Suppositories are one of the most popular treatment options for candidiasis. Among other drugs, the gynecologist may prescribe Polygynax for thrush to the patient. How do these suppositories work?

Mechanism of action

Polygynax is a highly effective remedy in the fight against yeast-like fungi of the genus Candida because it combines a number of effective components at once.

Its basis is the antibiotic substances polymyxin and neomycin, which prevent the reproduction of pathogenic microorganisms and their normal functioning.

As a result, the mucous membranes of the vagina return to their normal state. Additional elements that make up Polygynax are:

Despite a wide range of effects on fungi, Polygynax does not adversely affect the natural vaginal microflora. It is practically not absorbed into the mucous membranes and is evenly distributed over the affected areas after the capsule is dissolved.

Who uses this drug and how?

Polygynax from thrush is used as one of the options for mandatory course therapy. In most cases, even severe fungal manifestations disappear already on the 3rd day after the start of treatment.

Note!

If you have begun to inject capsules into the body, you cannot stop doing this without special prescriptions from a doctor, otherwise the effect of Polygynax will not only come to naught, but will also add health problems. If only one day is missed, therapy should be resumed on the next day, and without compensation for the “lost” procedure.

The lack of systematic administration of Polygynax can lead to the development of chronic candidiasis with regular relapses of the disease. Fungi will gradually develop "immunity" to the components that form the drug, and therefore it will be much more difficult to get rid of them.

At the same time, despite the fact that Polygynax is considered an antibiotic, there are no exact prescriptions regarding the daily time of its introduction into the body.

In addition to vaginal candidiasis, doctors also prescribe these suppositories to those patients who are diagnosed with bacterial vaginitis, cervical erosion, fungal or bacterial cervicitis, and nonspecific varieties of vaginitis.

Polygynax is available in the form of an emulsion and in the form of vaginal capsules that are more popular with patients. The drug is not intended for men. For children there is a special product - "Polygynax Virgo".

Minimum contraindications

Polygynax for thrush is forbidden to use only a very small group of women. These are the patients:

1. Having allergies and individual intolerance to the elements that make up the suppositories.
2. Those in the first trimester of pregnancy. In the 2nd and 3rd trimester, the use of suppositories should be carried out with caution.
3. Breastfeeding newborn babies.
4. Suffering from renal insufficiency. Excessive use of the remedy can only aggravate the existing ailment.

Cases of incompatibility of Polygynax with other drugs in medical practice have not been identified. The tool can only weaken the effect of other products. The drug is approved for use during menstruation. But from alcohol and sexual intercourse with a partner during the treatment period, you will have to refrain.

Of the various adverse reactions, Polygynax can only provoke an allergy, which manifests itself in the form of rashes, itching, swelling of the mucous membranes and drug-induced urticaria.

Note!

Many patients who use these suppositories for the treatment of thrush note that in the morning they have an abundant release of a translucent liquid. Such a manifestation is a variant of the norm, and not an unfavorable side symptom. Interrupt treatment with candles should not be.

Application rules

According to the instructions, which do not take into account the individual characteristics of the body or the specific course of the disease, Polygynax for thrush should be used 1 time per day, preferably before going to bed.

Suppositories must be inserted as deep as possible into the vaginal passage. The duration of treatment is 12 days. As part of the prevention of candles, you should use only 6 days. Additional recommendations for the use of suppositories are established by the attending physician.

Price category

The democratic cost of the drug is a significant plus for many women suffering from vaginal candidiasis. A package with 6 capsules can be purchased for an average of 350 rubles, and with 12 capsules - for 550 rubles.

And what is the cost of this drug in your pharmacies ???

The choice of a drug that would quickly help get rid of thrush can be difficult. The number of drugs in pharmacies is very large. Therefore, in order not to miscalculate and conduct an effective therapy aimed at suppressing the activity of a pathogenic fungus, you need to visit a doctor. Only after collecting anamnesis, examination and testing, the gynecologist will be able to choose the medicine with confidence, based on the individual characteristics of the patient. In many cases, if there are no serious contraindications or other factors, suppositories are prescribed as part of therapy, the beneficial effects of which have long been noted by the fair sex, doctors. This form of topical preparation successfully eliminates the symptoms, does not bring discomfort and cures the disease. Polygynax is one of the most popular means of this kind. What is remarkable about this drug?

Features of the drug

Polygynax is an effective and fast-acting drug that belongs to the price category among the available drugs.

Polygynax packaging

Its cost in pharmacies is about 400 rubles per pack. It is noted that this remedy successfully treats not only various forms of thrush, but is also able to cope with other gynecological diseases that occur on their own or against the background of chronic candidiasis. At the same time, candles of this brand are among the antibiotics, due to which the instructions should be carefully studied before the first use, and it is also important to remember all the advice of the attending physician.

Polygynax is used for thrush in the variant of mandatory course treatment. The pronounced symptoms of fungal pathology usually disappear completely already on the third day after the first injection of the capsule into the body. However, it is impossible to interrupt the started therapy, if there are no serious prescriptions for such an action. Despite the fact that the drug falls into the category of antibiotics, there are no separate requirements that the drug should be administered strictly at the same time. Also, in case of skipping a day, treatment should continue without compensating for the “loss of a day”, but it is recommended, under such a set of circumstances, to consult a gynecologist for a possible correction of the therapy plan.

The main active substances in this drug are:

Excipients:

• glycerol;
• water;
• gelatin;
• soybean oil (hydrogenated);
• typhus 63.

Candles have antibacterial and antifungal effects on the body. Due to this, Polygynax is used not only to correct the condition with thrush, but also in the framework of such gynecological diseases as cervical erosion, bacterial vaginitis, cervicitis (bacterial and fungal), with non-specific forms of vaginitis. The components of the drug quickly block the growth of the number of pathogenic organisms, destroy the already existing negative microflora. In addition, suppositories successfully cope with itching, unpleasant vaginal discharge, swelling and irritation of the mucous membranes.

Polygynax has almost no side effects

Unlike many other "strong" drugs, Polygynax has practically no side effects, contraindications, and there have been no cases of overdose with concomitant symptoms. Thus, the remedy requires a competent reception, so that the instructions are followed, only for the reason that, otherwise, the therapy may not bring the proper result. It is noted that when the course is interrupted or the non-systematic administration of medicinal capsules, thrush passes into the chronic stage with frequent relapses, and the yeast-like fungus gradually develops "immunity" to the main components of the drug. Due to this, further treatment with nystatin-based agents may be completely ineffective.

The minimum contraindications include:

1. individual intolerance and allergy to the composition of Polygynax;
2. early pregnancy (first trimester), candles should be used with caution in the 2nd and 3rd trimesters;
3. kidney failure; excessive use of the drug can worsen the well-being of such patients;
4. breastfeeding period.

No alcohol during treatment.

You can resort to the help of this medicine at the time of menstruation. But from the use of alcohol throughout the course of treatment will have to refrain. Sexual intercourse with a regular partner, who must also undergo therapy against candidiasis, is not welcome and is permissible only with the consent of the attending physician.

Possible side effects:

• allergic reaction (itching, skin rashes, swelling of mucous membranes, drug-induced urticaria).

Many women during therapy note the presence of abundant translucent vaginal discharge in the morning. This is not a pathological reaction or side effect. Interrupt therapy should not be.

Polygynax is produced in two forms: vaginal capsules and emulsion. Packings of capsules can be of two types: for 6 pieces and for 12. The color of the candle is milky, small in size, quite elastic, oval in shape.

Polygynax Virgo

The use of the drug Polygynax for men is prohibited. For children, a separate form of the remedy called "Polygynax Virgo" is produced.

These suppositories are also prescribed as a prophylaxis, before abortions and other surgical interventions.

How to use the drug for the treatment of vaginal candidiasis

In order to feel the necessary dynamics in the course of treatment, it is important to use the capsules exactly in the amount and with the regularity prescribed by the doctor. The introduction of the agent into the body is carried out only after all the necessary hygiene procedures.

The main instruction for the tool is as follows (without taking into account individual indications):

• with targeted therapy against candidiasis and other related diseases of the gynecological sphere, capsules are used once a day at bedtime; to enter the suppository in solid form should be as deep as possible into the vagina; the duration of the course is 12 days;
• as part of preventive measures, the duration of exposure is 6 days; the remedy is also administered once a day, in the evening.

Depending on the course of thrush, the presence of additional pathologies, the doctor may adjust recommendations for the use of Polygynax.

Effective treatment of candidiasis involves a combined approach, part of which are vaginal suppositories. However, you should not choose a drug based on the advice of friends. Only a competent doctor, based on the results of research and taking into account the characteristics of the body, is able to draw up the correct plan for correcting the condition.

Polygynax is a fairly common remedy that is used for thrush. These are vaginal suppositories, which, according to the instructions for use, in just a few days will help a woman eliminate the unpleasant consequences of bacterial vaginosis, that is, thrush. Moreover, the active components of Polygynax not only suppress pathogens in the vagina, but also prevent the infection from reappearing in a woman.

When is Polygynax prescribed?

Polygynax is prescribed for infectious and inflammatory processes of the vagina, for pathologies of the pelvic organs, as well as for such pathological conditions as:

• vaginitis;
• The defeat of the microflora of the vagina by fungal microorganisms;
• For the prevention of inflammatory processes of the vagina;
• Before performing operations on the pelvic organs;
• During diathermocoagulation of the cervix;
• After an abortion;
• Before childbirth, as a preventive measure to avoid damage to the birth canal by infections and inflammatory processes.

In what dosage are Polygynax suppositories used?

The instructions for use indicate that the course of treatment (thrush) is 12 days. Every day, at night, a woman should insert one capsule of Polygynax into the vagina. For preventive measures, the course of therapy is 6 days.

In the case of a missed capsule at night, it is necessary to continue treatment the next day as before (2 capsules are not needed).

Can there be contraindications to the use of Polygynax?

Are there any contraindications to the use of Polygynax? According to the instructions for the use of Polygynax suppositories, there are no contraindications to this drug.

Side effects

It is possible that patients may experience individual intolerance to the active components of Polygynax. In this case, a number of side effects may occur in the form of an allergic reaction of the vagina, an unpleasant burning sensation, itching in the perineum, and redness.

How often to use Polygynax suppositories?

If you are prone to having thrush at least once a year, then in this case, preventive measures with the use of Polygynax should be carried out quite regularly - at least 2 times a year (therapy for 6 days, 1 vaginal suppository).

It is forbidden to accept!

• Candles Polygynax are not accepted in the 1st trimester of pregnancy;
• Not recommended for use during breastfeeding.
• During treatment, complete sexual rest is necessary.

It is advisable, before using Poligynax suppositories, to consult a gynecologist for an appointment and advice.

What is in the Poligynax capsules?

Polygynax vaginal suppositories contain neomycin sulfate, polymyxin sulfate, dimethicone, nystatitn, water, hydrogenated oil.

Feedback on the use of candles Polygynax

• “I have been using Polygynax candles for 4 years now - they have always helped me out! For some reason, only this drug helped me remove thrush. All other known suppositories from thrush provoked unpleasant itching in the vagina, burning, rash and redness. It is very important to put candles for 12 days, as indicated in the instructions - otherwise everything is down the drain. Thrush can be cured, but only if you follow the instructions for the drug. (Olga, 30 years old)
• “I recommend these candles to all my friends and acquaintances. I suffered from several years. After the appearance of a permanent sexual partner, she infected him with this disease. We started healing together. My gynecologist recommended that I put 1 Polygynax suppository at night for 12 days in a row and at the same time not have sex all this time. For the first time in this time, I felt relief - the unpleasant white discharge disappeared, the smell from the vagina disappeared, and my intimate life only improved. Since then, I always buy these candles for my first-aid kit, every couple should have them. (Tamara, 21 years old)
• “Don't repeat my mistakes. For 4 days I put myself one Polygynax candle at night. On the 5th day there were no traces of this nasty thrush, and I decided to stop the treatment. Girls, don't do what I do. 3 days after I finished putting the candles, the symptoms of thrush returned to me again. Only then I read the instructions for the drug and saw that they need to be put exactly 12 days. I started the treatment again and it turned out to be effective. The thrush has not come to me for 2 years.” (Svetlana, 40 years old).
• “It took me 2 courses of Polygynax suppositories to get rid of this unpleasant and painful diagnosis of bacterial vaginosis. The gynecologist prescribed me 2 courses of treatment, in each half of the year, put 1 Polygynax suppository in the vagina at night. The milkmaid passed without a trace. Although before that I had tried a large number of medicines, from sprays to serious antibiotics - nothing helped. (Eva, 35 years old).
• “I used candles according to the instructions - 12 days in one month and 6 days in another (but, this is already for safety net and prevention). The thrush doesn't come back and doesn't bother me. Recommend!". (Julia, 19 years old).
• “I put candles for 5 days, they didn’t help, although it may have been necessary to put more days. As a result, I switched to in combination with flucostat. (Dina, 32 years old).
• “It's amazing, but I treated thrush with Polygynax suppositories, and killed two birds with one stone - I also had cervical erosion without a trace. Very good remedy, these vaginal suppositories. I used 2 packages, 12 candles in total. (Tamara, 26 years old).
• “I used Polygynax suppositories for six months - 2 times for 12 days and the thrush passed without a trace, as if it had never happened, although before I could not cure it with anything. This tool is not cheap, but it is effective! (Miroslava, 18 years old).
• “I treated thrush with Polygynax a year ago, but now it has reappeared. Now I bought another pack of candles and I hope that it will help as well as the first time. (Ira, 25 years old).

1 capsule includes 100,000 IU nystatin , 35000 IU neomycin sulfate , 35000 IU polymyxin B sulfate .

Optional: 30mg hydrogenated soybean oil, 125mg tefose 63, up to 2500mg dimethicone 1000.

Shell: 191.5 mg glycerol, 381.2 mg gelatin, 86.9 mg dimethicone 1000.

Release form

The drug Polygynax is produced in the form of vaginal capsules (candles), 6 or 12 pieces in a blister, placed in a cardboard box.

pharmachologic effect

Local antibacterial and antifungal .

Pharmacodynamics and pharmacokinetics

Polygynax is a local combination remedy with antifungal and antibacterial efficiency and applicable in gynecology . Capsules of the drug are characterized bactericidal activity against various .

The central action of the active ingredients of this medicinal product from the group – Polymyxin B and - aimed at suppressing the activity of many bacterial microorganisms both Gram-positive and Gram-negative. Show no sensitivity to the effects of these drugs anaerobic bacteria and streptococci .

Third antibacterial active ingredient of capsules - nystatin - differs in fungicidal action towards fungal strains of the genus Candida , in connection with which there is a high efficiency of the drug Polygynax in . The drug has a beneficial effect on the trophic processes occurring in the vaginal mucosa, and has a fairly wide spectrum of action, ranging from thrush and ending with others fungal infections of the vagina .

With intravaginal use, all three active ingredients of the capsules are evenly distributed over the entire mucous surface of the vagina, where their local fungicidal and bactericidal effects. The absorption of the active ingredients of the drug from the vaginal mucosa into the systemic circulation is practically zero.

Indications for use

As a therapeutic agent for therapy infectious and inflammatory disease conditions caused by sensitive to the active ingredients of the drug microorganisms , Polygynax is prescribed for: , vulvovaginitis , fungal vaginitis , cervicovaginitis , mixed vaginitis .

With the aim of prevention possible infectious complications capsules of the drug are indicated for use: before starting labor activity , on the eve of gynecological surgical interventions, before carrying out intrauterine diagnostic procedures , before and after execution diathermocoagulation of the uterine neck .

Contraindications

The use of Polygynax is absolutely contraindicated in the case of a personal hypersensitivity to the ingredients of capsules, as well as women in the first trimester pregnancy and lactating breastfeeding mothers.

Side effects

When conducting local treatment using Polygynax capsules, the following were occasionally observed: manifestations , irritation in the vagina, and burning vaginal mucous membranes. In some cases, the formation allergic contact . With prolonged therapy, the possibility of systemic manifestations of negative side effects characteristic of aminoglycosides .

If any of the above negative side effects are detected or their aggravation, as well as if other negative phenomena are found that are not described in the instructions, the patient is obliged to inform her gynecologist about this.

Application instruction of Polygynax (Method and dosage)

The instructions for use recommend using vaginal suppositories Polygynax exclusively locally - intravaginally (inside the vagina). The optimal way to use the drug is carried out in the position of the patient - lying on her back, with the deepest possible introduction of the capsule into the vagina. At 24 hours, the use of the 1st capsule is indicated, preferably in the evening (before going to bed).

The prophylactic therapeutic course is usually limited to 6 days. The course of treatment usually takes 12 days.

If it is necessary to skip the daily administration of capsules for one or more days, the resumption of therapy does not require an increase in the recommended dosages, but continues at the usual daily dose (1 capsule).

Overdose

Cases of overdose when using the therapeutic agent Polygynax have not yet been described. Theoretically, with excessive use of capsules, the possibility of the appearance of side effects inherent in the drug or the aggravation of already observed negative phenomena is allowed.

Interaction

Terms of sale

The drug Polygynax is a prescription drug.

Storage conditions

The maximum possible temperature at which the drug capsules should be stored is 25 ° C.

Best before date

Since the production of capsules - 2 years.

special instructions

Before prescribing therapy using Poligynax capsules, it is necessary to refer the patient to the procedure for taking smear from the vaginal mucosa with further bacteriological analysis , in order to determine the causative agent of the disease and its sensitivity to the effects of the active ingredients of the drug.

The duration of treatment should be limited to the time necessary for complete recovery (do not use the drug longer than necessary). This recommendation is intended to prevent the possibility of sustainability to the drug pathological microorganisms and risk reduction reinfection .

At the entire stage of therapy, the patient is not recommended to use latex barrier agents. (condoms, caps).

A woman undergoing treatment with Poligynax capsules should not interrupt the therapeutic course during menstruation.

The attending physician should warn the patient about the need to convey to him all the information regarding the first manifestation or aggravation of any side effects described in the instructions, or the detection of other negative phenomena observed during the treatment.

The effects of the capsules do not have such a negative impact on the patient's body that could interfere with her work with mechanisms or driving vehicles.

Polygynax's analogs

Analogues of suppositories (capsules) of Polygynax are drugs of different groups and with various active ingredients used for local intravaginal use (suppositories, capsules, creams, tablets), which have the same indications and similar therapeutic effects. These drugs include: , , Vagitsin , Nystatin , , , , Clindes , Milagin , Neotrizol , cervugid , .

The price of Polygynax analogues varies widely and depends on the manufacturer; the dosage form used in the production (vaginal tablets, pessaries, capsules, suppositories, etc.); the number of treatment units in the package; active ingredients involved in the manufacture of the drug and much more. For example, suppositories Synthomycin No. 10 can be purchased for 60-100 rubles; capsules Clindamycin No. 16 - for 150-180 rubles; tablets Terzhinan No. 6 - for 400-450 rubles; candles Pimafucin No. 6 - for 510-550 rubles.

Which is better - Polygynax or Terzhinan?

Although both of these medicinal preparations are used in gynecology for the treatment of similar bacterial and fungal infections, they have a number of significant differences, both in the composition of active antibacterial ingredients ( neomycin ; nystatin ; polymyxin for the first one) and ( neomycin ; nystatin ; ternidazole ; prednisolone for the second), and by dosage form (vaginal capsules for the first) and (vaginal tablets for the second). The route of drug administration is almost identical, the safety profile is approximately at the same level, and the spectrum of action in relation to mushrooms and bacteria sensitive to neomycin approximately the same and in both cases quite wide. However, Polygynax capsules do a better job of microorganisms resistant to the impact neomycin and the tablets Terzhinan more effective in dealing with gardnerella and Trichomonas as well as in the prevention of postoperative complications.

The best criterion for choosing between these drugs is the analogues for certain pathological observed in the patient's disease state, as well as the experience of the doctor prescribing antibacterial and/or antifungal therapy.

children

For use in pediatrics, Laboratoire Innotech International produces a special dosage form of this drug - Polygynax Virgo .

With alcohol

Doctors who actively use this drug in their practice have not come to a consensus about its compatibility with . Some of them are convinced that the combination of any antibacterial drugs with reception alcoholic beverages at best, it neutralizes the effects of treatment, and at worst, it can lead to the formation of various negative complications. Others, relying on the actual absence of the active ingredients of the drug in the systemic circulation, do not see any negative effect in this combination. alcohol for ongoing therapy. It is worth noting that both of them agree on the adverse effects alcohol on the human body, in principle, and do not recommend taking such drinks in any pathological conditions, especially in large quantities.

Polygynax during pregnancy (and lactation)

Despite the fact that the official instructions for the drug do not recommend the use of Polygynax suppositories for in the 1st trimester and with extreme caution allows their appointment in the 2nd trimester and 3rd trimester, some doctors still practice therapy using these vaginal capsules, referring to the almost zero content of the active ingredients of the drug in the systemic circulation. Reviews at pregnancy patients who have ever been treated with this drug in the later stages are mostly positive and talk about the effectiveness of Polygynax in relation to various vaginal infections and safety of its use for the fetus.

However, on the Internet you can also find absolutely negative opinions of women who used such local preparations during pregnancy and subsequently encountered developmental disorders own child. These women attribute the occurrence of the observed pathologies in the infant to the effects of such drugs and warn expectant mothers against their use.

Also, the question of the possibility of prescribing Polygynax capsules for , since the penetration of the active ingredients of the drug into the milk of a nursing mother and their possible effect on the baby has not been clarified for certain. For this reason, doctors recommend lactating women refrain from using Polygynax and similar medicines or stop lactation .

Polygynax is generally a universal remedy. After all, the field of its military operations is not only areas affected by thrush. And vaginitis and another imbalance of the microflora of the vagina, which is very important for many (and me in particular).

• Feedback on a sensitive women's topic, so ... sorry ((for those who expected something completely different in the text ...

Why is Pligynax better than other drugs?

The fact that these vaginal capsules have

Antibacterial, bactericidal and antifungal activity

That is, Polygynax is not a "banal" drug for thrush, but a remedy that helps fight a wide range of problems.

In addition, Polygynax is an antibiotic!

Combined antibiotic.

It contains an aminoglycoside neomycin, polyene antibiotic nystatin and a cyclic polypeptide polymyxin V.

Neomycin sulfate (a first-generation, broad-spectrum antibiotic), polymyxin B sulfate (an antibiotic that primarily targets gram-negative organisms), and nystatin (an antifungal agent)

Is polygynax possible during pregnancy?

There is no single answer here - you can and you can't.

There are restrictions on trimesters - it is contraindicated in the first trimester of pregnancy, and in the II and III trimester it is prescribed only in cases where such use is justified and there are no other ways to solve the problem.

**instruction Polygynax in Ukrainian

The blisters of the drug seem huge and hard to open ... but no, there are no problems with extracting from the foil confinement, the capsules seem to jump out by themselves at the slightest pressure.

Many are afraid of the size of the vaginal capsule

The Polygynax capsule is really just huge! Like ... a pigeon egg, or something ...

For some reason, they reminded me ... vitamins for pregnant horses. Sometimes the feeling that the manufacturer simply does not control the size and does everything to intimidate the pregnant female body even more ... and in these exciting months, it calls for emotions anyway)

But with the introduction, everything is much more comfortable than it seems at first glance.

The egg seems to “slip” by itself, sinking inside without the slightest discomfort. Although many smaller candles are not pleasant to me, it immediately turned out to be exactly the opposite - the large size is more comfortable precisely because of the streamlined shape.

In addition, the capsules do not need to be moistened with water before use, which makes it easier to use than, for example, the same Klin-D.

I had to deal with several such preparations due to the "aggravated microflora", and I will say that these huge "testicles" are one of the most comfortable.

For teenage girls and younger girls, there is a form of Polgynax Virgo with the same active ingredients. The only difference is the spout, which is cut off, and the drug is simply injected inside - that is, the gelatin capsule is not injected inside.

The Polygynax vaginal capsule should only be taken in a supine position, and you should not get up further, as everything dissolves rather quickly ...

What I was most afraid of was burning ... but the capsules did not cause me much discomfort.

**instructions for use Polygynax onRussian

A very sensitive question is how it all "comes out" in the morning.

The capsule dissolves, the shell almost completely melts. So there are a lot of discharges, get ready to catch ... ((

It seems that they cannot be called fat, but it is better to protect underwear with something more serious than a daily one. Moreover, it contains soybean oil and slippery dimethicone ... you can roughly imagine what the greasy-slippery slurry will be like at the exit. Some fabrics may well spoil such a composition ....

Excipients: dimethicone 1000, Tefoz 63, hydrogenated soybean oil, gelatin, glycerin, purified water.

How quickly does Polygynax work?

Surprisingly, the main symptoms are removed very quickly ... and here is a huge temptation - stop treatment prematurely, especially in connection with some inconvenience in the morning .....

The main thing is not to do this, but to bring the treatment to the end.

Polygynax spectrum of action:

Active towards Gram-positive microorganisms: Staphylococcus aureus, Corynebacterium spp.; Gram-negative microorganisms: Enterococcus faecium, Enterobacter aerogenes, Escherichia coli, Haemophilus influenzae, Proteus vulgaris, Klebsiella pneumoniae, Mycobacterium tuberculosis, Pseudomonas aeruginosa, Ureaplasma urealyticum. Has a fungicidal effect on pathogenic fungi, especially yeast-like fungi of the genus Candida albicans, Cryptococcus, Hystoplasma.

According to our feelings - with mixed vaginosis Polygynax manages it is better than with thrush . All the same, this drug removes thrush better.

As for vaginosis - an integrated approach is needed, it is better with such pills.

Polygynax can also be used after surgical interventions.

Or if somehow infection with intestinal infections that take root in the vagina has gone ... and then the vaginal capsules will come in handy.

Minus - Polygynax conflicts with latex products.

That is, some methods of contraception are not suitable during the use of this remedy for thrush ... although, on the days of treatment, contacts with a partner are generally not desirable (!) So this minus is conditional.

Spermicidal contraceptives, by the way, reduce the effectiveness of the drug ... caps will also have to be abandoned.

But there is a big advantage - this is the kind of candles that women can use in critical days. Few drugs can boast of such...

Well, 1 capsule a day (before going to bed) is, of course, almost all candles are like that ...

Price , of course, it bites ... you will have to pay about 200 UAH for Poligynax. (450 rubles), in Russia - and even more expensive - 650-700 rubles.

Producer - Innothera, France

Usage nuances:

Since this is a local antibiotic, along with getting rid of problems, it can bring other smaller problems with it ... remember that if we take antibiotics internally, we can get intestinal dysbacteriosis? And in this case, you need to drink "helping" drugs? ( probiotics, prebiotics, etc.)

So after polygynax, useful lactobacilli can die ... and they need to be restored. True, it is not common for us to prescribe such drugs internally ( that is, to the same place as Polygynax) ... capsules with beneficial bacteria like Vagilak (Vagisan), and everything is done through the mouth

If help comes orally, then not all means will be good in this matter ... there is an opinion that only such a thing can compete with antibiotics. The rest are useless...

Otherwise, the thrush may return ... just because everything useful also died along with the pathogenic microflora after the use of Polygynax capsules.