Nyak treatment drugs. How to treat various forms of UC? Treatment of the acute stage

Nonspecific ulcerative colitis is a rare and not fully understood pathology. Some consider genetic predisposition as the main reason, others - the influence of external factors, including alcohol, smoking, stress and malnutrition. We will not dwell on the causes of the disease for a long time - this publication is devoted to such an issue as the treatment of ulcerative colitis with medications and folk remedies.

What is ulcerative colitis

Ulcerative colitis is a chronic disease of the large intestine, which is part of the digestive system where water is removed from undigested food, leaving behind digestive waste. The large intestine ends in the rectum, which, in turn, passes into the anus. In patients with ulcerative colitis, the lining of the intestine becomes inflamed, leading to abdominal pain, diarrhea, and rectal bleeding. Next, we will talk about the features of the disease of nonspecific ulcerative colitis, the symptoms, the treatment of which will be discussed in detail.

Ulcerative colitis is often associated with an inflammatory disease such as Crohn's disease. Together, these two ailments can be combined under the concept of inflammatory bowel disease. Ulcerative colitis, along with Crohn's disease, are chronic diseases that can last for years or decades. Men and women suffer equally. The development of pathology most often begins in adolescence or early adulthood, but there are also cases of this disease in young children.

Very often, residents of Europe and America, as well as people of Jewish origin, are diagnosed with ulcerative colitis. The population of Asian countries and representatives of the Negroid race are more fortunate in this regard - their pathology is extremely rare. For unknown reasons, an increased frequency of this disease has recently been observed in developing countries. There is also a high likelihood of colitis in those whose relatives are familiar with such a diagnosis.

What are the causes of ulcerative colitis

Reliable factors for the development of colitis have not been identified, and at present there is no convincing evidence that this is an infectious disease. Most experts are inclined to believe that ulcerative colitis occurs due to impaired functioning of the immune system in the intestine. In this case, abnormal activation of immune cells and proteins occurs, the activity of which leads to inflammation. The predisposition to abnormal immune activation is inherited genetically. Research scientists have found about 30 genes that can increase the likelihood of developing colitis. Read more about ulcerative colitis of the intestine, symptoms, treatment of the disease.

Symptoms of the disease

How does ulcerative colitis present? Treatment of the disease is primarily determined by its type. Common symptoms of ulcerative colitis include rectal bleeding, abdominal pain, and diarrhea. But besides these symptoms, there is a wide range of other manifestations of the disease. The variability of manifestations reflects differences in the degree of development of the disease, which are classified depending on the location and severity of inflammation:

  • Ulcerative proctitis is limited to the rectum, and mild rectal bleeding may be the only symptom. More severe lesions are accompanied by sudden uncontrollable diarrhea and tenesmus - a false urge to defecate due to muscle contractions of the intestine.
  • Proctosigmoiditis is a combination of inflammation of the rectum and sigmoid colon, symptoms include sudden diarrhea, tenesmus, and rectal bleeding. Some patients have bloody stools and seizures.
  • Left-sided colitis is localized in the rectum and spreads up the left side of the colon (to the sigmoid and descending), manifested by bloody diarrhea, a sharp decrease in weight, pain in the abdomen.
  • Pancolitis, or universal colitis, involves the entire colon and symptoms include abdominal cramps and pain, weight loss, fatigue, night sweats, fever, rectal bleeding, and diarrhea. This type of ulcerative colitis is much more difficult to treat.
  • Fulminant colitis is a very rare and most severe form of the disease. Patients suffer from severe dehydration due to chronic diarrhea, abdominal pain, and often shock. This form of colitis is treated with intravenous drugs, and in some cases it may be necessary to surgically remove the affected part of the colon to prevent it from rupturing.

Most often, any of the listed forms of colitis remains localized in the same part of the intestine, it rarely happens that one passes into another, for example, ulcerative proctitis can develop into left-sided colitis.

Diagnostics

The primary diagnosis is made on the basis of complaints and symptoms - bleeding, diarrhea, abdominal pain. In addition, laboratory studies are carried out:

Scientific studies also indicate that the presence of the protein calprotectin in the feces can be considered as a sign of the development of ulcerative colitis. Currently, new diagnostic diagnostic methods are used:

  • video capsule endoscopy;
  • CT scan;
  • MRI enterography.

Therapy Methods

Treatment for ulcerative colitis includes medical and surgical methods. Surgery is indicated for severe forms of colitis and life-threatening complications. Ulcerative colitis is characterized by periods of exacerbation and remission, which can last from several months to several years. The main symptoms of the disease appear during relapses. Relief most often occurs as a result of treatment, sometimes exacerbations can go away on their own, without outside intervention.

Medical therapy

Since ulcerative colitis cannot be completely cured with drugs, their use has the following goals:

  • overcoming relapses;
  • maintenance of remissions;
  • minimizing side effects from treatment;
  • improving the quality of life;
  • reducing the risk of developing cancer.

Medicines are divided into two large groups:

  • anti-inflammatory agents, in particular corticosteroids, glucocorticoids, 5-ASA compounds;
  • immunomodulators, for example, Methotrexate, Cyclosporine, Azathioprine.

5-ASA preparations

5-aminosalicylic acid, or Mesalamine, is a drug that is similar in chemical structure to aspirin, which has long been used to treat arthritis, tendinitis, and bursitis. However, unlike 5-ASA, aspirin is not effective against ulcerative colitis. The drug "Mesalamine" can be delivered directly to the site of inflammation with the help of an enema, but taking the drug inside is more effective. Initially, physicians had a problem - with oral administration of the drug, most of the active substance is absorbed when passing through the stomach and upper part of the small intestine before it reaches the large intestine. Therefore, to increase its effectiveness, 5-aminosalicylic acid has been modified into chemical forms that remain stable before entering the lower digestive system.

As a result, the following preparations were obtained:

  • "Sulfasalazine" - a stable structure of two molecules of 5-aminosalicylic acid, has been successfully used for many years in inducing remission in patients with mild to moderate colitis, reduces inflammation, abdominal pain and bleeding. Side effects include heartburn, nausea, anemia, and a temporary decrease in sperm count in men.
  • "Mesalamine" is a modification of 5-ASA, consisting of an active substance coated with a protective thin shell of acrylic resin. The drug passes through the stomach and small intestine without damage, and when it reaches the ileum and colon, it dissolves, releasing 5-ASA. This drug is also known as "Asacol", it is recommended to take it according to the following scheme - to eliminate exacerbations, 800 mg three times a day, and to maintain remission - 800 mg twice a day. If Mesalamine is ineffective, then corticosteroids are prescribed.
  • "Olsalazin", or "Dipentum" is a modification of 5-ASA, in which the molecules of the active substance are connected to one inert molecule, which also allows you to reach the focus of inflammation.

It is worth listing other derivatives of 5-aminosalicylic acid, which are used in the treatment of ulcerative colitis:

  • Balsalazid, or Colazal.
  • "Pentaza".
  • enema and suppositories "Rovaz".
  • Lialda.

Corticosteroids

These compounds have been used for many years to treat patients with moderate to severe Crohn's disease and ulcerative colitis. Unlike 5-aminosalicylic acid, corticosteroids do not require direct contact with inflamed intestinal tissues to be effective. These are powerful anti-inflammatory drugs that are taken orally. Once in the blood, they have a therapeutic effect on the entire body. Treatment of ulcerative colitis with these drugs is very effective. In critically ill patients, corticosteroids are given intravenously (eg, hydrocortisone). These compounds act faster than 5-ASA and the patient usually improves within a few days. If a patient has ulcerative colitis of the intestine, treatment with these drugs is used only to overcome relapses of the disease, they are not used as maintenance of remissions.

Side effects of corticosteroids

They depend on the dose and duration of administration. Short courses of treatment with Prednisolone are well tolerated and have virtually no side effects. With long-term use of high doses of corticosteroids, some complications, including serious ones, may develop. Among them:

  • rounding the oval of the face;
  • the appearance of acne;
  • increase in the amount of hair on the body;
  • diabetes;
  • weight gain;
  • hypertension;
  • cataract;
  • increased susceptibility to infections;
  • depression, insomnia;
  • muscle weakness;
  • glaucoma;
  • mood swings, irritability;
  • osteoporosis, or thinning of the bones.

The most dangerous complications of taking corticosteroids include aseptic necrosis of the hip joints and a decrease in the ability of the adrenal glands to produce cortisol. In a disease such as ulcerative colitis, treatment with corticosteroids requires extreme caution and medical supervision. These drugs should only be used for the shortest amount of time. Treatment usually begins with the appointment of Prednisolone at a dosage of up to 60 mg per day. As soon as the condition begins to improve, the amount of the drug is gradually reduced by 5-10 mg per week and stopped. The use of corticosteroids must necessarily be accompanied by an increase in the calcium content in food and the intake of preparations of this element. This is necessary to reduce the risk of developing osteoporosis.

Attention! Corticosteroids should be taken as directed and under the supervision of a physician. Self-medication with these drugs can lead to irreversible consequences.

Of the modern corticosteroids, drugs such as Budesonide and Golimumab can be distinguished.

Immunomodulators

These are drugs that weaken the body's immune system and stop the activation of immunity, leading to the development of ulcerative colitis. Usually, the immune system is activated when pathogens enter the body, an infection. But in the case of colitis or Crohn's disease, body tissues and beneficial microorganisms become the object of immune cells. Immunomodulators reduce the intensity of tissue inflammation by reducing the population of immune cells and disrupting their production of proteins. In general, the benefits of using such drugs in the treatment of ulcerative colitis outweigh the risk of infection due to a weakened immune system.

Examples of immunomodulators:

  • Azathioprine and Purinethol reduce the activity of leukocytes. In high doses, these two drugs are used to prevent rejection of transplanted organs and in the treatment of leukemia. In low doses, they are successfully used as a therapy for a disease such as ulcerative colitis. Treatment, reviews of which can be read on clinic websites and medical forums, in most cases is effective.
  • "Methotrexate" combines anti-inflammatory and immunomodulatory properties. Used in the treatment of psoriasis and arthritis, effective against ulcerative colitis. A side effect is the development of cirrhosis of the liver, especially in patients who abuse alcohol, as well as pneumonia. In addition, the drug should not be used during pregnancy.
  • Cyclosporine, or Sandimmun, is a powerful immunosuppressant that is effective for quickly controlling the development of severe colitis or delaying surgery. Side effect - increased blood pressure, convulsions, impaired renal function.
  • Infliximab, or Remicade, is a protein that acts as an antibody against proteins produced by immune cells. It is used to treat colitis and Crohn's disease if corticosteroids and immunomodulators have been ineffective.

Surgery

Surgery for ulcerative colitis usually involves removal of the colon and rectum. This procedure also eliminates the risk of developing cancer in these parts of the digestive system. Surgical treatment of ulcerative colitis is indicated for the following groups of patients:

  • patients with fulminant colitis and toxic megacolon (widening of the colon wall);
  • people with pancolitis and left-sided colitis who are on the verge of developing colon cancer;
  • patients who have experienced many relapses over the years, refractory to treatment.

Recently, an innovation has been introduced that involves replacing the removed colon with a cover made from the intestine. It serves as a reservoir similar to the rectum and is emptied regularly through a small tube. This operation is called an ileostomy.

Ulcerative colitis: treatment, diet

It is likely that a special diet may benefit patients with ulcerative colitis. However, there is no evidence to support that treatment for ulcerative colitis is more effective with dietary changes. Despite extensive research, no single diet has been shown to slow the progression of the disease. In this regard, general recommendations can be made based on a healthy, balanced diet rich in fruits, vegetables, cereals, lean meats, nuts, and fish. Patients should limit their intake of saturated fats. During an exacerbation, grated soft foods are recommended to minimize discomfort. Further you can read about the alternative treatment of ulcerative colitis.

ethnoscience

The main methods used in the treatment of a disease such as ulcerative colitis are discussed above. Alternative treatment of the disease acts more as a supportive one. In the arsenal of natural remedies there are honey, seeds, leaves and roots of plants, vegetables. If you have ulcerative colitis, herbal treatment may be helpful and reduce inflammation. Below you can find some traditional medicine recipes used for colitis.

Mix dried chamomile, yarrow and sage flowers in equal parts. 3 art. l. Pour the mixture with a liter of hot boiled water and let it brew for 4-5 hours. Take according to Art. spoon 7 times a day for a month, then reduce the dose to 4 times a day. The tool is considered a good prevention of exacerbations of colitis.

Traditional healers advise for ulcerative colitis of the intestine to reinforce the treatment with the use of potato juice. Grate the peeled tubers and squeeze the juice. Drink half a glass half an hour before meals.

A decoction of strawberry or bird cherry leaves, linden tea, an infusion of calendula flowers, herbal preparations, parsley root - whole volumes can be written about natural remedies for such an ailment as ulcerative colitis. Treatment, reviews of the results of which can be read in magazines and newspapers such as "Healthy Lifestyle", cannot replace the one prescribed by the doctor. No matter how diverse and touted folk recipes are, they cannot be considered as the main treatment. Do not forget that the treatment of ulcerative colitis with folk remedies is only a measure that can accompany the main methods of therapy. Also, check with your doctor before using any prescription.

The term "UC" hides a very dangerous disease of the gastrointestinal tract (GIT), referred to as nonspecific ulcerative colitis. It is accompanied by intestinal bleeding, abdominal pain, fever, weight loss. If the treatment of NUC is started late, then the disease becomes chronic, which is difficult to cure.

Therefore, after an apparent improvement, an exacerbation often occurs. The severe form of the disease can cause complications such as intestinal ruptures and colon cancer. With such complications that threaten the life of the patient, surgical intervention is indicated. Since drug treatment of the disease brings only minor results, the treatment of NUC with folk remedies is literally the only type of therapy that brings results.

Causes of nonspecific ulcerative colitis

Unfortunately, the causes leading to this disease are still unknown. But experts identify several factors that can cause NUC:

  • hereditary predisposition;
  • transferred infections;
  • imbalance of the immune system;
  • neuropsychological features and emotional instability;
  • diseases of the gastrointestinal tract;
  • bad ecological situation.

Disease begins with damage to the rectum and spreads throughout the healthy part of the colon, the submucosal and mucous layers are affected, the inner surface of the intestine is covered with ulcers of various sizes.

Nervous disorders contribute to the rapid spread of the disease and its severe course, so the treatment is also aimed at restoring psychological balance.

Forms and stages of UC

The severity of the disease indicates what kind of treatment the patient needs. But all its types are aimed at restoration of the mucous and submucosal membranes of the colon and rectum.

Therefore, in the treatment of NUC with folk remedies, herbs are chosen that have enveloping and wound-healing properties.

Stages of nonspecific ulcerative colitis

According to the course of the disease, NUC can be divided into stages:

  1. Chronic. The disease develops into a chronic disease if treatment is not started on time.
  2. acute. The appearance of the first signs and symptoms of the disease.
  3. Recurrent. An aggravation that occurs after an apparent improvement.

Forms of nonspecific ulcerative colitis

According to the severity of the disease can be divided into forms:

  1. Easy.
  2. Medium severity.
  3. Heavy.

With a mild form, the patient's condition is satisfactory, loose stools occur no more than 5 times a day, possibly with a slight admixture of blood. The severe form is accompanied by fever, loose stools from 8 times a day with an admixture of blood, pus and mucus. Severe forms of the disease are treated exclusively in the hospital.

Treatment of NUC with folk methods

Alleviate the course of the disease and cope with it in the future appropriate phytotherapy helps, that is, NUC is treated with herbs.

Phytotherapy sometimes remains the only treatment option when drugs are powerless against the disease, and it is too early to resort to surgical intervention.

Suitable medicinal herbs

Herbal infusions should have a mild effect, envelop damaged areas of the colon and rectum, have a wound healing effect, and stop bleeding.

Therefore, herbs used to treat UC should have all of these properties. Besides herbal infusions replenish fluid loss and restore the water-salt balance of the body. For the treatment of NUC, folk remedies use herbs and other plant components that have been proven for centuries:

  1. Leaves of raspberries, strawberries, currants: help the liver fight disease.
  2. Dried blueberries: cleanse the intestines of putrefactive substances and help fight cancer cells.
  3. Nettle: improves blood clotting, relieves inflammation, cleanses the intestines from decay products.
  4. Peppermint: helps to cope with emotional instability, diarrhea, relieves inflammation, spasms, has an antibacterial effect.
  5. chamomile: powerful antimicrobial and antibacterial action, relieve spasms.
  6. yarrow: has bactericidal properties, cleansing the intestines from harmful microorganisms, stops diarrhea.
  7. snyt: has a wound healing effect, relieves inflammation, relieves pain, copes with constipation.
  8. Bloodroot: heals sores, stops diarrhea.
  9. pomegranate peel: infusions will stop diarrhea, cope with pathogens, relieve inflammation.
  10. Celandine. cope with nervous tension, fights harmful microorganisms, relieves inflammation, helps fight ulcers.
  11. Sagebrush: cleanse the intestines from destructive microorganisms.
  12. St. John's wort: restores intestinal motility, has anti-inflammatory, fights purulent impurities in the stool.
  13. Highlander bird: heals wounds, relieves spasms and inflammation.
  14. Alder: astringent and wound-healing effect, stop intestinal bleeding.

Medicinal infusions are prepared from these herbs. You can combine them into collections, as well as brew each separately. To prepare the fees, it is enough to take each of the necessary herbs in equal proportions. To increase a certain effect, increase the proportion of the desired herb. Glycerin can be added to decoctions.

Treatment of the chronic stage of UC

Chronic ulcerative colitis can be accompanied by both diarrhea and constipation. Therefore, the treatment of NUC with folk remedies should take into account these features:

  1. Treatment of colitis accompanied by diarrhea. Herbal preparations must necessarily include herbs with fixing properties, for example, yarrow. Take chamomile and yarrow herbs in a ratio of 5: 1, add one part of nettle, St. John's wort and rose hips to them. You will get a herbal collection, the infusion of which will have an increased antibacterial effect, stop diarrhea, cope with decay and stop bleeding. Brewed in a ratio of 1 tbsp. collection on a glass of water. The infusion should be put in a water bath, and then let it brew for several hours (you can put it in a thermos overnight). You need to drink a glass before meals.
  2. Treatment of colitis accompanied by constipation. Herbal preparations, which contain a laxative herb, for example, gout, will help restore motor skills. Take in equal parts chamomile, goutweed, nettle, mint, valerian root and blueberries. Pour three tablespoons of the collection into a thermos and pour three cups of boiling water, leave overnight. Drink one glass before meals. See others in a separate article.

Treatment of the acute stage of UC

Helps to treat the acute stage strongly brewed green tea because it has strong antimicrobial activity. But tea bags will not work, you need to purchase large-leaf tea.

plays an important role in the treatment of acute colitis chamomile. The infusion from it should also be strong: you need to take 4 tbsp for a glass of water. The infusion should be heated in a water bath for about 20 minutes, then strain. Take it half a cup after a meal.

St. John's wort able to stop diarrhea in an acute attack of colitis. Grass is taken at the rate of one tablespoon per glass of boiling water. Infuse for about half an hour and take a third of a glass three times a day before meals.

Treatment of relapses

At this time, you need to take fees that increase blood circulation and contribute to the speedy healing of ulcers.

Also in the infusions should participate herbs that improve blood clotting: St. John's wort, nettle, nettle, pepper knotweed. These herbs are recommended to be added to other medicinal collections.

In all cases, the treatment of NUC with folk remedies is very effective. enemas with sea buckthorn oil. It promotes cell regeneration and the fastest healing of wounds and sores. In a small pear, collect 50 ml of oil and enter into the rectum in the supine position. Sea buckthorn enemas are recommended to be done at night. And in the morning you need to take 1-2 tablespoons. oils inside and always on an empty stomach.

NUC and homeopathy

Although homeopathic methods are no longer new methods of treatment, sooner or later there is a desire to give oneself into the hands of a homeopathic doctor. In this case, you need to choose an experienced, proven and qualified doctor.

The treatment of UC with homeopathy depends on the individual characteristics of the patient, therefore, only a conversation with a homeopathic doctor takes a lot of time, up to several hours. Based on described symptoms and other characteristics the doctor will select an individual treatment, which can start from conventional herbal medicine, and end with massage or acupuncture.

Bolotov-Naumov effect

Those who are trying to cope with the disease have probably heard of Dr. Naumov and the Bolotov-Naumov effect. Studies have led to the fact that the cause of ulcerative colitis is the malfunction of the muscular valve - the pylorus, which separates the stomach cavity from the duodenum.

With a low contractility, it remains open for a long time, and as a result of which the two environments (stomach and intestines) mix, which leads to various diseases of the gastrointestinal tract. The contractility of the valve is disturbed due to the frequent use of alkaline foods. Help restore the pylorus Dr. Naumov's recommendations:

  1. In 30 minutes sucking salt after meals, preferably large.
  2. In the chronic course of the disease, he recommends cook cakes from vegetables.
  3. Enter into the diet in small portions: meat, mushrooms, fish, cottage cheese, kefir, pickled vegetables.
  4. Drink infusion of wormwood 1.5 hours after eating.
  5. Cook kvass from celandine on whey and drink it on a spoon every two hours.

With the right approach, the treatment of NUC according to Naumov brings tangible results. When eating acidic foods, the tone of the pylorus increases, which is called the Bolotov-Naumov effect.

Nonspecific ulcerative colitis is a very dangerous disease that should not be left to chance and think that it will go away on its own. About 10% of cases are fatal. Therefore, regular treatment will help to weaken the disease and serve as a prevention of serious complications.

Ulcerative colitis, or non-specific ulcerative colitis (often abbreviated as NUC), is a disease in which inflammatory processes develop in the rectal mucosa. The disease is characterized by a transition to a chronic stage with a change of exacerbations and periods of remission. Among the main causes of nonspecific ulcerative colitis, there is a combination of genetic factors predisposing to pathology and the negative influence of the external environment. The prevalence of ulcerative colitis ranges from 40 to 117 cases per 100,000 population. The most vulnerable part of the population is 20-40 years old. The highest frequency of lethal cases from NUC is noted when the disease proceeds at lightning speed, in the first year of the disease, with its severe course, malignant tumors develop rapidly, and also 10 years after the manifestation.

Etiology of nonspecific ulcerative colitis

Ulcerative colitis is a disease with not fully understood triggers. It is known that the presence among close relatives of patients with ulcerative colitis of the intestine or, also characterized by a chronic inflammatory process of the intestinal walls, increases the risk of developing UC.
Most often, nonspecific colitis is recorded at a young age, from 20 to 25 years, the second most vulnerable age group is 55-65 years.
There is evidence that ulcerative colitis is provoked by infections of a bacterial and viral nature, but there is no clear correlation yet.

Reliable data include some environmental factors that influence the onset of the disease and its exacerbation. The most fully studied are such as taking oral contraceptives and certain hormonal drugs, smoking, and passion for certain types of diets. The dependence on hormonal drugs and fluctuations in the natural hormonal background (mainly with an increase in the level of estrogen in the blood) is indirectly confirmed by statistical data: among adults, the number of female patients diagnosed with NUC exceeds the male part by almost 30%.

There is a correlation between an increased risk of developing the disease and long-term use of non-steroidal anti-inflammatory drugs, the presence of food allergies uncorrected by diet and / or medication, and severe or prolonged stress conditions.
The main theory of the onset of the disease is based on the presence of immunological factors and autosensitization of the patient's body.

Protective and preventive factors in UC

Various studies have identified factors that reduce the likelihood of developing ulcerative colitis, increasing the effectiveness of its diagnosis and treatment.

  • It is likely that the operation of appendectomy for true appendicitis, transferred at a young age, reduces the risk of developing ulcerative nonspecific colitis.
  • Breastfeeding is a potential protective factor: ulcerative colitis is less common in women who do not suppress lactation after childbirth.
  • The relationship between intestinal colitis and tobacco smoking is ambiguous: among the smoking population, the prevalence of ulcerative colitis is higher than among non-smokers. However, the frequency of the disease increases dramatically in those who quit smoking, in connection with which a study was conducted on the effect of nicotine on the manifestation of symptoms of ulcerative colitis. Based on the results, it was concluded that it is possible to include nicotine preparations (in the form of patches, etc.) in the general course of drug therapy for nonspecific ulcerative colitis.
  • Oleic acid is considered a means of preventing the onset and development of the disease, having the ability to block chemical compounds responsible for inflammation of the intestinal walls, it can be included in the diet of patients and patients at risk in order to prevent the development or exacerbation of the disease. The average recommended dose is based on acid ingestion in foods, such as 2-3 tablespoons of olive oil.

Ulcerative colitis: symptomsdiseases

Ulcerative colitis of the intestine is characterized by a long, chronic nature of the course, in which the clinical picture of the disease combines periods of exacerbation and remission. The severity and specificity of symptomatic manifestations depends on the localization of the destructive process and its intensity, as well as the depth of tissue damage.

Ulcerative nonspecific colitis at the initial stage is accompanied by swelling and hyperemic changes in the intestinal mucosa. After a certain time (depending on the rate of development of the pathology, the body's resistance and the timeliness of the diagnosis of nonspecific colitis, the start of therapy), ulceration of the intestinal walls begins with an inflammatory lesion of the submucosal layer, and in a severe form of the disease, muscle tissue may also be involved in the process of destruction. Probably the formation of so-called pseudopolyps, narrowing of the intestinal lumen and other complications.

With the development of nonspecific ulcerative colitis, the symptoms are divided into intestinal and extraintestinal, depending on the localization of the manifestation. Both types of symptoms, depending on the stage of the disease and the general condition of the body, can manifest themselves both in a pronounced form and in a minimal or completely absent form.
Among the intestinal symptoms of nonspecific ulcerative colitis are:

  • the frequency of liquid, mushy stools with various inclusions (mucus, blood, purulent discharge);
  • the presence of false and imperative urge to defecate;
  • pain in the abdomen, mainly in the left lower quarter. However, depending on the localization of the pathology, there may be pain in the lower abdomen, accompanying false urges to defecate with pain. Pain with left-sided localization can be cutting, cramping, undulating, etc.;
  • appetite disorders (more often - decrease), weight loss, with a long acute stage up to cachexia;
  • violations of water and electrolyte balance of varying severity;
  • an increase in body temperature from subfebrile to febrile indicators (from 37 to 39 ° C);
  • general malaise, weakness, pain in the joints.

Extraintestinal manifestations with a high prevalence include skin inflammatory processes with spread to the subcutaneous tissue (pyoderma gangrenosum, erythrema nordularis), lesions of the mucous membranes of the mouth (aphthous and other stomatitis), manifestations of inflammation in the articular tissues (arthralgia, ankylosing spondylitis), organs of vision, and also the development of uveitis, episcleritis, primary sclerosing cholangitis, pathologies of the cardiovascular system, kidneys, liver, biliary tract, etc. is likely. In the presence of these diseases, especially in combination with intestinal symptoms, a diagnostic study of the gastrointestinal organs should be performed to identify the etiology a path for confirmation or an exception of nonspecific ulcer colitis.

Types of nonspecific ulcerative colitis: classification of the disease

Ulcerative colitis is divided into types depending on the localization of the inflammatory process, the course of the disease and its severity.
Classification of types of nonspecific ulcerative colitis according to the localization of inflammation:

  • with inflammation of the rectal mucosa, proctitis is diagnosed;
  • with a combined lesion of the mucous membranes of the sigmoid and rectum, they speak of nonspecific ulcerative proctosigmoiditis;
  • total damage to a significant part of the intestinal mucosa makes it possible to diagnose total nonspecific ulcerative colitis, the most severe form of the disease;
  • colitis, which is characterized by an inflammatory process in the left side, is singled out in a separate refined diagnosis as left-sided UC with an inflammatory process in the intestine located above the rectum and limited by the splenic flexure of the colon;
  • the remaining localizations are combined into a diagnosis of "regional ulcerative colitis" with specification of the location of the lesion.

Depending on the dynamics of the disease, its forms are distinguished:

  • acute;
  • chronic;
  • relapsing form of nonspecific ulcerative colitis.

The clinical picture and severity of symptoms make it possible to classify nonspecific ulcerative colitis according to the severity of the course:

  • ulcerative colitis of the intestine in mild form is characterized by mushy stools with a frequency of not more than 5 times within 24 hours, a satisfactory general condition, a small amount of impurities in the feces (blood, mucus, pus), the absence of other pronounced manifestations, including water and electrolyte disturbances balance and the resulting tachycardia and other complications. In laboratory studies, hemoglobin values ​​are usually normal, elevated body temperature is not recorded;
  • the average form of severity is accompanied by pain in the abdomen, rapid (up to 8 times) loose stools with impurities, the presence of subfebrile body temperature, signs of anemia, tachycardia;
  • in severe form, there is diarrhea, loose stools, 8 or more times a day, a significant amount of impurities in the feces, febrile body temperature (above 38 ° C), anemia (hemoglobin values ​​​​not more than 90 g / l), severe tachycardia, general condition is unsatisfactory up to severe. Prolonged internal bleeding can not only be accompanied by anemia, hypoproteinemia, beriberi, but also lead to hemorrhagic shock, which can be fatal.

Diagnostic criteria for the disease

Unambiguous diagnostic criteria for non-specific ulcerative colitis have not been developed due to the complex manifestation of the disease and the similarity of symptoms with various other pathologies. When making a diagnosis, differentiation with helminthic invasions, acute intestinal infections (dysentery), protozoal invasions (amebiasis), Crohn's disease, tumor formations in the colon cavity is required.
In general, the clinical manifestation of the disease and studies can accurately determine the presence of non-specific ulcerative colitis using the following diagnostic methods:

  • collection of anamnesis by studying the medical record and questioning the patient. Both complaints and information about the presence of close relatives with inflammatory and non-inflammatory bowel pathologies, a list of medications taken, trips to countries with a high epidemiological level for certain diseases, a history of intestinal infections, food poisoning, smoking, allergies and food intolerance in the patient;
  • data of a detailed physical examination of the patient with an assessment of heart rate, body temperature, blood pressure, body mass index, assessment of peritoneal (abdominal) symptoms, identification of the presence or absence of signs of expansion of the intestines, as well as examination of the oral mucosa, skin, sclera and joints;
  • examination of the anus, digital examination and / or sigmoidoscopy of the rectum;
  • survey radiography of the gastrointestinal tract;
  • total colonoscopy with the inclusion of ileoscopy in the study;
  • biopsy of the mucous membranes of the colon or other departments with local, regional inflammation;
  • Ultrasound of the abdominal organs, small pelvis, etc.;
  • laboratory tests of feces, urine, blood.

In order to differentiate the diagnosis, it is possible to prescribe other research methods, including magnetic resonance imaging, computed tomography, transabdominal and transrectal ultrasound examinations of the intestines, radiography with contrast injection, capsule endoscopy, and others.

Complications of the disease

Ulcerative colitis is a disease that requires constant therapy and compliance with doctor's prescriptions, both in taking medications and in following the rules of dietary nutrition. Violations of the therapy regimen, distortion of prescriptions and untreated forms of nonspecific ulcerative colitis, in addition to pathologies from various organs and the development of inflammatory processes in tissues not adjacent to the intestinal mucosa, can also cause serious complications requiring urgent hospitalization due to the high level of lethal outcomes of diseases. These include:

  • megacolon of a toxic variety, or an expansion of the intestine, more often of the transverse colon with a violation of the tone of the walls. An expansion diameter of 6 or more centimeters is characterized by severe intoxication of the body, exhaustion, without emergency therapy leads to death;
  • a pronounced inflammatory process in the mucous membrane in every 30 patients leads to perforation, perforation of the colon and is also the cause of total sepsis and death;
  • profuse intestinal bleeding leads to severe forms, exhaustion;
  • complications with localization in the perianal region: fissures, fistulous changes, paraproctitis, etc.;
  • According to studies, with a complete lesion of the colon up to the hepatic flexure, patients with ulcerative colitis for more than 10 years in history have a high risk of developing bowel cancer.

Extra-intestinal complications include pronounced pathologies and dysfunctions of the cardiac system, blood vessels (thrombophlebitis, thrombosis), kidneys, liver, etc. A long-term inflammatory process of the intestine has a significant effect on the entire body and, without effective therapy, causes disability and death of the patient.

Treatment methods for ulcerative colitis of the intestine: treatment and prevention of exacerbations

With NUC, treatment is selected depending on the location of the inflammatory process and the degree of coverage, the severity of the disease, the extent of the disease, the presence of extraintestinal manifestations and complications, as well as the risk of their development. The effectiveness of previous courses of treatment is also evaluated.
Nonspecific colitis in the mild stage and moderate course of the disease without exacerbations do not require hospitalization, and therapy can be carried out independently at home. Severe forms of the disease require a hospital stay for examination, relief of acute stages and treatment.

Nonspecific ulcerative colitis: diet of patients

Regardless of the stage of the disease, the severity of symptoms and the presence of exacerbations, it is strongly recommended that everyone adhere to the principles of sparing nutrition and a diet with the following dietary restrictions:

  • all foods containing coarse fiber that can irritate the inflamed intestinal mucosa. These include wholemeal flour, fruits, vegetables rich in fiber, cereals with preservation of the shell, legumes, nuts, etc.;
  • any dishes made with hot spices, marinades, high salt content, vinegar, etc.

When compiling a diet for patients with ulcerative colitis, it is recommended to focus on the following food groups and methods for their processing:

  • the basis of the diet consists of lean varieties of meat, poultry, fish, egg white, cottage cheese in the absence of contraindications to these products, which is associated with a high incidence of hypoproteinemia in this disease (lack of protein);
  • all food requiring processing should be boiled or steamed;
  • it is strongly recommended to grind food and dishes before eating to an almost homogeneous state.

Conservative treatment of nonspecific ulcerative colitis

Conservative therapy for nonspecific colitis is based on the principles of suppressing the inflammatory process with anti-inflammatory nonsteroidal drugs, hormonal agents (corticosteroids) and suppressing the body's immune autoreaction with immunosuppressants. These groups of drugs are used sequentially, in the presence of a good therapeutic response to anti-inflammatory drugs, additional medications are not connected to the course of treatment.
The main groups of drugs and features of their appointment:

  • 5-acetylsalicylic acid (long-acting acetylsalicylic acid with a long release period of the active substance, which allows exposure to the intestinal mucosa in the desired area of ​​​​the intestine. Such drugs include Pentasu, Mefalazim, Sulafalk, Sulafalazin, etc. The use of conventional acetylsalicylic acid ( Aspirin) is highly discouraged due to possible worsening of symptoms;
  • hormonal corticosteroids. They are used in short (up to 3-4 months) courses to achieve remission and reduce the severity of the disease. Corticosteroid drugs equally affect inflammatory processes throughout the body, affecting the mechanisms of tissue reaction. However, long-term use can cause multiple side effects. The most common include night sweats, increased hairiness of the skin, including in the facial area, sleep disturbances (insomnia), excitability, hyperactive state, decreased general immunity with increased susceptibility to the effects of pathogenic microorganisms. With a long course of therapy, it is possible to develop type 2 diabetes mellitus, hypertensive reaction (increased blood pressure), cataracts, osteoporosis and a tendency to injury due to impaired calcium absorption. With therapy in childhood, body growth may be slowed down. The appointment of a course of corticosteroid drugs is justified in persistent severe ulcerative colitis that does not respond to other types of treatment;
  • drugs that suppress the reaction of the immune system (immunosuppressants) affect the severity of the inflammatory process by reducing the autoimmune aggression of the body. The main effect - suppression of immune defenses - leads to increased susceptibility to infections, as a result of which drugs are prescribed in short courses and under close medical supervision. During therapy and for 2 months after it, it is recommended to refrain from contact with virus and bacterial carriers, avoid crowded places during the season of increased epidemiological danger.

Nonspecific ulcerative colitis (proctitis, proctosigmoiditis, colitis and other varieties) may require additional methods of conservative therapy in severe cases, severe symptoms (fever, severe pain, severe diarrhea, etc.). In such cases, specialists can add the following groups of drugs to the course of therapy:

  • group of antibiotics. With an extensive inflammatory process, accompanied by elevated body temperature and the growth of pathogenic bacterial flora, antibacterial drugs are selected in accordance with the patient's data (age, general condition, allergic reactions or individual intolerance, etc.). It is possible to use both intestinal antibiotics and antibacterial drugs with low absorption, and systemic drugs, depending on the severity of the condition;
  • antidiarrheal agents for nonspecific ulcerative colitis, even in the severe stage of the disease with severe diarrhea, are used only as directed by a doctor. The combination of the inflammatory process of the intestinal mucosa and fixing drugs can lead to acute toxic megacolon (expansion of the large intestine, loss of tone of the intestinal area), which, without emergency help, can lead to death. Loperamide and Imodium are considered first choice when antidiarrheals are needed;
  • painkillers are also selected by a specialist. The use of common non-steroidal anti-inflammatory drugs (ibuprofen, aspirin, etc.) may worsen the course of the disease due to an increased risk of side effects from the gastrointestinal tract;
  • to replenish iron deficiency and reduce the severity of iron deficiency anemia, which often accompanies the development of nonspecific ulcerative colitis due to blood loss, iron preparations are prescribed, both in mono- and in a multivitamin complex;
  • to maintain electrolyte balance, it is possible to take rehydration solutions, as well as potassium, magnesium preparations, etc.

With the development of diseases associated with ulcerative colitis, drug and supportive therapy is chosen taking into account the main diagnosis and the effect of drugs on the affected intestinal walls. Therapy, if possible, is recommended for a period of remission.

Surgical methods for the treatment of nonspecific ulcerative colitis

Nonspecific ulcerative colitis requires surgical treatment in the following cases:

  • with an acute, transient form of the disease with no therapeutic response to conservative therapy within 14-28 days;
  • with a subacute, recurrent, progressive form of UC with an unsuccessful result of drug therapy for six months;
  • in chronic colitis with a change of exacerbations and remissions and irreversible changes in the mucous membranes of the walls of the colon;
  • with severe, life-threatening complications, regardless of the stage of the disease.

Surgical treatment of UC may be required on an emergency basis, urgently and as a planned operation. Indications for emergency surgical therapy are intestinal perforation and peritonitis, as well as intestinal obstruction. If acute intestinal obstruction is not diagnosed, the operation can be transferred to the category of urgent or requiring clarification, however, intestinal perforation of any degree is an absolute indication for emergency intervention, since the mortality rate from perforation is up to 40% of the total number of patients with this pathology.

Urgent surgical intervention is performed in the diagnosis of profuse bleeding of the walls of the colon, abdominal abscesses, acute toxic dilatation (megacolon, expansion) of the colon.
Planned surgical methods of treatment are prescribed:

  • with a form of the disease resistant (resistant) to the drug treatment, hormone-dependent form, etc .;
  • with a disease duration of more than 10 years with an average or high degree of dysplasia of the epithelium of the intestinal walls;
  • at the onset of carcinogenic processes, the degeneration of mucosal tissues into tumor formations.

The total number of patients with UC undergoing surgical treatment is about 10%, of which about a quarter are patients with intestinal pancolitis.
Various methods of surgical treatment of NUC are conventionally divided into three main groups:

  • the first includes palliative intervention on the autonomic nervous system. This type of surgical treatment is recognized as ineffective with a short-term effect and is currently not recommended when choosing a method of therapy for ulcerative nonspecific colitis. This technique is not applicable to urgent and emergency operations;
  • ileostomy, colostomy and similar methods of operative surgery. It is carried out in the area above the place of registration of the destructive process in order to exclude the affected area of ​​the intestine from the digestive process. This type of palliative intervention in most cases is a preliminary, supportive stage before the next method of surgical therapy. However, in some patients, such operations followed by combined conservative treatment can lead to a long-term remission of the disease;
  • radical surgery is to remove the area or the entire colon affected by inflammatory changes.

An option such as appendicostomy, which was used earlier, is not recommended today in surgical practice for the treatment of UC and other inflammatory and destructive bowel pathologies (Crohn's disease, etc.).
Variants of segmental and subtotal resection (partial removal) of the colon are currently recognized as not quite effective methods due to the high risk of recurrence of the disease in the remaining area.

Coloproctectomy with the formation of an end ileostomy is considered the optimal technique. This type of surgical treatment is characterized by the lowest number of postoperative complications and the need for repeated surgical treatment. Also, with coloproctectomy, the formed ileostomy is easy to care for and access.

However, due to the peculiarities of the location of the ileostomy, patients more often prefer the colostomy version of the operation, in which dense fecal masses come out of the formed hole, and not the liquid contents of the small intestine, as with an ileostomy. However, the effectiveness of the ileostomy technique is much higher and allows us to talk about the possible recovery of the patient without radical intervention. Any type of hole after the patient's recovery can be eliminated.

Methods of washing the colon with antiseptic, antibacterial solutions through the hole formed during the operation rarely lead to the expected effect. It is worth remembering that after these types of palliative intervention, it is necessary to critically assess the condition, dividing the long-term remission and complete recovery of the mucosa. In case of an erroneous assessment, a second similar operation or a radical removal of the colon may be required.

Radical surgery, indicated for patients with a severe form of the disease, is often recommended to be carried out in two stages. At the first, an operation is performed with the imposition of an ileostomy hole, which improves the general condition of the patient when the colon is turned off from the process of digestion. After the recovery period, against the background of stabilization of appetite, sleep, body weight growth, improvement in protein and hemoglobin levels and a decrease in beriberi, as well as restoration of mental balance, radical surgical therapy is performed with the removal of the colon. On average, it takes from several months to six months to restore physical and mental stability, reactivity and resistance of the body. It is important not to stop at this stage if there are earlier indications for radical treatment.

Prevention methods

Since the exact causes of the development of the disease have not been identified, prevention methods include a healthy lifestyle, rational nutrition, timely elimination of symptoms and treatment of intestinal infections, correction of food allergic reactions, etc. Preventive, preventive measures are especially important in people with inflammatory bowel diseases family history.

A good result is the treatment of ulcerative colitis with folk remedies; the most effective of them can be suggested by the doctor after examination and confirmation of the diagnosis. Why does ulcerative colitis occur and how does it manifest itself? What methods of treatment of the disease exist, what herbs are suitable for treatment and how to use them correctly?

Doctors have not yet been able to determine the exact causes that lead to the development of ulcerative colitis of the intestine. But there are some directions that can provoke it.

These include:
  • diseases of the gastrointestinal tract;
  • hereditary predisposition;
  • environmental impact (polluted air, water, etc.);
  • infectious diseases;
  • disorders in the immune system;
  • psychological factors.

Ulcerative colitis of the intestine has a gradual development. At the initial stage, the rectum is affected. After that, the pathology spreads to the large intestine. In the end, ulcers appear on the mucous membranes. It is noted that the calmer the person, the lower the risk of this disease. It is believed that it is nervousness and constant stress that provoke its development. Therefore, the treatment of nonspecific ulcerative colitis should be carried out against the background of the restoration of the patient's psycho-emotional stability.

There are 3 stages of intestinal colitis:
  1. Acute or initial stage, in which the patient has the first symptoms of NUC (ulcerative colitis).
  2. Chronic.
  3. Recurrent, associated with periods of exacerbation of pathology.

The disease can manifest itself in different forms, which depend on the severity of the pathology:
  • mild, which is characterized by an increase in stool (in which blood streaks are clearly visible) less than 5 times a day;
  • medium - the frequency of loose stools is in the range of 5-8 times during the day;
  • severe - associated with a significant increase in loose stools (with impurities not only of blood, but also of pus) occurs at least 8 times during the day.

Treatment of ulcerative colitis should be aimed at restoring the intestinal mucosa damaged as a result of UC. With NUC, the use of medicinal herbs that have an enveloping effect and are able to relieve inflammation and heal ulcers is shown.

Medical treatments for ulcerative colitis may not work. In this case, many of the attending physicians often suggest that patients take traditional medicine. For this, herbal decoctions and infusions are used to help start the process of restoring the damaged mucous membrane.

Treatment with folk remedies also contributes to the replenishment of fluid, the loss of which is characteristic of the disease. What herbs can be used?


The most effective folk remedies for the treatment of ulcerative colitis are:
  1. Dried blueberries. Decoctions from it prevent the processes of decay in the intestines and serve as a preventive measure for the occurrence of oncological neoplasms.
  2. Decoctions of raspberry or strawberry leaves have a positive effect on the liver.
  3. A decoction of pharmacy chamomile has anti-inflammatory and antimicrobial effects, is able to eliminate spasms.
  4. Nettle decoction improves blood clotting, which helps prevent bleeding. This remedy has an anti-inflammatory effect and helps to free the intestines from pus.
  5. Peppermint decoctions and tinctures restore the patient's psycho-emotional state, relieve spasm and effectively fight pathogens.
  6. Yarrow is used to fight diarrhea and heal ulcers on the intestinal walls, a treatment that involves the use of a decoction based on the plant.
  7. To eliminate pain, relieve inflammation and restore damaged mucous membranes, grass can go down.
  8. To eliminate diarrhea and relieve inflammation of the intestinal mucosa, use the infusion of Potentilla.
  9. Infusions from dried pomegranate peel eliminate diarrhea and relieve the inflammatory process.
  10. Celandine helps to treat the disease at any stage of its development. The plant has antimicrobial, anti-inflammatory and wound healing effects. In addition, decoctions from it relieve anxiety and nervous tension. You need to start taking such a remedy with small doses, gradually increasing them.
  11. An infusion of wormwood helps to get rid of harmful microorganisms.
  12. St. John's wort is used to stimulate motility, relieve inflammation and get rid of pus.
  13. Highlander bird is an antispasmodic. In addition, decoctions from it relieve inflammation and heal ulcers.
  14. Alder gives a good astringent effect. Decoctions from it help to cope with bleeding.

In order for herbal treatment to give the best result, it is recommended to enrich the decoction or infusion with glycerin.


The use of microenemas is another method that provides the treatment of ulcerative colitis with folk remedies.

They can be done:
  • with sea buckthorn oil;
  • with rosehip oil;
  • with infusion of celandine.

Before starting the treatment of UC using microclysters, it is necessary to clean the intestines. To do this, you can use boiled cooled water, decoctions of chamomile or calendula.

The following methods help to cure NUC:
  1. Patients diagnosed with ulcerative colitis are advised to drink freshly squeezed juices daily. A good effect is given by combinations of spinach and carrots (the ingredients are taken in a ratio of 2:5) and cucumber, carrots, beets (the required proportion of vegetables is 3:10:3).
  2. One of the remedies often used by the sick is propolis tincture mixed with milk. For 250 ml of warm milk, you need to take 30 drops of tincture. The drug is taken three times a day 1 hour before meals.
  3. With ulcerative colitis, white clay can be used, from which a solution for drinking is prepared. For 100 ml of warm water, take 1 teaspoon of clay. Mix everything well and drink before eating.
  4. Raw, unpeeled potatoes are rubbed on a fine grater and mixed with fresh kefir. For 1 cup of kefir - 1 medium potato. The medicine is taken in the morning on an empty stomach 3 hours before meals.

Folk remedies have proven effective for the treatment of ulcerative colitis. But, before using them, it is necessary to consult with your doctor in order to avoid the development of complications and side effects.

Modern treatment of UC

NONSPECIFIC ULCERATIVE COLITIS

NUC is a necrotizing recurrent inflammation of the mucous membrane of the colon and rectum with their erosive and ulcerative lesions and frequent involvement of a number of other organs (joints, liver, skin, eyes) in the process. Proctitis is more common than total colitis, and depending on the severity and prevalence of nonspecific necrotizing inflammation, mild (mainly proctitis), moderate (mainly proctosigmoiditis) and severe (mainly total colitis) forms are distinguished; possible acute course of the disease. Epidemiology. NUC is a very common disease, in particular, in a number of countries in Western Europe and the United States. People of all age groups get sick, but more often young (30-40-year-olds). Among some nationalities, UC is especially common.

Thus, among Jews living in the United States, NUC occurs 4-5 times more often than among representatives of other nationalities.

The etiology is unknown. A putative genetic predisposition for the disease has been described in monozygotic twins. From the point of view of the clinician, the assumption of the viral nature of UC is most impressive, but evidence for this hypothesis has not yet been received.

Pathogenesis. UC is the result of environmental factors that, in people with a genetic predisposition, disrupt the regulatory mechanisms that inhibit immune responses to gut bacteria. Probably, the damaging agent (virus, toxin, microbe) stimulates the immune response, accompanied by the formation of autoantibodies against the intestinal epithelium. The small concordance for UC in monozygotic twins (6-14%), compared with twin concordance in Crohn's disease (44-50%), is the strongest evidence that local environmental factors are more important than genetic factors for the pathogenesis of UC.

Of all the environmental factors, smoking is the most surprising, which prevents the development of UC (and in Crohn's disease has a harmful effect). The relative risk of developing ulcerative colitis was 4.4, 2.5, 1.0, and 0.6 for those who had previously smoked heavily and then quit, as well as for all who quit smoking, for non-smokers and for smokers, respectively. the ingredient that contributes most to these patterns is nicotine, but the mechanism remains unclear.

Smoking has been shown to affect cellular and humoral immunity as well as increase mucus production in the colon; at the same time, smoking and nicotine inhibit colonic motility.

The long-standing view of UC as an autoimmune disease has recently received a new development due to the knowledge that the commensal microflora and its metabolic products serve as self-antigens, and that ulcerative colitis develops due to a loss of tolerance to substances of the normal intestinal flora, which are usually harmless. The most reproducible evidence of non-epithelial autoimmunity in ulcerative colitis includes: a high frequency (about 70%) of detection of pANCA in ulcerative colitis and an even higher prevalence of pANCA among patients with sclerosing cholangitis, with refractory left-sided ulcerative colitis, as well as the development of chronic inflammation of the bag-collection bag after the imposition of a small-intestinal-bursal anastomosis.

Less convincing is the view that pANCA is a marker of genetic susceptibility to ulcerative colitis.

Morphological changes. In UC, the entire mucosa appears ulcerated, hyperemic, and usually hemorrhagic ("bloody tears"). Endoscopy reveals a slight contact vulnerability of the mucosa. There may be blood and pus in the intestinal lumen. Inflammatory reactions are diffuse in nature, leaving no healthy intact areas. Pathological changes are never accompanied by thickening of the walls and narrowing of the intestinal lumen.

Classification of UC is usually divided by clinicians into acute (fulminant) and chronic forms.

The latter can be recurrent and continuously recurrent.

According to the localization of the process, distal forms are distinguished (proctitis and proctosigmoiditis); left-sided, when the process captures the overlying sections of the colon, and total forms, in which the entire colon is affected. The latter are the most severe.

In addition, a newly diagnosed chronic form of UC (primary chronic form) is distinguished, accompanied by an exacerbation every 2-4 months.

Clinic. The main manifestations of UC are bloody diarrhea and abdominal pain, often accompanied by fever and weight loss in more severe cases.

According to the severity of the course of NUC, light, moderate and severe forms are distinguished. With a mild course, the frequency of stools is not more than 4 times a day, it is either formed or mushy, with an admixture of blood, mucus. The general condition of such patients does not suffer. There is no fever, weight loss, no anemia and no damage to other organs and systems.

Endoscopy reveals contact bleeding of the mucous membrane, often pronounced edema and hyperemia.

With moderate severity, the stool is up to 8 times a day, not formed, with a significant admixture of mucus, blood and pus. There are pains in the abdomen, more often in the region of its left half. There is a febrile (up to 38 ° C) fever, weight loss up to 10 kg over the last 1.5-2 months, moderate anemia (up to 100 g/l), increased ESR (up to 30 mm/h).

Endoscopy reveals superficial ulcers, pseudopolyposis, severe contact bleeding of the mucous membrane.

In severe stools more than 10 times a day, scarlet blood or blood clots without feces can be released, sometimes bloody tissue detritus, mucus and pus are released in large quantities. There is severe intoxication, high fever (38.5-39°C), loss of more than 10 kg of body weight in less than a month, dehydration, convulsions. On examination: anemia (hemoglobin content below 100 g/l), leukocytosis more than (10-12)x10*9l, ESR - more than 40-50 mm/h, severe hypoproteinemia, hyper-y-globulinemia, changes in the spectrum of protein fractions.

At endoscopy - even more pronounced changes in the mucous membrane, there is a lot of blood and pus in the intestinal lumen, the number of ulcers increases.

With isolated proctitis, constipation is quite common, and painful tenesmus may be the main complaint.

Sometimes intestinal symptoms are in the background, and general symptoms prevail: fever, weight loss, and any of the extraintestinal symptoms.

There are 2 groups of complications: local and general. General (systemic) manifestations of NUC largely reflect the state of the body's immunological reactivity.

In the elderly, systemic manifestations are 2 times less common, and local manifestations are 2 times more common than in patients aged 20-40 years.

Local complications include bleeding, toxic dilatation of the colon, perforation, polyposis, swelling, strictures, fistulas. Physical findings are usually nonspecific: swelling or tension on palpation of one of the sections of the colon. In mild cases, there may be no objective findings at all. Extraintestinal manifestations include arthritis, skin changes, liver enlargement.

Fever, tachycardia, and postural hypotension usually accompany more severe cases.

Diagnosis. Mandatory laboratory tests. Complete blood count (if there is a deviation from the norm of the study, repeat 1 time in 10 days). Single dose: potassium, blood sodium; blood calcium, Rh factor, coprogram, feces for occult blood, histological examination of the biopsy specimen, cytological examination of the biopsy specimen, stool culture for bacterial flora, urinalysis. Twice (in case of pathological changes in the first study): blood cholesterol, total bilirubin and fractions, total protein and fractions, AST, AlAT, alkaline phosphatase, GGTP, serum iron. Additional laboratory tests: coagulogram, hematocrit, reticulocytes, serum immunoglobulins, HIV tests, blood for markers of hepatitis B and C.

Mandatory instrumental studies. Single: sigmoidoscopy with biopsy of the rectal mucosa.

Additional instrumental studies. They are carried out depending on the severity of the course of the underlying disease, its complications and concomitant diseases.

Once: ultrasound of the abdominal cavity and small pelvis, endoscopic retrograde cholangiopancreatography, radiography of the abdominal cavity. Mandatory consultations of specialists: surgeon, gynecologist.

Diagnostic criteria: 1) clinical findings (diarrhea of ​​the colonic type); 2) data of rectoscopy and colonoscopy (in mild forms of the disease, the intestinal mucosa is hyperemic, edematous, granulated, easily vulnerable; the network of blood vessels disappears; with moderate colitis, bleeding joins, areas covered with purulent exudate appear; in severe cases of colitis - ulcers, pseudopolyps , strictures; in the biopsy specimen of the colon, abundant cellular infiltration of the own layer of the mucous membrane and a decrease in the number of crypts are noted); 3) X-ray diagnostics - a decrease in colon haustration, niches and filling defects along the contour of the intestine, shortening of the intestine, narrowing of the lumen; this research method can exacerbate the process;

4) repeated negative bacteriological tests for dysentery. The course is chronic, relapsing.

Treatment. The diet is similar to that for Crohn's disease (see above). The goal of therapy for UC is to suppress inflammation, relieve symptoms of the disease, induce remission and prevent relapses.

The basis of drug therapy for NUC is 5-aminosalicylic acid preparations - sulfasalazine, mesalazine (5-ASA), corticosteroids, immunosuppressants.

Numerous clinical observations have shown that sulfasalazine, with its high efficiency, often gives side reactions (20-40%), which are caused by sulfapyridine, a carrier of 5-aminosalicylic acid, which is part of its structure. In the colon, sulfasalazine is cleaved by bacterial azoreductases to release mesalazine (5-ASA), which has a local anti-inflammatory effect.

Mesalazine inhibits the release of B4 leukotriene by blocking the lipoxygenase and cyclooxygenase pathways of arachidonic acid metabolism, inhibits the synthesis of active inflammatory mediators, especially B4 leukotriene, prostaglandins, and other leukotrienes.

Currently, various forms of 5-ASA have been synthesized without sulfapyridine with different mechanisms of release of the active substance in the intestine: salofalk, pentasa, mesacol, salozinal and other mesalazine tablets. Tablet preparations differ in the composition of the shell, their enteric coating, as well as the rate of its dissolution depending on the pH of the digestive tract.

These properties are achieved by creating an inert capsule for mesalazine, which provides a delayed release of the active substance, depending on the pH of the medium and the time elapsed from the moment the drug was taken and its transit through the intestines.

Eudragit L coated salofalk tablets begin to release mesalazine (25-30%) in the terminal ileum at pH > 6.0 and in the colon (70-75%). The release of mesalazine is slow.

Pentasa consists of microgranules of mesalazine with a diameter of 0.7-1 mm, covered with a semi-permeable ethylcellulose shell, decompose in the stomach into microgranules coated with microcrystalline cellulose. This structure of the tablet promotes a slow uniform flow of microgranules, starting from the duodenum throughout the intestine - 50% is released in the small intestine, 50% in the large intestine and does not depend on the pH of the medium (from 1.5 to 7.5).

Thus, compared with other preparations containing mesalazine, Pentasa has a longer effect of the active substance with a constant concentration of the drug in different parts of the digestive tract, therefore, Pentasa is more effective in small bowel CD, which should be taken into account in clinical practice.

During therapy with Pentasa, the severity of microbial contamination of the small intestine, diarrhea, as well as changes in the pH of the chyme do not affect the concentration of the drug in the gastrointestinal tract, the degree of absorption and the release rate of mesalazine.

It is important to ensure a sufficient concentration of mesalazan in the areas of inflammation, which manifests its activity in local contact with the intestinal mucosa in proportion to its adequate concentration in the intestinal lumen.

Salofalk, pentasu, mesacol, tidocol, salozinal and other 5-ASA preparations are prescribed at a dose of 3-4 g/day until clinical and endoscopic remission is achieved.

In the active phase of CD, higher doses of mesalazine are required - 4.8 g of pentas, salofalk, which is practically equivalent in effectiveness to glucocorticosteroids.

After the attack subsides, a long-term intake (1-2 years) of 1.5-2 g / day of the drug is considered a prerequisite for maintaining remission - anti-relapse therapy. Rectal forms of mesalazine (salofalk, pentas and other suppositories - 1 g) are more effective than enemas with hydrocortisone in the treatment of patients with UC in the form of proctitis, providing a longer effect of the active substance on the inflamed mucosa.

With left-sided colitis, a combination of mesalazine tablets with suppositories and enemas is possible.

In the absence of the effect of the use of 5-ASA, in severe forms of UC, as well as in the presence of extraintestinal complications, the appointment of GCS is indicated. Corticosteroids block phospholipase A2, preventing the formation of all its metabolites, inhibit the activity of numerous cytokines. The drug of choice is prednisolone. The average dose is 40-60 mg (1 mg per 1 kg of body weight per day), high doses of 70-100 mg / day or metipred. After relief of the main symptoms of a severe attack, the dose is reduced gradually, 10 mg every week. At a dose of 30-40 mg, Pentasa, Salofalk - 3 g / day are included in the treatment regimen. The powerful therapeutic effect of the use of steroids often causes serious side effects - glycemia, osteoporosis, increased blood pressure, etc. To limit the systemic activity of prednisolone, topical hormones are used - budesonide (budenofalk), which has a high affinity for glucocorticoid receptors and a minimal systemic effect, since it reaches total blood flow only in the amount of 15%. The optimal therapeutic dose of budesonide (budenofalk) is 9 mg/day.

In cases of steroid resistance and steroid dependence, azathioprine and 6-mer-captopurine (6-MP) are used as monotherapy or in combination with corticosteroids.

Azathioprine and its active metabolite act on lymphocytes and monocytes, exerting an immunosuppressive effect on the synthesis of inflammatory mediators. The dose of azathioprine is 2 mg / kg / day, improvement is noted no earlier than after 3-4 weeks, the duration of treatment is 4-6 months. It has side effects: nausea, vomiting, diarrhea, leukopenia, etc.

Progress in the study of the pathogenesis of UC contributes to the creation and implementation of a new drug, ifliximab, which affects the immune system and the inflammatory process.

Infliximab blocks tumor necrosis factor-alpha, inhibits granulomatous inflammation and can be used in the treatment of exacerbations of UC.

The need for surgical treatment arises with complications (fistulas, stenoses, perforations).

The prognosis is serious. Within 24 years, the mortality rate is 39%.

A severe form of the disease already during the first attack gives 30% mortality.

The occurrence of cancer in NUC depends on the prevalence and duration of colitis. A particularly high risk (30-40%) of developing cancer in cases of total bowel damage with a history of more than 10 years.

Materials: http://ruslekar.com/publ/sovremennye_metody_diagnostiki_i_lechenija_nekotorykh_zabolevanij/nonspecificheskij_jazvennyj_kolit/5-1-0-280

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Nonspecific ulcerative colitis. Phytotherapy - a powerful assistant in the fight against a serious illness

Nonspecific ulcerative colitis is a formidable, deadly disease in its fulminant form, fraught with serious complications in the chronic course of the inflammatory process. Affecting the lower intestine (the rectum and colon are more often inflamed), ulcerative colitis manifests itself as pain in the abdomen, bleeding. When inflammation covers large areas of the inner surface of the intestines, diarrhea occurs, often mixed with mucus, blood clots.

Dehydration, constant (often painful) urge to defecate, allergies to certain types of protein foods, refusal to eat, depressed mental state, depression of most body functions - these are just some of the main symptoms and characteristics of the patient's condition with chronic ulcerative colitis.

The causes of ulcerative colitis are not exactly defined by modern medicine. It has been established that the nature of the disease lies in the self-destructive action of the body. It is assumed that the appearance of ulcerative colitis is largely a consequence of the presence of a defect in the genes.

It is noted that ulcerative colitis is rare in residents of areas where olive oil is traditionally consumed. Since Provencal oil is inaccessible to most citizens of our country, domestic phytotherapeutists have found another way to supply the body with oleic acid (it is it, contained in abundance in unrefined olive oil, that prevents the occurrence of intestinal inflammation) in combination with astringents.

By proposing to eat small doses of sea buckthorn oil daily, and in case of symptoms of the disease, apply nightly microclysters (preferably after cleansing the intestines with infusions of chamomile or calendula, if there is a tendency to constipation) with sea buckthorn and rosehip oil, herbalists have achieved impressive results.

For a cleansing enema, 1-1.5 liters of infusion is required: brew 2 tablespoons of chamomile or calendula flowers with a liter of boiling water, leave for half an hour, strain. Use warm. For microclysters, 30-50 ml of warm oil is enough, which is injected into the rectum for 20-30 minutes before bedtime. Part of the oil will be absorbed by the walls of the intestines and will have its therapeutic effect, the rest will come out.

But what about those patients who have been diagnosed with ulcerative colitis for a long time, and diets and drug treatment give a temporary or even dubious effect? Of course, turn to proven folk remedies and herbal medicine recipes!

The direction of the phytotherapeutic "hit" in ulcerative colitis is anemia (a consequence of blood loss), lack of appetite, erosion and ulceration of the inner surface of the intestines, and a depressed psychological state. A complex task requires a comprehensive solution, therefore, in the treatment of ulcerative colitis, herbal preparations are used, consisting of herbal preparations of co-directional action.

As a rule, fees intended for the treatment of ulcerative colitis include medicinal herbs that give:

Enveloping effect (helps protect the affected tissue from the traumatic effects of digestive juices and food debris);

Astringent effect (vasoconstriction reduces bleeding of inflamed intestinal membranes, reduces exudation, slows down the rate of development of the lesion, minimizes the likelihood of infection with pathogenic bacterial flora);

Anti-inflammatory and anti-allergic effect (food allergies are a constant companion of ulcerative colitis);

Hemostatic action.

During the period of remission, fees are applied that increase the intensity of blood circulation in the mucous membranes (and thereby contribute to regenerative processes), activating wound healing.

Multivitamin teas and infusions should become an indispensable assistant to the patient: constant blood loss, limited nutrition often lead to a deficiency of substances necessary for the body.

The precious experience of folk medicine enriches the treasury of knowledge with information about the healing power of individual plants, gives recipes for the rational use of the healing power hidden in herbal preparations.

One of the most important recommendations developed by traditional medicine and allowing in some cases to completely get rid of the symptoms of the disease concerns Icelandic cetraria. It helps to restore the mucous membrane of the stomach, intestines, relieves inflammation, treats erosion. Used for diarrhea. You can drink cetraria for a long time without fear of side effects, because. it is non-toxic and does not irritate the stomach. Moss decoction: 1 tbsp. l. well-ground raw materials brew 0.5 liters of boiling water. Boil over low heat or in a water bath for 5 minutes, leave for 30 minutes, strain. Take the resulting decoction divided into 3 doses 30 minutes before meals.

Alder bark and alder cones (overwintered, collected before the beginning of the spring sap flow), dried and crushed, are used to make a decoction, or brewed as tea. Used with honey. A successful combination of alder and soothing herbs - valerian, motherwort: 3 tablespoons of alder bark or cones, 1 tablespoon of motherwort herb, 1 teaspoon of valerian roots, mix. To prepare the infusion, brew a tablespoon of the mixture with half a liter of boiling water, leave for an hour, strain. Drink 4-5 doses a day instead of regular tea.

It is useful to take an infusion of dried berries and leaves of raspberries and wild strawberries. By activating the liver, raspberries and strawberries increase the overall tone of the body, contribute to the accelerated removal of toxins, and intensify the healing process of affected areas.

A turpentine balm based on cedar resin will have a tangible benefit in ulcerative colitis. I recommend making a turpentine balm with extra virgin olive oil: 1 part oleoresin (resin) and 5 parts oil. Make a mixture by heating in a water bath until completely dissolved, strain through cheesecloth. Resin and the turpentine balm created on its basis perfectly heals the gastrointestinal tract, has a disinfectant effect, restores the intestinal microflora and pancreatic function, cleanses the liver. Inside, the balm is used in its pure form or diluted in a small amount of any vegetable oil (for diarrhea, it is better to take it without diluting it). Start taking 2 drops 3 times a day, before meals. Adding 2 drops daily, increase the dose to 15 and drink for a month. This is one course of treatment. After a month break, the course can be repeated.

Long-term intake of a collection consisting of equal parts of centaury, sage and chamomile gives a significant effect in the fight against secondary bacterial lesions of inflamed intestinal areas. To prepare the infusion, a teaspoon of a mixture of herbs should be brewed with a glass of boiling water. Infuse for half an hour, strain. Taking an infusion of a tablespoon every two hours for several weeks, you can achieve stabilization of the condition of inflamed tissues, reduce pain, and reduce the frequency of the urge to defecate.

A peppermint leaf brewed in the same way with boiling water brings noticeable relief to patients who have ulcerative colitis with severe soreness. Take the infusion should be half a glass to a glass half an hour before meals.

The tannins of the pomegranate may be useful as an astringent for patients with ulcerative colitis. For treatment, both dry fruit peels and fresh grains with fleshy partitions and peel are used. The decoction is prepared by boiling chopped pomegranate for half an hour (1 pomegranate cut into pieces per half liter of water). The infusion is taken a little twice a day.

It is difficult to overestimate the healing effect of common yarrow on patients with colitis. The preparation of a medicinal infusion of yarrow takes time: up to a day, the grass drenched in boiling water languishes in a tightly closed opaque bowl. After the infusion is evaporated by half, cooled, mixed with a small amount of alcohol and glycerin, thoroughly stirred and aged for some time. A composition of 30 drops is taken half an hour before meals.

Good results are obtained by infusion of bird cherry fruits, taken as an additional remedy for half a glass before meals (2-3 tablespoons of fruits per half liter of boiling water, leave for half an hour).

Help microclysters with infusion of celandine, done twice a day. Celandine effectively fights pathogenic intestinal microflora, clears mucus. To prepare the infusion, 1 teaspoon of chopped herbs must be brewed with a glass of boiling water, leave for 15 minutes, strain. For one microclyster, 50 ml of infusion is enough, which should be injected into the rectum for 150-20 minutes. However, this plant contains toxic substances, and its preparations must be taken strictly following the dosage.

Bitterness, concentrated in wormwood, gentian, yarrow, dandelion and other plants, causes the gastrointestinal tract of a patient with ulcerative colitis to secrete more digestive secretions. Such a measure contributes to the complete absorption of nutrients in the upper intestines, which improves the general condition of the patient and reduces the load on the distal intestines affected by the disease.

Another proven means of combating the manifestations of ulcerative colitis, suitable for use both during the period of exacerbation and during remission, is a collection composed in equal parts of the herb cudweed, tea rose petals, pharmacy chamomile flowers, calendula flowers, horsetail herb, dried agrimony, bitter wormwood, valerian roots, wheatgrass, rose hips, dill, St.

The healing effect of medicinal herbs of this collection applies to all manifestations of the disease. At the same time, the active substances of plants do not oppose each other (as often happens with thoughtless mixing of herbal remedies), but effectively interact with each other, helping the weakened body to cope with the disease.

However, even the most effective herbal preparations should be taken against the background of a demanding attitude to the patient's diet. Special diets, made up of easily digestible products that provide the body with a full range of nutrients, vitamins, micro- and macroelements, as well as a limited amount of fiber, will become a worthy assistant to the healing forces of nature concentrated in medicinal plants.

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How to treat ulcerative colitis with folk remedies - Answers from A to Z

Treatment of ulcerative colitis with herbs should be very careful. The fact is that even seemingly harmless plants can cause significant harm to the body. Therefore, before being treated with herbs, it is necessary to consult a doctor or inform him, in order to possibly adjust the drug treatment taking into account the intake of herbs.

Also note that phytotherapy alone is not enough. Complex therapy is needed, including both medicines and herbal remedies. It is not necessary to rely only on the power of herbs in this situation, since serious symptoms of ulcerative colitis are often stopped with the help of hormonal drugs, which have no analogues in the plant world.

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In the most severe case of ulcerative colitis, stools are observed up to 10 times a day, scarlet blood or blood clots without feces can be released, sometimes bloody tissue mass, mucus and pus are released in large quantities. Typical high temperature. The person quickly loses weight. He suffers from abdominal pain, tenesmus (painful false urge to defecate), fever, convulsions, dehydration, severe weakness, anemia.

If suspected, patients need to do biochemical tests. Also, in the diagnosis of the disease, endoscopic and radiological studies can be recommended.

Features of the treatment of ulcerative colitis

In therapy, therapeutic and surgical methods are used. However, surgery is life-threatening, because there is a threat of inflammation and complications.

Ulcerative colitis cannot be cured with drugs, but with their help you can:

7. Raw mashed apples have a good therapeutic effect on gout, obesity, liver and kidney diseases, chronic and acute colitis.

8. Mix the leaves of sage and wormwood in equal parts by weight. Pour 1 tbsp with a glass of boiling water. mixture, insist, wrapped, 30-40 minutes, drain. Take 1 tbsp. every 2 hours. Instead of tea, drink liquid rice water.

9. For chronic colitis accompanied by constipation, drink 2-3 glasses of fresh juice from raw pumpkin.

1. The healing property of potato juice for ulcerative colitis has long been known. In order to cook it, you need to take a few potatoes, peel them, grind, squeeze the juice in the amount of ½ cup. Drink half an hour before meals, every day. Normalizes the natural intestinal microflora, acidity, helps with gastritis, ulcers, including colitis.

Take 20 g of dry peels or 50 g of fresh pomegranate with seeds, simmer for 30 minutes, pour 1 glass of water, strain. Take 2 tablespoons 2 times a day. Helps with allergic colitis and enterocolitis.

Pour 100 g of common yarrow herb with 1.5 liters of boiling water, leave for 18 hours in a sealed container. Strain the infusion and boil until it evaporates to 0.75 liters. Add 1 tablespoon of alcohol and 1 tablespoon of glycerin, mix well. Take 30 drops 30 minutes before meals. The course of treatment for colitis is 1 month.

Pour 1 tablespoon of bird cherry fruits with 1 cup of boiling water, cook for 5 minutes over low heat, leave for 2 hours, strain. Drink 0.25 cups 2-3 times a day for colitis.

Attention! Fruit seeds cannot be kneaded, they contain a toxic substance.

Take 25 g of rhizomes of erect cinquefoil, 20 g of leaves and blueberries, 55 g of chamomile inflorescences. Infuse 1 teaspoon of the mixture for 6 hours in 1 glass of cold water, boil for 5-7 minutes, strain. Drink the whole infusion in small sips during the day with colitis.

Take equal amounts of gray alder earrings, rhizomes of erect cinquefoil, stinging nettle root. Take 50 g of the mixture, insist 10-12 hours in 1 liter of cold water, cook for 10-12 minutes and strain. Drink 1 glass of hot infusion on an empty stomach, the rest - during the day for 4 doses. Apply in chronic colitis.

Take equally a leaf of peppermint, chamomile inflorescences, rhizomes of Potentilla erect. Infuse 1 tablespoon of the mixture for 30 minutes in 1 cup of boiling water, strain. Take 1 glass 2-3 times a day for colitis.

Take equally a leaf of wormwood and a leaf of sage officinalis. Infuse 1 tablespoon of the mixture for 30 minutes in 1 cup of boiling water, strain. For colitis, take 1 tablespoon every 2 hours.

Take equal parts herbs of common oregano, herbs of shepherd's purse, herbs of highlander birds, herbs of motherwort five-lobed, herbs of common yarrow, herbs of St. John's wort, nettle leaves. Pour 2 tablespoons of the mixture overnight in a thermos with 2 cups of boiling water, strain. Drink 0.5 cup 3 times a day for chronic colitis.

Pour 1 teaspoon of chopped herb fumes officinalis with 1 cup of boiling water, leave for 5 hours, strain. Take 1-2 tablespoons 3 times a day 30 minutes before meals for ulcerative colitis.

Pour 1 tablespoon of rhizomes and roots of burnet officinalis with 1 cup of hot water, boil for 30 minutes, leave for 2 hours, strain. Take 1 tablespoon 5 times a day before meals for colitis.

Anti-inflammatory medicinal plants. calendula, calamus, meadowsweet, yarrow, chamomile, plantain, sage, elecampane, tricolor violet.

Antiallergic medicinal herbs. yarrow, succession, hawthorn, veronica, chamomile, nettle, sage.

Hemostatic medicinal plants. horsetail, yarrow, yasnotka, serpentine, shepherd's purse, viburnum bark, nettle, blackberry, mountain ash, burnet, St.

Also, herbs that improve blood clotting should participate in the infusions: St. These herbs are recommended to be added to other medicinal collections.

In all cases of treatment of NUC with folk remedies, enemas with sea buckthorn oil are very effective. It promotes cell regeneration and the fastest healing of wounds and sores. In a small pear, collect 50 ml of oil and enter into the rectum in the supine position. Sea buckthorn enemas are recommended to be done at night. And in the morning you need to take 1-2 tablespoons. oils inside and always on an empty stomach.

NUC and homeopathy

Although homeopathic methods are no longer new methods of treatment, sooner or later there is a desire to give oneself into the hands of a homeopathic doctor. In this case, you need to choose an experienced, proven and qualified doctor.

The treatment of UC with homeopathy depends on the individual characteristics of the patient, therefore, only a conversation with a homeopathic doctor takes a lot of time, up to several hours. Based on the described symptoms and other characteristics, the doctor will select an individual treatment. which can start from conventional herbal medicine, and end with massage or acupuncture.

A complex therapeutic effect in the chronic course of ulcerative colitis provides a collection of herbs from equal parts of oregano herb, chopped shepherd's purse, leaves of dioica nettle, knotweed, yarrow, St. John's wort. To prepare the infusion, a teaspoon of a mixture of herbs should be brewed with a glass of boiling water. Insist 20 minutes. Take the infusion three times a day for half a cup before meals.

Another proven means of combating the manifestations of ulcerative colitis, suitable for use both during the period of exacerbation and during remission, is the collection. composed in equal parts of herb cudweed, tea rose petals, chamomile flowers, calendula flowers, horsetail grass, dried agrimony, bitter wormwood, valerian roots, couch grass, rose hips, dill, herb St. John's wort, yarrow herb, midge, nettle leaves dioecious, crushed Jerusalem artichoke tubers.

The healing effect of medicinal herbs of this collection applies to all manifestations of the disease. At the same time, the active substances of plants do not oppose each other (as often happens with thoughtless mixing of herbal remedies), but effectively interact with each other, helping the weakened body to cope with the disease.

It is also necessary to brew flax seed, burnet. These medicines can be bought at a pharmacy. First, also during meals, you can take festal. The course of such treatment lasts about 7 months.

Beauty and health

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Ulcerative colitis and folk remedies

Ulcerative colitis is a disease of the colon. This disease affects the mucous membrane. There are two types of colitis - chronic and acute. In order to cure the disease, you will have to make a lot of effort. In traditional medicine, pharmacological drugs are used for therapy, with the help of which exacerbation is relieved. Despite this, it will not be superfluous to look for folk remedies for the treatment of ulcerative colitis.

To date, it is not possible to name reliable causes of the disease. The normal functioning of the colon can be disrupted by pathogens (salmonella, streptococcus and staphylococcus), which lead to stagnation of the intestinal contents; foci of infection in the gallbladder and other organs associated with the intestines.

In addition, normal work is disrupted as a result of the systematic use of hard-to-digest food, alcohol and chronic constipation. Other causes of ulcerative colitis include allergic reactions of the body to certain foods, frequent stress, and the use of antibiotics.

How to recognize the disease by symptoms?

Exacerbations can appear due to nervous and physical overstrain. In most cases, this disease is faced by women. Patients develop diarrhea, there is a discharge of blood with feces, pain in the abdomen. Some patients even find an admixture of pus in the feces. In ulcerative colitis, the state of health is disturbed, which is accompanied by apathy, fever up to 37.5 ° C, loss of appetite. As a rule, the disease is perennial, therefore, it requires constant therapy to maintain.

In acute colitis, bloating, cramping abdominal pain, diarrhea with mucus, elevated body temperature up to 38-39 ° C appear.

Chronic colitis occurs due to acute inflammation or in cases where there are foci of infection in the pancreas, as well as the gallbladder and other organs, in addition, the occurrence of chronic colitis can be caused by malnutrition, abuse of spicy foods and alcohol.

Chronic colitis can present with poor appetite, nausea, flatulence, and general malaise. Pain in the abdomen, as a rule, is cramping in nature, accompanied by a strong urge to defecate.

Proven recipes from folk remedies

In the article "Folk remedies for catarrhal colitis" we have already touched on the topic of this intestinal disease.

1.A decoction of alder cones. Cones are harvested in winter. To avoid the appearance of mold on alder cones, they must be thoroughly dried. A decoction of cones is prepared very simply.

Half a glass of well-dried cones is poured with 500 ml of water and boiled over low heat for about 10-15 minutes. The filtered broth should be diluted with boiling water (you can use apple juice) in equal proportions. A decoction is taken on an empty stomach in the morning and evening, after adding valerian infusion (12-15 drops) to it. The course of treatment is 4 months.

Ulcerative colitis is a dangerous disease that is accompanied by a violation of the stool, pain in the hypogastrium, the appearance of blood and pus in the feces. It is possible to make a diagnosis only with the help of laboratory tests and instrumental examination (colonoscopy), pathology also needs to be treated within the walls of a medical institution.

After restoring the normal function of the large intestine, it will not be superfluous to recall herbal medicine and proper nutrition. Eat more water, fiber, and fortified foods. You can also drink decoctions and infusions based on medicinal plants: chamomile, calendula, yarrow, marshmallow. They will not only relieve inflammation, but also help restore the intestinal mucosa.

2. With severe pain, potato juice is always available and effective. With it, you can normalize bowel function and metabolism, which contributes to recovery. You only need a few potatoes to make potato juice. Raw potatoes are carefully ground on a fine grater, then the juice must be squeezed out of it well. Usage: 100 g of potato juice daily before meals.

Did you know that an ulcer is not only in the stomach or intestines? Read the article "How to treat an esophageal ulcer with folk remedies".

3. Well helps with ulcerative colitis healing herbal collection of yarrow, sage and chamomile. To prepare it, you need to take a tablespoon of each ingredient and mix well, then pour 3 cups of boiling water and leave until cool. After that, strain well. 8 times a day you need to take a tablespoon of infusion. This tool can be used both for treatment and for preventive purposes.

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