intraocular pressure, as a result of which small hemorrhages appear.

These phenomena are reversible and in most cases disappear on their own in 1-3 days after the end of the use of the drug.

Overdose

There are no data on cases of overdose with this drug.

Alcohol compatibility

It is not advisable to combine any antiviral drugs with the use of alcohol. Alcohol can weaken the medicinal effect of the drug, pervert it, or increase the manifestation of side effects.

Analogues

The following medicines are similar in purpose:

1. Okoferon. It differs from Poludan in its composition, but has a similar antiviral effect.
2. Ophthalmoferon. It differs in its composition, but has a similar antiviral effect. A positive feature is the absence of adverse reactions.
3. Aktipol. The composition includes aminobenzoic acid. It has, like Poludan, antiviral and immunomodulatory effects.

Price

The average cost of Poludan eye drops in Russian pharmacies is 170 rubles.

On the Ukrainian market, this drug costs an average 150 hryvnia.

Reviews on the Internet

Among the reviews about this drug there are both positive and negative. Many patients use it to treat viral eye diseases such as conjunctivitis, keratitis and others. Since the diseases are viral, the infection is quickly transferred from one eye to another and the person begins to experience a lot of discomfort.

Positive reviews. The use of drops in many who used it stops all unpleasant symptoms, such as burning, itching, severe redness, swelling, pain, tearing and pus stop. Some note that the medicine has a quick effect on the first day of use.

Others observed a positive effect from the drug not immediately, but after a few days, a week. Poludan has been successfully used to treat eye infections in childhood. In general, positive reviews guarantee the effectiveness of the drug and a guaranteed result.

negative feedback. There are also negative reviews about the drops. Patients complain about the short shelf life of the finished medicine and inconvenient packaging, that the medicinal solution is not sold ready-made, but must be prepared by oneself, buying water for injection in addition to the powder.

Drops did not help many who were treated for the simple reason that initially the doctors did not accurately establish the nature of the origin of conjunctivitis. It is worth noting that the drops help only with a viral disease, they do not treat a bacterial disease.

Examples

№1. They put me in the hospital, because I did not go to the doctor for a long time. At first, there was a slight pain in my eyes - I decided that it was because of the TV. A few days later, discharge started from my eyes, I washed my eyes with various infusions of herbs. Even later, rashes and itching appeared on the skin. Only then did I go to the clinic, where it turned out that it was a herpetic infection.

The doctor gave me a referral to the hospital, where I underwent a course of treatment with Poludan, who injected my conjunctiva. I was very afraid of injections, but my fears turned out to be completely in vain, since there was no pain at all, but I immediately felt relieved. I am very glad that the drug helped, as the doctor said that my already poor eyesight could have deteriorated greatly.

№2. A few months ago I caught viral conjunctivitis - the redness did not go away, my eye was inflamed, even tetracycline ointment did not help. After using Poludan drops, the result was not long in coming - the swelling of the eye decreased significantly, the redness disappeared, as did the itching.

You need to use drops for a long time, at least 2 weeks, but believe me, the effect is worth it. Another advantage of the drug is that it is immunostimulating, respectively, there is no need to take antibiotics.

After instillation, there is no sensation of a film on the eyes, that is, the drug does not affect visual acuity in any way. Of course, allergic reactions are also possible, but I have not observed any. Take care of yourself and be healthy!

Conclusion

Poludan is an ophthalmic drug that has an antiviral and immunomodulatory effect. The composition of the medicinal solution includes a polyribonucleotide complex, which is intended for the treatment of eye infections of a herpetic and adenovirus nature.

Drops perfectly interact with various drugs, so it can be safely used in the complex treatment of diseases. However, it should be carefully used simultaneously with enzyme preparations that can reduce the therapeutic and beneficial effect of Poludan.

The inconvenience in the use of the drug is that it must be prepared independently from powder and water for injection. In this case, the method of application is similar to any other drops that are instilled into the conjunctival sac with clean hands. The dosage and course of treatment are set by the doctor or the one that is attached to the instructions for the drug is observed. There are practically no contraindications to the drug, but there are many side effects, including eye irritation, swelling, etc.

Video

Inducer of endogenous interferon synthesis.
Preparation: POLUDAN®
The active substance of the drug: non appropriated
ATX encoding: S01AD
CFG: Antiviral and immunomodulatory drug for topical use in ophthalmology. Interferon synthesis inducer
Registration number: LS-002205
Date of registration: 03.11.06
The owner of the reg. Award: VEROPHARM OJSC (Russia)

Release form Poludan, drug packaging and composition.

Lyophilisate for the preparation of white eye drops.

1 vial
complex of polyadenylic and polyuridylic acids
100 units
including polyriboadenylic acid potassium salt (potassium polyriboadenylate)
100 mcg
including polyribouridylic acid potassium salt (potassium polyribouridylate)
107 mcg

Excipients: sodium hydrogen phosphate (sodium phosphate 2-substituted), potassium dihydrophosphate (potassium phosphate 1-substituted anhydrous), sodium chloride.

5 ml vials (1) complete with dropper caps (1) - packs of cardboard.
5 ml vials (3) complete with dropper caps (3) are cardboard packs.

Pharmacological action Poludan

Poludan is a biosynthetic polyribonucleotide complex of polyadenylic and polyuridylic acids (in equimolar ratios). Inducer of endogenous interferon synthesis. Stimulates the formation of mainly alpha interferon, to a lesser extent - beta and gamma interferons.
It has a pronounced antiviral and immunomodulatory activity.
Studies have shown that instillations and subconjunctival administration of Poludan promotes the production of endogenous interferon in the blood serum and tear fluid of patients with ophthalmic herpes. Interferon is determined in the blood serum and in the lacrimal fluid 3 hours after the administration of Poludan. High levels of interferon (110 U/ml in blood and 75 U/ml in tears) are maintained by daily injections of Poludan throughout the course. On the 2nd day after stopping the administration of the drug, interferon in biological fluids is practically not detected (its titer does not exceed 10 U / ml).
In addition, the introduction of Poludan led to a significant increase in the activity of natural killer cells, initially reduced in patients with ophthalmic herpes.
Studies of the influence of Poludan on immunological parameters in the in vitro system showed that the drug stimulates not only natural cytotoxicity, but also the functioning of other immunocompetent cells, in the regulation of the activity of which interferon plays a significant role.

Pharmacokinetics of the drug.

Data on the pharmacokinetics of the drug Poludan is not provided.

Indications for use:

- viral eye diseases (including adenovirus and herpetic conjunctivitis, keratoconjunctivitis, keratitis and keratoiridocyclitis, keratouveitis, stromal keratitis, iridocyclitis, chorioretinitis);
- optic neuritis (viral etiology).

Dosage and method of application of the drug.

The drug is used in adults in the form of eye drops and injections under the conjunctiva.
In the treatment of adenoviral and herpetic conjunctivitis, superficial keratoconjunctivitis and keratitis, Poludan's solution is instilled into the conjunctival sac of the diseased eye, 1-2 drops 6-8 times / day. As the inflammatory process subsides, the number of instillations is reduced to 3-4 times / day.
In the treatment of adenoviral and herpetic conjunctivitis, stromal keratitis and keratoiridocyclitis (keratouveitis), iridocyclitis, chorioretinitis, optic neuritis, the drug is used in the form of subconjunctival injections. Enter 0.5 ml (100 mcg) under the conjunctiva of the eye daily or every other day. The course of treatment is 15-20 injections.
Rules for the preparation of solutions
Poludan solution intended for instillation into the eye is prepared by dissolving the contents of the vial (200 μg) in 2 ml of distilled water.
To prepare a solution for subconjunctival injection, the contents of the vial (200 μg) are dissolved in 1 ml of sterile water for injection.

Side effects of Poludan:

When using the drug in the form of eye drops: rarely - allergic reactions in the form of itching, sensation of a foreign body in the eye, increased injection of the sclera, the appearance of individual follicles in the lower transitional fold.
With subconjunctival injection: sometimes - swelling of the lower eyelid and increased conjunctival injection.
When injected into the anterior chamber of the eye: rarely - a short-term rise in intraocular pressure, the appearance of hemorrhages in the anterior chamber, increased tyndalization of moisture in the anterior chamber.

Contraindications to the drug:

- Hypersensitivity to the components of the drug.

Use during pregnancy and lactation.

Data on the safety of the drug during pregnancy and lactation are not provided.

Special instructions for use Poludan.

Poludan should not be injected into the anterior chamber of the eye in case of keratoiridocyclitis with ulceration of the anterior surface of the cornea, conjunctivitis, the presence of pathogenic microflora in conjunctival cultures, infections of the teeth and paranasal sinuses.
Side effects disappear on their own after discontinuation of the drug within 1-3 days.
In therapeutic doses, Poludan is not pyrogenic.
The drug is compatible with antibiotics and conventional treatment of viral diseases.

Drug overdose:

Currently, cases of overdose of the drug Poludan have not been reported.

Interaction Poludan with other drugs.

With the simultaneous use of Poludan with enzyme preparations, due to the destructive effect of enzymes on endogenous interferon, the clinical effectiveness of Poludan decreases.

Terms of the storage conditions of the drug Poludan.

The drug should be stored in a dry, dark place at a temperature not exceeding 4°C. Shelf life - 4 years.
The prepared solution can be stored in the refrigerator for up to 1 week.

Conditions of sale in pharmacies.

The drug in the form of a lyophilized powder for the preparation of a subconjunctival solution is available by prescription.
The drug in the form of a lyophilized powder for the preparation of eye drops is approved for use as an over-the-counter drug.

Today, cases of eye diseases have become more frequent. For their treatment, effective eye drops are prescribed. But it is only allowed to use them after an accurate diagnosis. Poludan drops remain one of the most effective and popular.

This is a unique drug that effectively copes with inflammation of viral origin. Both adults and children can use the medicine, but only after being prescribed by the attending physician.

Action and what it is used for

Poludan is an antiviral drug based on a polyribonucleotide complex. It serves to treat herpetic and adenovirus infections that affect the organ of vision.

The therapeutic effect of the drug is based on the induction of the synthesis of endogenous interferons and cytokines in the blood and interferon in the lacrimal fluid.

One vial of treatment solution contains:

• complex of polyuridylic and polyadenylic acids,
• potassium salt of polyriboadenylic acid,
• potassium salt of polyribouridyl acid.

Additional components of the drug include:

• potassium dihydrogen phosphate,
• sodium hydrogen phosphate,
• sodium chloride.

Poludan refers to a complex of polyribonucleotides that were obtained by biosynthesis. The drug has immunomodulatory and antiviral effects.

It may also be useful for you to learn more about how you can cure and with which drops.

After instillation, the solution quickly penetrates into the tissues of the organ of vision, is determined in the blood serum and lacrimal fluid. Active components are very quickly excreted from the body.

Poludan drops are prescribed in the treatment of the following pathologies:

• keratitis- inflammation of the cornea of ​​​​the eye;
• keratoconjunctivitis- simultaneous inflammation of the cornea and conjunctiva;
• conjunctivitis- inflammation of the conjunctiva;
• keratouveitis– inflammation of the cornea and uveal tract;
• uveitis- inflammation of the choroid of the organ of vision;
• chorioretinitis- inflammation of the choroid of the eye with the involvement of the cornea;
• optic neuritis- primary inflammation of the optic nerve;
• iridocyclitis- inflammation of the iris and ciliary body of the eyeball.

The maximum effectiveness of the drug is observed in relation to adenoviruses and herpes viruses.

You may also be interested in learning about what it looks like and how it is treated.

On the video - how to bury your eyes:

Instructions for use

The positive effect of the use of drops is achieved only if the dosage and duration of treatment are correctly observed.

For adults

Drops are prescribed for the treatment of various superficial viral pathologies of the organ of vision. After preparing the solution, it is necessary to send it to the affected eye in the amount of 1-2 drops. If acute inflammation is observed, then drip the drug 6-8 times a day. But what does the inflammation of the lacrimal sac look like, and how is the treatment of such a disease, indicated

As you recover, reduce the number of instillations to 3-4 times a day. The duration of the therapeutic course is 7-10 days. It is determined by the attending physician, taking into account the type of pathology and its course. It is not worth using drops longer than the specified period, as there is a risk of addiction.

If there is no effect of therapy, then the doctor decides on the subconjunctival administration of the drug. In the treatment of stromal keratitis, choreoretinitis, viral uveitis and optic neuritis caused by a viral infection, drug injections under the conjunctiva are used.

To prepare a treatment solution, you need to take 1 ml of water and send the contents of the vial. Inject a solution of 100 mcg subconjunctivally 1-2 times a day. The course of therapy will be 15-20 injections. And here is what a subconjunctival hemorrhage of the eye looks like, you can see

For kids

Drops Poludan firmly entrenched in pediatrics in the treatment of various viral diseases of the organs of vision. Inject the solution under the conjunctiva in the amount of 1 drop 2-3 times a day. Treatment should not exceed 7-10 days. With the development of such unpleasant symptoms as burning, pain, pain, parents should consult a doctor. but why it may appear, you can find out from this article.

You can buy Poludan eye drops at any pharmacy without a doctor's prescription. The average price of a package (10 ampoules of 1 ml) is 500 rubles. Can also be used

Analogues

If for some reason it is not possible to purchase Poludan drops or side effects occur when they are used, then there is an alternative option - buying an analogue. These are drugs that are similar in purpose. The following analogues remain effective and most popular:

Release form, composition and pack

Lyophilisate for solution for injection white.

complex of polyadenylic and polyuridylic acids 100 IU;

including polyriboadenylic acid potassium salt (potassium polyriboadenylate) 100 mcg;

including polyribouridylic acid potassium salt (potassium polyribouridylate) 107 mcg.

Excipients: sodium hydrogen phosphate (sodium phosphate 2-substituted), potassium dihydrophosphate (potassium phosphate 1-substituted anhydrous), sodium chloride.

Clinical and pharmacological group

Antiviral and immunomodulatory product. interferon synthesis inductor.

pharmachologic effect

Poludan is a biosynthetic polyribonucleotide complex of polyriboadenylic and polyribouridylic acids. Inducer of synthesis of endogenous interferon and other cytokines. It has a pronounced antiviral and immunomodulatory activity. Enhances the activity of natural killer cells, initially reduced in patients with ophthalmic herpes, as well as other immunocompetent cells.

Injection stimulates the production of endogenous interferon in the blood serum and lacrimal fluid, which is determined 3 hours after the injection. A high level of interferon (110 IU/ml in the blood and 75 IU/ml in the lacrimal fluid) is maintained by daily injections throughout the course. On the second day after the termination of administration, it is practically not determined (the titer does not exceed 10 IU / ml).

Indications for use of the product

Assign adults and children with viral eye diseases:

adenovirus and herpetic keratoconjunctivitis;

keratitis and keratoiridocyclitis (keratouveitis);

stromal keratitis;

iridocyclitis;

chorioretinitis;

optic neuritis.

Dosing regimen

Subconjunctival.

Adults: dissolve the contents of the vial in 1 ml of water for injection or 1 ml of 0.5% novocaine solution and inject 0.5 ml under the conjunctiva every day or every other day. The course of treatment is 5-20 injections.

Children: dissolve the contents of the vial in 1 ml of water for injection and inject 0.25 ml under the conjunctiva every other day. The course of treatment is 8-10 injections.

In case of endothelial forms of herpetic keratoiridocyclitis, in the operating room: dissolve the contents of the bottle of Poludan in 1 ml of water for injection and slowly inject into the anterior chamber of the eye using a tuberculin syringe in a volume of 0.3-0.6 ml 2 times a week. The course of treatment is 3-5 injections.

In case of herpetic lesions of the posterior parts of the eye - chorioretinitis, uevitis, optic neuritis: dissolve the contents of the vial in 1 ml of water for injection or in 1 ml of 0.5% novocaine solution and inject periocularly (parabulbarno, retrobulbarno) 1 ml every other day. The course of treatment is 10-20 injections.

With fresh rashes of herpes zoster on the skin of the face, accompanying herpetic keratitis, the contents of two bottles of Poludan are dissolved in 10-20 ml of a 0.5% solution of novocaine and injected subcutaneously along the course of herpetic eruptions, every other day. These injections, carried out every other day, effectively contribute to the removal of pain and the regression of rashes. The course of treatment is 3-6 injections.

Injection of the product is prescribed by a doctor in the absence of effect from eye drops for 7 days.

Side effect

Allergic reactions are possible.

Subconjunctival injection causes slight swelling of the lower eyelid and increased conjunctival injection of the eye vessels.

With the introduction into the anterior chamber of the eye, a short-term increase in intraocular pressure, the appearance of hemorrhage in the anterior chamber of the eye is possible.

Contraindications to the use of the product

high susceptibility to product components.

The introduction of Poludan into the anterior chamber of the eye is contraindicated in

keratoiridocyclitis with ulceration of the anterior surface of the cornea;