Almost every person is familiar with such a drug as No-shpa. This is an antispasmodic that has taken root in home medicine cabinets and has become a faithful savior from pain of a different nature. But whether it is possible to give this drug to a child, parents doubt, since the instructions clearly prescribe to be treated with No-shpa for people over 6 years old.

Indications for use No-shpy

The antispasmodic is produced in the form of tablets and capsules. The main indications for the use of yellow pills are:

• headache;
• spastic abdominal pain associated with constipation and ulcers, cystitis, cholecystitis, urolithiasis and pathologies of the duodenum 12;
• dry cough with bronchitis and laryngitis (to prevent spasm of the upper respiratory tract).

The instruction prescribes to give No-shpu to children at a temperature. But not every time babies have to take pills. If the temperature rises to the highest levels, but the skin remains moist and pink, the antispasmodic should not be used.

If the baby is shaken by a strong chill, and his skin looks pale and dry, this indicates a “white fever”. Knowing for sure that the child normally tolerates drotaverine, in order to expand blood vessels and adjust thermoregulation, the mother can give the child No-shpa to drink.

No-shpa for babies: is it worth the risk?

In the first months of life, babies are plagued by colic in the abdomen, increased gas formation and fermentation processes in the intestines. The culprits of discomfort are imperfect gastrointestinal tract and the enzyme system, which do not allow food masses to be fully digested and absorbed. Intestinal spasm in infants causes abdominal pain, profuse belching and regurgitation.

To improve the well-being of a restless baby, doctors recommend using teas, gas tubes, and other means. But if the air bubbles continue to burst the tummy, the newborn is prescribed No-shpu. Since tablets increase the load on the heart, they are not given whole.

The recommended dosage for babies under the age of one year is the fourth or eighth of a crushed tablet. A piece of antispasmodic crumbs is given only 1 time per day, ground into powder and diluted with water.

From 2 to 3 years, a single dosage of No-shpa for the treatment of children changes. Up to 6 years of age, the instruction leaflet suggests dividing during the day into 2-3 doses from 40 to 200 mg of the drug. For children older than 6 years, the dosage is slightly increased. This is 80 - 200 mg, divided into 2 - 5 doses.

No-shpa for teenagers

After 12 years, No-shpu for children is prescribed in amounts close to adult doses. The daily norm of an antispasmodic for an adult varies from 3 to 6 tablets, which corresponds to 120 to 240 mg. But for an organism that continues to form, this is a lot, and the appointment is distributed over the whole day so that so that the maximum amount of the drug does not exceed 80 mg (2 tablets).

If the pain is moderate and can be tolerated, to eliminate spasm, the child is given No-shpu 3 r. per day, 1 tablet. If the discomfort is strong enough or the remedy does not help, in agreement with the doctor, a single dose is adjusted to 2 tablets.

Contraindications to the use of No-shpa

Despite the high ability of No-shpa to relieve spasms, it can harm small patients if they suffer from:

1. bronchial asthma;
2. angle-closure glaucoma;
3. intolerance to lactose or galactose;
4. low blood pressure;
5. atherosclerosis of the coronary arteries;
6. individual intolerance to drotaverine;
7. severe heart, kidney or liver failure.

Dr. Komarovsky is concerned that the network contains advice from mothers on the treatment of infants with intramuscular injections of No-shpa. Without the knowledge of the doctor, it is forbidden to administer the drug to the baby. Do not aggravate the situation and do not risk the health of the child.

Possible side effects

Improper medication, violation of contraindications or non-compliance with dosages threatens the baby with not the most pleasant side effects. By their appearance, the body notifies of the failure of No-shpa self-treatment. So, from the side of digestion, negative reactions are manifested by nausea, vomiting, constipation.

The nervous system shows its dissatisfaction with the intake of drotaverine with dizziness or increased headache, insomnia or disturbing sleep. Problems of the cardiovascular system due to the use of an antispasmodic are rare. They are manifested by lethargy, palpitations, lack of initiative of the child.

Allergic effects are also rare, but you should not forget about them. Sneezing, tearing, a rash on the body - all this indicates intolerance to the drug. From the use of No-shpy should be abandoned.

What analogues replace No-shpu

If, for any reason, No-shpu cannot be used to treat a particular child, the drug is replaced with analogues. The cheapest medicines are Russian ones, the recipes of which are based on drotaverine or papaverine. These are:

• Nosh-Bra;
• Spasmol;
• Papaverine;
• Spazmonet;
• Drotaverine Forte;
• Drotaverine hydrochloride.

From foreign analogues, patients are offered Spazoverin or a strong drug No-shpalgin. The second medicine consists of drotaverine, paracetamol and codeine. You can buy it only with a doctor's prescription.

No-shpu can be called one of the most popular antispasmodics, often used by adults for abdominal cramps, headaches and other pains. Can children be treated with this drug, when is it used in childhood and what dosages are used?

Release form

No-shpa is produced by a Hungarian pharmaceutical company in two forms:

• In the form of small round yellow with an orange or greenish tinge tablets with the inscription "spa" on one side. One pack contains from 6 to 100 tablets, which are sold both in blisters and in plastic bottles.
• In the form of a greenish-yellow transparent solution, poured into dark glass ampoules of 2 ml. One box contains 5 or 25 ampoules.

Compound

Both formulations contain drotaverine hydrochloride, which is their main ingredient. Its amount in both 1 ampoule and 1 tablet is 40 mg. In order for the No-shpa tablet to be dense and keep its shape, talc, magnesium stearate and povidone, as well as lactose and starch obtained from corn, are added to its composition. In the injectable form of the drug, there is sodium disulfite, sterile water and 96% alcohol.

How does it work?

In No-shpa, a rather strong effect on smooth muscles is noted, the result of which will be the elimination of spasms and muscle relaxation. The drug affects the walls of the digestive tract, biliary and urinary tract, as well as the vascular walls.

The consequence of taking it will be a decrease in pain caused by spasms in the smooth muscles of the intestines, stomach, bladder and bile ducts.

Thanks to its effect on blood vessels, No-shpa helps with fever, which is called "white". A child with this fever will have pale skin and cool extremities. The condition is dangerously high risk of developing seizures, called febrile seizures. The use of No-shpa helps to expand blood vessels, improving blood supply to the limbs and heat transfer.

When is it appointed?

• Gastritis or peptic ulcer of the stomach.
• Dry cough (medication may be taken at bedtime to prevent spasms in the airways).
• Toothache.
• High temperature with simultaneous spasm of skin vessels.

Application

The instructions for tableted No-shpa contain information that this form of the drug is not prescribed for children under 6 years of age. Annotation to the solution for intramuscular or intravenous injections generally prohibits the use of such a medication in children, referring to the fact that clinical studies of the effect of No-shpa on young patients have not been conducted. However, in practice, doctors often prescribe No-shpu to children both in tablets and in injections.

According to doctors, these drugs are prohibited for babies under one year old, and at the age of 1 to 6 years they can be used, but with one important caveat - only a doctor should prescribe medicine to children under six years of age.

The specialist will determine whether No-shpa is really needed in the treatment of a particular child, and will also recommend the correct dosage based on age.

Contraindications

No-shpa treatment is prohibited:

• With serious kidney disease, due to which the excretory function is impaired.
• With severe heart failure.
• With severe violations of the liver.

• With hypersensitivity to any ingredient of the drug.
• With hereditary diseases, due to which the absorption of carbohydrates is impaired (this is the reason not to prescribe pills).
• With severe pain in the abdomen (the drug can "lubricate" the clinical picture of surgical pathology and interfere with timely treatment).

If the child has low blood pressure, the medicine is used very carefully, because it can provoke a collapse.

Side effects

Judging by the reviews, patients in most cases tolerate No-shpu well, but occasionally the medication causes constipation, allergic rashes, insomnia, skin itching, hypotension, dizziness, nausea or headache. Such side effects are diagnosed in less than 0.1% of those taking No-shpu. When they appear, the medicine is canceled or its dose is reduced.

Dosage

If the patient is not yet six years old (for example, a child is only 4 years old), a pediatrician, urologist, gastroenterologist or other specialist who prescribes No-shpu should determine a single dose of medication. It can be a quarter, a third or a half of a tablet. If a small patient still does not know how to swallow solid medicine, No-shpu is ground into powder in the dosage prescribed by the doctor, and then mixed with water or sweet syrup.

The frequency of taking the pill will depend on the severity of the child's condition. Sometimes a single application of the drug is enough, and some patients are given the drug up to 4-6 times a day. The duration of treatment should also be determined by the doctor, taking into account both the clinical picture and the response to therapy. The drug in injections is prescribed in exceptional cases, for example, if the child is unable to take pills or there is a high risk to the health of the baby. Most often, the injectable form of No-shpa is used in childhood with fever, combined with an antipyretic drug (often Analgin) and an antihistamine (

No-shpa has a pronounced antispasmodic effect on the smooth muscles of the internal organs.

It is used for spasms of the gastrointestinal tract, biliary tract, angina pectoris, urolithiasis, peripheral vessels. The active ingredient is drotaverine.

The effect of taking this drug occurs within a few minutes. After half an hour, the phase of the maximum effect from taking this antispasmodic begins.

Can be used orally (tablets) and aprenterally (solution for injection).

Clinical and pharmacological group

Myotropic antispasmodic.

Terms of dispensing from pharmacies

Released without a doctor's prescription.

Prices

How much does No-shpa cost in pharmacies? The average price is at the level of 75 rubles.

Release form and composition

No-shpa tablets are small, round in color and yellow in color.

1. Tablet composition: 40 mg of drotaverine (in the form of hydrochloride), magnesium stearate, povidone, talc, corn starch, lactose (in the form of monohydrate).
2. Forte tablets have an identical composition. The only difference is the higher concentration of the active substance (80 mg/tab.).
3. The composition of No-Shpa in ampoules: drotaverine hydrochloride at a concentration of 20 mg / ml, 96% ethanol, sodium metabisulfite, water for injection.

No-shpa tablets are packaged in a blister of 6 and 24 pieces, as well as in glass bottles of 60 and 100 pieces. The cardboard pack contains one blister or bottle with the appropriate number of tablets, as well as instructions for using the drug.

Pharmacological effect

The main active ingredient of No-shpa is drotaverine hydrochloride, an antispasmodic that has a positive effect on the smooth muscles of the genitourinary and biliary tract, as well as the gastrointestinal tract. The substance contributes to the effective removal of puffiness, normalizes blood circulation and eliminates inflammation in muscle tissues.

The main advantage is the absence of a negative effect of the components of the drug on the functioning of the nervous system. After taking the tablets, the result is felt after 20 minutes, a greater effect is achieved after 1 hour. When the solution is administered intravenously - after 2-5 minutes, the maximum effect - after 30 minutes. Complete excretion of drotaverine from the body occurs 72 hours after ingestion.

Indications for use

What helps? No-shpa can be used both as a main and as an auxiliary therapeutic agent for a number of pathological conditions:

1. colic;
2. Spasm of the arteries;
3. spastic constipation;
4. Pyelite;
5. Tenesmus;
6. Proctitis;
7. Endarteritis;
8. Spasm of cerebral vessels.

In addition, No-shpa is used for certain conditions, to alleviate and relieve unpleasant symptoms.

No-Shpa for children

It is advisable to give medicine to children with cystitis and nephrolithiasis, sharp spasms of the duodenum or stomach, gastritis, enteritis, colitis, flatulence, constipation, spasm of peripheral arteries, high fever and severe headaches.

Tablets of 40 mg are prescribed for children from the age of six. Clinical studies of the safety and efficacy of Forte tablets in children have not been conducted.

Contraindications

1. Lactase deficiency, hereditary galactose intolerance, galactose-glucose malabsorption syndrome (tablets, due to the presence of lactose monohydrate in their composition);
2. Age up to 6 years (tablets);
3. The period of breastfeeding (due to the lack of necessary clinical data confirming the safety and efficacy of No-shpa for this group of patients);
4. Severe heart failure (low cardiac output syndrome);
5. severe liver or kidney failure;
6. Hypersensitivity to the components of the drug.

No-shpu should be used with caution against the background of arterial hypotension, in children and during pregnancy.

With intravenous administration of an injection solution, due to the risk of collapse, the patient must lie down.

Use during pregnancy and lactation

During pregnancy, it is possible to use the drug No-shpa only in cases where the expected benefit is several times greater than the possible danger to the development and health of the fetus. In this case, the dosage is selected strictly individually.

Dosage and method of application

The instructions for use indicate that when taking No-shpa without consulting a doctor, the recommended duration of taking the drug is usually 1-2 days. In cases where drotaverine is used as adjuvant therapy, the duration of treatment without consulting a doctor may be longer (2-3 days). If the pain syndrome persists, the patient should consult a doctor.

The effectiveness of the drug No-Shpa is three to four times higher than the effectiveness of Papaverine. In addition, the drug is characterized by 100% bioavailability. When taking a tablet, drotaverine is very quickly absorbed from the gastrointestinal tract: the half-absorption period of the substance is 12 minutes.

Dosages of No-shpa:

• Adults are prescribed 1-2 tablets. at one time 2-3 times / day. The maximum daily dose is 6 tab. (corresponding to 240 mg).
• Clinical studies with the use of drotaverine in children have not been conducted. In the case of the appointment of the drug No-shpa for children aged 6 to 12 years - 40 mg (1 tab.) 1-2 times / day, for children over the age of 12 years - 4 mg (1 tab.) 1- 4 times / day or 80 mg (2 tablets) 1-2 times / day. The maximum daily dose is 160 mg (4 tablets).

If the patient can easily self-diagnose the symptoms of his illness, because they are well known to him, the effectiveness of the treatment, namely the disappearance of pain, is also easily assessed by the patient. If within a few hours after taking the drug at the maximum single dose, there is a moderate decrease in pain or no decrease in pain, or if the pain does not significantly decrease after taking the maximum daily dose, it is recommended to consult a doctor.

When using a bottle with a polyethylene stopper equipped with a piece dispenser: before use, remove the protective strip from the top of the bottle and the sticker from the bottom of the bottle. Place the bottle in the palm of your hand so that the dosing hole on the bottom does not rest against the palm. Then press on the top of the vial, causing one tablet to fall out of the dosing hole on the bottom.

Side effects

Side effects against the background of the use of No-shpa are quite rare. The most common of these are:

• feeling of increased heartbeat;
• nausea;
• itchy rash on the skin;
• feeling of anxiety;
• insomnia;
• lowering blood pressure;
• constipation;
• headache;
• angioedema;
• dizziness.

Overdose

A significant excess of the recommended therapeutic dose of No-shpa tablets can lead to a violation of the rhythm of heart contractions (arrhythmia), as well as a violation of intracardiac conduction, up to a complete blockade with cardiac arrest.

Overdose treatment consists in washing the stomach, intestines, taking intestinal sorbents (activated charcoal), as well as conducting symptomatic therapy in a medical hospital.

special instructions

The composition of the 40 mg tablets includes 52 mg of lactose monohydrate, as a result of which complaints from the digestive system are possible in patients with lactose intolerance. This form is not intended for patients with lactase deficiency, galactosemia, or glucose/galactose malabsorption syndrome.

If any adverse reactions occur, the issue of driving vehicles and working with mechanisms requires individual consideration. In the event of dizziness after taking the drug, you should avoid engaging in potentially hazardous activities, such as driving vehicles and working with mechanisms.

drug interaction

PDE inhibitors, like papaverine, weaken the antiparkinsonian effect of levodopa. When prescribing the drug No-shpa simultaneously with levodopa, it is possible to increase rigidity and tremor.

With the simultaneous use of drotaverine with other antispasmodics, including m-anticholinergics, there is a mutual enhancement of the antispasmodic effect.

Tablets are round, biconvex, yellow with a greenish or orange tint, marked "spa" on one side.

Compound

Drotaverine hydrochloride 40 mg

Excipients: magnesium stearate, talc, polyvidone, corn starch, lactose monohydrate.

Pharmacodynamics

Antispasmodic. Drotaverine is an isoquinoline derivative that exhibits an antispasmodic effect on smooth muscles by inhibiting the enzyme phosphodiesterase 4 (PDE4). Inhibition of the PDE4 enzyme leads to an increased concentration of cAMP, which inactivates the myosin kinase (MLCK) light chain, which in turn leads to smooth muscle relaxation.

Drotaverine inhibits the PDE4 enzyme in vitro without inhibiting the PDE3 and PDE5 isoenzymes. Apparently, PDE4 is functionally very important in reducing the contractility of smooth muscles, so selective PDE4 inhibitors can be effective in the treatment of hyperkinetic diseases and diseases associated with spastic conditions of the gastrointestinal tract.

The enzyme hydrolyzing cAMP in myocardial and vascular smooth muscle cells is mainly a PDE3 isoenzyme, which explains the high effectiveness of drotaverine as an antispasmodic in the absence of a pronounced effect on the cardiovascular system and serious cardiovascular adverse reactions. The drug is effective in spasms of smooth muscles of both nervous and muscular etiology. Regardless of the type of autonomic innervation, drotaverine acts on the smooth muscles of the gastrointestinal tract, biliary tract, as well as the genitourinary and vascular systems. Due to the vasodilating effect, No-shpa® improves tissue blood supply.

Pharmacokinetics

Suction and distribution

When administered orally and parenterally, drotaverine is rapidly and completely absorbed. Cmax is achieved within 45-60 minutes. It binds to plasma proteins (alpha albumin, alpha and beta globulins).

Metabolism and excretion

Metabolized in the liver. T1 / 2 - 16-22 hours. After 72 hours, drotaverine is excreted from the body mainly in the form of metabolites, 50% in the urine, 30% in the feces.

Side effects

From the digestive system: rarely - nausea, constipation.

From the side of the central nervous system: rarely - headache, dizziness, insomnia.

From the side of the cardiovascular system: rarely - palpitations; very rarely - arterial hypotension.

Other: very rarely - allergic reactions (with parenteral administration, especially in patients with hypersensitivity to bisulfite).

Selling Features

Released without a prescription

Special conditions

The composition of the tablets includes 52 mg of lactose, so the drug in the form of tablets is not prescribed for patients with lactase deficiency, galactosemia or impaired glucose / galactose absorption syndrome.

The composition of the solution for intravenous and intramuscular administration includes sodium bisulfite, which can cause allergic reactions, including anaphylactic and bronchospasm, in sensitive individuals (especially in individuals with bronchial asthma or a history of allergic reactions). In case of hypersensitivity to sodium metabisulphite, parenteral use of the drug should be avoided.

Influence on the ability to drive vehicles and control mechanisms

When taken orally in therapeutic doses, drotaverine does not affect the ability to engage in potentially hazardous activities.

After parenteral (especially intravenous) administration of the drug, it is recommended to refrain from driving vehicles and operating mechanisms for 1 hour (after application).

Indications

Spasms of smooth muscles associated with diseases of the biliary tract: cholelithiasis, cholecystitis, pericholecystitis, cholangitis, papillitis;

Spasms of smooth muscles of the urinary system: urolithiasis, pyelitis, cystitis, bladder tenesmus;

In physiological childbirth - shortening the phase of cervical dilatation and thereby reducing the total duration of labor (for a solution for intravenous and intramuscular injection).

As adjuvant therapy:

With spasms of smooth muscles of the gastrointestinal tract: peptic ulcer of the stomach and duodenum, gastritis, spasms of the cardia and pylorus, enteritis, colitis, accompanied by constipation and flatulence;

Tension headaches (for oral administration);

With gynecological diseases (dysmenorrhea);

Strong labor pains (for solution for intravenous and intramuscular administration).

When used as an adjuvant, the drug is administered parenterally when it is impossible to use tablets.

Contraindications

Severe renal failure;

severe liver failure;

Severe heart failure (low cardiac output syndrome);

Children's age up to 1 year (for tablets);

Hypersensitivity to drotaverine or to any excipient of the drug (especially to sodium metabisulfite - for a solution for intravenous and intramuscular administration).

Use the drug with caution in arterial hypotension. When the / in the introduction of the drug, the patient should be in the supine position because of the risk of collapse.

drug interaction

With the simultaneous use of No-shpa®, it can reduce the anti-Parkinsonian effect of levodopa.

The composition of the medicinal product NO-SHPA

NO-SHPA®

tab. 40 mg, № 20 UAH 6.81

tab. 40 mg, № 100 UAH 20.38

Drotaverine hydrochloride 40 mg

Other Ingredients: Magnesium stearate, talc, lactose, corn starch, povidone.

No. P.01.03/05723 from 10.01.2003 to 10.01.2008

rr d / in. 40 mg amp. 2 ml, № 25 UAH 42.82

Drotaverine hydrochloride 20 mg/ml

Other Ingredients: Sodium Metabisulphite, Ethyl Alcohol 96%, Water for Injection.

No. P.01.03/05724 from 17.08.2007 to 17.08.2011

NO-SHPA® FORTE

tab. 80 mg, #10

tab. 80 mg, № 20 UAH 12.31

Drotaverine hydrochloride 80 mg

Other Ingredients: Magnesium stearate, talc, povidone, corn starch, lactose.

Dosage form

tablets

Pharmacological properties

Drotaverine, an isoquinoline-derived antispasmodic, acts directly on smooth muscles by inhibiting phosphodiesterase and intracellular cAMP accumulation, which leads to smooth muscle relaxation due to inactivation of the myosin kinase light chain. The antispasmodic effect of drotaverine does not depend on the nature of autonomic innervation, the drug is active against smooth muscles of the gastrointestinal, biliary, urogenital and cardiovascular systems.

Drotaverine is rapidly absorbed both parenterally and orally. The maximum concentration in blood serum is reached in 45-60 minutes after oral administration. Metabolized in the liver. The half-life is 16–22 hours. In 72 hours, it is almost completely excreted from the body, about 50% in the urine, 30% in the feces. Basically - in the form of metabolites, unchanged in the urine is not determined. Drotaverine and / or its metabolites practically do not penetrate the placental barrier.

Indications for use NO-ShPA

No-Shpa

Spasms of smooth muscles caused by diseases of the biliary tract - cholelithiasis, cholangiolithiasis, cholecystitis, pericholecystitis, cholangitis, papillitis; to reduce the phase of cervical dilatation of physiological labor and the duration of labor; in the placental stage of labor to facilitate the implementation of the reception of Crede and the prevention of incarceration; spasms of smooth muscles of the urinary tract with nephrolithiasis, urethrolithiasis, pyelitis, cystitis, bladder tenesmus. The drug can be used as adjuvant therapy for spasms of smooth muscles of the digestive tract - with peptic ulcer of the stomach and / or duodenum, gastroduodenitis, enteritis, spastic colitis, cardiospasm and pyloric spasm, irritable bowel syndrome, spastic constipation, flatulence, pancreatitis; with gynecological diseases - dysmenorrhea, adnexitis, severe painful labor pains, tetany of the uterus, threatening abortion; with headache of vascular origin.

No-Shpa Forte

Spasms of smooth muscles caused by diseases of the biliary tract, cholelithiasis, cholangiolithiasis, cholecystitis, pericholecystitis, cholangitis, papillitis. Spasms of smooth muscles of the urinary tract with nephrolithiasis, urethrolithiasis, pyelitis, cystitis, bladder tenesmus. The drug is effective and safe when used as an adjuvant therapy for smooth muscle spasms of the gastrointestinal tract - peptic ulcer of the stomach and duodenum, gastritis, enteritis, colitis, cardiospasm and pyloric spasm, irritable bowel syndrome, spastic constipation or flatulence, pancreatitis; with gynecological diseases - dysmenorrhea, adnexitis; with headache of vascular origin.

Contraindications

hypersensitivity to drotaverine or any component of the drug, severe hepatic, renal or heart failure (low cardiac output syndrome). Lactase deficiency, galactosemia, or glucose/galactose malabsorption syndrome. breastfeeding period. Children under the age of 1 year.

Usage Precautions

the drug can cause dyspepsia in patients with lactose intolerance due to its content in tablets. With arterial hypotension, use with caution. In / injected only in the supine position (risk of collapse). In case of hypersensitivity to sodium metabisulphite, parenteral use of the drug should be avoided. After parenteral, especially intravenous administration of the drug, it is recommended to refrain from driving and performing work requiring increased attention for 1 hour.

The experiment did not establish the presence of a teratogenic and embryotoxic effect in the drug. Does not affect the course of pregnancy. During lactation, the drug should be prescribed taking into account the ratio of risk and benefit.

Interaction with drugs

care must be taken while using No-Shpa with levodopa, since the anti-Parkinsonian effect of the latter is reduced and there is an increase in tremor and rigidity.

Method of application and dosage NO-ShPA

No-Shpa

Adults inside - 120-240 mg / day in 2-3 doses. For attacks of renal or hepatic colic, 40–80 mg (2–4 ml) is slowly (over 30 s) administered intravenously, usually in combination with analgesics. In other spastic conditions, it is administered intramuscularly or s / c at a dose of 40–80 mg, if necessary, it is administered at the same dose again up to 3 times a day, or subsequently administered orally at a daily dose of 120–240 mg.

To alleviate cervical dilatation during childbirth, it is administered at a dose of 40 mg intramuscularly at the onset of labor. If this dose is ineffective, repeat the same dose after 2 hours.

Children aged 1 year - 6 years inside - 40-120 mg / day (2-3 times 1/2-1 tablet), over 6 years old - 80-200 mg / day (2-5 times 1 tablet).

Side effects

side effects noted in clinical studies and caused by taking drotaverine are classified by organs and systems, as well as by frequency of occurrence: very often (≥1/10), often (≥1/100, but
Gastrointestinal disorders: rarely - nausea, constipation.

From the side of the nervous system: rarely - headache, dizziness, insomnia.

Since the cardiovascular system: rarely - tachycardia, arterial hypotension.