Riboxin is a drug that, by improving tissue metabolism, has a wide range of applications. In particular, the drug has an antihypoxic effect, is effective in the treatment of arrhythmias, and stimulates tissue repair during ischemia. The active substance - inosine, is a substance related to the human body, since it is part of RNA.

How does it work?

In the pharmaceutical industry, inosine is considered the precursor of ATP, adenosine triphosphoric acid. This definition means that inosine is necessary for the synthesis of ATP, and without it, processes such as glucose metabolism and the so-called tissue respiration, saturation of cells of various tissues with oxygen, cannot adequately proceed in the body. Moreover, the condition of the tissues improves even if oxygen is not supplied for some reason.

The fact is that inosine activates substances in cells that are able to decompose glucose into carbon dioxide and water without oxygen or with a small amount of it. In addition, when glucose is broken down, additional energy is released. The tissues receive additional energy supply, this helps the internal organs to function normally.

Therefore, when Riboxin is used, patients experience a significant improvement in metabolism. The drug also improves the regeneration of cardiac tissues. This is important, for example, in rehabilitation after a myocardial infarction, as well as in the drug treatment of arrhythmias. Riboxin increases the force of contractions of the heart. This is an important parameter of the work of this body.

In pharmacies, this drug is sold under the brand name "Riboxin", although it is produced by various manufacturers. This popular remedy is prescribed for cardiovascular diseases, for example, to prevent thrombosis. And although this drug is used quite widely in adults, it is used less often in pediatrics, for example, if a child is undergoing radiation therapy for cancer.

Good tolerability and safety speak for its use in the treatment of children.

Indications

Usually, Riboxin is prescribed only from the age of 18, but according to individual indications and only as directed by a doctor, in some cases this drug is also used at an earlier age. However, children's age is not an absolute contraindication to taking the drug. So, in children over 12 years of age, the drug is used only after a thorough assessment of the benefit-risk ratio. In exceptional cases, Riboxin is used in children from 3 years old and even infants.

In the latter case, a liquid dosage form of the drug is used. The general formula for indications for use in young children and infants is the same: if the risk of developing the disease outweighs the potential harm from the drug.

Riboxin is prescribed to children only under medical supervision.

The drug is also often prescribed to pregnant and lactating women. During pregnancy, inosine helps to saturate the cells of the tissues of the mother and fetus with oxygen, which prevents their hypoxia, and also helps beneficial substances to better reach the tissues of the mother and child.

Sometimes a woman who took Riboxin during pregnancy, being sure of its safety, gives it to her child as a "vitamin". Doctors categorically do not recommend doing this.

The effect of inosine on the children's body has not been fully studied, therefore it is prescribed to babies only in exceptional cases, taking into account the clinical picture of the disease.

Contraindications and side effects

An absolute contraindication to taking Riboxin is individual intolerance to its constituent components. These are, for example, potato starch, cellulose derivatives, aluminum - it is included in the coloring pigment of the tablet shell. The tablet also contains sugar, which must be taken into account if the child has diabetes. The solution for injection also contains excipients.

You should not take this medicine if you have been diagnosed with kidney failure. In this condition, the kidneys partially or completely lose the function of urine production, and inosine is excreted from the body with it. With hyperuricemia - a high content of uric acid in the blood, Riboxin is also not prescribed. According to some studies, this disease occurs in 3% of children. Therefore, when taking Riboxin, a child needs to control the level of uric acid in the blood.

When taking the drug, a child may experience skin itching, as well as hyperemia of the skin, i.e., local redness caused by an increase in blood flow to this area.

Forms of release and dosage

Riboxin is available in the form of yellow tablets and red capsules of 200 and 300 mg and a two percent solution for injection in ampoules of 10 and 20 ml. In the form of tablets, the drug is taken orally, that is, through the mouth after eating.

From the age of 14, the dose of the drug is the same as for adults. Children over 12 years of age are usually prescribed 2-3 times a day with a small dose, and if the drug is well tolerated and side effects do not appear, the doctor gradually increases the dosage in accordance with the child's disease, his general condition, cut analysis parameters and other factors. The usual daily dose of the drug is 0.6-2.4 mg.

For children under 12 years of age, the daily dose of inosine is calculated according to body weight, based on the calculation of 10-20 mg per 1 kg of weight. This dose is usually divided into 2-3 doses. For young children and infants, tablets and capsules are difficult to swallow. Therefore, you can open the capsule, take out the required amount of white powder from it and make a solution out of it by mixing it with a small amount of water. However, this method is not encouraged by doctors, since it is very difficult to calculate exactly how much powder to give a child.

The solution for injection can be administered both intravenously - using a syringe or dropper, and intramuscularly. Intravenous administration provides a faster effect of the drug, therefore it is used in emergency cases and in a hospital setting. At home, it is easier for a child to give a pill, crushing it if necessary.

According to the doctor's prescription, children can take Riboxin for 4 to 12 weeks.

Tablets and capsules.

10, 20, 30, 40, 50 pcs. packaged.

Composition and active substance

Riboxin contains:

Active ingredient: inosine 200 mg.

pharmachologic effect

Riboxin is a derivative (nucleoside) of purine, a precursor of ATP adenosine tiphosphate. Refers to a group of drugs that stimulate metabolic processes. It has antihypoxic and antiarrhythmic effects. Increases the energy balance of the myocardium, improves coronary circulation, prevents the consequences of intraoperative renal ischemia. It is directly involved in the metabolism of glucose and contributes to the activation of metabolism in conditions of hypoxia and in the absence of ATP.
It activates the metabolism of pyruvic acid to ensure the normal process of tissue respiration, and also contributes to the activation of xanthine dehydrogenase. Stimulates the synthesis of nucleotides, enhances the activity of some enzymes of the Krebs cycle. Penetrating into the cells, it has a positive effect on metabolic processes in the myocardium - it increases the force of contractions of the heart and contributes to a more complete relaxation of the myocardium in diastole, resulting in an increase in stroke volume. The mechanism of antiarrhythmic action is not fully understood.
Reduces platelet aggregation, activates tissue regeneration (especially myocardium and gastrointestinal mucosa).

Pharmacokinetics

It is metabolized in the liver with the formation of glucuronic acid and its subsequent oxidation. A small amount is excreted in the urine.

What helps Riboxin: indications

Comprehensive treatment of myocardial infarction, coronary heart disease, cardiac arrhythmias caused by the use of cardiac glycosides, against the background of myocardial dystrophy after infectious diseases. Liver diseases (hepatitis, cirrhosis, fatty degeneration). Operations on an isolated kidney (as a means of pharmacological protection when blood circulation is turned off).

Contraindications

Hypersensitivity to the drug, gout, hyperuricemia, pregnancy, lactation, age up to 18 years (efficacy and safety have not been established). Use with caution in renal failure.

Riboxin during pregnancy and breastfeeding

The drug is contraindicated during pregnancy and lactation.

Riboxin: instructions for use

Inside, before eating. First, 0.2 g is prescribed 3-4 times a day, then within 2-3 days the dose is increased to 9.4 g 3-6 times a day. Course 1-3 months.

Side effects

Allergic reactions: skin itching, skin hyperemia (the drug should be discontinued). Rarely: an increase in the concentration of uric acid in the blood, exacerbation of gout (with prolonged use).

special instructions

During the period of treatment with Riboxin, the concentration of uric acid in the blood and urine should be monitored.
Information for patients with diabetes mellitus: 1 tablet of the drug corresponds to 0.00641 bread units.
Does not affect the ability to drive vehicles and control mechanisms that require increased concentration.

Compatibility with other drugs

Immunosuppressants (azathioprine, antilympholin, cyclosporine, thymodepressin, etc.) with simultaneous use reduce the effectiveness of Riboxin.

Overdose

No cases of overdose have been reported to date.

Storage conditions and shelf life

In a dry, dark place, at a temperature not exceeding 25 °C. Keep out of the reach of children.

"Riboxin" is a drug that can have a positive effect on the energy supply of body tissues and metabolism.

It normalizes the heart rhythm and coronary circulation, and also increases the energy balance of the myocardium. Participating in the metabolism of glucose, "Riboxin" stimulates metabolic processes in the absence of ATP. Due to the ability of the drug to reduce tissue hypoxia, women are often prescribed riboxin during pregnancy, reviews after taking which indicate its high efficiency.

Taking this remedy promotes active tissue regeneration, which is especially important for the myocardium and mucosa of the gastrointestinal tract. "Riboxin" also lowers platelet aggregation, which is an indicator that determines blood clotting.

"Riboxin" is poorly soluble in alcohol and absolutely insoluble in water. In its pure form, it is an odorless powder of white, slightly yellowish color.

Indications for use

Take the drug in various dosages for the treatment of many diseases. As part of the complex therapy of coronary heart disease, the drug "Riboxin" is prescribed, reviews of which indicate its effectiveness at absolutely any stage of this disease. In addition, the drug is indicated in the recovery period after a myocardial infarction suffered by the patient.

Riboxin also comes to the rescue in the treatment of cardiomyopathy and myocarditis. Instructions for use, reviews of doctors and patients suggest that the drug does an excellent job of normalizing the heart rhythm. Moreover, in the treatment of arrhythmia, which was caused by an overdose of other drugs, the greatest effect is achieved.

Another use of the drug was found in the treatment of patients with uroporphyria - a violation of metabolic processes in the body.

"Riboxin" can also be part of the complex therapy of a number of liver diseases, which include cirrhosis, hepatitis, and fatty degeneration. In addition, the drug is prescribed to patients with toxic damage to liver cells caused by exposure to the body of various factors associated with professional activities or with the intake of certain drugs.

Often, cancer patients undergoing radiation therapy are prescribed "Riboxin". Reviews of patients after taking the drug confirm its effect, which is to reduce adverse reactions during radiation therapy.

The tool is part of the complex therapy of diseases of the organs of vision, in particular open-angle glaucoma.

With excessive physical exertion, the drug "Riboxin" is also shown, reviews of which, and only positive ones, were left by a considerable number of athletes.

Contraindications

First of all, it should be understood that, even knowing for sure your diagnosis, it is not recommended to self-medicate with this drug. The appointment of "Riboxin" should be carried out only by a qualified doctor and on an individual basis.

The main contraindication to taking the drug is individual intolerance or hypersensitivity to the active ingredients that make up the composition.

The remedy is contraindicated in patients with impaired metabolism of purine bases and uric acid, as well as in patients with gout. The fact is that the drug can provoke an attack of gout, as well as cause various adverse reactions during treatment with chemotherapy drugs. Therefore, the use of the drug by patients undergoing chemotherapy should be under the strict supervision of the attending physician, while regularly checking the amount of uric acid in the patient's blood.

Adverse reactions

The most common side reaction of the body to treatment with "Riboxin" is allergic, which is manifested by slight itching and redness of the skin. After stopping the use of the drug, the allergy immediately disappears.

With a long course of treatment with Riboxin, as mentioned earlier, gout may develop in patients with impaired uric acid metabolism and kidney disease. In this case, it is necessary to stop taking the drug and conduct therapy to combat inflammatory processes in the joints.

Currently, studies question the benefit of long-term use of the drug. However, patients and doctors do not agree with this: experience speaks of the effectiveness of long-term use.

Any medication should be taken strictly according to the instructions and only after being prescribed by a doctor. Riboxin is no exception. Reviews of doctors and patients indicate that as a result of an overdose of the drug, a rash, redness and itching may appear, as well as increased heart rate, heaviness in the chest and other discomfort. But all these symptoms are not dangerous and instantly pass with a decrease in the concentration of the drug "Riboxin" in the blood. Indications for use, reviews of the drug and a serious attitude to treatment will only lead to a positive effect.

Method of application and dosage

"Riboxin" in tablets should be taken before eating. The daily dose in the first days of treatment is 0.6-0.8 g (1 tablet 3-4 times a day). In the following days, if there are no negative reactions of the body, the daily dose can be increased to 2.4 g. The duration of the course of treatment should be determined by the attending physician, sometimes the duration of admission is up to 3 months, depending on the disease. For example, patients with uroporphyria should take "Riboxin" for 4-12 weeks, 800 mg daily.

The drug is produced not only in tablets, but also in the form of a 2% solution for injection, the introduction of which is carried out intravenously. The solution can be administered either by jet (very slowly) or by drip (50-60 drops per minute). On the first day of treatment, a solution in an amount of 10 ml must be administered only once. Further, the dosage can be increased to 20 ml several times a day if no negative side reactions have been identified and the patient feels well.

In order to enter the required dose of "Riboxin" by drop method, it must be dissolved in glucose or sodium chloride 5% (volume - up to 250 ml). The duration of treatment is 1.5-2 weeks.

Indications for use during pregnancy

Being an antioxidant, antihypoxant and a good tool for improving metabolic processes in tissues, "Riboxin" is especially important during the period of gestation.

The drug can be prescribed to support cardiac activity during a period of increased stress. Often, a solution of "Riboxin" is administered to women directly during childbirth, since it is at this moment that the load on the heart is greatest. It is indicated for use in the presence of liver diseases and gastritis in a pregnant woman. Moreover, the drug is able to reduce unpleasant symptoms and normalize gastric secretion.

If fetal hypoxia is detected, "Riboxin" can also be prescribed during pregnancy. Reviews of the decrease in the degree of oxygen starvation of the fetus after taking the drug confirm its effectiveness in this regard.

In the absence of any adverse reactions, pregnant women are prescribed 1 tablet 3-4 times a day for one month.

Contraindications during pregnancy

During gestation, many women are prescribed the drug "Riboxin", reviews of which indicate the advisability of taking it in this period. However, some are confused that in the instructions for the drug you can often find information that it is contraindicated during pregnancy. But you should not be upset and scared, because the basis of contraindications is only the lack of clinical research in this area. In addition, today there is a lot of evidence of the successful use of "Riboxin" during pregnancy. The drug does not have a pathological effect on either the mother or the fetus, therefore, there is no reason to fear. The only contraindication may be exclusively individual intolerance to the components of the drug. But, despite the harmlessness of "Riboxin", one should not forget that only a doctor can prescribe a remedy.

"Riboxin" in bodybuilding

Not only for the purpose of treatment for various diseases, the drug is used. As a dietary supplement for athletes, "Riboxin" is used in bodybuilding. Reviews about the safety of the drug and its positive effect on the body allow it to be used by supporters of sports without doping.

Being a precursor of ATP, it activates the regenerative and oxidative processes, due to which the metabolism and energy supply of tissues are activated. In addition, oxygen saturation of tissues improves.

Bodybuilders use Riboxin to gain weight. Reviews of other athletes suggest that, using the drug, it is possible not only to build muscle mass, but also to maintain it.

The impact of the drug on the body of athletes

When using "Riboxin", an athlete's body has a complex effect:

• Energy processes in the body and metabolism are improved.
• The risk of hypoxia of organs and tissues is significantly reduced.
• At the cellular level, the ability to regenerate tissues increases.
• Improves tissue respiration and blood flow.
• Significantly improves the work of the heart muscle, thereby reducing the risk of myocardial ischemia.

Dosage of the drug during sports

Thanks to the use of the drug, the athlete is much easier given heavy physical exertion, in addition, he becomes stronger and more resilient. However, it is important to take responsibility for the dosage of a drug such as Riboxin. Instructions, reviews of doctors suggest that the athlete should start taking the drug with small doses, thereby checking the reaction of his body to this medicine. The first few days you need to take up to four tablets during the day before meals. In the absence of adverse reactions within three days, the daily dose can be gradually increased to 14 tablets. The duration of the course should not exceed three months, after which it is not recommended to take the drug for several months to give the body a rest.

Interaction with other drugs

The simultaneous use of "Riboxin" and cardiac glycosides can prevent the occurrence of malfunctions in the heart, as well as enhance the inotropic effect.

Use with "Heparin" enhances the effectiveness and duration of the effect of the latter.

Using the drug in the form of injections, one should remember about its incompatibility with alkaloids: as a result of their mixing, insoluble compounds are formed. It is not recommended to combine the solution for injection with other drugs: undesirable chemical interaction of the components with each other may occur.

The drug is also incompatible with vitamin B6: simultaneous use deactivates both compounds.

To activate and normalize metabolic processes in the heart muscle, as well as eliminate tissue hypoxia, Riboxin is prescribed.

To achieve the desired effect when using the drug, it is necessary to familiarize yourself in detail not only with the indications, but also with the side effects of Riboxin.

The drug is available in the form:

• red hard gelatin capsules with white powder inside;
• tablets of two types;
• solution for intravenous injection.

The main ingredient of Riboxin is inosine, a nucleoside, the chemical precursor of adenosine triphosphoric acid (ATP), which is a universal source of energy for all biochemical processes in the body.

Penetrating into the cell, the active component helps to increase their energy balance and stimulates the synthesis of nucleoside phosphates.

The production of Riboxin is carried out by numerous pharmaceutical enterprises in the territory of the post-Soviet space

Riboxin has the following effects:

• Anabolic. Promotes the formation and regeneration of damaged cardiac muscle tissue, as well as the gastrointestinal tract.
• Activates the Krebs cycle, which leads to improved respiration at the cellular level.
• Accelerates the microcirculation of biological fluids. It enhances capillary blood circulation and transport of blood and lymph, as a result of which the area of ​​necrotic changes in the myocardium during heart attacks becomes smaller, the risk of developing coronary disease is significantly reduced.
• It is a member of the energy exchange. The active component of Riboxin affects the metabolism and utilization of glucose - the main source of energy, which ensures the normal passage of any processes in the body.
• Improves metabolic processes with a lack of oxygen in tissues or individual organs.

The drug has the greatest effect on the myocardium and liver. Activation of metabolic processes in the organs leads to:

• increase the resistance of cells to hypoxia;
• restoration of the normal conduction of electrical impulses, as a result of which the heart rhythm normalizes;
• improving blood supply to the kidneys and heart muscle, as well as tissue respiration;
• reduce the risk of blood clots;
• decrease in platelet aggregation;
• increase in myocardial contractility;
• improving the recovery ability of the myocardium after heart attacks;
• prevention of chronic cardiovascular insufficiency and thromboembolism;
• restoration of the liver with pathological changes;
• better regeneration of stomach tissues in erosive and ulcerative lesions.

Riboxin does not apply to drugs with a pronounced effect, but in conjunction with other drugs, its use significantly improves the patient's condition.

Riboxin is used in conjunction with other drugs to combat:

Cardiovascular pathologies:

• ischemia of the heart;
• heart rhythm disturbances;
• intoxication caused by the use of cardiac glycosides;
• cardiomyopathies;
• consequences of myocardial infarction;
• angina;
• myocarditis caused by physical overload;
• congenital and acquired heart defects.

Pathological changes in the liver:

• hepatitis;
• fatty degeneration provoked by excessive alcohol or drugs;
• cirrhosis.

Urocoproporphyria.

Open-angle glaucoma with normal intraocular pressure by normalizing vision.

Ulcerative lesions of the stomach and duodenum.

Radiation burns. The drug promotes their speedy healing and does not allow a decrease in the number of leukocytes in the blood.

Riboxin enjoys good reviews from people involved in sports, especially power sports

A non-steroidal anabolic agent is taken by athletes in conjunction with steroids mainly in bodybuilding and powerlifting and leads to:

• increase the elasticity of the vascular walls;
• maintaining the level and throughput of hemoglobin;
• normalization of insulin synthesis;
• maintaining the heart muscle;
• stimulation of digestibility of carbohydrates.

The use of the drug does not affect the growth of strength and muscle mass. But it restores carbohydrate, protein and fat metabolism, leads to an increase in the protective properties of the body and an increase in the effectiveness of training.

Contraindications

Contraindications to the use of Riboxin can be absolute or relative.

The few contraindications and side effects, as well as the reasonable price of Riboxin, allow it to be used in almost all categories of patients.

So, if the injection solution is produced only on the basis of inosine (20 mg / l), then capsules and tablets are produced with the content of the active ingredient and:

• calcium stearate;
• potato starch;
• powdered sugar;
• a mixture covering a solid dosage form: Indigo carmine (E 132), titanium dioxide (E 171), Macrogol (polyethylene glycol 3000), iron oxide (E 172), Quinoline yellow (E 104).

Gouty arthritis

The main active component of Riboxin, inosine, is involved in the metabolism of purines, the destruction of which produces uric acid. This process is not anomalous.

However, high dosages of Riboxin, its use for a long time, mainly in the form of intravenous injections, provokes a significant rise in the level of uric acid and its deposition in various tissues of the body, especially in tendons and joints. This accumulation of the substance leads to a metabolic disease - gouty arthritis (gout).

Uncontrolled intake of Riboxin in rare cases provokes relapses or exacerbation of the disease.

Hyperuricemia

Hyperuricemia (elevated levels of uric acid in the blood plasma) is also a contraindication for taking Riboxin.

An excessive amount of a substance in the body when using the drug leads not only to the onset of attacks of gout, but also to kidney failure when uric acid crystals block the renal tubules.

The effect of Riboxin on the amount of uric acid makes it necessary to use it carefully and under the supervision of a doctor in case of kidney diseases or undergoing chemotherapy. The drug should be taken with regular checks of uric acid in the urine and blood of the patient.

Diabetes

There is an opinion that diabetes mellitus is a contraindication for the use of Riboxin. However, the instructions for use of the drug does not say anything about this.

On the one hand, eliminating tissue hypoxia, which is often observed in diabetics with hypoglycemia, the drug can only bring benefits. On the other hand, an increase in uric acid levels due to the use of Riboxin contributes to an increase in the body's resistance to insulin, which is highly undesirable.

In diabetes mellitus, any drug should be used under the supervision of specialists. Riboxin is no exception. Only after determining the ratio of benefits and harms from the drug can be included in the therapy.

Arterial pressure

Riboxin does not have a direct effect on blood pressure, and experts consider it inappropriate to use this drug to normalize its performance.

However, by improving the metabolic processes in the body, the drug indirectly leads to its decrease.

Hypotension is not an absolute contraindication to the use of the drug, but causes caution in its use.

Pregnancy and childhood age of the patient

Despite the lack of clinical studies on the effect of the drug on the body of lactating and pregnant women, the appointment of Riboxin during this period is often observed.

The tool is able to overcome the placental barrier, but its toxic effect on the body of the unborn child has not yet been identified. A drug:

• improves muscle formation of the fetus;
• eliminates fetal hypoxia;
• used to treat severe forms of placental insufficiency.

The use of the drug by expectant mothers may be due to an increased risk of ischemia and heart failure:

• obesity;
• antisocial lifestyle;
• insufficient or poor-quality nutrition;
• smoking or alcohol abuse, etc.

There is also no data on the penetration of Riboxin into breast milk and its effect on the baby's body.

The instructions for use of the drug prohibit its use until the patient reaches the age of 18 due to the lack of data on its efficacy and safety in childhood.

It is worth considering that Riboxin is incompatible with vitamin B6, acids, pyridoxine hydrochloride and alcohol.

Side effects

In rare cases, Riboxin leads to side effects that manifest themselves:

• allergic reactions in the form of rashes on the skin, hyperemia, itching;
• decrease in blood pressure;
• an increase in the concentration of uric acid in the body;
• rapid heartbeat;
• exacerbation of gouty arthritis;
• rapid heartbeat;
• dizziness and persistent headache;
• increased sweating;
• anaphylactic shock.

If side effects occur, the use of the drug should be discontinued.

When injecting the drug, local reactions in the form of redness and itching at the injection site are not excluded.

In order to avoid side effects of Riboxin, its use should be agreed with the attending physician.

The ability to have a positive therapeutic effect, harmlessness to the body, positive reviews and low price allow Riboxin to maintain popularity since the 70s. The drug is successfully used to treat heart disease, maintain the health of pregnant women, lose weight and in bodybuilding to form beautiful muscles.

Compound

The composition of the tablets includes:

• riboxin;
• calcium stearate;
• starch;
• methylcellulose;
• sucrose.

The tablets are coated with a coating consisting of indigo carmine, iron oxide, lactose monohydrate, titanium dioxide, macrogol, quinil yellow.
Injections contain inosine (20 mg/ml).
Inosine is the main active compound.

Release form

Riboxin is produced in the form of:

1. Double layer tablets. Biconvex tablets with a shell of yellow or yellow-orange shades have a rough surface. Under the shell is a white core. Tablets are sealed in blisters of 10 pieces. 1-5 blisters are placed in one pack.
2. Solution for injection (two percent). The volume of each ampoule is 10 ml. 10 ampoules are placed in a cardboard box.
3. Capsule. Packed in cardboard boxes of 20, 30 or 50 capsules.

pharmachologic effect

Riboxin is an effective anabolic that can saturate the body with oxygen and eliminate arrhythmia (restor heart rhythm).

It supports the metabolism of glucose and pyruvic acid, stimulates protein synthesis, normalizes tissue respiration, activates metabolism during oxygen starvation and ATP deficiency.

The medicine improves blood circulation. As a result, tissues are saturated with oxygen and receive proper nutrition. Metabolic processes are being established in them, energy supply is being restored. A person feels a surge of vitality.

The drug eliminates tissue hypoxia, which is important during pregnancy, when cells experience a constant lack of oxygen. In severe injuries that cause immobilization, Riboxin is administered intravenously. Nutrients are quickly transported through the blood stream to the cells of the non-moving parts of the body.

The drug will not allow platelets to stick together, form conglomerates. Prevents the formation of blood clots, improves blood clotting. At the same time, the quality of blood increases, the heart rate normalizes and stabilizes, tissue regeneration occurs (enhanced restoration of the mucous membranes of the gastrointestinal tract and myocardium).

The drug acts as an immunostimulant and nonspecific antiviral agent. It inhibits the development of pathogenic microorganisms. Fights measles, herpes, lymphoma and other pathogens of infectious diseases. In the body, under its action, lymphocytes are intensively produced, which kill pathological microorganisms.

Riboxin favorably affects the liver. The cells of the organ, having been saturated with oxygen, are actively restored. It is used in complex therapy for heart diseases.
The drug is recommended for athletes, bodybuilders. It nourishes muscle tissue, promotes effective muscle building.

Indications for use

The medicine is taken in complex therapy and as an independent remedy. It is used to treat serious pathologies of the heart, digestive organs, and liver. It is recommended in bodybuilding. The drug should not be taken without a doctor's prescription.

Riboxin is prescribed when the following pathologies are found:

1. Cirrhosis of the liver, hepatitis with damage and degeneration of tissue structures.
2. Ischemia. Riboxin is drunk at any stage of the disease and myocardial infarction.
3. Myocarditis and cardiomyopathy.
4. Arrhythmia (abnormal heart rhythm). Riboxin is especially effective for arrhythmias that have arisen against the background of drug and alcohol intoxication.
5. Myocardial dystrophy of various etiologies.
6. Ulcer disease.
7. Uroporphy (metabolic imbalance).
8. Fatty degeneration and toxic damage to liver tissues.
9. Eye diseases (for example, open-angle glaucoma).
10. Crayfish. The drug is prescribed after radiation, chemotherapy and surgery. It relieves side effects caused by radical methods of treating malignant tumors. Reduces the concentration of leukocytes after radiation therapy. Supports the body, alleviates the condition of cancer patients.
11. The transfer of inadequate physical activity in bodybuilding, which negatively affects the body. Riboxin relieves physical overstrain, replenishes energy, gives strength to the bodybuilder.

Contraindications

Riboxin is contraindicated in people with hypersensitivity to its components. An allergic reaction is expressed by reddening of the skin, itching. Allergy symptoms disappear as soon as the patient stops taking the medicine.

It is not prescribed for those who suffer from gout, who have an imbalance of uric acid and purines. Long-term use of the drug in people with kidney disease leads to the appearance of gout. If gout occurs, the medication is stopped. The patient is prescribed medications that relieve inflammation in the joints.

Treatment of patients undergoing chemotherapy is carried out under the strictest medical supervision. Doctors monitor blood tests, specify the concentration of uric acid in it. This avoids the occurrence of side effects (an attack of gout) from the use of potent drugs, the effect of which is enhanced by Riboxin.

Research scientists indicate that Riboxin is not suitable for long-term therapy. However, practitioners claim that long-term treatment with the drug allows you to achieve optimal results.

Side effects do not occur if the patient takes Riboxin, adhering to the doctor's instructions and recommendations (does not exceed the allowable dosage).

In case of an overdose, the skin begins to itch, a rash and redness appear on it. The patient has a feeling of heaviness in the chest, the heart beats hard. Such signs do not pose a serious danger to life. As soon as the concentration of inosine in the blood falls, the symptoms disappear.

Riboxin is not a harmless drug, self-medication is unacceptable to them. To prescribe the drug, the form of its administration (tablets, injections, capsules), dosage is the prerogative of a qualified doctor.

Side effects

Riboxin can provoke:

• in case of overdose, intoxication of the body and tachycardia, which quickly disappears after discontinuation of the drug;
• allergies (skin itching, urticaria);
• uric acid imbalance, gout attack;
• arterial hypertension;
• general weakness.

Instructions for use

Tablets are taken before meals. At the beginning of therapy, tablets are taken 1 piece 3-4 times a day. This scheme is used for 1-2 days. In the absence of side effects, the dosage is increased to 2.4 g per day (corresponding to 4 tablets). The course of treatment is determined by the doctor. It can last 1-4 months (depending on the individual characteristics of the body of a particular patient).

Patients with urocoproporphyria are prescribed no more than 0.8 g (200 mg per dose) of the drug per day for 1-3 months. The disease is characterized by an increase in the concentration of uric acid and its salts. Inosine increases the rate of urate metabolism, which leads to the formation and deposition of stones. Therefore, the prescribed dosage (1 tablet 4 times a day) is not exceeded.

Solution for injection is intended for intravenous administration. It is sprayed or dripped. A stream of fluid is slowly injected into a vein. On the first day, only one ampoule (10 ml) is used. If the patient does not experience adverse reactions, the dose is doubled (the solution is administered twice a day, 10 ml; or once a day the entire volume (20 ml) at once).

For drip administration, the drug is mixed with a glucose solution (5%) or sodium chloride (0.9%). The volume of liquid should be 250 ml. The solution is applied at 40-60 drops/min. The duration of treatment is 10-15 days.

Overdose

To avoid an overdose, Reboxin should be taken according to the scheme drawn up by doctors, or follow the recommendations given in the instructions. Increased doses lead to skin itching, redness of the epithelium, the appearance of rashes. They are able to provoke a failure of the heart rhythm, heaviness in the chest.

An overdose is not too dangerous for health. If symptoms of intoxication appear, stop taking the drug, consult a doctor.

Interaction

There are both drugs with which Riboxin is perfectly combined, and medicines incompatible with it:

1. Simultaneous intake of cardiac glycosides and Riboxin eliminates arrhythmia, increases the force of contraction of the heart muscle.
2. The drug increases the effectiveness of Heparin, increases the time of its impact on pathological foci.
3. Riboxin is compatible with furosemide, nitroglycerin, spironolactone, nifedipine.
4. Solution for injection must not be mixed with alkaloids. As a result of their interaction, insoluble compounds are formed.
5. Simultaneous intake of vitamin B6 and Riboxin is contraindicated. When drugs are combined, they are completely deactivated.
6. The solution for injection is diluted only in recommended solvents (glucose, sodium chloride). Otherwise, undesirable chemical reactions between substances occur in the solution.

Riboxin in bodybuilding

To achieve high results in bodybuilding, athletes often take approved drugs. Building muscle mass, pumping up muscles cannot be obtained without exhausting physical exercises.

To facilitate the formation of a beautiful body, bodybuilders drink harmless supplements. Thanks to bioadditives, athletes manage to maintain a crazy pace, get less tired.
Riboxin helps to form beautiful muscles without harm to the body. Taking it, bodybuilders quickly recover from the hardest strength training. They experience a surge of vitality.

Riboxin, once in the body of an athlete, enhances metabolism, activates biochemical and energy processes, promotes cell and tissue regeneration, and increases endurance.
The drug has a vasoconstrictive effect. Thanks to him, sprains and injuries occur less often. Under conditions of excessive force loads, the heart muscle has time to relax between contractions.

Riboxin is the most effective anabolic in bodybuilding among other non-steroidal and non-hormonal drugs. It is a great alternative to creatine, an unsafe and expensive supplement.

How to take Riboxin

Tablets are drunk 30-60 minutes before meals. Reception means begin with one tablet. If no adverse reactions occur within 1-2 days, the dosage is adjusted to 2.5 g per day.
The calculation for taking tablets is as follows: 0.15 g of the drug is used per 10 kg of weight of an athlete, bodybuilder. Drink tablets 1.5-2 hours before the start of strength training. Riboxin is taken in courses. Their duration is 1-4 months. Rest between courses should be at least 2-3 months.

Potassium orotate and Riboxin in bodybuilding

Bodybuilders often take Riboxin in tandem with Potassium Orotate, a safe drug. When used together, medicines achieve complete assimilation, give a stable result.

A single dose of bodybuilders - 2 tablets. This is quite enough to obtain optimal sports performance. Strength training after the joint use of drugs are effective.

Athletes feel uplifted. They increase their efficiency and increase their stamina. More tangible results are obtained by complex therapy: the simultaneous administration of Riboxin and Potassium Oratate with vitamins, adaptogens, and metabolic agents.

Asparkam and Riboxin in bodybuilding

Asparkam is a complex drug that is popular among those who are heavily losing weight and playing sports. It contains magnesium and potassium aspartate. Magnesium aspartate maintains protein balance, transports energy in the required volume. Potassium aspartate normalizes metabolism at the cellular level.

With strength training, Asparkam is a very useful supplement that relieves fatigue. An unexhausted bodybuilder trains more efficiently, easily withstands heavy loads.
When an athlete is in shape, he manages to achieve optimal performance. The feeling of strength allows you to build muscle mass, create beautiful reliefs on the body.

To avoid the accumulation of fluid in the tissues, Asparkam is drunk together with diuretics. At the same time, slags leave the body, and useful substances are retained.
Reception of Asparkam begins with 1-2 tablets 3 times a day. An increase in the dosage of the drug is performed according to the results of the tests and the general condition of the athlete involved in bodybuilding. For each bodybuilder, the course and regimen of taking Asparkam is strictly individual (they are compiled by a sports doctor).

Analogues

Preparations similar to Riboxin contain substances identical to inosine. They may contain Inosie-F, Riboxin Bufus, Ribonosin.

The analogues of the drug include:

• Piracetam;
• Enap;
• Panangin.

Panangin is close in effect to Riboxin. It nourishes the heart, improves its work. Normalizes the activity of the cardiovascular system.
The cost of Riboxin is low. The price of its analogues is even less. The cost of drugs does not exceed 100 rubles.