Terzhinan - instructions for use, reviews, analogs and formulations (vaginal suppositories or tablets) of a drug for the treatment of thrush (candidiasis), vaginitis and other infections, including during pregnancy and menstruation. Vaginal tablets (

It has anti-inflammatory and anti-allergic effect, suppresses exudation in the focus of inflammation.

Terzhinan has proven itself in the treatment of vaginal dysbacteriosis. Thanks to a well-thought-out combination of components, the drug is active against the most characteristic of the opportunistic microflora of the vagina and prevents the growth and reproduction of candida. The presence in the composition of prednisolone, a powerful anti-inflammatory agent, determines the effectiveness of the drug in bacterial or yeast vulvovaginitis. Associated infections are another specialization of Terzhinan. As a rule, in patients of a dermatovenereologist who applied for a specific infection, several more associated infections are detected. In such situations, it is not recommended to prescribe only systemic antibiotic therapy: drugs that have a local effect on the vaginal microflora are also needed. And Terzhinan comes in very handy with its anti-inflammatory and antibacterial properties. The drug is also used during preoperative preparation before cryodestruction, excision of the cervix, conization, cauterization of erosion - it is prescribed for 10 days before the upcoming procedure. This is done to suppress the inflammatory process accompanying the underlying disease in order to prevent morphological changes in the epithelium of the cervix and vaginal mucosa.

Pharmacology

Combined preparation for local use in gynecology. It has an antimicrobial, anti-inflammatory, antiprotozoal, antifungal effect; ensures the integrity of the vaginal mucosa and the constancy of pH.

Ternidazole - an antifungal agent from the group of imidazole derivatives, reduces the synthesis of ergosterol (an integral part of the cell membrane), changes the structure and properties of the cell membrane. It has a trichomonacid effect, it is also active against anaerobic bacteria, in particular Gardnerella spp.

Neomycin is a broad-spectrum antibiotic from the aminoglycoside group. It acts bactericidal against gram-positive (Staphylococcus, Streptococcus pneumoniae) and gram-negative (Escherichia coli, Shigella dysenteriae, Shigella flexneri, Shigella boydii, Shigella sonnei, Proteus spp.) microorganisms; inactive against Streptococcus spp. Microbial resistance develops slowly and to a small extent.

Nystatin is an antifungal antibiotic from the group of polyenes, highly effective against yeast-like fungi of the genus Candida, changes the permeability of cell membranes and slows down their growth.

Prednisolone is a dehydrated analogue of hydrocortisone, has a pronounced anti-inflammatory, anti-allergic, anti-exudative effect.

Pharmacokinetics

Data on the pharmacokinetics of the drug Terzhinan are not provided.

Release form

Vaginal tablets are light yellow in color, with possible inclusions of darker or lighter shades, flat, oblong in shape, with chamfered edges and printed in the form of the letter "T" on both sides.

Excipients: wheat starch - 264 mg, lactose monohydrate - q.s. up to 1.2 g, colloidal silicon dioxide - 6 mg, magnesium stearate - 10 mg, sodium carboxymethyl starch - 48 mg.

6 pcs. - strips (1) - packs of cardboard.
10 pieces. - strips (1) - packs of cardboard.

Dosage

For vaginal administration.

1 tablet is injected deep into the vagina in the supine position at bedtime. Before the introduction of the tablet should be held in water for 20-30 seconds. After the introduction, it is necessary to lie down for 10-15 minutes.

The average duration of the treatment course is 10 days; in case of confirmed mycosis, the duration of treatment can be increased up to 20 days; the average duration of the prophylactic course is 6 days.

Overdose

There are no data on cases of overdose.

Interaction

No drug interactions with Terzhinan have been identified.

Side effects

Local reactions: rarely - burning sensation, itching and irritation in the vagina (especially at the beginning of therapy).

Other: in some cases - allergic reactions.

These highly effective vaginal tablets are used for the treatment and prevention of inflammatory diseases of the female genital area. Tinidazole and neomycin, which are part of the drug, act on many pathogens, including difficult to eradicate Trichomonas, which makes it effective even with mixed infections. The nystatin contained in the tablets eliminates fungal colonies, prednisone - relieves swelling, itching and helps to extinguish the inflammatory process. In addition, Terzhinan vaginal tablets contain clove and geranium oils, which have an anti-inflammatory effect and help restore the vaginal mucosa. "Terzhinan" is compatible with hormonal drugs, for example, with Progestogel gel.

Side effects when using Terzhinan vaginal tablets are extremely rare, they usually occur within a few minutes after administration and appear as a burning sensation.

How to apply "Terzhinan"

Terzhinan vaginal tablets act exclusively locally, so patients do not have to worry about side effects associated with the penetration of drug components into the blood. It is quite simple to treat with this remedy, it is necessary to insert 1 tablet into the vagina for 10 days, to increase the effectiveness, hold it in water for half a minute. The use of the drug "Terzhinan" can be combined with physiotherapy.

Is it possible to use "Terzhinan" during menstruation

Unlike vaginal suppositories, tablets are not washed off by menstrual blood, even if menstruation is heavy. Menstruation is a natural provocation of the inflammatory process. In other words, during this period there is a “shake-up” of the woman’s body, as a result of which all latent infections appear. Thus, during this period, the drug will more effectively act on various infectious agents. Therefore, a delay in treatment due to menstruation is inappropriate in this case. Whether to take vaginal medicines during menstruation, a woman should decide directly with her doctor. The instructions for Terzhinan clearly state that treatment should not be interrupted for the period of menstruation.

Terzhinan is a drug developed for topical use in gynecology. It has an antifungal, antibacterial, anti-inflammatory effect.

Instructions for use Terzhinan

Terzhinan is available as vaginal tablets. One tablet contains 200 mg of ternidazole, 100 mg of neomycin sulfate, 100,000 units of nystatin, 3 mg of prednisolone. Ternidazole is an antifungal agent active against anaerobic bacteria. Neomycin is a broad spectrum antibiotic effective against streptococci, shigella and other bacteria. The resistance of microorganisms to this substance develops to a small extent and very slowly. Nystatin is an antifungal antibiotic that is highly effective against yeast-like fungi of the genus Candida. Prednisolone is an analogue of hydrocortisone, it has anti-inflammatory and anti-allergic effects.

Terzhinan is prescribed for the treatment of vaginitis caused by certain microorganisms. In particular, it is used for bacterial vaginitis, vaginal trichomoniasis, for vaginitis caused by fungi of the genus Candida, as well as for mixed vaginitis. The drug is used as a prophylaxis of urogenital infections or vaginitis before gynecological operations, before and after the installation of intrauterine devices, before childbirth or abortion, before intrauterine examinations.

Terzhinan is administered at bedtime. Before the introduction, the tablet must be put in water for 20-30 seconds, then it must be inserted deep into the vagina in the supine position. After that, you need to lie down for at least 10-15 minutes. The duration of the course of treatment is 10 days. If mycosis is diagnosed, the duration of treatment is increased to 20 days.

The prophylactic course of treatment should last 6 days.

Contraindications, side effects of Terzhinan

The use of Terzhinan is possible from the II trimester of pregnancy, in the I trimester of pregnancy and during lactation, Terzhinan is used only in cases where the benefit of therapy for the mother outweighs the risk to the child. During treatment with the drug, local reactions may occur - itching, burning sensation, irritation in the vagina, in some cases allergic reactions may occur.

Terzhinan must be stored at a temperature not exceeding 25 ° C, out of the reach of children. The shelf life of the drug is 3 years.

Cases of drug overdose have not been identified. Terzhinan should not be used in case of hypersensitivity to the components of the drug. In the case of diagnoses of vaginitis, trichomoniasis, treatment of both sexual partners is recommended. Men are prescribed a medicinal ointment or cream with a similar effect. During menstruation, treatment with Terzhinan should not be stopped.

The hormonal drug "Progestogel" is intended for the treatment of mastopathy. It contains progesterone, which inhibits the action of estrogen, which leads to a decrease in the compression of the milk ducts and a decrease in milk production.

Instruction

The drug "Progestogel" is produced in the form of a gel. It is prescribed for diffuse fibrocystic mastopathy and mastodynia, including those that developed during puberty, due to oral contraceptives, during premenopause, due to premenstrual tension. The drug reduces capillary permeability, reduces swelling of breast tissue. Topical application of the drug avoids the systemic effects of progesterone on the body and the appearance of negative side effects. The mechanism of action of the active substance is based on an increase in the concentration of progesterone in the mammary gland. Progesterone limits the effect of estrogens on breast tissue, has a slight natriidiuretic effect, preventing fluid retention and the development of pain.

"Progestogel" is applied to the chest once or twice a day using a dispenser-applicator. Do not rub the gel into the skin. After applying the drug, avoid exposure to direct sunlight. One dose of the drug is 2.5 g, it contains 0.025 g of progesterone. The gel is used daily or in the second phase of the cycle - from the sixteenth to the twenty-fifth day. Treatment of mastodynia or mastopathy lasts no longer than three cycles. A second course of therapy can be carried out only after consulting a doctor.

The drug is contraindicated in nodular forms of fibrocystic mastopathy, genital and breast cancer, in the second or third trimesters of pregnancy, with increased sensitivity to the components of the drug. With caution, the agent is used for liver failure, bronchial asthma, migraine, depression, epilepsy, renal and hepatic insufficiency, phlebitis, thrombosis, thromboembolic diseases, diabetes mellitus, hypertension. The appointment of "Progestogel" during periods of pregnancy and lactation is possible only if the intended benefit to the mother is greater than the potential risk to the child.

"Progestogel" has the following side effects: chest pain, "hot flashes", intermenstrual bleeding, nausea, fever, headache, decreased libido, redness at the site of application, swelling of the lips or neck. The action of the gel is enhanced when it is combined with combined contraceptives. "Progestogel" is stored at a temperature not exceeding 25 ° C. The shelf life of the drug is three years.

Candles "Terzhinan" are a combined preparation with bactericidal, antibacterial and antifungal properties. It is prescribed for local use in gynecology.

Instruction

The drug is recommended for use during bacterial and mixed vaginitis, vaginal trichomoniasis, vaginitis caused by Candida fungi. Also, "Terzhinan" is used before gynecological operations, before and after the installation of an intrauterine device, before abortion and childbirth, hysterography, before and after diathermocoagulation of the cervix. Candles are contraindicated in patients who are hypersensitive to the components of the drug.

The drug "Terzhinan" is available for vaginal administration. Each suppository must be moistened with water for 20 seconds before insertion and then inserted deeply into the vagina in the supine position. After the procedure, you need to lie down for 15-20 minutes. It is better to put candles before going to bed. Treatment should last at least 10 days. With complex mycoses, therapy is extended up to 20 days. Treatment continues during the next menstruation. The daily dosage of the drug should be agreed with the attending physician.

Side effects from the use of "Terzhinan" are rare and are expressed by allergic reactions. There may be a burning sensation when the candle is inserted. In such cases, the use of the drug should be discontinued and replaced with a more gentle analogue. The components of the drug in small quantities enter the general circulation, so the possibility of an overdose is unlikely.

Gynecologists often recommend Terzhinan to pregnant patients, since this remedy causes less health concerns. Its components do not accumulate in the body and do not harm the unborn child. In Russia, the drug is prescribed from the second trimester of pregnancy, and abroad it is used throughout the entire period.

Both sexual partners must be treated. Otherwise, re-infection is possible. Reviews of patients who used the drug are very diverse. One category of patients was satisfied with the treatment and received a quick positive result. Other patients did not experience improvement from the course of treatment. Also, some had to face an exacerbation of side effects and stop using the drug.

"Terzhinan" does not affect the ability to drive a car and other vehicles. Also, taking this drug does not affect classes and increased activity. Candles are freely dispensed from pharmacies. Should be stored in the refrigerator. The drug is produced by the French company Bouchard-Recordati Laboratories.

Sources:

The drug "Terzhinan" in 2017

The drug "Terzhinan" is a highly effective external agent for the treatment of vaginitis of various origins. It is also prescribed as a prophylactic before medical and diagnostic procedures. It contains a small amount of prednisolone, which greatly alleviates the condition with colpitis after the first application.

Instruction

After purchasing "Terzhinan" in a pharmacy, put it in a dark, cool place, but not in the refrigerator. At temperatures above 25 ° C, the active substances are destroyed. It is optimal for the period of treatment to put the package in the bedside table.

Take a shower or wash, but don't douche, wash your hands and get ready for bed. Tablets "Terzhinan", like any means of vaginal use, are used only at bedtime. That is, for several hours you need to occupy a horizontal position - otherwise the tablet will leak out.

Prepare a small bowl of water, lie on your back, remove your underwear. Remove the tablet from the individual package and lower it for 15-30 seconds. into the water and then insert it into the vagina as deeply as possible. Wipe your hands with sanitary napkins. To simplify the task, you can put a pillow under the lower back and hips. It is not recommended to administer a dry tablet - this reduces the effectiveness of the drug and may cause discomfort.

Put on your underwear, attaching a panty liner for daily use. Lie down to sleep or try to be in a horizontal position for at least 4 hours. A panty liner will keep you from spilling the tablet on your underwear. In the morning, the discharge from the vagina may intensify ─ this is the remnants of the remedy coming out. It is recommended not to take a shower for at least the first half hour after waking up - this is enough for all the remaining tablet to leave the vagina. After that, take a shower or wash yourself, but do not douche and you can go about your normal activities.

The course of treatment is 10 days, sometimes the course of treatment can be increased up to 20 days. At the first signs of relief, treatment should not be stopped, as microorganisms may become immune and subsequent treatment will require more serious drugs.

For the period of treatment, sexual activity, visiting pools and saunas, swimming in open water, drinking alcohol is prohibited. If an infection is detected, then the sexual partner must also be treated, even if he does not have characteristic symptoms.

If during treatment menstruation occurs, it is not required to stop it. Inject Terijinan into your vagina as you normally would, with tissues handy to dry your hands. Avoid tampons and switch to sanitary pads.

"Terzhinan" is used as a prophylactic before obstetric and surgical procedures. Usually, on the day preceding the manipulation, the patient is prescribed a single injection of "Terzhinan" into the vagina. In some cases, longer preparation may be required ─ the doctor will warn about this in advance.

A few days after the course of treatment, and if necessary, during the course of treatment, smears are taken. Do not use "Terzhinan" before a visit to a gynecologist or venereologist ─ this complicates the diagnosis, short-term sanitation of the vagina does not give the desired therapeutic effect, the result of a laboratory test may be false.

note

"Terzhinan" during pregnancy is used only in the second and third trimesters, in the early stages the drug can be potentially dangerous to the fetus.

"Terzhinan" is available in only one form of release ─ in vaginal tablets, they are often confused with suppositories. That is, speaking of candles "Terzhinan", they mean tablets. The pharmacist at the pharmacy will correct you and give you the right medicine. Assign "Terzhinan" for infections of the genital tract or as a sanitizing agent before and after medical manipulations.

Instruction

Put the purchased drug in a dry, dark place near the bed. It is not recommended to store the drug in the refrigerator. The optimum storage temperature is 25°C; at a higher temperature, Terzhinan loses its properties. Shelf life - no more than 3 years from the date of manufacture.

Apply the medicine in the evening before going to bed. You should wash yourself or take a hygienic shower, prepare a bowl of water, panty liners and sanitary napkins. If it is not possible to take a shower, use wipes for intimate hygiene.

Lie on your back, put a roller or pillow under your back (this will make it easier to insert the pill). Remove the tablet from the blister and dip it in water for half a minute. Gently insert the tablet into the vagina as deeply as possible. A tablet inserted shallowly will not have the desired therapeutic effect.

"Terzhinan" is a combination drug intended exclusively for local use for the treatment of gynecological diseases. The effectiveness of this drug is achieved through the action of special components that make up Terzhinan. In addition, such a drug has anti-inflammatory, antibacterial and antiprotozoal properties.

In the event that a woman is scheduled for surgical intervention, then the use of "Terzhinan" is based on the prevention of infectious complications immediately in the postoperative period. To do this, a six-day course of therapeutic therapy with such a drug is prescribed, which must be completed three days before the upcoming operation. For preventive purposes, the use of the drug "Terzhinan" is advisable before hysteroscopy, medical procedures on the cervix, labor or abortion.

"Terzhinan" in the form of vaginal tablets should be used by introducing them into the vagina, moistened with water in advance. For best results, lie down in a calm state for about ten minutes. It is recommended to use "Terzhinan" no more than one tablet per day. As a rule, the duration of treatment therapy is ten days. However, in the presence of fungal diseases, the duration of treatment can increase up to twenty days. It must be remembered that the interval between courses of therapeutic therapy with "Terzhinan" should be at least six months. This is due to the fact that microorganisms are able to adapt to the active components of this remedy, as a result of which the treatment will be ineffective. It is noteworthy that menstruation is not a reason to stop treatment with Terzhinan. In order to avoid re-infection with the infection, it is advisable to conduct an examination and treatment of a permanent sexual partner.

It is allowed to use "Terzhinan" during pregnancy only according to the strict indications of a doctor. After all, only he can correctly assess the possible danger to the fetus and give appropriate recommendations for therapeutic therapy.

Instructions for use of the drug "Terzhinan"

It should be noted that this medication is available in the form of vaginal tablets and is used only for local therapeutic therapy. The main indication for the use of "Terzhinan" are local inflammatory diseases caused by protozoal infection or anaerobic bacterial species. The main factor in successful treatment is a significant reduction in the severity of symptoms. In addition, a positive result of therapy directly depends on the implementation of a preliminary bacteriological diagnosis of vaginal discharge. In the event that a woman is scheduled for surgical intervention, the use of Terzhinan is based on the prevention of infectious complications immediately in the postoperative period. To do this, a six-day course of therapeutic therapy with such a drug is prescribed, which must be completed three days before the upcoming operation. For preventive purposes, the use of the drug "Terzhinan" is advisable before hysteroscopy, medical procedures on the cervix, labor or abortion. "Terzhinan" in the form of vaginal tablets should be used by introducing them into the vagina, moistened with water in advance. For best results, lie down in a calm state for about ten minutes. It is recommended to use "Terzhinan" no more than one tablet per day. As a rule, the duration of treatment therapy is ten days. However, in the presence of fungal diseases, the duration of treatment can increase up to twenty days. It must be remembered that the interval between courses of therapeutic therapy with "Terzhinan" should be at least six months. This is due to the fact that microorganisms are able to adapt to the active components of this remedy, as a result of which the treatment will be ineffective. It is noteworthy that menstruation is not a reason to stop treatment with Terzhinan. In order to avoid re-infection with the infection, it is advisable to conduct an examination and treatment of a permanent sexual partner.

Side effects of the drug "Terzhinan"

In general, this drug is well tolerated by patients. However, allergic reactions caused by intolerance to certain components can occur. In addition, after the introduction of the tablet into the vagina, there may be a pronounced burning sensation, itching, as well as redness of the genital mucosa. With the development of such symptoms, it is necessary to stop the use of the drug. It is allowed to use "Terzhinan" during pregnancy only according to the strict indications of a doctor. After all, only he can correctly assess the possible danger to the fetus and give appropriate recommendations for therapeutic therapy.

There are many good medicines in the world, but the vast majority of them have more or less pronounced restrictions for taking, contraindications, and side effects. To the greatest extent, this applies to the means used inside. But local preparations are not without drawbacks - for example, among candles for the treatment of inflammatory processes in gynecology, it is not easy to choose a medicine that can be advised in almost all cases without fear of consequences. Terzhinan, which doctors often prescribe to their patients, meets the highest reliability criteria. Why is he so good?

The action of terzhinan

Terzhinan vaginal tablets, produced by the French pharmaceutical company Laboratoires Bouchara-Recordati, contain several antimicrobial components.

Tinidazole affects the so-called anaerobes - bacteria that live in anoxic conditions. This substance copes with many pathogens, including difficult to eradicate Trichomonas, for the sake of getting rid of which earlier patients were supposed to drink unsafe metronidazole.

The next antibacterial agent, neomycin, covers the remaining spectrum of pathogenic bacteria, which makes the drug effective for any non-specific cause of infection, including infection with mixed flora.

Eliminates colonies of fungi, prednisolone suppresses inflammation, relieves swelling and itching. Also, the product is supplemented with clove and geranium oils, which have an antiseptic and anti-inflammatory effect, and also have a restorative effect on the mucous membrane.

When and how to apply the medicine

The drug is effective:

- with vulvovaginitis, vaginitis and colpitis of non-specific origin, including those that appeared after an exacerbation of genitourinary infections;

- to prevent infection before operations, childbirth, medical procedures (cauterization of the neck, setting the intrauterine device).

Evaluating the results of using the drug from a medical point of view, we can say that terzhinan is really effective both as a means of prevention and as a drug for the treatment of inflammation. Most patients describe its action as good, excellent, or nothing more, nothing less, excellent. Of course, it is also captivating that there are practically no prohibitions on the use of terzhinan: the drug acts exclusively locally, so patients may not be afraid of side effects associated with the penetration of its components into the blood.

It is very simple to treat with this remedy, you need to inject 1 tablet into the vagina every night for 10 days (as prescribed by the doctor - longer) every night. Before this procedure, the tablet should be held in water for half a minute so that it becomes softer and can dissolve, and after it you should lie down for several minutes.

Terzhinan during pregnancy

This remedy causes women much less concern than or even completely safe. Among a fairly large selection, it is often preferred to everyone else. And rightly so: the drug has something to “please” patients who have reason to fear for their own and not only their health.

So, the benefits of terzhinan for pregnant women are as follows:

- it does not accumulate in the body and does not cause effects on the child. Having established its low absorption, scientists were even “too lazy” to conduct pharmacokinetic studies, that is, to study its chemical transformations inside the body: it was not possible to find significant traces of the drug in the blood.

- its efficiency is close to 100%. Some women have difficulty choosing a remedy for "difficult" germs such as Trichomonas. But terzhinan works on the widest possible spectrum. Its component tinidazole, a safe “relative” of the dangerous metronidazole, significantly expands the range of therapeutic action of the drug, but it does not penetrate the mother’s body and does not pass through the placenta to the child.

- In the West, studies have been conducted that study the tolerability and effect of the drug in pregnant women at different times. In 2004, similar tests were carried out in our country, and twice as many patients participated in them than in Europe. Based on our results, it was included in the national guidelines for the treatment of urinary tract infections in pregnant women. Focusing on maximum safety, in Russia it is advised to use it from the second trimester - which is unusual, given that abroad it is used throughout the entire period.

The most frequent questions of patients

When using the drug the next day, a slight burning sensation appeared. How to evaluate it?

In rare cases, transient discomfort may occur at the beginning of treatment with terzhinan. It will disappear in 2-3 days.

The course is scheduled for 10 days, but in its second half, menstruation should begin. Should I stop treatment?

Not worth it, you need to continue therapy for the required time.

Along with inflammation, the doctor found erosion and prescribed local treatment for it. Is it possible to use terzhinan together with sea buckthorn suppositories?

It is possible, the components of terzhinan do not interact with other drugs. But, if possible, it is desirable to divide the use of different means by 1-2 hours.

After treatment with terzhinan, there was a delay in menstruation. Is it somehow related to the drug?

Terzhinan does not contain hormonal components, so it cannot affect the menstrual cycle, you need to look for other causes of the violation.

There was vulvovaginitis, a course of treatment with terzhinan was carried out. The drug helped, but after a short time the symptoms reappeared. And this is not the first time ... What to do?

If a similar situation is created, then the infection occurs again. It is advisable to examine and treat the sexual partner, for this he should contact a urologist.

Perhaps, the use of terzhinan does not need further explanation. The main thing you need to know is that it is one of the safest and preferred treatments for gynecological problems. However, if you have any other questions, contact your doctor - he will definitely clarify the points of interest for you.

Terzhinan is an antiprotozoal, antibacterial, anti-inflammatory and antifungal drug. Instructions for use recommends taking vaginal suppositories or tablets for the treatment of vaginitis caused by microorganisms sensitive to the drug. Reviews of patients and doctors confirm that this drug helps in the treatment of thrush (candidiasis), trichomoniasis and other infectious diseases of the female genital area.

Release form and composition

Dosage form of the drug Terzhinan - vaginal tablets: oblong, chamfered, flat (sometimes mistakenly called vaginal suppositories).

1 tablet contains: active ingredients: ternidazole - 200 mg, nystatin - 100,000 IU, neomycin sulfate - 100 mg or 65,000 international units (IU), prednisolone sodium metasulfobenzoate - 4.7 mg (3 mg prednisolone).

pharmachologic effect

Combined drug Terzhinan instructions for use refers to medicines that have antimicrobial, anti-inflammatory, antiprotozoal, antifungal effects. Contributes to the preservation and restoration of the integrity of the vaginal mucosa and the constancy of pH.

Nystatin is an antifungal antibiotic from the polyene group. It is highly effective against yeast-like fungi of the genus Candida, changes the permeability of cell membranes and slows down their growth.

Prednisolone has a pronounced anti-inflammatory, anti-allergic, anti-exudative effect.

Ternidazole has an antifungal effect, reduces the synthesis of ergosterol, changes the structure and properties of the cell membrane. It has a trichomonacid effect, it is also active against anaerobic bacteria, in particular Gardnerella spp.

Neomycin is a broad spectrum antibiotic. It acts bactericidal against gram-positive (Staphylococcus, Streptococcus pneumoniae) and gram-negative (Escherichia coli, Shigella dysenteriae, Shigella flexneri, Shigella boydii, Shigella sonnei, Proteus spp.) microorganisms.

What helps Terzhinan?

Indications for the use of the drug include:

mixed vaginitis;
vaginitis caused by fungi of the genus Candida;
bacterial vaginitis caused by banal pyogenic or conditionally pathogenic rod microflora;
bacterial vaginosis;
trichomoniasis of the vagina.

Instructions for use

Terzhinan tablets are intended for vaginal use by deep insertion into the vagina. The procedure is carried out before going to bed, in the supine position. Before administration, the tablet should be moistened with water for 0.5 minutes.

The duration of the course of treatment is 10 days; with confirmed mycosis - up to 20 days; prophylactic use - an average of 6 days.

Contraindications

Do not prescribe with hypersensitivity to the drug Terzhinan, from which these tablets can cause side effects.

Side effects

allergic reactions;
local irritation (especially at the beginning of therapy);
burning sensation.

Children, during pregnancy and lactation

The use of Terzhinan is possible from the second trimester of pregnancy.

Taking pills in the first trimester of pregnancy and during lactation is advisable if the expected benefit of treatment for the mother outweighs the possible risks to the fetus or newborn.

special instructions

It's important to know! With vaginitis and trichomoniasis, simultaneous treatment of sexual partners is necessary. Treatment should be continued during menstrual bleeding.

Content

The drug Terzhinan during pregnancy is taken in the form of suppositories inserted into the vagina for the treatment of diseases caused by the reproduction of pathogenic and opportunistic microorganisms. In 70% of women who are expecting a child, the optimal balance of the microflora of the genital organs occurs in the body due to changes in the functioning of the hormonal, immune and digestive systems. Terzhinan is prescribed to pregnant women not only for treatment, but also for the prevention of this pathology.

What is Terzhinan

When carrying a child, women often develop diseases of a bacterial and fungal nature - vaginitis, candidiasis, latent sexually transmitted infections. Candles Terzhinan during pregnancy is used to eliminate the unpleasant symptoms of the disease on the mucous membrane of the genital organs and inhibition of pathogenic microbes. This combined remedy effectively treats and prevents the development of inflammatory processes.

Active substance

The therapeutic effect of the drug is associated with the content of the components that make up its composition - such as:

Ternidazole is a substance with antibacterial activity. It is most effective against Trichomonas.
Nystatin is an antifungal component that fights candidiasis.
Neomycin - this substance belongs to the group of aminoglycoside antibiotics that treat purulent complications of infection.
Prednisolone is a corticosteroid that stops the development of inflammation processes.

Terzhinan - hormonal or not

The composition of the drug includes four active ingredients, one of which belongs to the group of corticosteroids. Prednisolone is a glucocorticoid that quickly reduces local inflammation of the vaginal mucosa, itching, burning. The dose of the content of this substance is small - 3 mg per 1 tablet. Terzhinan is classified as a hormonal drug, so its use is prohibited without the permission of a doctor.

Why is it prescribed to women

Vaginal suppositories and tablets are safe when taken correctly. This remedy is prescribed to ordinary patients and women expecting a baby. Treatment can be carried out during the period of menstruation. Terzhinan is prescribed for several conditions of the body and for the treatment of such infectious pathologies as:

colpitis;
vaginitis;
purulent discharge from the birth canal;
prevention of infection due to surgery;
the recovery period after the treatment of cervical erosion or the installation of a contraceptive spiral;
preparation for surgery and childbirth;
after suturing the cervix due to isthmic-cervical insufficiency;
to prevent the development of inflammation while wearing an unloading obstetric pessary;
genital ureaplasmosis;
trichomonas;
gardnerellosis;
candidiasis;
inflammation of the appendages.

Can it be used during pregnancy

Women in position should receive treatment under the supervision of a specialist. The doctor makes an assessment of the patient's condition during a periodic examination and according to the results of laboratory tests. Terzhinan for thrush during pregnancy and for the treatment of other infectious diseases of the genital organs is prescribed according to the same system as for women who are not expecting a baby. Having a local effect, the drug practically does not penetrate into the blood, so it is not considered dangerous for the fetus, but only in the later stages of gestation.

Terzhinan in early pregnancy

With vaginal use of Terzhinan during pregnancy, the active components penetrate into the bloodstream in small quantities. In the first three months of bearing a child, it is strictly forbidden to use the drug. This is a period of active formation of the internal organs and systems of the baby's body, and the components that the medicine contains can cause congenital pathologies. To suppress infections in the first trimester, it is recommended to use more gentle means.

In the 2nd trimester

For pregnant women in the second trimester, prohibitions are lifted that limit the use of a number of medications, but antibiotics are not included in this list. Terzhinan contains components that inhibit the activity of microorganisms, but it is approved for use. The drug is available in the form of vaginal tablets, so the amount of substances that can enter the bloodstream will be small and at this stage of the baby's development they will not cause harm.

In the 3rd trimester

Terzhinan and pregnancy in the third trimester are compatible. This is a very effective drug used for the treatment and prevention of infectious inflammation. To the indications for the appointment of Terzhinan during pregnancy for long periods, the treatment of the birth canal is added immediately before the appearance of the child in order to protect the baby from infection during the birth of the baby.

How Terzhinan works

The drug Terzhinan during pregnancy is highly active against a number of pathogens: trichomonas, gardnerella, fungi and other bacteria. Local application of the drug protects the epithelial cells of the mucous membranes of the genital organs and maintains the physiological acid-base balance of the internal environment of the vagina. Terzhinan, used during pregnancy, maintains the optimal ratio of beneficial bacteria with opportunistic microorganisms that live on the genitals.

Prednisolone, which is part of the drug, reduces the manifestation of local allergies, the amount of exudate, and inflammation. Ternidazole inhibits the reproduction of protozoa (Trichomonas) and some anaerobic bacteria. Neomycin kills staphylococci, E. coli, streptococci, shigella. Nystatin effectively fights the fungus. Microorganisms slowly develop resistance to Terzhinan.

Instructions for use during pregnancy

The ratio of the active substances of the drug is chosen so as to cause a synergistic, mutually reinforcing effect on pathogenic microbes, without affecting the natural microflora of the vagina. The medicine is released in the form of yellow vaginal tablets / suppositories. The active ingredients in its composition are contained in the following quantities:

prednisolone - 3 mg;
ternidazole - 200 mg;
neomycin sulfate - 100 mg;
nystatin - 100 thousand IU.

It is advisable to take Terzhinan immediately after menstruation, but menstruation is not considered a contraindication to the use of the drug. To prevent re-infection with pathogens, the sexual partner must also undergo treatment. The tool is allowed to be used not only by pregnant women, but also by lactating women, because it does not penetrate into breast milk. In addition, it was noted that the drug does not affect the reaction rate.

How to enter

The use of Terzhinan, like other medicines, has certain features. Candles are inserted into the vagina, following simple recommendations:

Before the introduction, tear the shell of the drug, place it in boiled water at room temperature for 30 seconds.
Insert a wet suppository / tablet deep into the vaginal cavity, lying on your back, bending your knees.
After placing the medicine in the birth canal, lie down for 15-30 minutes.
It is better to inject the tablet at bedtime and not get up after that, so that the melted drug does not leak out when you get up.
If menstruation starts, then continue the course of treatment.

Dosage

The drug does not affect the effectiveness of drugs taken orally, because the dose of active components that have penetrated into the blood is small. Terzhinan during pregnancy is taken intravaginally, one capsule per day. The drug should be injected deep into the vagina, preferably at bedtime. The course of treatment should not exceed 10 days. According to the decision of the attending physician in case of complicated vaginitis, the drug is prescribed to be taken for 3 weeks. For preventive purposes, the drug should not be used for more than 6 days.

Side effects of Terzhinan

Only the attending physician can prescribe the drug, because sometimes Terzhinan can cause side effects. In most cases, such a reaction is observed in the first days of treatment. Patients feel itching, burning, but gradually all the unpleasant symptoms disappear. Nuances:

If the side effect of the drug increases, then you should contact a specialist to replace Terzhinan with a similar drug.
Candles act locally, so an overdose is almost impossible.
To avoid possible complications, follow the doctor's recommendations.

Allocations after Terzhinan during pregnancy

Sometimes, when taking the drug, a woman may be frightened when she sees vaginal discharge. In such a situation, you need to decide why this is happening. Terzhinan is well tolerated during pregnancy, so the main reason for the appearance of liquid is the melting of the substance that makes up the suppository. The vaginal mucosa absorbs only part of the active ingredients, the rest flows out. The liquid preparation can leave the vagina for several hours. These secretions are not considered pathological. In order not to stain the linen, use sanitary pads during the treatment period.

Burning from Terzhinan

At the beginning of treatment with Terzhinan's suppositories, the vaginal mucosa may burn slightly and itching can be observed. After two or three days, such unpleasant phenomena should completely disappear against the background of a decrease in the inflammatory process. If the patient has an individual intolerance to any component of the drug, then the listed symptoms will intensify. In this case, she needs to urgently seek help from a doctor, and stop taking the prescribed remedy.

Contraindications

Terzhinan during pregnancy is absolutely contraindicated in the first trimester. During this period, the formation and development of the fetus occurs, and the drug contains active ingredients, even small doses of which can cause significant harm to the child. In severe conditions, when the expected benefit to the mother outweighs the possible risks to the child, the decision to prescribe the drug should be made by the doctor.

In addition, contraindications for the use of the drug include individual intolerance to the individual components that make up its composition, and allergic reactions. Most cases of burning sensation after taking the drug do not require discontinuation of the drug. This feeling goes away in a few hours. If unpleasant symptoms intensify and mucosal edema develops, then you need to take some kind of allergy remedy, and do not administer suppositories anymore.

Price Terzhinan

Prices for this drug practically do not differ in different cities. Vaginal tablets, manufacturer - Bouchard laboratory, France, package No. 6 cost from 336 to 363 rubles, No. 10 - 435-466 rubles. In addition, it is possible to purchase a medicine in an online pharmacy. Purchases can be received by mail or choose delivery to the addressee by courier company.