Prohibited while breastfeeding

Forbidden to children

Has restrictions for the elderly

Has limitations for liver problems

Has limitations for kidney problems

Coldact Flu Plus is a cold medicine that has gained popularity over the past few years among people of all ages due to its ease of use and wide spectrum of action. However, despite the prevalence, the drug can be extremely dangerous if used incorrectly, so it is important to study the detailed information about the drug.

general information

Coldact Flu is a long-acting antiviral agent that not only eliminates the symptoms of colds and flu, but also fights the root cause of the disease.

Drug group, INN, scope

Koldakt (INN - Paracetamol + Phenylephrine + Chlorphenamine) is an analgesic and antipyretic, which is used as a symptomatic treatment for ARVI and influenza. Helps fight nasal congestion, high fever and other symptoms of a viral infection.

Forms of release and prices for the drug, average in Russia

Available in the form of hard, transparent capsules with a bright red cap. Or in the form of an orange suspension with a specific odor for oral administration. The content of the capsules consists of white, or almost white, orange and yellow granules. In a carton box 1 blister containing 10 capsules and instructions for use. 1 suspension package contains a 60 ml vial, dosing spoon and instructions.

The table shows the average price in the territory of the Russian Federation.

Composition

The drug contains a combination of 3 active substances at once, the combined action of which is aimed at combating several symptoms of colds and flu at once:

1. Paracetamol as an analgesic relieves pain and reduces fever.
2. Phenylephrine as an α-agonist removes puffiness.
3. Chlorphenamine as an antihistamine reduces allergic manifestations such as watery eyes, itching and redness of the eyes.

Combination drugs for colds

Dosage of active ingredients: chlorpheniramine maleate, paracetamol, phenylephrine hydrochloride in a ratio of 8/200/25 mg, respectively. Other components: ethyl cellulose, talc, povidone, microcrystalline cellulose, dyes (E223, E124, E110 and E104), nonpareil granules. Capsule composition: sodium lauryl sulfate, gelatin, dyes.

Suspension composition:

1. The active ingredients are identical to those in the capsule form, but at a lower dosage (2/125/5mg).
2. Additional components: glycerin, flavors, purified water, sucrose, sodium saccharinate, sodium citrate, orange-yellow dye.

Pharmacodynamics and pharmacokinetics

The drug is a combined long-acting drug that has antipyretic, analgesic effects, and also blocks alpha-adrenergic receptors, in particular:

1. Paracetamol relieves headache and muscle pain, reduces pain in the throat and joints, by slowing down the synthesis of prostaglandins and influencing the thermoregulation department.
2. Chlorphenamine helps fight watery eyes and itchy nose as an antihistamine.
3. Phenylephrine eliminates swelling of the nasal mucosa as an alpha-adrenergic agonist.

The therapeutic effect becomes noticeable 40-60 minutes after ingestion. Metabolism of active substances occurs in isolation. The half-life of paracetamol is on average 2-2.5 hours. The substance is rapidly absorbed in the intestine, practically without binding to blood proteins (only 10%). The process of metabolism for the most part occurs in the liver, and the drug is excreted in the urine throughout the day.

The half-life of chlorpheniramine maleate is 8 hours, the decay products of the substance are excreted in the urine. Most of the phenylephrine hydrochloride is excreted in the urine unchanged, the remains are inactivated by monoamine oxidase.

Indications and contraindications

Due to the combination of substances in the composition of the drug, the list of both its indications and contraindications is quite extensive. The list of conditions and diseases, from which the drug helps:

• flu;
• headache;
• pain in muscles and joints;
• runny nose.

Symptoms of SARS

Contraindications:

• allergy to any constituent substance;
• hemolytic anemia;
• dysfunction of the liver and kidneys;
• Gilbert's syndrome;
• blood diseases;
• problems with the CCC;
• bronchial asthma;
• Dubin-Johnson syndrome;
• diseases of the endocrine system;
• glaucoma;
• stomach ulcer;
• bladder neck obstruction;
• alcoholism.

Children under 12 years of age are not allowed to take the capsules. You can use the suspension for children from 6 years of age with dosage restrictions.

Rules for taking and dosing

Instructions for use Coldact Flu Plus specifies that both forms of release are taken orally. Frequency and duration of administration:

In the case of using a means to reduce the temperature, the duration of admission is no more than 3 days, as an analgesic - 5.

Possible side effects and overdose

In most episodes, the drug is well tolerated, without any adverse reactions. In rare cases, if the dosage is violated, the following side effects can be observed:

If the dosage is violated, the following reactions indicated in the table may occur.

Treatment includes emergency gastric lavage, activated charcoal, respiratory and circulatory monitoring. In severe cases, ventilation may be necessary.

Compatibility and special instructions

Koldakt contains 3 active ingredients at once, each of which is not compatible with different types of drugs, which makes taking the drug with the presence of other concomitant diseases almost impossible.

MAO inhibitors are not compatible with any of the components of the drug. The use of Koldakt is not recommended earlier than 2 weeks after taking them. The drug is not recommended to be combined with other antiviral agents.

During therapy, it is recommended to give up driving and other activities that require a quick reaction and increased concentration. Not compatible with alcohol and alcohol-containing products. With long-term therapy, the drug is able to distort blood tests for glucose and plasma uric acid.

If the therapeutic effect does not occur within a few days after taking the drug, and the fever only intensifies, it is urgent to consult a doctor. Elderly people should be used with extreme caution and only after consulting a specialist who will evaluate the risk/benefit ratio.

Analogues

The tool has many analogues, the most effective of them are presented below.

1. Pharmacological action

Drug group:

Therapeutic effects of Codelac:

• Analgesic;
• Pronounced antitussive;
• Pronounced expectorant;
• Decreased viscosity of sputum;
• Strengthening the secretory activity of the bronchi.

Peculiarities:

• In therapeutic doses, the drug does not depress the respiratory center;
• The action of the drug lasts for 6 hours.

2. indications for use

The drug is used for:

• Symptomatic elimination of unproductive cough in various diseases of the respiratory system.

Average dosage:

1 tablet 2-3 times a day;

Minimum single dose:

50 mg of the drug;

Maximum daily dose:

200 mg of the drug.

Application Features:

• The drug must be taken with a sufficient amount of liquid;
• According to the instructions, patients suffering from a decrease in kidney activity, it is necessary to reduce the dosage of the drug.

4. Side effects

Nervous system:

Dizziness, headaches, drowsiness;

Hypersensitivity reactions:

Rash on the skin;

• Digestive system: stool disorders, stomach pain, vomiting, nausea, dryness of the oral mucosa;

drug addiction;

Results of laboratory researches:

Positive doping control.

5. Contraindications

• Respiratory failure and;
• Hypersensitivity or individual intolerance to Codelac or its components;
• Age less than 2 years;
• Simultaneous use of Codelac with drugs that depress the central nervous system, hypnotics and sedatives, ethyl-containing drugs, antihistamines, central painkillers, antipsychotic drugs, expectorants, mucolytics or anxiolytics.

Apply with caution:

• Functional disorders of the kidneys;
• Increased intracranial pressure;
• Driving a vehicle or operating complex mechanisms.

6. During pregnancy and lactation

7. Interaction with other drugs

Simultaneous use of Codelac with:

Chloramphenicol:

Potentiation of the action of Codelac;

Enveloping, astringent enterosorbents:

Decreased concentration of Codelac;

Cardiac glycosides:

Increasing their concentration.

8. Overdose

Symptoms:

Nervous system:

Drowsiness;

Sense organs:

nystagmus;

Digestive system:

Vomit;

The cardiovascular system:

bradycardia;

Respiratory system:

Bradypnea;

Urinary system:

Bladder atony.

Treatment of overdose with Codelac:

• Cancellation of the drug;
• Gastric lavage;
• Taking an antidote;
• symptomatic treatment.

9. Release form

10. Storage conditions

• Dry dark place;
• Lack of access for children and strangers.

Not longer than 4 years.

11. Composition

• codeine - 8 mg;
• sodium bicarbonate - 200 mg;
• licorice root powder - 200 mg;
• lanceolate thermopsis herb powder - 20 mg;
• Excipients: potato starch, microcrystalline cellulose, talc.

12. Terms of dispensing from pharmacies

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* Instructions for medical use for Codelac are published in free translation. THERE ARE CONTRAINDICATIONS. BEFORE USE, IT IS NECESSARY TO CONSULT WITH A SPECIALIST

Instructions (information for consumers) on the use of the drug COLDACT FLU PLUS (COLDACT FLU PLUS)

Coldact Flu Plus

Prolonged action capsules.

Combined drug of prolonged action. Chlorpheniramine has an anti-allergic effect, eliminates lacrimation, itching in the eyes and nose. Paracetamol has an antipyretic and analgesic effect: it reduces the pain syndrome observed in colds - sore throat, headache, muscle and joint pain, reduces high temperature. Phenylephrine has a vasoconstrictive effect - reduces swelling and hyperemia of the mucous membranes of the upper respiratory tract and paranasal sinuses.

The drug is intended to relieve the symptoms of colds, flu, SARS.

Hypersensitivity to any of the constituent components, severe atherosclerosis of the coronary arteries, arterial hypertension, diabetes mellitus, thyrotoxicosis, angle-closure glaucoma, severe diseases of the liver, kidneys, heart, lungs (including bronchial asthma), bladder, gastric ulcer and 12 duodenal ulcers, diseases of the pancreas,
difficulty urinating with prostate adenoma, diseases of the blood system, deficiency of the enzyme glucose-6-phosphate dehydrogenase, children under 12 years of age.

Pregnant women and nursing mothers, as well as patients undergoing treatment with other drugs, in particular monoamine oxidase inhibitors, should not take the drug without a doctor's instructions. If, despite taking the drug, the disease is accompanied by ongoing fever or repeated increases in temperature are observed, you should consult a doctor. Do not take with alcohol, with other drugs containing paracetamol. When using Coldact Flu Plus, it is undesirable to use sleeping pills, tranquilizers and other psychotropic drugs. When taking the drug, it is not recommended to drive a car.

For influenza and acute respiratory viral infections, adults and children over 12 years of age are prescribed 1 capsule every 12 hours for 1-3 days, for allergic rhinitis - 3-6 days, for sinusitis - 6-12 days. Duration of admission as an antipyretic - no more than 3 days; as an anesthetic - no more than 5 days.

In individuals with hypersensitivity to the components of the drug, an increase in blood pressure, tachycardia, the appearance of drowsiness, dizziness, dry mucous membranes, loss of appetite, rarely gastrointestinal disorders, very rarely obstruction of urine outflow, allergic reactions in the form of rash and itching. Given the presence of paracetamol: rarely - a violation of the blood system (thrombocytopenia, leukopenia, agranulocytosis); with prolonged use in high doses, hepatotoxic and nephrotoxic effects are possible.

In autumn and winter, people with a weakened immune system often encounter respiratory viral diseases. To get rid of such diseases, you should use the medicine Coldact Flu Plus, which quickly eliminates the symptoms of a cold. Before starting therapy, you must carefully study the instructions for use of Coldact Flu Plus in order to use the drug correctly.

In the pharmacy you can find tablets and capsules, which are sold in small packages. Each of them contains one plate of ten tablets. In the manufacture of the drug, such an active ingredient as chlorphenamine maleate is used. This trace element has an anti-inflammatory effect. Also, when creating a medication, phenylephrine hydrochloride and paracetamol are added.

For the manufacture of capsule shells, the following microelements are used:

• dye;
• hydroxybenzoate;
• water;
• gelatin.

pharmachologic effect

"Coldact Flu Plus" refers to drugs with a combined action that effectively fight colds. The medicine is distinguished by antihistamine and antipyretic properties, with the help of which most of the symptoms of the disease are eliminated. Paracetamol, which is part of the drug, helps to eliminate headaches.

When the components of the drug enter the body, they do not affect the functioning of the digestive organs and their mucous membrane in any way. Therefore, side effects from the use of Coldact Flu are extremely rare.

Indications for admission

The medicine is used to get rid of colds. The most common include:

• Flu. Such an infectious disease is accompanied by chills, headaches, dizziness, coughing and nasal congestion. Most often, people become infected with the flu in winter, when the body is cold.
• Sinusitis. The development of pathology is accompanied by inflammation of the nasal sinuses, due to which nasal breathing worsens and a severe runny nose appears. Sinusitis is caused by bacterial infections that enter the nostrils.

Contraindications

Not everyone can use Coldact Flu Plus to recover from a cold, since the drug has a number of contraindications. It is recommended that you familiarize yourself with them in order to understand who should not drink such pills.

The drug will have to be abandoned by patients with a high degree of sensitivity to the components from which the tablets are made. Also, the drug is contraindicated in people who have problems with the functioning of the kidneys and liver.

Doctors do not recommend the use of "Coldact Flu Plus" for people with disorders of the cardiovascular system. These include anemia, atherosclerosis, hypertension and arrhythmia.

Instructions for "Koldakt"

Instructions for use of the drug will help to understand the main nuances of the use of the drug in the treatment of catarrhal pathologies. Teenagers and adults should take Ranbaxi Coldact Flu Plus every day, two capsules after meals. The course of treatment lasts about a week. If the drug is used to get rid of fever, you will have to reduce the duration of the treatment course to 3-4 days.

During the treatment of children under ten years of age, the dosage is reduced to one capsule per day. At the same time, the duration of the therapeutic course is also reduced to three days. This is enough to cure a cold.

Side effects

Sometimes, if Coldact Flu Plus is used incorrectly, unpleasant side effects appear, due to which the patient's well-being deteriorates sharply. Common side effects that appear after long-term use of tablets include an increase in blood pressure, sleep problems, headaches, drying of the mucous membranes in the mouth, anemia.

In rare cases, due to the medication, allergic reactions and problems with urination appear.

Overdose

Overdose symptoms may appear if you take too many tablets every day. The main signs of an overdose include loss of appetite, disruption of the digestive system, vomiting, nausea, and blanching of the skin.

If the above symptoms appear, you should immediately consult a doctor so that he can prescribe treatment. Most often, to eliminate the symptoms of an overdose, a bowel cleansing is performed. This will help cleanse the body of drug residues.

Interaction with other drugs

Often, in the treatment of colds, complex therapy is used, in which the patient uses several different drugs at once. Therefore, it is necessary to study in advance whether Coldact Flu Plus is compatible with other medicines.

You can not combine the drug with drugs that contain rifampicin. Also, tablets cannot be combined with antipsychotic medications and antidepressants, since these drugs cause constipation and the mucous membrane in the oral cavity dries up.

Use during pregnancy and lactation

Experts do not recommend drinking Coldact Flu Plus for young pregnant girls and mothers who feed their newborn with breast milk. The components from which the tablets are made can interfere with the development of the young fetus and infant.

Terms of sale in pharmacies

Some people think that it is impossible to buy such pills in a pharmacy without a special prescription, but this is not so. To buy Coldacta Flu Plus, you just need to visit a pharmacy.

Terms and conditions of storage

Many do not pay much attention to the storage of medicines at home. If you store tablets for a long time in an inappropriate place for this, they will quickly deteriorate and lose their beneficial properties.