Actovegin substitute, domestic analogue. Cheap and high-quality analogues of Actovegin. Medicine "Mexidol"

Is Actovegin a common drug that has a positive effect on the body’s regenerative processes and is used in various medical fields? including in the treatment of hypertension. The main disadvantage is the high price, which requires a search for cheaper substitutes that have the same beneficial properties.

Advantages and disadvantages of the product

Due to the natural origin of the active component of the purified blood extract of young cattle, the drug has the following advantages:

  • Increases the rate of cellular material metabolism.
  • Normalization of blood circulation.
  • Increases the regenerating and renewal properties of cells.
  • Increases cellular energy reserves.
  • Prevents and reduces the consequences of oxygen starvation of various types of tissues.
  • Increases the body's protective and adaptive powers.
  • Safe to use for pregnant and lactating women.
  • Use in newborns from the first days of life for the treatment of neurological pathologies.

With a large number of positive effects, Actovegin has the disadvantages of high cost and side effects:

  • fluctuations in body temperature;
  • increased sweating;
  • disruption of the gastrointestinal tract;
  • tachycardia, heart pain;
  • urticaria symptoms;
  • development of Quincke's edema.

The appearance of adverse reactions requires discontinuation of the use of Actovegin and replacement with analogues. To do this, you must inform your doctor about the presence of negative effects.

What can replace the drug?

Most people cannot afford to purchase original products, and therefore they are interested in what can replace Actovegin.

The main substitute, which has a similar composition to Actovegin and is aimed at increasing cerebral circulation, is Solcoseryl, which causes acceleration of the cellular regenerative functions of tissue in various types of damage. It can be prescribed for symptoms of venous insufficiency, manifestations of dementia, skin lesions, trophic disorders and the consequences of traumatic brain injuries.

There are several types of substitutes that do not have a variety of release forms: Omaron is sold only in tablets, with rapid vascular expansion and neotropical properties.

Analogues of Actovegin in ampoules

Cortexin is a domestically produced product. It is represented by a complex of polypeptides obtained from cattle brain tissue. It has similar operating mechanisms and properties. Characterized by high insight. It has a restorative effect on the functional characteristics of the brain. Prescribed for the treatment of circulatory blood disorders of brain tissue, various encephalopathies, and cognitive disorders.

Cerebrolysin was created based on an extract of areas of the cerebral cortex of pigs. It is a nootropic that improves cellular energy metabolism, protein synthesis functions, and protects neurons from toxic amino acid effects.

Actovegin analogue in tablets

This drug has several generics: Curantil, Vero - Trimetazidine, Dipyridamole. In addition to improving blood circulation, the drugs have an effect on the immune system, increase interferon production and increase the body's defenses during viral infection.

Comparative characteristics

When comparing medicines, several properties that are characteristic of analogues can be identified:

  • Inability to use during pregnancy and breastfeeding.
  • Widely used for microcirculation disorders.
  • Variety of release forms.
  • Affordable pricing policy.

Main characteristics of Actovegin


The active element of the composition is blood extract purified from protein. 1 ml contains 0.4 g. dry matter. When taking Actovegin, cellular metabolism is activated and energy functioning is normalized. The instructions indicate diseases such as:

  • cerebral circulatory disorders;
  • ischemic stroke;
  • damage to peripheral blood circulation;
  • violation of skin trophism with varicose veins;
  • ulcers;
  • bedsores;
  • burns;
  • corneal damage;

Inability to use for pathologies:

  1. stage of decompensation of cardiovascular pathology;
  2. functional renal disorders;
  3. type 1 diabetes mellitus;
  4. acute pulmonary failure;
  5. allergic reactions to the components of the drug;
  6. The use of ophthalmic gel may cause scleral hyperemia and lacrimation.
  7. Forms of external use rarely cause burning, itching, or pain, which last from 10 to 40 minutes.

Actovegin and analogues are available in ampoules, tablets, and ointments. Self-cancellation and use of analogues without the permission of a doctor is unacceptable.

There are restrictions during pregnancy

Has restrictions when breastfeeding

Not suitable for children

Can be taken by older people

Has limitations for liver problems

Has limitations for kidney problems

Actovegin is a natural medicine based on extracts of peptides from the blood of young calves. The medication restores blood microcirculation, which helps replenish oxygen deficiency in the blood and fill tissue cells with it.

The biological product Actovegin is prescribed for the following diseases:

  • cerebral disorders of vascular etiology;
  • post-traumatic period of concussion or skull injury;
  • dementia;
  • neuronal failure;
  • in case of disorders of the peripheral blood flow of venous and arterial origin;
  • angiopathy of trophic etiology;
  • polyneuropathy of atherosclerotic and diabetic origin.

Actovegin is not prescribed for the treatment of patients with the following disorders and diseases in the body:

  • pulmonary and cerebral edema;
  • anuria and oliguria;
  • myocardial failure during the period of decompensation;
  • fluid retention in the body.

Mechanisms of action of Actovegin

Use Actovegin with caution when:

  • increased concentration of chlorine and sodium in the body;
  • during pregnancy and the lactation period, although there is no clinical evidence of danger in use, it is necessary to calculate all possible risks for the child.

The dosage of Actovegin is calculated as follows:

  • disturbance of blood flow in the cerebral arteries - 5-25 ml per day using a dropper or intravenously. Subsequently, the doctor may prescribe pills;
  • ischemic stroke, polyneuropathy of sclerotic and diabetic etiology - 50 ml by drip. It is necessary to combine treatment with the use of Actovegin gel;
  • trophic eczema and ulcers with atherosclerosis and diabetes - 10 ml into a vein together with a gel for the treatment of non-threatening tissues.

Actovegin tablets are prescribed individually, but the standard dosage is 1-2 tablets three times a day. Therapeutic course – up to 45 days.

Analogs are not always cheaper than the original drug; their price directly depends on the manufacturer and on the components included in the drug, but still more affordable drugs exist.

The drug is available in the form of tablets, injection solution and ointment. There are not so many analogues of Actovegin that would have an identical composition. The cost of analogues is not always lower than Actovegin, because prices depend on the country of origin of the substitute for the original medication. Only Russian medicines are cheaper than Actovegin.

The most famous substitute for Actovegin is Solcoseryl, which is made from hemoderivat. It is produced in the form of an ointment for external use, as well as in a solution for injections and tablets. The medication activates metabolism in damaged tissues and also stimulates the recovery process inside the fibers. Solcoseryl is prescribed for the following pathologies:

  • obliterating pathologies of the lower extremities;
  • angiopathy of diabetic origin;
  • insufficiency of the venous system.

Similar products in ampoules and tablets

Among the analogues of the drug are products that are presented as solutions and tablets.

is a cerebrovasodilator that restores functionality in parts of the brain and is a substitute for Actovegin in tablets. The drug restores blood microcirculation, which improves the flow of oxygen into the cerebral arteries. The active component vinpocetine stimulates the effect of norepinephrine and the hormone serotonin on metabolism in the cerebral organs (read also the drug). The medication does not affect myocardial contraction or blood pressure.

The drug is effectively used for the treatment of such cerebral pathologies in both hypertensive and hypotensive patients:

  • transient brain attacks;
  • encephalopathy of atherosclerotic origin;
  • memory loss and development of cephalgia;
  • tinnitus and deviations in the functionality of the hearing organ.

Instructions for use

It is prohibited to use the drug in patients with the following pathologies:

  • heart rhythm disturbance;
  • decreased tone of the arterial membranes;
  • unstable blood pressure readings.

Also, Cavinton is not used in the treatment of pregnant women and during lactation. For therapy, 1-2 tablets are prescribed orally three times a day. For maintenance therapeutic treatment – ​​1 tablet 3 times a day. Positive dynamics in treatment appear after 7-14 days of taking the medication.

The solution is used only by drip - 1 ampoule per 500 ml of sodium chloride. In case of severe development of the disease, droppers are prescribed three times a day. After the symptoms of the acute phase of the disease are relieved, the patient is transferred to treatment with tablets. For children, the drug is administered by drip in a glucose solution for 14-21 days, after which tablets are prescribed with a dosage of 0.5 mg per 1 kilogram of the child’s weight.

Pharmacological effects

Cavinton can provoke the following negative actions in the body:

  • arrhythmia;
  • dizziness and headache;
  • weakness of the body;
  • dyspeptic disorders.

Cavinton injections are prohibited from being administered intramuscularly.

Mexidol

The nootropic medication has a membrane-stabilizing effect and is available in tablets and ampoules. The medication reduces the development of hypoxia in brain cells and also has an antioxidant effect on neurons. Thanks to the effects of the medication, neurons become more resistant to oxygen deficiency, which was a consequence of impaired hemodynamics in the cerebral sections, and the following changes occur in the cerebral organs:

  • the protection of cell membranes to emotional stress and the effects of toxins increases;
  • with oxygen imbalance, the formation of foci of necrosis, which becomes the cause of ischemic stroke, decreases;
  • memory improves, as well as the patient’s intellectual abilities;
  • platelet aggregation decreases, which increases the speed of blood movement in the brain.

Anti-ischemic effect of Mexidol

A course of treatment with Mexidol is prescribed for the following diseases:

  • autonomic disorders;
  • insomnia or drowsiness;
  • decreased memory quality;
  • withdrawal syndrome;
  • dementia and epilepsy;
  • trauma to the skull and brain;
  • severe stress;
  • intoxication of the body with medications, poisons and ethanol;
  • acute phase of pancreatitis;
  • dyscirculatory encephalopathy.

Mexidol in ampoules is not prescribed in pediatrics, allergies to components in the composition of the medicine, during pregnancy and feeding a newborn with mother's milk. It is also prohibited to use the drug in patients with kidney and liver failure.

Treatment of severe forms of pathology begins with drip administration of a solution three times a day, 100 mg. The maximum permissible dosage per day is 800 mg. After acute symptoms are relieved, the patient is prescribed tablet therapy.

Analogue drugs in tablets

There are analogues of Actovegin, which are available only in tablet form.

Curantil is a myotropic vasodilator that is able to stop the aggregation of platelet molecules, which promotes better microcirculation in the brain, as well as in the peripheral parts of the bloodstream and in the myocardium. The main component in the drug is dipyridamole with a vasodilating effect.

The drug is prescribed for therapy, as well as as a preventive measure for the following diseases:

  • cerebral ischemia and stroke;
  • myocardial infarction and post-infarction period;
  • dyscirculatory encephalopathy;
  • stable and unstable angina;
  • impaired blood flow in the cerebral organs;
  • endarteritis;
  • impaired blood circulation in the placenta and its insufficiency;
  • after surgical treatment, in order to avoid the formation of thrombosis.

Features of the action of Curantil

It is prohibited to use Curantil in patients with the following pathologies:

  • hypotension;
  • collapse;
  • allergy to a medication;
  • kidney and myocardial failure;
  • acute phase of myocardial infarction;
  • bleeding of unknown etiology.

The use of medication during pregnancy requires great care in determining the dosage. Curantil is prescribed as a last resort, when there is a real threat of the development of intrauterine pathologies due to fetal hypoxia.

Dosage per day for patients over 12 years of age is 75-225 mg. The dosage should be divided into 3-6 administration procedures. The permissible dosage per day is 600 mg. After the patient's condition has stabilized, the dose should be reduced to 50 mg. Maintenance therapy should be carried out with a daily dosage of 25-50 mg.

When taking Curantil and anticoagulants together, the dosage should not exceed 75 mg per day. You can increase the effectiveness of the medicine if you take it correctly - no later than 60 minutes before eating.

The drug can be used over a long course of medication.

Negative actions do not occur often. The following reactions of the body to the medication are noted:

  • allergies - urticaria, skin rash and itching, Quincke's edema, dermatitis;
  • digestive tract - vomiting, severe diarrhea, pain in the epigastric and abdominal region;
  • CNS and heart - pain in the head, decreased blood pressure index, dizziness, bradycardia, arrhythmia.

is a nootropic medication based on peptide bioregulators from the brain substrate of young pigs. The medication has anticonvulsant and cerebroprotective effects and is an antioxidant.

Cortexin is prescribed to treat the following diseases:

  • viral neuroinfection;
  • disturbance in cerebral blood flow;
  • brain and skull injuries;
  • encephalopathy of various etiologies;
  • encephalomyelitis;
  • asthenic syndrome;
  • encephalitis;
  • epileptic seizures;
  • autonomic disorders;
  • deviations in child development;
  • memory loss;
  • decreased intellectual abilities;
  • delayed speech development in a child.

Mechanism of action

During pregnancy, it is not recommended to take Cortexin due to the lack of clinical safety indicators regarding the developing fetus. During lactation, a woman must transfer her child to artificial nutrition, and only after that can she begin therapy with this medication.

The medication is administered intramuscularly once a day. The solution is diluted with procaine or sodium chloride. For adults, the daily dosage is 10 mg of cortexin for 10-14 days, as well as the same dose for children weighing more than 20 kg. For children up to 20 kg, the dose is calculated according to weight - 0.5 mg per 1 kg of body weight. A repeat course can be carried out after 3-6 months.

When treating the acute phase of a stroke, 10 mg is prescribed twice a day for 10 days. After a 10-day break, the therapeutic course must be repeated.

Adverse reactions when using the drug occur very rarely and can manifest as allergic reactions - skin rashes, redness at the injection site, itching of the skin.

Most effective in ampoules

Cerebrolysin is a nootropic with an active component – ​​Cerebrolysin protein concentrate. The drug effectively protects the brain from the action of free radicals. Cerebrolysin prevents the death of neurons during the development of hypoxia. The protective properties of the drug are very important in the treatment of ischemic stroke caused by transient attacks and insufficient microcirculation in the cerebral arteries.

Cerebrolysin is prescribed for the following pathologies:

  • traumatic and age-related dementia;
  • brain and spinal cord injury;
  • ischemic stroke;
  • developmental delays in children, as well as lack of attentiveness;
  • Alzheimer's disease;
  • depression and stress;
  • memory loss;
  • cerebrovascular diseases.

Effects of Cerebrolysin

Cerebrolysin should not be prescribed for the following concomitant diseases:

  • epilepsy;
  • sensitivity to components;
  • kidney failure.

The drug does not exhibit toxicity, but it must be used with caution in the first trimester of pregnancy and during the lactation period. Cerebrolysin is prescribed if absolutely necessary.

Cerebrolysin injections are prescribed for injection into a vein by jet or drip, as well as for intramuscular use:

  1. The course of therapy with the drug is 10-20 days with daily administration of the medication.
  2. For brain injuries, ischemic stroke - daily dosage of 10-50 ml.
  3. For damage to the brain or spinal cord - 5-50 ml.
  4. When treating depression, the dosage per day is 5-30 ml.
  5. In pediatrics, dosages are used in accordance with the child’s weight - 0.1-0.2 ml per 1 kg of weight.

The medicine can be prescribed in long courses until a stable therapeutic effect is achieved. Adverse reactions are rare and can manifest themselves in digestive tract disorders - diarrhea or constipation, flatulence and nausea, stomach pain and vomiting, as well as allergic reactions - skin rashes, urticaria, dermatitis, Quincke's edema, blue discoloration or excessive pallor of the skin . Also, the patient’s blood pressure may drop sharply after the administration procedure.

Substitute in ointment form

A medication with the same therapeutic effect as Actovegin is produced in the form of an ointment for external use. The active components in Alantan Plus are allantoin and dexapanthenol.

Alantan Plus is a medication that accelerates wound healing. Dexapanthenol in the cell is converted into pantothenic acid and acts on the affected areas as a vitamin. Allantoin in the composition of the medication has an anti-inflammatory effect, and also stimulates the granulation of the layers of the epidermis and softens the skin.

The ointment is used to treat the following pathologies:

  • wounds, cuts;
  • phototherapy burns, sunburn;
  • keratosis of the skin on the feet and palms;
  • prevention of diaper rash in a newborn;
  • atopic dermatitis;
  • trophic ulcers;
  • eczema.

Alantan Plus

Women also use the ointment to care for their nipples during lactation (before feeding, thoroughly rinse the ointment from the breast). During pregnancy, Alantan Plus is prescribed only by a doctor. The drug should not be used in treatment if you are allergic to its components.

The ointment must be applied twice a day in a thin layer to the affected areas of the skin. Lubricate nipples after each feeding procedure, and you should also lubricate the newborn’s skin after changing diapers or diapers.

For dry skin, the ointment can be applied 3-4 times a day.

The drug rarely causes side effects, but there is still a possibility of their occurrence. The skin reacts to the medication as follows:

  • eczema;
  • irritation and rash;
  • erythema and urticaria.

Allergic reactions of the body to ointment:

  • Quincke's edema;
  • difficulty breathing;
  • pale skin;
  • a sharp drop in pressure;
  • cyanide in the lip area.

The digestive tract reacts to the use of ointment:

  • nausea with vomiting;
  • diarrhea.

Actovegin is a drug that stimulates metabolism in body tissues, improves their nutrition and accelerates regeneration mechanisms.

Characteristics of the drug

The product is available in such forms:

  1. A solution sold in ampoules and vials.
  2. Gel, cream and ointment.
  3. Dragee in blister packs.

Depending on the purpose of use, the doctor prescribes one or another type of medication administration.

The main active ingredient in Actovegin is deproteinized hemoderivate. This substance penetrates the human body and reaches target organs.

At the same time, glucose metabolism and energy production in the form of ATP molecules are accelerated in tissues. Increasing the energy supply of cells contributes to improving tissue nutrition and accelerating regeneration.

Thus, Actovegin is a drug that is widely used for rehabilitation carried out after many severe pathologies. These include:

  1. Disorders (ischemic attacks, strokes).
  2. Vascular pathologies – angiopathy.
  3. Brain damage.
  4. Varicose veins and accompanying pathological changes in the skin.
  5. Severe burns.
  6. Severe necrosis (consequences of radiation exposure, trophic ulcers).
  7. Damage (cornea, sclera).

Actovegin cannot be used for a number of diseases. These include:

  1. Allergy to components included in the medicine.
  2. Heart diseases.
  3. Diabetes mellitus.

Do not use the drug during pregnancy and lactation.

When using the product, some patients may experience side effects:

  1. Severe lacrimation, redness of the eyes and others.
  2. Hives.
  3. Increased sweating.
  4. Burning, itching and redness of the skin (when applied topically).
  5. In rare cases, fever, chills, and fever.

The price for 50 tablets in Russia is about 1,500 rubles, and in Ukraine – 600 UAH; the cost of 5 ampoules (5 ml each) in Russia is 550 rubles, and in Ukraine – 300 UAH.

Thus, Actovegin is a biogenic stimulant. The product has proven itself in the treatment of a wide range of pathologies.

Analogues of the drug

Many other drugs, which are cheaper, have a similar effect.

Solcoseryl

This drug is the most famous analogue of Actovegin.

It also contains deproteinized hemolysate, which is isolated from the blood of calves.

The drug belongs to the group of biogenic stimulants.

A wide range of ways to use the drug makes it convenient for patients. It could be:

  1. Gel or ointment in a 20 ml tube.
  2. Special eye gel for placing behind the edge of the eyelid, 5 ml.
  3. Solution for intravenous injections with a volume of 1-2 ml.
  4. Dental paste with adhesive properties.

Solcoseryl is a highly effective remedy for the treatment of a wide range of diseases. The active substance penetrates the tissues and stimulates energy synthesis processes in them. Due to this, metabolic activity increases, and rapid regeneration and repair processes are launched. The nutrition of the organ increases, due to which the therapeutic effect of the drug is achieved.

The drug is widely used for the following diseases:

  • trophic ulcers;
  • burns;
  • various skin injuries;
  • venous insufficiency;
  • cerebrovascular accidents;
  • dementia.

Solcoseryl is a product that almost similar to Actovegin in its action.

These drugs have an almost identical composition and can replace each other. It is worth noting that Solcoseryl is a cheap product, Therefore, it is still more profitable to choose it.

Chimes

Curantil is a drug that cannot be considered a direct analogue of Actovegin by mechanism of action.

The drug has a similar effect on cerebral circulation, but the medicinal effect is achieved through a different route.

Curantil belongs to the group of antiplatelet agents, that is, it prevents platelets from binding to each other.

Due to this, blood viscosity decreases and blood circulation in the brain is normalized.

The drug is widely used for:

  • brain damage;
  • encephalopathies.

The drug should not be prescribed to patients suffering from heart disease., as they may cause severe side effects.

Cortexin

Another indirect analogue of Actovegin- This is Cortexin.

This product is widely used for restoration of normal blood circulation in brain tissue. The drug acts on the cerebral cortex.

An additional positive effect of taking it is anticonvulsant effect, which is very important for patients with encephalopathies.

Cortexin stimulates human cognitive functions - improves memory and attention, increases sensitivity to stress.

Thus, Actovegin is an effective drug that belongs to the group of biogenic stimulants. A wide range of uses and specific composition make the product almost irreplaceable.

Its only direct analogue is the drug Solcoseryl. Drugs from other medicinal groups – Curantil and Cortexin – also have a similar effect on the human body.

Effective and affordable substitutes for tablets, Actovegin ampoules

Actovegin is an effective pharmaceutical product that carries out an effective metabolic process and regeneration at the cellular level. The drug is quite in demand among patients, but for some categories of people it is not suitable due to its relatively high cost. Let's consider which domestic and foreign pharmaceutical companies can offer affordable analogues at a more reasonable price.

Characteristics of action

The medication is able to activate metabolism in tissues, stimulating regeneration processes. In addition, the medicine increases oxygen consumption, helps increase tissue resistance to its low content, the process of energy metabolism and glucose consumption. The circulation and utilization of glucose improves along with increased oxygen consumption. This is exactly how Actovegin works for ailments that interfere with normal blood circulation. In addition, the medicine has a positive effect on the biochemical characteristics of granulation. During the action, the concentration of substances such as hydroxyproline, hemoglobin, and DNA macromolecules increases.

The effective effect of the drug is achieved no later than 30 minutes after use. Maximum effect – after 3 hours.

What does the drug help with?

Indications for use:

  • Vascular and metabolic disorders of the brain - head injury, poor blood saturation, dementia;
  • Various peripheral vascular problems (arterial and venous) and prevention of their consequences (trophic ulcers and destruction of the vascular wall);
  • Diabetic polyneuropathy.

Who does the ban on use apply to?

Contraindications:

Actovegin should not be used in treatment for those who cannot tolerate its constituent substances. It is not recommended for the treatment of patients with severe heart disease, pulmonary edema, a decrease in the amount of urine excreted by the renal system or its complete absence in the bladder, leading to the cessation of discharge from the urination channel. Women in pregnancy and during breastfeeding should also be careful.

Harmful events during therapy

In most therapeutic cases, the medicine was tolerated well. Clinical studies have shown that allergies in the form of rashes on the patient’s skin, a feeling of heat, and increased sweating are rare. Anaphylactic shock can be a severe but extremely rare phenomenon.

How much does Actovegin cost: price at the pharmacy

To purchase a reviewed medical product, you must obtain a prescription from a doctor. In pharmacies, the cost of Actovegin ampoules and tablets can reach 1,466 rubles (information source - apteka.ru, Moscow). Price may vary depending on region.

List of inexpensive Russian and imported synonyms

Analogs are cheaper than the drug Actovegin Apteka.ru price in rub. Piluli.ru price in rub.
Moscow St. Petersburg Moscow St. Petersburg
Solcoseryl (solution)923 944 798 777
Cortexin (bottles)781 804 768 746
Curantil (tablets)584 597 550 535
Noben (capsules)532 548 507 493
Dipyridamole (tablets)366 399 434 410
Divaza (tablets)333 347 318 289
(tab.)271 265 270 247
Omaron (tab.)129 163 128 124

Solcoseryl – (Switzerland)

An imported generic in the form of an injection solution effectively copes with venous and arterial insufficiency, which is accompanied by various trophic disorders, as well as failures of stable blood saturation of the brain.

It is prohibited for use only by those who do not assimilate the composition of Solcoseryl.

As a side effect, the patient may suffer a mild form of allergy - rash, swelling where the solution was injected.

Cortexin – (effective replacement of Russian production)

It is prescribed to overcome problems with blood saturation of the brain, treatment of acute and chronic encephalitis, VSD, epileptic seizures, head injury, neuroinfections of viral and bacterial origin, asthenia, problems with memory, and thought processes. Used for the treatment of children with cerebral palsy and unstable psychomotor and speech development.

The course of treatment does not cause severe side effects.

Kurantil – (Germany)

Do not take if you have a heart attack, hypotension, problems with the heart, liver, kidneys, hemorrhagic diathesis and a tendency to develop internal bleeding.

Parallel negative manifestations may include increased heart rate, diarrhea, vomiting, headaches, and skin rash.

Noben – (domestic generic)

Able to overcome any manifestations of psychoorganic syndrome provoked by disturbances in cerebral blood flow and changes in the brain due to old age. Noben is also competent to solve ailments associated with neurasthenia, injuries, which subsequently manifest themselves in the form of emotional disruptions, decreased intellectual ability, headaches, ringing in the ears and dizziness.

Do not use if there is excessive sensitivity to the composition of the product or kidney pathologies. For women in the position and period of breastfeeding, Noben is recommended only after qualified medical consultation.

As therapy progresses, in extremely rare situations, problems with falling asleep, increased emotional and mental excitability, headaches and allergies are possible.

Dipyridamole – (a worthy analogue produced in the Russian Federation)

The competence of this pharmacological agent is therapy and measures to prevent the development of problems with cerebral circulation. Dipyridamole also prevents the occurrence and development of diseases such as arterial and venous thrombosis with further complications. It is used during the rehabilitation stage after installation of a prosthetic heart valve. Women preparing to become mothers with difficult pregnancy may also benefit from taking this medication to prevent placental insufficiency.

It is distinguished by the presence of a wide list of prohibitions for use. Cannot be used in cases of exacerbation of heart disease, angina pectoris, atherosclerosis of the arteries, high or low blood pressure, a tendency to bleeding due to concomitant diseases, liver or kidney pathologies. In addition, it is not recommended during breastfeeding and for children under twelve years of age.

A large number of undesirable manifestations during the therapeutic process. First of all, the heart and central nervous system are at risk. Problems with the system responsible for digestive processes are possible - gag reflexes, abdominal discomfort, diarrhea. However, such manifestations are only possible during a long course of treatment.

Divaza – (Russia)

A high-quality medicine aimed at comprehensive treatment and ensuring the recovery process of brain activity against the background of disorders of the central nervous system of an organic nature, including ischemic and neurodegenerative diseases and traumatic brain injuries.

Use is not permitted in case of a negative reaction of the patient’s body to the components of the pharmaceutical product and by minors.

Divaza does not have many associated harmful effects. As a rule, the patient may experience only hypersensitivity reactions.

Mexidol – (well-known Russian substitute)

It fights well against the consequences of acute cerebral circulatory disorders, mild traumatic brain injury, encephalopathy of any origin, VSD. In addition, Mexidol overcomes feelings of excessive anxiety and neurotic conditions that arise due to stress. Can be prescribed to relieve withdrawal symptoms (when drinking alcohol).

This medicine is not prescribed for complex kidney or liver diseases, children, women preparing for childbirth and breastfeeding.

At the same time, in rare cases, the treatment process can lead to a deterioration in the general condition in the form of nausea, a feeling of dryness in the mouth, as well as allergic reactions.

Omaron – (the cheapest analogue of domestic production)

Despite its cost, it has similar indications to the substitutes discussed above. Omaron is able to collectively treat a lack of blood saturation in the brain, the period of encephalopathy after intoxication or injury. In addition, it is indicated in the presence of vestibular disorders (including motion sickness) and depressive states. Prophylactic use is allowed to prevent migraines.

Not intended for the treatment of patients with unstable functioning of the hepatic or renal system, hemorrhagic stroke. It is also contraindicated for children under 5 years of age, women expecting a child and those in the lactation period.

Harmful parallel reactions may occur. The nervous system may be affected - there is a feeling of excessive tension, irritability, depression, headaches, and a desire to sleep. In addition, blood pressure may decrease or increase, problems with digestive processes may begin - a craving for vomiting, frequent bowel movements with weak stools. The skin may become covered with a rash, which will mean poor tolerance to the composition of the medication.

Conclusion on low-cost generics

The product from an Austrian manufacturer has a significantly different price tag, in contrast to analogues available on the pharmaceutical market. Substitutes are produced by imported and domestic factories and have a lower price. However, almost each of the generics has its own peculiarity.

Actovegin is a natural drug that affects metabolic processes in the body. The active ingredient of the drug is a natural component obtained from calf blood extract purified from protein.

Most often this drug is used in neurology, psychiatry and cardiology.

Can be used as an adjuvant treatment in ophthalmology, dermatology and other fields.

Has a wide spectrum of action:

  • accelerates metabolism at the cellular level;
  • improves blood microcirculation;
  • has an antioxidant effect;
  • accelerates the processes of healing and tissue restoration;
  • eliminates the consequences and increases the resistance of cells to oxygen starvation.

Actovegin is in the form and is used for cognitive disorders, after surgical interventions, and for decreased vascular tone.

Gel and ointment are used for skin disorders, dermatological diseases, wounds, burns.

Advantages and disadvantages of the product

The undoubted advantage of the drug is its natural composition. In the absence of contraindications, this remedy can be used without harm to both the mother and the fetus. Often used to treat childhood neurological diseases. The natural composition of the drug allows it to be used from the first days of a baby’s life. Another big plus is that Actovegin combines well with other medications.

There are contraindications to the use of Actovegin, but they are extremely few, namely: pulmonary edema, heart failure, some kidney diseases, fluid retention in the body. In addition, this medicine should not be used if you are hypersensitive to the components of the drug.

Despite the fact that Actovegin is well tolerated, side effects may occur:

  • increased temperature and sweating;
  • gastrointestinal upset, stomach pain, diarrhea;
  • tachycardia, heart pain;
  • urticaria, Quincke's edema.

If such reactions occur, the use of Actovegin should be discontinued and replaced with another drug of similar action.

In addition to contraindications and side effects, the disadvantage is the price of the drug; if it is impossible to use Actovegin due to its high cost, you should ask your doctor to look for cheaper analogues, since there are plenty of them now.

What can replace the drug?

If necessary, Actovegin is replaced with drugs equivalent in therapeutic effect, they are called analogues or generics.

It should be remembered that replacing one drug with another should only be done with the permission of the attending physician.

TOP 10 best, in our opinion, analogues of the drug Actovegin:

Tablet analogues

All Actovegin analogues in tablets differ in pharmacological group and active substance. But if the question still arises about replacing Actovegin tablets with another drug, you should pay attention to the following medications:

Injection analogues

Thanks to the active substance identical in composition, only Solcoseryl is a full-fledged analogue of Actovegin in the form of ampoules.

But if intolerance to the components of the drug occurs, it is necessary to select another drug that is similar in its effect on the body.

Actovegin in ampoules can replace the following drugs:

  • Cortexin;
  • Mexidol;
  • Elkar in ampoules;
  • Cerebrum Compositum N;
  • Picamilon.

Domestic analogues of the drug are: Piracetam, Cinnarizine, Omaron, Dipyridamole, Ginkoum, Vinpocetine. These drugs are the cheapest domestic analogues of Actovegin.

Despite the fact that almost any medicine can be purchased at a pharmacy without a doctor's prescription, you should not self-medicate. Only the attending physician will competently select the necessary medicine, calculate the dosage and duration of administration.

Comparative characteristics

We compared Actovegin and its popular analogues (Solcoseryl, Cerebrolysin, Cortexin, Mexidol and others), analyzed the indications, side effects, price and other indicators, and it is up to you to conclude what is best to take.