Reg. No: 8771/08/13/14 dated 09/17/2013 - Expired
Tablets yellow with a greenish or orange tint, convex, marked "spa" on one side.
Excipients: magnesium stearate, talc, povidone, corn starch, lactose monohydrate.
60 pcs. - polypropylene bottles (1) - cardboard boxes.
Description of the medicinal product NO-SHPA based on officially approved instructions for use of the drug and made in 2009. Date of update: 01/28/2009
Myotropic antispasmodic. Drotaverine is an isoquinoline derivative that exhibits an antispasmodic effect on smooth muscles by inhibiting the enzyme phosphodiesterase type 4 (PDE4). Inhibition of the PDE4 enzyme leads to an increased concentration of cAMP, which inactivates the myosin kinase (MLCK) light chain, which in turn leads to smooth muscle relaxation.
Drotaverine inhibits the PDE4 enzyme in vitro without inhibiting the PDE3 and PDE5 enzymes. Apparently, PDE4 is functionally very important in reducing smooth muscle contractility, so selective PDE4 inhibitors can be effective in the treatment of hyperkinetic diseases and diseases associated with spastic conditions of the gastrointestinal tract.
Hydrolysis of cAMP in smooth muscle cells of the myocardium and blood vessels occurs mainly with the participation of PDE3, which explains the high effectiveness of drotaverine as an antispasmodic in the absence of a pronounced therapeutic effect on the cardiovascular system and serious cardiovascular side effects.
The drug is effective in spasms of smooth muscles of both nervous and muscular etiology. Regardless of the type of autonomic innervation, drotaverine acts on the smooth muscles of the gastrointestinal tract, biliary tract, as well as the genitourinary and vascular systems. Thanks to the vasodilating effect, No-shpa improves blood circulation in tissues.
In terms of intensity of action, drotaverine is superior to papaverine. The advantage of drotaverine is that it does not have a stimulating effect on the respiratory system, which was observed after parenteral administration of papaverine.
Suction and distribution
When taken orally and intramuscularly, drotaverine is rapidly and completely absorbed. C max is achieved within 45-60 minutes. It binds to plasma proteins (albumin and gamma and beta globulins) to a high degree.
Metabolism
After oral administration, it undergoes the effect of "first pass" through the liver, 65% of the dose of the drug is in the systemic circulation unchanged. Metabolized in the liver.
breeding
T 1/2 when taken orally - 16-22 hours, with intramuscular injection - 8-10 hours. After 72 hours, drotaverine is excreted from the body mainly in the form of metabolites, 50% - with urine, 30% - with feces. The unchanged drug is not found in the urine.
For oral administration:
- with spasms of smooth muscles of the gastrointestinal tract: peptic ulcer of the stomach and duodenum, gastritis, spasms of the cardia and pylorus, enteritis, colitis, spastic colitis with constipation and flatulence;
- tension headaches;
- in obstetrics and gynecology: algomenorrhea, to reduce the tone of the uterus during pregnancy, with threatened abortion.
- spasms of smooth muscles associated with diseases of the biliary tract: cholelithiasis, cholecystitis, pericholecystitis, cholangitis, papillitis;
- spasms of smooth muscles of the urinary system: nephrolithiasis, urethrolithiasis, pyelitis, cystitis, bladder tenesmus;
- during the period of opening during physiological childbirth to accelerate the opening of the cervix and reduce the total duration of labor.
- spasms of smooth muscles of the gastrointestinal tract: peptic ulcer of the stomach and duodenum, gastritis, spasms of the cardia and pylorus, enteritis, colitis;
- in obstetrics and gynecology: algomenorrhea, severe labor pains.
For parenteral administration:
For parenteral administration (if oral administration is not possible) as adjuvant therapy:
For oral administration
Adults the drug is prescribed in a daily dose of 120-240 mg (3-6 tablets) in 2-3 doses; single dose - 40-80 mg (1-2 tab.)
For children aged 1 to 6 years the recommended daily dose is 40-120 mg (1-2 tablets) in 2-3 doses; single dose - 20-40 mg (0.5-1 tab.).
For parenteral use
Adults i / m appoint 40-240 mg / day in divided doses for 1-3 injections per day.
At acute colic (renal or biliary) the drug is administered intravenously at a dose of 40-80 mg.
For shortening of the dilatation phase of the cervix during physiological labor at the beginning of the dilatation period administered intramuscularly at a dose of 40 mg, with an unsatisfactory effect, the injection can be repeated 1 time within 2 hours.
Determination of the frequency of adverse reactions:
- very often (> 1/10), often (> 1/100,< 1/10), иногда (>1/1000, < 1/100), редко > 1/10 000, < 1/1000), очень редко < 1/10 000).
From the digestive system: rarely - nausea, constipation.
From the side of the central nervous system: rarely - headache, dizziness, insomnia.
From the side of the cardiovascular system: rarely - palpitations;
Others: very rarely - allergic reactions (with parenteral administration, especially in patients with hypersensitivity to bisulfite).
Use during pregnancy and lactation
The use of the drug during pregnancy is possible only if indicated, when the intended benefit of therapy for the mother outweighs the potential risk to the fetus.
AT experimental studies when studying reproduction in animals and in a retrospective analysis of clinical data, it has been shown that drotaverine, when administered orally during pregnancy, does not have a teratogenic and embryotoxic effect.
Due to the lack of necessary clinical data, drotaverine is not recommended for use during lactation (breastfeeding).
The drug should be used with caution in arterial hypotension.
When the / in the introduction of the drug, the patient should be in the supine position because of the risk of collapse.
The composition of the tablets includes lactose (52 mg), so the drug in the form of tablets is not prescribed to patients with lactase deficiency, galactosemia or impaired glucose / galactose absorption syndrome.
The solution for injection contains sodium bisulfite, which can cause allergic reactions, including anaphylactic and bronchospasm, in sensitive individuals (especially those with asthma or a history of allergic reactions). In case of hypersensitivity to sodium metabisulphite, parenteral use of the drug should be avoided.
Content
The drug No-shpa is a myotropic antispasmodic. It reduces the tone of smooth muscles, lowers the excitability of internal organs, and dilates blood vessels. In terms of effectiveness, this antispasmodic surpasses all similar drugs. The medicine helps to reduce pain after application after 2-4 minutes.
Tablets No-shpa
Pharmacological properties make the drug effective against spasmolytic pain of various origins. No-shpa affects the smooth muscles of the cardiovascular, genitourinary, biliary, gastrointestinal systems. The country of origin of the medicinal product is Hungary. No-shpa is produced in tablets or in ampoules with a solution for intramuscular injections. The main active ingredient of the drug is drotaverine hydrochloride. The auxiliary components of the drug include:
- lactose monohydrate;
- corn starch;
- polyvidone;
- talc;
- magnesium stearate.
Properties
Drotaverine is an isoquinoline derivative that has an antispasmodic effect on smooth muscles by inhibiting the PDE 4 enzyme. This component of synthetic origin, due to the inactivation of the myosin kinase chain, relaxes the muscles. What helps Drotaverine? The substance is useful in the treatment of diseases during which spasms of the gastrointestinal tract appear, and for diseases accompanied by motor hyperfunction.
The property of No-shpa to increase blood circulation in the tissues leads to the ability to dilate blood vessels, which alleviates headaches and reduces fever. The drug is completely absorbed after oral and parenteral administration. It is 95% bound to the blood plasma and after the first metabolism, 65% of the dose unchanged enters the bloodstream. Drotaverine is metabolized in the liver, partially excreted after 10 hours, and completely - after 72 hours with urine and feces.
How it works
The chemical structure and pharmacological properties of No-shpa are similar to Papaverine, but it has a longer and more pronounced effect. The action of the drug is expressed by inhibition of the entry of calcium ions into the smooth muscle cells. This leads to an expansion of the coronary vessels, a decrease in the tone of intestinal motility and muscle fibers. Treatment with No-shpa does not affect the central nervous system and the autonomic nervous system.
What helps No-shpa
The drug is prescribed for adults and children from one year of age for medicinal purposes. Myotropic antispasmodic is effective for intestinal, renal, biliary colic. The drug No-shpa helps with stomach ulcers and duodenal ulcers. The antispasmodic is able to eliminate spasms with uterine tone during childbirth, significantly reducing their total duration. What else does No-shpa treat:
- chronic gastroduodenitis;
- muscle spasms of internal organs;
- biliary dyskinesia;
- bladder tenesmus;
- postcholecystectomy syndrome;
- spastic constipation;
- pylorospasm;
- chronic cholecystitis;
- urolithiasis of the kidneys;
- spasm of cerebral vessels;
- pyelitis, proctitis, spastic colitis.
At a temperature
There are two types of elevated temperature. When the whole body is hot, then the antipyretic suffices. When the hands and feet are cold, there is a spasm of the muscles, or convulsions, then antispasmodics are added to the treatment. The use of No-shpa at a temperature for children and adults as an independent drug is ineffective. The drug should be taken together with antipyretic and antihistamine drugs.
For a headache
The instructions do not say that No-shpa helps with headaches. However, the medicine does an excellent job with insomnia and fatigue, if they are caused by pressing headaches. It is not recommended to supplement the drug with other antispasmodic drugs, but it is allowed to be taken with analgin, paracetamol and other painkillers. If headaches are constantly present, then the medicine is not recommended to be used every day, it is better to see a specialist to determine the cause of the discomfort.
When coughing
Cough develops against the background of respiratory diseases. Their causes can be infections of viral, bacterial or fungal origin. No-shpa is useless when coughing, because it does not have an antitussive or expectorant effect. However, often a coughing fit is accompanied by spasms and suffocation, if the inflammation is localized in the bronchi or lungs. In this case, the antispasmodic will help alleviate the condition. The use of the drug will be effective together with antitussive and expectorant drugs.
Before childbirth
During pregnancy in expectant mothers, the need for the use of this drug occurs with a high tone of the uterus, which threatens miscarriage. No-shpa before childbirth helps to prepare the birth canal for the passage of the fetus. It is prescribed, as a rule, with drugs such as Papaverine, Buscopan, but in other dosage forms (injections, suppositories). Gynecologists say that with an antispasmodic, childbirth is faster and easier, both for the mother and for the child.
For toothache
Although the instructions do not indicate and doctors never prescribe No-shpa for toothache, in some cases pills for it are effective. Since the pain in the tooth is caused by irritation of the nerve endings, taking an antispasmodic is useless. However, many people report a reduction in toothache after No-shpa has been used. This is due to the placebo effect (self-hypnosis), which does not last long. Based on the foregoing, it is better to have an anti-inflammatory agent on hand that will actually eliminate the toothache until the time when you have the opportunity to visit the dentist.
With menstruation
Sometimes a woman has such painful periods that they resemble contractions. The pain manifests itself in the sacrum, abdomen and lower back throughout the menstruation, causing physical and psychological discomfort. No-shpa during menstruation neutralizes the action of prostaglandin, which allows you to more intensively remove the discharge. Since the cause of pain is the contraction of the uterus, the antispasmodic relaxes the clamped uterine muscles, neutralizing pain. It is permissible to drink up to 6 tablets per day during menstruation.
Under pressure
Elevated blood pressure occurs against the background of various pathologies. If the pressure is caused by vascular spasm, then it can be lowered with the help of an antispasmodic. Since No-shpa has a hypotensive effect and improves blood circulation, it can reduce blood pressure. When using this remedy, it is necessary to observe the dosage. Uncontrolled use of No-shpa under pressure can reduce it to critical numbers.
With cystitis
Inflammation of the bladder is a common disease, and both children and adults suffer from it. With untimely treatment, cystitis progresses and eventually becomes chronic. In order to prevent the development of pathology, it is necessary to take measures in time. Doctors often prescribe No-shpa for cystitis as an additional treatment, which can quickly relieve pain. Taking the drug removes heaviness in the lower abdomen and pain in the lumbar region. The muscles of the bladder immediately after the use of an antispasmodic relax, which helps the organ to function more efficiently.
With colic
A person at any time may experience severe pain caused by muscle spasm in the abdominal or retroperitoneal space. Contractions usually follow one after another. Depending on the localization, it can be renal, pancreatic, hepatic or intestinal colic. Excessive consumption of fatty foods, uncontrolled intake of alcohol, adhesions on the internal organs can provoke attacks. No-shpa for colic is a sure way to relieve pain. It should be remembered that the antispasmodic will not eliminate the cause of the disease. After anesthesia, you should immediately consult a doctor.
For pain in the intestines
Painful sensations in the intestines are not always associated with any disease. They can appear due to long-term use of medications, malnutrition, or motor disorders. The main difference from gastric pathologies is the independence of pain from meals. No-shpa for pain in the intestines helps to eliminate symptoms of any intensity. Prolonged pain in the abdominal cavity, which does not stop for several hours, is a dangerous condition in which an urgent need to consult a doctor.
For nausea
People often feel sick for a variety of reasons. Sometimes this condition comes after poor-quality food or overeating. Disorder of the digestive tract is also often accompanied by such a symptom. Often, along with nausea, a person experiences both weakness, severe sweating, and a feeling of heaviness in the stomach. This condition may indicate an exacerbation of cholecystitis, gastritis, or elementary food poisoning. No-shpa with nausea will relieve the initial symptoms, give time to get a consultation with a gastroenterologist and establish the cause of the disease.
No-shpa - how to take
Antispasmodics are sold without a doctor's prescription, but this does not mean that they can uncontrollably treat all diseases. How to take No-shpa, and what contraindications exist, is written in detail in the instructions. The optimal dose for adults is 1-2 tablets 2-3 times / day. The maximum daily dose for children is 120 mg in three divided doses. The drug is contraindicated for people with severe hepatic, cardiac or renal insufficiency, with arterial hypertension and individual intolerance to the components. Analogues No-shpa:
- Bioshpa;
- Vero-Drotaverine;
- Drotaverine forte;
- NOSH-BRA;
- Droverin;
- Spazmonet;
- Spazoverin;
- Spakovin.
During pregnancy
When a pregnant woman is registered with a antenatal clinic, doctors often recommend taking No-shpa for spastic pain in the digestive tract. However, it should be remembered that it is not advisable to take the medication too often, especially during lactation, since it has side effects in overdose. No-shpa during pregnancy treats spasms of the kidneys, intestinal colic. You can take a pill for a headache if it is caused by vasospasm.
After childbirth during breastfeeding, mothers often experience pain in the lower abdomen, so a single dose of No-shpa will not hurt. A large dose of the drug enters the milk, which affects the health of the baby. For this reason, taking an antispasmodic before and after childbirth should be negotiated with a gynecologist. If a woman needs to undergo a long course of treatment with drotaverine, then it is better to refuse breastfeeding for this period.
The drug No-shpa is a pharmacological drug belonging to the group of antispasmodics. The main indications for the use of Noshpa are diseases of the gastrointestinal tract, muscle spasms, kidney pathologies, as well as gynecological ailments. In addition, No-shpa is used at high temperature in a toddler. It is the question of how to properly use No-shpu at a temperature in children that we will find out further.
Indications for the use of the drug
Initially, it is required to consider whether No-shpu can be given to a child, and in what cases it is indicated. This is the right question, because very often parents give drugs to children without thinking about whether it is possible to do this. Before resorting to the use of no-shpa, it should be clarified in which cases it is allowed. It is allowed to resort to the treatment of children with no-shpa in the presence of the following diseases:
- Diseases of the genitourinary system. In frequent cases, babies get cold of the genitourinary organs, resulting in pain. You can relieve pain in a baby with the help of No-shpa.
- Diseases of the gastrointestinal tract. You can eliminate pain in diseases such as gastritis, colitis and enteritis with the help of drotaverine (the main active ingredient in No-shpa).
- With the development of severe pain. You can give children No-shpu if the baby complains of a headache.
- At high temperatures, No-shpa helps to expand the blood vessels, as a result of which the baby's well-being improves.
- Spasms of peripheral vessels.
It is important to note that after the pain in the child is stopped, parents will definitely need to go to the hospital for examination.
It's important to know! This drug is an antispasmodic, but not a drug, so the improvement in well-being after using the drug is temporary, while the active substance has an effect.
Often parents give the drug to children with the development of symptoms of cough and runny nose. It should be understood that no-shpa for children with such indications is not appropriate. This is due to the fact that the tool does not have a positive effect on the muscles of the upper respiratory tract, so it is absolutely useless.
It's important to know! The ideal option for using No-shpa for children is after a preliminary consultation with the attending physician.
Age dosages for children
If parents resort to the use of no-shpy, then they should know that the drug can be used from the age of one. Why, because for children who are under 1 year old, it is strictly contraindicated to use and prescribe the remedy, since it negatively affects the nervous and cardiovascular systems. No-shpa is not desirable for use in children over a year old, but up to a year in children, its use should be categorically excluded, since the consequences of its use can cause serious and irreversible consequences. Consider what dosages are recommended for children of different ages.
Children from 1 year to 6 years
For fever, children under the age of 6 are better off using antipyretic drugs that have a softening effect, such as Nurofen, Ibuprofen or Paracetamol. Why resort to the use of No-shpa for children at such an early age? This is due to the fact that No-shpa gives a longer effect, and also eliminates painful spasms of smooth muscles, while the above components only eliminate the symptoms of fever for 4-6 hours. For children from 1 to 6 years old, the dosage of no-shpa is 40 to 120 mg. In tablet equivalent, this is from 1 to 3 pieces in the amount of 2-3 times a day.
About how much medicine you can give your baby, you should check with your doctor. For children aged 1 to 5 years, it is strictly forbidden to give the drug in the form of whole tablets. The baby cannot swallow the pill, so there is a risk that the pill will simply get stuck in the larynx. In addition, the tablets are bitter in taste, so children are reluctant to swallow them. At such an early age, tablets can be crushed, after which the resulting powder is mixed with syrup, and allowed to be taken by the baby. Pediatricians recommend that if it is not possible to bring down the high temperature in a baby, especially with cold extremities, when symptoms of febrile spasms develop, 1/3 or ½ No-shpa tablets should be given along with Paracetamol. After that, the fever will decrease and return to normal after a short time.
It's important to know! If the crumbs have icy arms and legs, then this precedes the development of vasospasm. To exclude further development of complications, give the baby ½ tablet of no-shpa. For children from one year to 3 years, one fourth tablet should be given.
Children from 6 to 12 years old
At the age of 6, No-shpa can be given fearlessly, but be sure to observe the correct dosage. The daily dose for children of this age group is from 80 to 200 mg. As for children at a younger age, No-shpa should be used if the baby develops complications, manifested in the development of vasospasm. At this age, the risk of developing vasospasm is quite low if the child does not have pathologies of the cardiovascular and nervous systems.
When the temperature rises, No-shpu should be given to the baby along with Paracetamol, which will enhance the effectiveness of the drug. At this age, the dosage is ½ tablet or one whole tablet. Parents are advised to check with their doctor what dosage should be used.
It's important to know! Despite the fact that a child over the age of 6 is already more independent, parents should still consult a doctor about the need and rationality of using No-shpa.
Children over 12 years old
The dosage of no-shpa for children over the age of 12 is close to adult doses. The daily dosage is 120-240 mg or 4 to 6 tablets per day. This dosage is recommended for children who develop spasms of smooth muscles. At high temperature, when the child has cold feet, 1-2 tablets should be given along with Paracetamol.
It's important to know! It is forbidden to bring down the temperature with no-spoy for several days, as the body gets used to the active substance of the drug.
Contraindications
Without special need, it is not recommended to use no-shpu for children. Doctors recommend that parents, only if the baby develops the first signs of vasospasm, should use this drug.
The main contraindications about this drug are as follows:
- Use for children under one year is strictly prohibited.
- With pathologies of the kidneys and liver, the use of the drug is strictly prohibited.
- If children have pathological disorders of the cardiovascular system, as well as with low blood pressure, then it is forbidden to resort to the use of the drug.
- The drug is contraindicated in asthma.
When taking no-shpa, it should be borne in mind that the baby may experience intolerance to the components of the drug. The consequence of this phenomenon may be the development of allergic symptoms, so the first dose of the drug should be carried out with caution.
Very often there are cases when a stomach cramp or a sharp headache is taken by surprise. In this state, it is very difficult to concentrate. And it is very important to take an antispasmodic in time, which will not only relieve the symptom for a while, but completely remove the cause of the discomfort that has arisen. To date, one of the most popular remedies for spasms of smooth muscles is No-Shpa. The popularity of this drug is associated with its wide range of applications.
The main advantage of "No-Shpa" can be considered the minimum number of side effects, unlike other means of the same spectrum of action. Very often, "No-Shpu" is prescribed for pain in.
Composition, release form, packaging
"No-Shpa" are yellow round tablets with "spa" embossed on one side. The release form varies depending on the recommendations for use:
- Cardboard box with blisters in the amount of 6 to 24 pcs.
- Plastic vial with the number of tablets from 60 to 100 pcs.
- Solution for injections - 2 ml.
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Before using this medication, be sure to consult a doctor. 
Pharmacological properties
Drotaverine is rapidly absorbed into the soft tissues of the stomach. After absorption, 65% of the accepted amount enters the blood supply system. The highest concentration in the body is observed within an hour after ingestion. Drotaverine evenly spreads through the tissues and easily enters the cells. In humans, the active substance "No-Shpy" is processed in the liver, its metabolites actively interact with glucuronic acid.
Important!Drotaverine completely leaves the body in 72 hours. Over 50%« No-Shpy» excreted by the kidneys, and approximately 30% - through the gastrointestinal tract.
Indications for use
"No-Shpa" is a universal remedy that is indicated for use for children.
The main indications for the use of the drug:
- rapid contractions of smooth muscles associated with diseases of the biliary tract: cholecystolithiasis, cholangiolithiasis, cholecystitis, pericholecystitis, papillitis;
- muscle spasms of the genitourinary system: urethrolithiasis, and others.
Additionally, "No-Shpu" is prescribed for such deviations: - spasms of smooth muscles of the gastrointestinal tract: stomach ulcers, irritable bowel syndrome, flatulence and diseases with the presence of acute abdomen syndrome (for example,).
- headaches and migraines.
Did you know?On average, a migraine attack lasts 15 to 24 hours. Unfortunately, it manifests itself at least once a month, and is also inherited by children.
Therefore, in the presence of such diseases or symptoms, it is imperative to be examined by a doctor and begin treatment.
At what age can children be given
When young children experience discomfort from pain, parents are ready to do anything to save the baby from such torment. And very often they do not discuss it with the doctor. With migraines and high fever, with pain in the stomach, parents immediately give the child “No-Shpu” thoughtlessly. There are situations when parents give "No-Shpu" to children with a strong.
Before using "No-Shpa" for treatment or as a way to rid a child of unpleasant symptoms, you should understand the instructions for using No-Shpa tablets for children.
Important!« No-Shpa» does not affect the upper respiratory tract and does not have an expectorant effect. Therefore use« No-Shpu» not recommended in these situations.
The age of the child is also important. "No-Shpu" can be given to children with, observing all prescriptions and daily dosage. This medicine is not recommended for young children. This is due to the lack of the required number of conclusions about the effect on the children's body during the research.
Therefore, when choosing this particular medicine, you need to study all the information about whether it is possible to give "No-Shpu" to children, as well as the dosage of the drug and the age category.
Dosage and administration
In order for treatment and prevention to be more effective, and the spasm to be relieved in a short time, you need to know how to take No-Shpu correctly and in what quantity. Doctors prescribe this medicine in daily doses of 120-240 mg, which should be divided into two to three doses. A single authorized dose of 80 mg is one tablet. 
With special care, you need to approach the use of this drug for children: it is prescribed in the form of tablets, in the amount of 80 mg in several doses for children from 6 to 12 years old. And children over 12 years old - 160 mg two or four times for the whole day. Before using at a temperature, you should always consult with your doctor how much No-Shpa can be given to a child.
Contraindications and side effects
Despite all the advantages and positive aspects of this drug, it should be remembered that, like any medical product, "No-Shpa" has a number of contraindications:
- intolerance to the active substance of the drug.
- severe renal or hepatic insufficiency.
- severe heart failure.
- due to the lack of in-depth clinical studies of No-Shpu, it is not recommended to use No-Shpu for children under one year of age.
- during the period .
But, despite all the ease of use, you need to competently approach the use of No-Shpa, since intolerance to one or more components or improper use can lead to side effects: - Headache or dizziness.
- Disorders of the gastrointestinal tract.
- In rare cases -.
- Cardiopalmus.
Overdose
An overdose of the active substance - drotaverine can disrupt the functioning of the cardiovascular system, this can lead to complete cardiac arrest. Full recovery after an overdose of the drug should be carried out under the strict supervision of a physician. To avoid unpleasant consequences, you should undergo an examination and pass all the necessary tests before starting use, and also remember the dosage of "No-Shpa" at a temperature for children. 
Terms and conditions of storage
To date, "No-Shpa" continues to be very popular, although it has "settled" in the first-aid kits of our parents for a long time. The shelf life is designed for five years, the main thing is to follow simple storage rules and not use No-Shpa after the expiration date.
This is a universal drug that will alleviate the patient's condition and relieve unpleasant symptoms. The main thing is to remember the basic rules of use and dosage. And do not forget also about the age group - especially from how old you can give "No-Shpu" to children.
There are medicines that should be in the first aid kit of any family. One of these drugs is No-shpa, which has established itself as a highly effective antispasmodic used to relieve pain of a different nature. Due to the fact that the medication is dispensed without a prescription, it is often used uncontrollably, without taking into account the contraindications and side effects that No-shpa has, like any of the medicines.
The active substance of this drug is drotaverine, which has an antispasmodic effect on smooth muscles and therefore is able to cope even with severe spastic pains.
How to use No-shpu correctly, and in what cases will the drug bring real benefits?
Properties and action of No-shpy
The drug No-shpa refers to myotropic antispasmodics. It contains the active substance drotaverine, which affects the smooth muscles of the genitourinary, gastrointestinal, cardiovascular, biliary systems.
Drotaverine relaxes the muscles, as a result of which spasms weaken, which makes it possible to use the drug to relieve pain in diseases of the gastrointestinal tract and diseases that are accompanied by motor hyperfunction. The active ingredients of No-shpa accelerate blood circulation in the tissues, which leads to vasodilation, i.e. relieves headaches and relieves feverish conditions.
The excipients that make up No-shpa contribute to better absorption of the drug: talc, starch, stearate, polyvidone, lactose monohydrate.
Forms of release of the drug: ampoules for intramuscular injections and more popular - tablets.
Drug analogues:
- Drotaverine;
- Spazmonet;
- Papaverine;
- Spasmol;
- Nokhshaverin.
In terms of composition and action, No-shpa tablets resemble Papaverine, but have a more pronounced effect. No-shpa relieves pain of various origins, prevents the penetration of ions into organs, lowers the tone of smooth muscles, but at the same time does not adversely affect the state of the nervous system.
The most popular analogue of No-shpa is Drotaverine tablets, which have the same principle of action and composition, and have the same effect, and are also much cheaper. Does it make sense to buy No-shpu if there is an inexpensive drug with a similar effect?
No-shpa is a patented, original drug, and the presence of a patent imposes special obligations on the manufacturer - production control, compliance of raw materials with quality and safety must be ensured. Before getting on the shelves, the drug undergoes a series of clinical trials, where it is subject to strict requirements.
Drotaverine, on the other hand, refers to generics, i.e. is an off-patent drug with much lower requirements. This does not mean that Drotaverine may be ineffective and adversely affect health, but it explains the great popularity of No-shpa and justifies its high cost.
How long does No-shpa work? No-shpa is the best at coping with spasms, i.e. with involuntary muscle contraction, causing pain. If conventional analgesics (for example,) are used to relieve such pains, the effect will be short-lived, while No-Shpa acts directly on the cause of the pain, as a result of which unpleasant symptoms do not return for a long time.
What helps No-shpa
The drug can be used both as a main and as an auxiliary therapeutic agent for a number of pathological conditions:
- spastic;
- Pyelite;
- Tenesmus;
- Proctitis;
- colic;
- Algodysmenorrhea;
- Spasm of the arteries;
- Endarteritis;
- Dyskinesia of biliary organs;
- Spasm of cerebral vessels.
In addition, No-shpa is used for certain conditions, to alleviate and relieve unpleasant symptoms.
For headache
The instruction does not indicate that No-shpa eliminates headaches. But, if pain in the head is associated with fatigue or insomnia, then the drug actively copes with the elimination of compressive headaches.
Note! No-shpa from is not recommended for use simultaneously with other antispasmodics, but it can be used together with drugs from the analgesic group (paracetamol, etc.).
With constant headaches, it is not recommended to use No-shpu regularly, it is better to consult a doctor to find out the cause of the painful condition.
At a temperature
At elevated temperatures, if it is accompanied by muscle spasms (convulsions), along with antipyretic children and adults, it is recommended to give an antispasmodic - No-shpu.
As an independent remedy for lowering the temperature, No-shpa is not effective.
During pregnancy
When carrying a child in pregnant women, a high is often observed, which threatens. To relieve spasm of the muscles of the uterus, No-shpa is often prescribed.
Before childbirth, No-shpu is often prescribed in combination with Buscopan or Papeverin in order to prepare the birth canal for the normal passage of the fetus. Gynecologists say that this is quite effective in helping to facilitate future childbirth, both for the mother herself and for the child.
When coughing
No-shpa does not have an expectorant and antitussive effect, therefore it is useless when coughing.
But if the inflammation that causes is localized in the lungs and bronchi, then attacks can provoke spasms in the airways and suffocation. In such conditions, No-shpa helps to significantly alleviate the condition, but not cure the cough.
During menstruation
Pain during menstruation can be so intense that it resembles labor pains. The cause of such pain is uterine contractions - the antispasmodic No-shpa has a relaxing effect on the muscles of the uterus and neutralizes pain.
During painful periods, it is possible to drink up to six tablets of the drug per day.
With cystitis
No-shpa can be prescribed as an adjunct treatment for pain relief. The medicine quickly relieves heaviness in the lower abdomen and relieves pain that occurs in the lumbar region.
After taking No-shpa, the muscles of the bladder relax, as a result of which the organ begins to function more efficiently.
Under pressure
If the increase is associated with vasospasm, then No-shpa can reduce blood pressure, because. the drug improves blood circulation and has a beneficial effect on blood vessels.
When reducing with the help of No-shpy, the dosage of the drug must be observed, because. uncontrolled intake can reduce blood pressure to critical numbers.
For pain in the intestines
If intestinal cramps are not associated with pathologies, but are caused by poisoning, motor disorders, long-term medication, then No-shpa will help to cope with pain of any intensity.
However, with prolonged pain in the intestinal area, you should not try to stop the pain with an antispasmodic, but it is better to immediately consult a doctor.
With colic
In the abdominal or retroperitoneal space, sharp cramping pains may occur. Colic can be hepatic, renal, pancreatic, intestinal, depending on the location of their localization. Their appearance can cause uncontrolled intake of alcohol, the abuse of fatty foods and other reasons.
No-shpa in this case quickly neutralizes the pain, but does not eliminate their cause. Therefore, in such conditions after anesthesia, it is better to seek medical advice.
How to drink No-shpu
You can drink an antispasmodic in tablets, 1-2 pieces at a time, twice or thrice a day. In the form of injections (in ampoules), the drug is injected into a vein at a dosage of 40 mg to 80 mg.
Babies, whose age is from 6 to 12 years old, should consume no more than 80 mg per day, and this amount is divided into 2-4 doses. No-shpa after 12 years of age can be used by children at a dosage of up to 160 mg of the drug, also stretching it over several doses.
Adults should not exceed the daily dosage of the drug - 240 mg, and a single dose should not be more than 80 mg.
In some cases, the use of No-shpa is possible without medical advice, but before that it is necessary to study all contraindications to the drug and recommendations for its use. Self-administration of drugs as an anesthetic should not exceed two days - after this period, it is worth contacting the doctors to identify the causes of pain.
Who is contraindicated for No-shpa:
- With severe;
- With intolerance to galactose;
- With severe pathologies of the liver or kidneys;
- With violations of intestinal absorption;
- With intolerance to the components of the drug.
Taking an antispasmodic is not allowed for children who are under the age of six.
The usual average dose for adults is daily 40-240 mg of drotaverine hydrochloride (divided into 1-3 doses per day) intramuscularly. For acute colic (biliary and) 40-80 mg intravenously
