To treat coughing attacks with sputum that is difficult to clear, ACC is used. Even pus can be liquefied with this medicine. Available in various forms. It is worth studying in detail how ACC is used for cough; the instructions for use of the drug give precise instructions on how to dose the medicine.

Composition and properties

ACC, or ACC, is a medicine with mucolytic and expectorant properties. Thanks to its use, viscous mucus is liquefied and expelled more quickly. This drug is used as a therapeutic agent for diseases of the respiratory system. What cough is it used for? The medicine is effective for wet cough.

Medicines in the ACC series are produced by the Slovenian company Sandoz or the German company Hexal AG. Any of them can be purchased at a pharmacy without a doctor's prescription.

• effervescent tablets 100 mg, 200 mg, 600 mg;
• disposable bags of granules (powder);
• syrup for children;
• injection solution.

Effervescent tablets are white, round and flat. Dissolves very quickly in water. The result is a clear drink. Children are treated with tablets of 100 mg, and effervescent preparations of 600 mg are used by adults. A cardboard package usually contains 10 pieces.

The composition of effervescent products includes the main active ingredient – ​​acetylcysteine ​​and excipients. The most acetylcysteine ​​is contained in 600 mg tablets, which is why they are called ACC Long.

Granules or powder for preparing a warm drink are in disposable bags. The weight of one package is only 3 g. The powder is dissolved in warm water and you get a drink with the taste of lemon, orange or honey. The standard package contains 6 or 20 sachets.

The syrup is mainly used to treat children, but adults can also use it if desired. 1 ml contains 20 mg of active substance. The medicine is a viscous, thick liquid with a cherry flavor. Does not contain ethyl alcohol and dyes. The syrup includes additional components - caramelose, cherry flavor, saccharin, methyl parahydroxybenzoate, disodium edetate. In pharmacies it is sold in dark glass bottles of 100 or 200 ml. The kit includes a 10 ml measuring cap and a 5 ml syringe.

ACC solution for injection is used for inhalation or intravenously. The active substance is acetylcysteine. The transparent, colorless liquid is in ampoules, in one package there are 5 pieces of 300 mg each. The medicine is used in intensive care units only if the use of tablets is not possible.

Pharmacological action

Acetylcysteine ​​has antioxidant and pneumoprotective properties and acts as an antidote for acute poisoning with paracetamol, as well as aldehydes and phenols. When taken orally, it is completely absorbed, and after 1–3 hours the maximum concentration of the active component in the blood is observed. It is excreted from the body in urine and feces. The medicine passes through the placenta, which is why it can accumulate in the amniotic fluid.

Indications

The medicine is effective for diseases of the respiratory system, when viscous, difficult to separate mucus is formed. ACC differs from other mucolytics in its high efficiency. The drug directly affects the sputum that has already formed, diluting it.

The main purpose of using ACC is to reduce the viscosity of sputum. It is used if the patient has a thick cough and the sputum is difficult to clear. With bronchitis, night cough decreases. However, after 18 hours the medicine cannot be given. If you take ACC for cough right before bed, the mucus will liquefy, which will cause coughing attacks.

For nasopharyngitis, the medicine will not relieve the patient of sputum. The viscosity may decrease, but the production of mucus in the nasopharynx will not stop. In this case, complex treatment is needed. ACC is used for infectious and non-infectious diseases of the bronchopulmonary system.

It is advisable to use when:

• bronchitis;
• cystic fibrosis;
• bronchial asthma;
• pneumonia;
• otitis;
• sinusitis;
• bronchiecstasis;
• bronchiolitis.

Important! ACC is prescribed as a cough suppressant only when there is already mucus in the bronchi.

Instructions for use

The dosage of the medication depends on the form of release and the amount of the main active ingredient. Adults and children are prescribed different amounts of medication. The instructions included in each package of the drug help you determine the dosage.

Directions for use for adults:

• effervescent preparations: ACC 200 three times a day, ACC 600, like ACC Long, once a day;
• granules (powder): one sachet (200 mg) or 2 sachets (100 mg) three times a day;
• syrup: 10 ml three times a day.

More than 600 mg of medication should not be used per day. Treatment with the drug should be carried out for one week.

Dosage for children:

• syrup: from 2 to 5 years, 5 ml - 2-3 times a day, and from 6 to 14 years, 5 ml three times or 10 ml twice a day;
• effervescent preparations: from 2 to 5 years, one tablet (ACC 100) 2 or 3 times a day, and from 6 to 14 years, one tablet (200 mg) twice or one tablet (100 mg) three times a day;
• granules (powder): from 2 to 5 years, one sachet (100 mg) - 2 or 3 times a day, and from 6 to 14 years, one sachet (200 mg) 2 times or one sachet (100 mg) three times a day.

At what age should children be given syrup? You can treat your baby with this remedy from the age of 2 years.

The duration of treatment for children is no more than 5 days. The maximum effect of taking the drug occurs on the 3rd day. The final dose is prescribed only by the pediatrician. Children's ACC is taken after meals. Additionally, it is recommended to drink a lot of liquid (herbal tea, juice, dried fruit compote). It is better to give the child syrup, and if he does not like the taste of cherries, you can give the powder, it resembles an orange.

How to take

Effervescent preparations are dissolved in warm water. The solution is prepared immediately before use. For 100 mg of the drug you need 100 ml of liquid. Granules (ACC powder) are dissolved in warm water. To do this, take a glass of liquid and pour a bag of medicine into it, mix everything and drink. The glass must be made of glass; metal utensils must not be used.

The syrup is drawn into a measuring syringe and directed not into the throat, but into the cheek area, otherwise the baby may choke. You can only draw up the medicine with a syringe, and then pour it into a spoon and thus give it to the child. The syrup is not mixed with water, but it can be washed down with tea or juice.

Important! The medicine is not prescribed for children under 2 years of age. The dosage for such babies is not indicated in the instructions, as there are a number of contraindications. If you give medicine to a child under 2 years of age without the instructions of a pediatrician, he may suffocate.

Overdose

Exceeding the daily dose of the drug does not cause intoxication. However, in case of an overdose, the patient may experience nausea, sometimes even vomiting, and gastrointestinal upset. In this case, an antidote is not needed; treatment is symptomatic.

Contraindications

ACC is not used:

• with ulcers;
• with hepatitis;
• during pregnancy and lactation;
• children under 2 years old;
• with liver failure;
• if there is hypersensitivity to the active component;
• with bleeding from the lungs;
• if you have fructose intolerance.

Important! The medicine should be prescribed with caution to patients with bronchial asthma; care must be taken to ensure that bronchospasm does not occur. People with diabetes should take into account that the drug contains sucrose. ACC Long is prescribed only to children over 14 years of age.

Adverse reactions

ACC and adverse reactions:

• nausea;
• stomatitis;
• vomit;
• gastrointestinal problems;
• hives;
• tinnitus;
• bronchospasm;
• headache;

Problems with the cardiovascular system in the form of increased blood pressure and arrhythmia may also occur.

Interaction with other drugs

ACC should not be used together with cough suppressants. If the reflex contraction of the bronchi is suppressed, this can lead to stagnation of mucus in them. It should not be used with oral antibiotics. The interaction of these drugs results in a decrease in the effectiveness of both. An interval of 2 hours should be maintained between doses. True, there are exceptions to this rule: the antibiotics Loracarbef and Cefixime.

Analogs

ACC costs from 150 to 650 rubles, depending on the type. So, for example, the price of syrup for children is 300 rubles, Long effervescent preparations cost 500 rubles, and sachets cost 150 rubles. If ACC is not suitable for some reason, you can purchase other cough medicines for children - for example, Bromhexine. It costs about 170 rubles. The medicine copes well with coughs, and its list of contraindications is much smaller. There are other analogues in syrups: Lazolvan, Flavamed, Ambrobene.

Ascoril can be used to treat cough. The drug relieves spasms in the bronchi and has a strong mucolytic effect. Fluimucil can also be used as a drug that thins phlegm in the bronchi.

Acetylcystine is a domestic analogue of ACC. It has the same effect, but costs about 130 rubles. The drug is produced in the form of granules, powders and in the form of effervescent tablets. In addition, analogues of ACC are: Acestine, Mukobene, Mucomist. The selection of an analogue is carried out by a doctor.

ACC is suitable if you need to cope with phlegm that is already present in the bronchi. The medicine is used to treat both adults and children. It is used only as prescribed by a doctor, although you can buy it at the pharmacy without a prescription. You should not self-medicate, because you need to correctly determine the nature of the cough.

Medicines of the ACC group, created on the basis of acetylcysteine, have actively entered into treatment practice. One of them, ACC 100, the instructions recommend for use for children. The number on the package indicates the dosage of the active substance. It corresponds to the minimum single dose for a child.

Release forms and composition

ACC 100 is produced by the Austrian company Hermes Pharma Gas, Sandoz Slovenia, Salutas Pharma GmbH Germany in the form of effervescent tablets or powder with blackberry flavor. Children drink this medicine with pleasure.

One aluminum tube contains 20 tablets or powders containing 100 mg of acetylcysteine.

The composition of the tablet and powder, according to the instructions, includes 100 mg of acetylcysteine, soda, mannitol, citric and ascorbic acid, blackberry flavor, sucrose.

The inclusion of soda in the composition makes the use of ACC 100 dangerous if a cough occurs in a patient with a sore stomach. And sucrose will require an increase in the dose of insulin for a patient with diabetes.

Acetylcysteine ​​is the active ingredient of the drug.

Mechanism of action of ACC

The instructions classify the drug as a mucolytic agent. This means that it is capable of diluting phlegm, mucus, and pus. Studies have shown the effectiveness of acetylcysteine ​​in three areas:

• liquefaction of thick secretions due to the rupture of the molecular bonds of the mucosaccharides that make up the mucus;
• stimulation of local immunity through phagocyte cells;
• antioxidant effect as an element in the fight against inflammation.

The effect is maximal within an hour after ingestion and lasts up to eight hours. ACC 100 decomposes in the liver and is excreted mainly in the urine.

Indications for use

The instructions recommend the use of ACC 100 for children and adults for diseases associated with increased formation of mucus, sputum, and pus. Such diseases are: bronchitis, laryngotracheitis, sinusitis, inflammation of the middle ear, bronchial asthma, cystic fibrosis.

Adverse reactions rarely occur in the form of skin rashes, nausea, headache, dyspepsia, stomatitis. Patients with bronchial asthma may experience an attack of bronchospasm.

Absolute contraindications for ACC 100 are:

• lung diseases accompanied by hemoptysis;
• peptic ulcer of the stomach and duodenum;
• individual intolerance to components.

• for children under two years old;
• during pregnancy and lactation;
• for chronic liver and kidney diseases.

Dosage

The dosage and course of treatment with the drug are prescribed by the attending physician. It depends on the severity of the condition, the patient’s weight, and concomitant diseases.

An effervescent tablet or powder, according to the instructions, must be dissolved in half a glass of water, tea or juice before use. Drink after eating.

The solution should be prepared only in glass containers. Upon contact with metal and rubber, acetylcysteine ​​is deactivated. The prepared drink should not be stored for longer than two hours.

ACC 100 should not be taken simultaneously with antibiotics such as penicillin, ampicillin, erythromycin, tetracycline, or antitussives. Because it reduces their effect. At least two hours should pass between ingestion of the antibiotic and ACC 100.

The tube with ACC 100 tablets must be closed quickly, because acetylcysteine ​​partially decomposes in air.

Before starting treatment, carefully read the instructions and how to prepare the drink. Any unexpected reactions to a medication should be reported to your doctor.

"ASS" for cough: instructions for use. "ACC 200": reviews, price

Quite often, doctors prescribe the drug “ACC” (“ACC”) for cough to their patients. Instructions for the use of this remedy, as well as its contraindications, indications and side effects will be presented in this article. In addition, we will tell you about the form in which the mentioned medicine is produced, what patients say about it, how much it costs, and so on.

Packaging of the drug, its release form, composition

Do you know in what form the medicine “ACC” (“ACC”) for cough is produced? The instructions for use inform us that this drug is produced in two different forms. Let's look at them in more detail:

• Medicine "ACC" is a powder (granulated) intended for the preparation of a solution. This medicine should only be taken orally. One 3-gram sachet of powder can contain 200, 100 or 600 mg of acetylcysteine. There are 10, 6 or 20 sachets in a cardboard pack.
• The drug "ASS" - effervescent tablets. Aluminum or cardboard tubes can contain 20, 10, 100 or 50 pieces. One tablet contains 600, 200 or 100 mg of acetylcysteine. As for the auxiliary components, these include citric anhydride, sodium bicarbonate, ascorbic acid, mannitol, lactose anhydride, sodium citrate, blackberry flavor and saccharin.

Pharmacological action of the drug

What is “ACC” (“ACC”) cough medicine? The instructions for use state that this is a mucolytic drug. Due to the fact that the structure of the acetylcysteine ​​molecule contains sulfhydryl groups, this causes the rupture of disulfide bonds of mucopolysaccharides (acidic) of sputum. As a result of this effect, the patient's mucus viscosity noticeably decreases.

The drug in question has a mucolytic effect and also facilitates the discharge of sputum due to a direct effect on its rheological properties. This remedy retains its activity even in the presence of purulent mucus.

The ACC medicine, the instructions for which are presented below, is very often used for preventive purposes. In this case, there is a decrease in the severity and frequency of exacerbations in patients with cystic fibrosis and chronic bronchitis.

Pharmacokinetics of the drug

What pharmacokinetic properties does the drug "ACC" have? The instructions do not contain such information. This is due to the fact that pharmacokinetic studies of this medication have not been conducted.

Drug "ACC": indications

The drug in question is prescribed for the following deviations:

• acute and chronic sinusitis;
• diseases of the respiratory system, which are accompanied by the formation of difficult to separate and viscous sputum (for example, with bronchiectasis, acute and chronic bronchitis, cystic fibrosis, obstructive bronchitis, pneumonia, bronchial asthma and bronchiolitis);
• otitis media.

Contraindications

In the presence of what abnormalities should the medicine "ACC" (powder and effervescent tablets) not be prescribed? The following conditions are contraindications to the use of this drug:

It should also be noted that this medication is prescribed with extreme caution to patients with varicose veins of the esophagus, diseases of the adrenal glands, renal and/or liver failure.

Directions for use

How should you take ACC for cough? The instructions for use contain the following instructions in this regard. For adolescents and adults, it is prescribed 200 mg three times a day. Children from 6 to 14 years old should take the medicine 100 mg three times a day. For children from 2 to 5 years old, the medication is prescribed 1 tablet (100 mg) twice a day. For a disorder such as cystic fibrosis, a child over 6 years of age is given 2 tablets of the drug (100 mg each) three times a day. As for children from 2 to 6 years old, they should take the medication 100 mg four times a day.

For patients with cystic fibrosis weighing more than 30 kg, the dosage can be increased to 800 mg per day.

For colds of a short-term nature, the duration of therapy with the presented medication is 5-7 days. For cystic fibrosis and chronic bronchitis, the drug must be used for a longer time (to prevent infections).

How should I take ACC 200? The instructions state that this drug should be used only after meals (to avoid negative effects on the gastric mucosa). It should be especially noted that additional fluid intake enhances the mucolytic effect of the drug.

Before use, effervescent tablets must be dissolved in half a glass of plain water. The prepared solution should be used immediately. In exceptional cases, it can be left for 2 hours.

Overdose

In case of intentional or mistaken overdose of the drug, the patient experiences symptoms such as vomiting, stomach pain, diarrhea, heartburn and nausea. To date, no severe or life-threatening side effects have been observed.

Drug interactions

What happens if you take any medications and ACC at the same time? Reviews from experts say that combined treatment can cause a number of undesirable reactions. Let's look at them a little further.

With the simultaneous use of acetylcysteine ​​and other antitussive drugs, a stagnation of mucus that is dangerous to health may occur (due to suppression of the cough reflex).

During the simultaneous use of nitroglycerin and acetylcysteine, there is a possibility of enhancing the vasodilating effect of the former.

There is a synergism of acetylcysteine ​​with the simultaneous use of bronchodilators.

Acetylcysteine ​​can reduce the absorption of penicillins, cephalosporins and tetracycline. In this regard, they must be taken orally 2 hours after taking the first one.

Acetylcysteine ​​is not compatible with antibiotics such as Penicillin, Erythromycin, Cephalosporin, Tetracycline and Amphotericin, as well as proteolytic enzymes.

When acetylcysteine ​​comes into contact with rubber and metal, sulfides are formed, which have a characteristic odor.

Special instructions

For obstructive bronchitis and bronchial asthma, the drug in question should be prescribed with extreme caution. This requires systematic monitoring of bronchial patency.

If, after taking the medication, the patient develops side effects, then it is necessary to stop taking the medication and immediately consult a doctor.

When treating patients with diabetes mellitus, it should be taken into account that 1 effervescent tablet corresponds to 0.006 XE.

To date, there is no information about the negative impact of the drug (in recommended dosages) on the ability to drive a car, as well as perform other activities that require special concentration.

Shelf life and storage methods

The drug in question must be stored only in a dry place inaccessible to small children. In this case, the air temperature should not be higher than 25 °C. The shelf life of the drug is three years. After this time, the use of the medication is prohibited.

After taking the effervescent tablet, the plastic or aluminum tube must be tightly closed.

Price and analogues of the drug

The price of the ACC tablet may vary depending on the pharmacy chain, as well as on the markup on the product. However, on average, such a medicine costs about 75-150 Russian rubles. The price of granular powder is similar to effervescent tablets.

What can replace the product in question? Pharmacy chains have a huge number of analogues of the drug, as well as drugs with a similar effect (expectorant, mucolytic). Among the most popular, I would like to highlight the following medications: “Acestine”, “Acetylcysteine”, “Vicks Active ExpectoMed”, “Mukobene”, “Mukomist”, “Mukonex”, “N-AC-Ratiopharm”, “Fluimucil”, “Exomyuk 200” , "Atsestad", "Lazolvan", "Ambrobene", "Ambroxol", "Mukosol", "Bronkatar", "Solvin", "Bromhexin", "Gedelix", "Mukaltin", "Prospan", "Stoptussin", " Askoril", "Linkas" and others.

Patient reviews of the medication

Now you know what analogues of the drug “ACC” are available and what its price is. Tablets and powder for preparing the solution cope quite effectively with the task. This is the opinion that most patients hold. The drug quickly treats acute and chronic sinusitis, as well as other respiratory diseases. Thanks to it, viscous and difficult to separate sputum easily moves away from the bronchi, significantly improving the condition of the sick person.

It should also be noted that the product in question is not only highly effective, but also relatively inexpensive. This fact is very pleasing to patients who cannot afford to purchase expensive medications.

ACC for cough: instructions for use and dosage

For children, if it is difficult for them to separate sputum, as well as with a wet cough, ACC is prescribed for cough. Instructions for use and dosage of the drug are described below in the article.

ACC for cough - instructions for use and rules of administration

The drug ACC is produced in several forms, namely two. The first of them is granules in a bag. A solution of ACC 100 is prepared from them. The second is produced in a bottle and syrup is prepared. The second type has appeared on the market. It is more preferable for children aged ten days to two years. Although the active chemicals are exactly the same.

Yandex.Direct

ACC for cough for children is prescribed by a doctor if they have a wet cough. That is, when viscous mucus forms in the bronchi, and it is not able to leave on its own. ACC for cough instructions for use indicate the following indications:

1. presence of acute or chronic bronchitis;

2. bronchiolitis;

3. obstructive bronchitis;

4. bronchial asthma;

7. pneumonia;

8. chronic or acute sinusitis;

9. chronic obstructive pulmonary disease;

10. preventive treatment after complications during operations;

11. paracetamol poisoning.

Pharmacological groups of the drug ACC - a detoxification agent (contains antidotes). Stimulates the motor function of the respiratory tract.

ACC for cough - dosage for use

Application and dosage of ACC: infants from the 10th day of life and children under two years old take 2.5 ml of syrup. Or acetylcysteine ​​fifty mg two to three times a day (daily dose one hundred and fifty mg). Children from two to six years old - 5 ml of syrup or (acetylcysteine ​​one hundred mg 2-3 times a day, three hundred mg per day); children from six to fourteen years old - 5 ml or (acetylcysteine ​​two hundred mg 2-3 times a day, four hundred mg). Make sure your child takes plenty of fluids throughout the day. The last dose of medication should be no later than four hours before bedtime.

The course of treatment is from five to seven days. In severe forms, the course of treatment for ACC for cough is determined by the doctor. ACC syrup is designed for 1 course of treatment.

Side effects of ACC: possible nausea, heartburn, vomiting, noise or ringing in the ears, urticaria.

"ACC" for children (syrup): instructions for use, reviews

When a child falls ill in the family, all the attention of adults focuses on him. And the point here is not whether it is a serious illness or a cold with a cough. Moreover, in fact, cough itself is a symptom of the disease and requires treatment.

To combat this problem, a wide variety of medicines have been developed in a variety of forms: tablets, suspensions, inhalation formulations, cough syrup. “ACC” for children was developed by manufacturers in Germany and Slovenia. The main functions of this drug are to liquefy difficult-to-separate mucus and facilitate the process of removing it from the respiratory tract. "ACC" has an anti-inflammatory effect, suppressing pathogens that develop in sputum.

Operating principle of "ACC"

For the stable functioning of the human body, nature has arranged everything in such a way that a special mucous secretion is constantly produced in the respiratory tract, the main functions of which include protective, cleansing and antibacterial effects. If a person gets sick, the process of producing this secretion is activated many times over. The consistency of this mucus has increased viscosity: the child suffers from prolonged coughing attacks, suffocates, and the sputum does not come out. This cough is called non-productive.

It is in such cases that “ACC” for children (syrup) is prescribed to help the child’s body. Instructions for use allow it to be prescribed to children from the age of two. The viscosity of sputum directly depends on the presence of special bonds in it - disulfide bridges. "ACC", entering the child's body, affects these connections and contributes to their rupture. The sputum becomes less viscous, and the process of removing it from the respiratory tract is greatly facilitated. Air masses entering the bronchi are able to circulate freely without causing irritation to the nerve endings. The cough becomes productive.

"ACC" (syrup for children) continues to remain active even in cases where there is a purulent component in the sputum. At first, parents may feel that the cough has gotten worse. However, the intensification of this process only indicates that the drug is working. Gradually the cough reflex fades, and soon the cough goes away completely.

The antioxidant properties of "ACC" are able to suppress local inflammatory processes, which practically eliminates the likelihood of relapses and complications. The medication has no effect on the immune system.

Possible release forms

Manufacturers, for convenience and breadth of use, offer the drug in several release forms. The granules in the bottle are diluted with water on their own to form an “ACC” syrup. Instructions for use for children often allow even children who have not yet reached the age of two to be treated with this medicine. True, doctors do not practice prescribing it to newborns for the treatment of cough and bronchitis for the reason that the airways of infants are very narrow and the pectoral muscles are still weak. For these reasons, a small child simply will not be able to cough up the increased volume of sputum. If there is no alternative to this medication, then treatment with ACC should be carried out under the supervision of the treating doctor.

However, it should be noted that “ACC” (syrup) instructions for use for children under one year old allows it to be prescribed if the child has cystic fibrosis (a hereditary disease characterized by impaired functioning of the respiratory system).

Effervescent tablets "ACC" are widely used. They can be purchased in three dosages: 100, 200 and 600 mg of acetylcysteine ​​(the main active ingredient). A dose of 600 mg bears the trade name “ACC-Long”, is characterized by a prolonged effect and is prescribed to patients at least 14 years of age. One tablet of this medication, taken once, replaces several smaller doses.

The suspension is prepared by diluting granules from sachets (100, 200 mg) in water, tea, milk or juice. The resulting composition should not be hot. Ideally, its temperature is close to body temperature.

With the use of "ACC" it is even possible to do inhalations. 1-2 ml of a solution intended for injection (used in very severe cases in a hospital setting under the supervision of a physician) is mixed with an isotonic sodium chloride solution and used in special inhalers or nebulizers. Procedures can be performed 1-2 times a day. The course of therapy is up to 10 days.

Indications for use

The indications for which this drug can be prescribed are quite wide. As for small patients, a special dosage has been developed for them, called “ACC 100”. Instructions for children: syrup (as the optimal form for treating even infants and children under 2 years old) can be used for a number of diseases of the respiratory system.

In general, “ACC” is prescribed to patients suffering from bronchitis (any form: chronic, acute, obstructive), pneumonia, tracheitis, broncholitis (inflammatory processes of the lower respiratory tract), cystic fibrosis. The medication is used for bronchiectasis (an increase in the diameter of the bronchi in the place where the bronchial wall is damaged).

It is also practiced to prescribe "ACC" in the treatment of otitis and sinusitis (acute, chronic form), since the drug is able to dilute not only sputum, but also accumulations of pus, stimulating its excretion from the body.

Contraindications for taking "ACC"

"ACC" for children (syrup) instructions for use prohibits use by patients with individual intolerance to the components of the medication and those who suffer from gastric and duodenal ulcers (acute stage). The same diseases, but in remission, can also respond to the use of ACC. Therefore, patients with such problems should be attentive to their well-being.

With great precautions, "ACC" (syrup for children) should be taken by patients with kidney and liver failure, problems with the adrenal glands, and bronchial asthma.

Since many diseases have become younger today, even young children can encounter gastrointestinal ulcers or diabetes mellitus. With the latter disease, it must be borne in mind that “ACC” contains sucrose. If a child is diagnosed with phenylketonuria, then for the treatment of cough it is necessary to choose “ACC”, which does not include aspartame (sweetener).

Contraindication for "ACC Long" is a child under 14 years of age.

Directions for use and dosage

Instructions for use of "ACC 100" syrup for children are recommended for use when the patient's age is from 2 to 5 years. It can also be granules in sachets (volume - 100 mg), which are taken 2-3 times a day. Another option is granules in a bottle for making syrup, which is indicated for taking 5 ml (1 measuring spoon) also 2-3 times during the day after meals.

Patients in the age group from 6 to 14 years old are prescribed ACC 200 mg (granules in bags) twice a day or 2 scoops (10 ml) of syrup twice a day with meals.

For patients over 14 years of age, it is practiced to prescribe "ACC" 2 scoops (10 mg) 2-3 times a day (or use "ACC Long").

In the most extreme cases, the instructions for use for children up to one year allow the use of “ACC” (syrup). Reviews from doctors in this case indicate an underdeveloped respiratory system and weak pectoral muscles. A small child may have difficulty coughing up the increased volume of mucus.

It is worth saying that the standard treatment regimen is described above. In some particularly severe cases, the dosage of the drug can be adjusted upward (or decreased, if the situation is not very severe). The usual course of treatment is up to 7 days. Only the doctor can decide to increase the treatment period. In chronic forms of bronchitis or cystic fibrosis, the course of therapy using ACC can last for several months. In parallel with this, constant monitoring of the functioning of the liver, kidneys, and adrenal glands is carried out. Blood enzyme levels are also subject to monitoring.

Possible side effects

The drug "ACC" causes side effects quite rarely. Parents of young patients talk about the appearance of headaches, the development of stomatitis, and tinnitus. Deviations in the functioning of the gastrointestinal tract, such as nausea, vomiting, and diarrhea, occur much less frequently.

Also, among the possible negative manifestations in the process of using “ACC” for children (syrup), the instructions for use inform about the risk of lowering blood pressure, the development of tachycardia (rapid heartbeat), bronchospasms, and the appearance of urticaria.

If any negative reactions occur during therapy using ACC, you must stop taking the medication and contact your pediatrician without fail.

Exceeding the permissible dosage

An overdose of the drug "ACC" can occur in several cases. It is possible for a child to take a dose calculated for an adult patient, use the medication in an excessive amount without special instructions from a doctor, or accumulate it (“ACC”) in the body, which is possible with a long course of treatment without proper monitoring of the condition of the liver, kidneys, and blood counts. In any case, the possible reactions of patients to “ACC” (for children - syrup), the instructions for use describe such manifestations as a drop in blood pressure, nausea, vomiting, and a feeling of dry mouth. There is also a possibility of allergic dermatitis, accompanied by a rash and itchy skin, and bronchospasm may develop.

In especially severe cases, doctors talk about the possibility of angioedema and shock.

Interaction with other drugs

All information about possible drug interactions is contained in the instructions for use for “ACC” (syrup). For children over one year of age, it can be taken only in the most extreme cases and under the supervision of a doctor. Although, when used in parallel with ACC, there is a danger for patients of any age.

There is information about the incompatibility of the main active ingredient “ACC” with semisynthetic penicillins, cephalosporins, and aminoglycosides. On the contrary, there is no information about the incompatibility of acetylcysteine ​​with such antibacterial drugs as Amoxicillin, Erythromycin and Cefuroxime.

What should you pay attention to?

As mentioned earlier, for the treatment of patients from 2 to 5 years of age, doctors usually prefer the drug “ACC 100” (syrup). Instructions for use for children, reviews of children's doctors warn parents about the inadmissibility of taking “ACC” and any antitussive medications together. With this parallel use, “ACC” dilutes sputum, and antitussives suppress the cough reflex, sputum is not coughed up. This is fraught with stagnation of sputum, which seriously threatens the health and sometimes the life of the child.

Pediatricians also do not prescribe ACC together with antibacterial agents, since they may be incompatible. Only a few types of antibiotics of the tetracycline, penicillin and cephalosporin series can be used together with ACC with intervals of at least 2 hours between doses.

It is permissible to dilute ACC granules and powders yourself only in glass containers. It is recommended to avoid contact with rubber or metal.

When treating with ACC, it is necessary to increase the volume of fluid consumed. This will significantly enhance the mucolytic effect of the drug. Children should take ACC no later than 4 hours before bedtime.

Consumer opinion about the medicine

The patients' parents are satisfied with the drug "ACC" (syrup). Instructions for use for children (consumer reviews confirm this fact) give clear instructions on the method of use of the drug and dosage. Cough in children usually becomes productive very quickly and goes away within 3-4 days. That is, the product is effective in almost 100% of cases of use.

The syrup has a pleasant orange flavor, so even the most capricious patients do not have to be forced to take the medicine for a long time. In addition, the cost of “ACC” is available to a wide range of consumers with very different levels of financial capabilities. The product is very convenient to store; it will not be difficult to take it with you on the road.

ACC, of ​​course, has certain contraindications and side effects, but using it only as prescribed by the attending physician and following all recommendations will eliminate most of the unpleasant consequences and manifestations.

The child will breathe deeply and calmly, and parents will not worry about his well-being.

ACC is an effective mucolytic agent that helps with cough. It is a safe and easy-to-use drug. The cough medicine Ass can also be given to children over a certain age, in the form of syrup.

The main active ingredient of the drug is acetylcysteine ​​- an amino acid, which, by its action, thins phlegm, making it less viscous and, removing it from the lungs, makes dry cough softer.

Cough tablets can be purchased as injections, syrup (most often prescribed to children), dissolvable granules for cough syrup or solution, and effervescent tablets. Each form of the drug contains flavoring additives and aromas. They are produced in blackberry, orange, lemon, etc. flavors. Powder for preparing the solution and ACC tablets are most in demand because they are easy to use and have a quick therapeutic effect. ACC price for a medicine directly depends on the form of release and dose of the drug.

Pharmacological action

For cough, ACC long or any other form with different doses of the active ingredient and auxiliary components affects the body as follows:

• The medicine has an antioxidant effect. The negative impact on mucosal cells is reduced due to the active reduction of free radicals.
• . Reduces viscosity and thins mucus formations, which facilitates their exit from the body.
• Anti-inflammatory effect. Fights infectious cells. Able to cope with even the most difficult ones - purulent and viscous.

To treat a cough, the most important thing is to remove mucus from the lungs as quickly as possible. The medicinal composition of ACC copes with this perfectly.

ACC: indications for use

Indicated for all types. Effervescent tablets or powder for preparing a solution are taken when mucus accumulates in the lung cavity. Diseases in which this symptom is observed are the following:

• ARVI, acute respiratory infections and simple colds (even when it all started with a runny nose, and there are no complications, there is a high probability that mucus will descend into the lungs and a cough will begin);
• bronchitis;
• tracheitis;
• chronic obstructive pulmonary diseases (if prescribed by a doctor);
• pneumonia;
• cystic fibrosis (if prescribed by a doctor);
• lung abscess;
• bronchial asthma;

Remember that no matter how well you understand medications, it is always better to consult a doctor.

How to take

ACC is taken for both dry and wet coughs.

The instructions for using ACC are different for some forms, so if you have already taken, for example, tablets, you should not take the syrup according to the same regimen. Be sure to read the instructions first.

Must be taken orally after meals. Of course, with the exception of ampoules for injections. The best instructions would be to have the drug prescribed by a doctor and have a clear dosage regimen. But, if for some reason you decide to take ACC yourself, follow the instructions for use below.

Granules and tablets

Dissolve in 1 tbsp. hot water. You should also drink the solution freshly prepared and hot.

• Adults and children over 14 years old – 1 pack/1 tablet. – 1 time per day.
• You can take the drug for 5-7 days. If there is no improvement, you should consult a doctor.

Remember that copious fluid intake (preferably pure water) significantly enhances the effect of any mucolytic drug.

Use of granules or effervescent tablets during pregnancy or lactation.

The use of these dosage forms of ACC during pregnancy and breastfeeding is prohibited.

Syrup

• Adults and children over 14 years old – 10 ml 2-3 times a day.
• Children from 6 to 14 years old - 5 ml of syrup 3-4 times a day or 10 ml 2-3 times a day.
• Children from 2 to 6 years old – 5 ml of syrup 2-3 times a day.

Solution for intravenous and intramuscular administration

The solution must be administered intravenously or intramuscularly.

IV administration:

If it is impossible to take ACC drugs orally, intravenous injections are administered only in the hospital, in intensive care units.

IM injection:

For intramuscular injections, the needle should be inserted deep into the muscle.

• Adults and children over 14 years of age must administer the drug intravenously or intramuscularly, 3 ml 1-2 times a day.
• For children aged 6 to 14 years, the drug is administered intravenously or intramuscularly, 1.5 ml 1-2 times a day.
• For children under 6 years of age, administration of the drug intravenously or intramuscularly is not recommended. In cases where parenteral therapy is necessary, it is worth adhering to the recommended daily dose of 10 mg per 1 kg of body weight.

Children under 1 year of age are allowed to administer the drug intravenously or intramuscularly only in a hospital setting and only when there is no threat to the child’s health.

Use during pregnancy and breastfeeding

It is not recommended to take ACC syrup during pregnancy or breastfeeding. However, if the potential benefit to the mother outweighs the possible risks to the fetus, the drug can be taken under the strict guidance of a doctor.

It is not recommended to administer ACC solution intravenously or intramuscularly or breastfeeding.

Contraindications

Before taking any form of the ACC drug, special attention should be paid to the existing contraindications:

• individual intolerance to the components of the product;
• bleeding in the lung cavity;
• stomach ulcers;
• pregnancy;
• lactation period.

Use the product with caution if you are intolerant to the component of the drug - histamine, as well as with varicose diseases of the venous system and diseases associated with the kidneys or liver.

Side effects

Despite the fact that when taking ACC drugs according to the instructions, there are almost no side effects, you should still be aware of the possibility of the following manifestations:

• allergic rashes;
• dizziness;
• headaches;
• nausea, vomiting;
• shortness of breath.

This is possible in case of an overdose of the prescribed dosage at your age and the characteristics of the medicinal doses, if you are unaware of intolerance to any components of the drug or any diseases.

Analogs

Analogues of various forms of the drug ACC containing the same or similar main active ingredient and having a similar effect on the body:

• Atsestad;
• Asibrox;
• Abrol;
• Acetal;

Some of them are more affordable.

Price category of ACC drugs

Prices for ACC in the form of granules vary in different cities and pharmacies from 100 to 200 rubles. The cost of syrup can range from 200 to 250 rubles. The price of effervescent tablets starts from 300 rubles and reaches 500. It all depends on the region in which you live, on the type of pharmacy - whether it is private or public.

Special instructions

To ensure that taking various forms of ACC medication brings you only benefit, follow these recommendations:

• Take the drug with caution if you have bronchial asthma or obstructive bronchitis. It is better to consult a doctor before use, and take it under his strict supervision.
• The medicine contains sucrose, so people with diabetes should take the drug with caution or under the supervision of a doctor.
• If after using the drug you notice any unusual symptoms in yourself, you should immediately consult a doctor.
• When preparing various forms of the drug, it is necessary to avoid substances that oxidize easily. And mix them with water only in glass containers.
• ACC preparations are recommended to be used before 18:00 pm.

By following the basic rules, treatment with the drug will bring a quick therapeutic effect and speed up the recovery period.

Acetylcysteine ​​is a mucolytic, expectorant, derivative of the amino acid cysteine. Due to the presence of a free sulfhydryl group, acetylcysteine ​​breaks the bisulfide bonds of acidic mucopolysaccharides of sputum, which leads to depolymerization of mucoproteins and increases the viscosity of bronchial secretions. The drug facilitates sputum discharge by increasing mucociliary clearance. Acetylcysteine ​​also has antioxidant and pneumoprotective properties, which is due to the ability of sulfhydryl groups to bind free radicals. In addition, acetylcysteine ​​helps increase the synthesis of glutathione, which is an important detoxification factor. This feature of acetylcysteine ​​makes it possible to use it as an antidote for acute poisoning with paracetamol and other substances (aldehydes, phenols, etc.)
After oral administration, acetylcysteine ​​is quickly and almost completely absorbed from the digestive tract. In the liver it is metabolized to cysteine ​​(a pharmacologically active metabolite) and diacetylcystine, cystine and then to mixed disulfides. The bioavailability of acetylcysteine ​​after oral administration is about 10%. The maximum concentration after oral administration is achieved after 1-3 hours. The main metabolite of the drug, cystine, is determined in the blood plasma at a maximum concentration of 2 µmol/l. About 50% of the drug binds to blood plasma proteins. In the body, acetylcysteine ​​and its metabolites are determined in various forms: partly as a free substance, partly in connection with blood plasma proteins, partly as incorporated amino acids. It is excreted almost completely in the form of inactive metabolites (inorganic sulfates, diacetylcystine) in the urine. Only a small amount of acetylcysteine ​​is excreted unchanged in the feces. The half-life from blood plasma is approximately 1 hour and depends on the rate of biotransformation in the liver. In case of liver failure, it can be extended up to 8 hours. Acetylcysteine ​​can penetrate the placental barrier and accumulate in the amniotic fluid.

Indications for use of the drug ACC

Diseases of the respiratory tract accompanied by the formation of viscous secretions, including acute and chronic bronchitis, bronchiectasis, chronic obstructive bronchitis, asthma, bronchiolitis, cystic fibrosis, tracheitis, laryngitis, as well as sinusitis and exudative otitis media.

Use of the drug ACC

Adults and children over 14 years of age are prescribed at a dose of 400-600 mg/day, children aged 6-14 years - at a dose of 300-400 mg/day in 2 doses, from 2 to 5 years - 200-300 mg/day . Infants from the 10th day of life and children under 2 years of age are prescribed 50 mg 2-3 times a day.
For cystic fibrosis patients weighing 30 kg, a dose of up to 800 mg/day is acceptable. Children over 6 years of age are usually prescribed 200 mg 3 times a day, 2-5 years old - 100 mg 4 times a day, infants (starting from the 10th day of life) and children under 2 years of age are prescribed 50 mg 2-3 times a day.
Take after meals. The contents of the sachet or tablet are dissolved in 1/2 glass of water, juice or iced tea. For acute uncomplicated diseases, the duration of use of the drug is usually 5-7 days. Treatment for chronic diseases is carried out over a long period of time or in courses of several months (up to 6 months).

Contraindications to the use of the drug ACC

Hypersensitivity to acetylcysteine ​​or other components of the drug, peptic ulcer of the upper gastrointestinal tract, hemoptysis, pulmonary hemorrhage.
ACC Children's is contraindicated in case of hepatitis, renal failure (to avoid an increase in nitrogen-containing substances in the body).

Side effects of the drug ACC

Heartburn, nausea, vomiting, diarrhea, headache, stomatitis, tinnitus, allergic reactions, arterial hypotension, bronchospasm (in persons with bronchial hyperreactivity), skin rash and itching, and tachycardia may occur extremely rarely.
Methyl parahydroxybenzoate and propyl parahydroxybenzoate may cause isolated hypersensitivity reactions. At the first signs of hypersensitivity reactions, stop taking the drug.

Special instructions for the use of the drug ACC

Acetylcysteine ​​should be used with caution in patients with gastric or duodenal ulcers.
The drug should be used with caution in patients with asthma. This is explained by the fact that during the preparation of the solution, reflex bronchospasm may occur, since the powder may enter the inhaled air, resulting in irritation of the nasal mucosa.
During treatment with acetylcysteine, it is recommended to drink a sufficient amount of fluid.
Patients with rare hereditary fructose intolerance should not take the drug.
Help for patients with diabetes and patients with congenital hypersensitivity to fructose. 10 ml (2 scoops) of ready-to-use solution contains 3.7 g of sorbitol (source: 0.93 g of fructose), which corresponds to 0.31 carbohydrate units.
Sorbitol may have a mild laxative effect.
Additional fluid intake enhances the mucolytic effect of the drug.
Children
For children under 1 year of age, acetylcysteine ​​is prescribed only for health reasons; Treatment is carried out under the strict supervision of a doctor.
Acetylcysteine ​​should only be used in children under 2 years of age under medical supervision.
The drug is prescribed to newborns only for health reasons and under strict medical supervision, not exceeding a dose of 10 mg/kg body weight.
ACC 200 should not be used to treat children under 2 years of age, and ACC LONG should not be used in children under 14 years of age.
Despite the fact that there is no information about the embryotoxic effect of acetylcysteine, during pregnancy the drug is prescribed only according to strict indications and under the supervision of a physician.
The ability to influence reaction speed when driving vehicles or working with other mechanisms. There is no evidence of a negative effect on the ability to drive vehicles or operate complex machinery.

Drug interactions ACC

Tetracycline antibiotics (with the exception of doxycycline) are not recommended for use simultaneously with ACC Children.
Cases of inactivation of antibiotics of other groups by acetylcysteine ​​were noted exclusively during experiments in vitro, with direct mixing of the latter. But for the safety of the patient, the interval between taking antibiotics and acetylcysteine ​​should be at least 2 hours.
When using the drug simultaneously with antitussives, due to a decrease in the cough reflex, dangerous stagnation of mucus is possible.
Acetylcysteine ​​may potentiate the vasodilating effect of nitroglycerin. In vitro There is incompatibility of acetylcysteine ​​with semisynthetic penicillins, cephalosporins, and aminoglycosides. There is no data on the incompatibility of the drug with antibiotics such as amoxicillin, erythromycin and cefuroxime.

Overdose of the drug ACC, symptoms and treatment

Severe and life-threatening side effects have not been described in such cases. Very rarely, nausea, vomiting and diarrhea are possible. There is a risk of hypersecretion in infants.
Treatment symptomatic.

Storage conditions for the drug ACC

At a temperature not exceeding 30 °C. Store the prepared solution at a temperature of 2-8 °C for no more than 12 days.

List of pharmacies where you can buy Acc:

• Saint Petersburg

Name:

ACC

Pharmacological
action:

Acetylcysteine ​​(ACC) - mucolytic, expectorant, which is used to thin sputum in diseases of the respiratory system accompanied by the formation of thick mucus. Acetylcysteine ​​is a derivative of the amino acid cysteine.
The mucolytic effect of the drug is of a chemical nature.
Due to the free sulfhydryl group, acetylcysteine ​​breaks the disulfide bonds of acidic mucopolysaccharides, which leads to depolymerization of sputum mucoproteins and a decrease in the viscosity of mucus and promotes expectoration and discharge of bronchial secretions.
The drug remains active in the presence of purulent sputum.
Acetylcysteine also has antioxidant pneumoprotective properties, which is due to its binding by sulfhydryl groups of chemical radicals and, thus, neutralizing them.

In addition, the drug helps to increase the synthesis of glutathione - an important factor in intracellular protection not only from oxidative toxins of exogenous and endogenous origin, but also from some cytotoxic substances.
This feature of acetylcysteine ​​makes it possible to effectively use the latter in case of an overdose of paracetamol.
After oral administration acetylcysteine quickly and completely absorbed and is metabolized in the liver to form cysteine, a pharmacologically active metabolite, as well as diacetylcysteine, cystine, and then mixed disulfides.
Bioavailability is very low - about 10%.
Cmax in blood plasma is achieved 1–3 hours after administration. Binding to blood plasma proteins - 50%.
Acetylcysteine ​​is excreted by the kidneys in the form of inactive metabolites (inorganic sulfates, diacetylcysteine).
T½ is determined mainly by rapid biotransformation in the liver and is about 1 hour. In case of decreased liver function, T½ increases to 8 hours.

Indications for
application:

Acetylcysteine ​​is prescribed in all cases of diseases with accumulation of thick viscous sputum in the bronchial tree and upper respiratory tract, namely:
- acute and chronic bronchitis, including obstructive;
- bronchiolitis;
- tracheitis;
- bronchial asthma;
- bronchiectasis;
- cystic fibrosis;
- laryngitis;
- sinusitis;
- exudative otitis media.

Directions for use:

Daily dose for the treatment of cystic fibrosis For patients weighing more than 30 kg, up to 800 mg is used.
Children from the 10th day of life to 2 years of age are given 50 mg 2-3 r/s.
At the age of 2-5 years – 400 mg per day, divided into 4 doses. From 6 years – 600 mg/s (divided into 3 doses).
Treatment is continued for a long time, in courses of several months (3-6).
In all other cases, the daily dose for children over 14 years of age and adults is 400-600 mg. From 6 to 14 years – 300-400 mg (divided into 2 doses), 2-5 years – 200-300 mg (divided into 2 doses).
Children from the 10th day of life to 2 years of age are treated with 50 mg 2-3 r/s.

For acute diseases without complications the drug is prescribed for 5-7 days.
In case of complications or in case of chronic course, a course of treatment is possible (up to 6 months).
ACC is taken after meals.
The tablet or contents of the sachet must be dissolved in half a glass of liquid (iced tea, water, juice).

Side effects:

To describe the frequency of side effects, the following classification is used: very often (≥1/10), often (≥1/100,<1/10), нечасто (≥1/1000, <1/100), редко (≥1/10 000, <1/1000), очень редко (<1/10 000).
From the cardiovascular system: infrequently - tachycardia, arterial hypotension.
From the nervous system: uncommon - headache.
From the skin: uncommon - allergic reactions (itching, urticaria, exanthema, eczema, rash, angioedema).
From the side of the hearing organ: uncommon - ringing in the ears.
From the respiratory system: rarely - shortness of breath, bronchospasm (mainly in patients with hyperreactivity of the bronchial system, which is associated with asthma), rhinorrhea.

From the digestive tract: uncommon - heartburn, dyspepsia, stomatitis, abdominal pain, nausea, vomiting, diarrhea, bad breath.
General disorders: uncommon - fever.
Isolated severe skin reactions (Stevens-Johnson and Lyell syndromes) have been reported.
When using acetylcysteine, bleeding was very rarely reported, which was most often associated with the development of hypersensitivity reactions.
Cases of decreased platelet aggregation have been reported, but there is no clinical confirmation of this.
Very rarely Angioedema, facial swelling, cases of anemia, hemorrhage, anaphylactic reactions or even shock have been reported.

Contraindications:

Hypersensitivity to acetylcysteine ​​and excipients;
- peptic ulcer;
- hereditary fructose intolerance;
- pulmonary hemorrhage or hemoptysis;
- in pediatric practice - for hepatitis and renal failure (threat of accumulation of nitrogen-containing products).

Use ACC with caution with peptic ulcer of the stomach or duodenum.
When preparing the solution, a patient with bronchial asthma may inhale air containing particles of the drug, which causes irritation of the mucous membranes of the upper respiratory tract and can provoke reflex bronchospasm.
For a better mucolytic effect, you should take plenty of fluids when treating with acetylcysteine.
10 ml of ready-made oral solution contains 0.31 carbohydrate units, which should be taken into account by patients with diabetes mellitus.
Sorbitol has a slight laxative effect on stool.

Newborns and children under 1 year of age acetylcysteine ​​is used exclusively for health reasons under strict medical supervision. The recommended dosage (10 mg/kg body weight) cannot be changed.
ACC 200 is not used for children under 2 years of age.
ACC Long is not recommended for children under 14 years of age.
Reaction speed when driving and operating equipment does not change when taking acetylcysteine.

Interaction with
other medicinal
by other means:

Tetracycline and its derivatives (except doxycycline) should not be used together with ACC in pediatrics.
During experimental in vitro studies, no cases of inactivation of other types of antibacterial drugs were identified.
Nevertheless, It is recommended to maintain a gap between taking ACC and antibiotics at 2 o'clock (at least).
In vitro, the incompatibility of acetylcysteine ​​with semisynthetic penicillins, aminoglycoside and cephalosporin antibiotics has been proven. Such studies have not been conducted with erythromycin, amoxicillin and cefuroxime.
The simultaneous use of antitussives can lead to stagnation of respiratory tract secretions.
Use with nitroglycerin may enhance the vasodilator effect of the latter.

Pregnancy:

Acetylcysteine ​​has no embryotoxic effect, however, during pregnancy, as well as during breastfeeding, it is prescribed only if indicated under the supervision of a physician.

Overdose:

There are no data on cases of overdose of acetylcysteine ​​dosage forms intended for oral administration.
Acetylcysteine ​​when taken at a dose of 500 mg/kg/day does not cause signs and symptoms of overdose.
Symptoms: Overdose may result in gastrointestinal symptoms such as nausea, vomiting and diarrhea.
Treatment: there is no specific antidote for acetylcysteine ​​poisoning, therapy is symptomatic.

Release form:

ACC 100, 200 - effervescent tablets 20 pcs.
ACC hot drink – hot drink powder for internal use- 200 mg (20 sachets) and 600 mg (6 sachets).
ACC-long – effervescent tablets (600 mg), 10 pcs. in the tube.

ACC powder for the preparation of solution for oral administration – 100, 200 mg, 2 pcs. in packaging.
ACC for children - powder for preparing a solution for internal use, 30 g in a 75 ml bottle (20 mg/ml) and 60 g in a 150 ml bottle (20 mg/ml).

Storage conditions:

In places inaccessible to children.
Temperature no more than 30°C.
The prepared solution can be stored for no more than 12 days in the refrigerator (at a temperature of 2-8°C).

1 sachet (100 mg) ACC granules for oral solution (orange) contains:

- excipients: ascorbic acid, sucrose, saccharin, orange flavor.

1 effervescent tablet (100 mg) ACC contains:
- active ingredient: acetylcysteine ​​- 100 mg;
- excipients: citric acid anhydride - 679.85 mg, sodium bicarbonate - 291 mg, mannitol - 65 mg, ascorbic acid - 12.5 mg, lactose anhydride - 75 mg, sodium citrate - 0.65 mg, saccharin - 6 mg, blackberry flavoring "B" - 20 mg.