What is the plague and why is it called the black death?

Plague is a serious infectious disease that leads to large-scale epidemics and often ends in the death of a sick person. It is caused by Iersinia pestis, a bacterium that was discovered at the end of the 19th century by the French scientist A. Yersin and the Japanese researcher S. Kitazato. At the moment, the plague pathogens have been studied quite well. In developed countries, outbreaks of plague are extremely rare, but this was not always the case. The first plague epidemic described in the sources occurred in the 6th century on the territory of the Roman Empire. Then the disease claimed the lives of about 100 million people. After 8 centuries, the history of the plague repeated itself in Western Europe and the Mediterranean, where more than 60 million people died. The third large-scale epidemic began in Hong Kong at the end of the 19th century and quickly spread to more than 100 port cities in the Asian region. In India alone, the plague killed 12 million people. For its severe consequences and characteristic symptoms, the plague is often called the "Black Death". It really spares neither adults nor children and, if left untreated, “kills” more than 70% of infected people.

Plague is now rare. Nevertheless, natural foci are still preserved on the globe, where infectious agents are regularly detected in rodents living there. The latter, by the way, are the main carriers of the disease. Deadly plague bacteria enter the human body through fleas that are looking for new hosts after the mass death of infected rats and mice. In addition, the airborne route of infection transmission is known, which, in fact, determines the rapid spread of the plague and the development of epidemics.

In our country, the plague-endemic regions include Stavropol, Transbaikalia, Altai, the Caspian lowland and the East Ural region.

Etiology and pathogenesis

Plague pathogens are resistant to low temperatures. They are well preserved in sputum and are easily transmitted from person to person by airborne droplets. When a flea bites, a small papule first appears on the affected area of ​​the skin, filled with hemorrhagic contents (skin plague). After that, the process quickly spreads through the lymphatic vessels. They create ideal conditions for the reproduction of bacteria, which leads to the explosive growth of plague pathogens, their fusion and the formation of conglomerates (bubonic plague). It is possible for bacteria to enter the respiratory system with the further development of the pulmonary form. The latter is extremely dangerous, as it is characterized by a very fast current and covers vast territories due to intensive distribution between members of the population. If the treatment of plague begins too late, the disease turns into a septic form that affects absolutely all organs and systems of the body, and in most cases ends in the death of a person.

Plague - symptoms of the disease

Plague symptoms appear after 2 to 5 days. The disease begins acutely with chills, a sharp increase in body temperature to critical levels, a drop in blood pressure. In the future, neurological symptoms join these signs: delirium, impaired coordination, confusion. Other characteristic manifestations of the "black death" depend on the specific form of infection.

• bubonic plague - lymph nodes, liver, spleen increase. The lymph nodes become hard and extremely painful, filled with pus, which breaks out over time. Misdiagnosis or inadequate treatment of plague leads to the death of the patient 3-5 days after infection;
• pneumonic plague - affects the lungs, patients complain of coughing, profuse sputum discharge, in which there are blood clots. If you do not start treatment in the first hours after infection, then all further measures will be ineffective and the patient will die within 48 hours;
• septic plague - the symptoms indicate the spread of pathogens literally throughout all organs and systems. A person dies within a day.

Doctors also know the so-called minor form of the disease. It is manifested by a slight rise in body temperature, swollen lymph nodes and headache, but usually these signs disappear on their own after a few days.

plague treatment

Diagnosis of plague is based on laboratory culture, immunological methods and polymerase chain reaction. If a patient has bubonic plague or any other form of this infection, then he is immediately hospitalized. In the treatment of plague in such patients, the personnel of the medical institution must observe strict precautions. Doctors should wear 3-layer gauze bandages, goggles to prevent sputum from getting on the face, shoe covers and a cap that completely covers the hair. If possible, special anti-plague suits are used. The compartment in which the patient is located is isolated from other premises of the institution.

If a person has bubonic plague, streptomycin is administered intramuscularly 3-4 times a day and tetracycline antibiotics intravenously. In case of intoxication, patients are shown saline solutions and hemodez. A decrease in blood pressure is considered as a reason for emergency therapy and resuscitation in the event of an increase in the intensity of the process. Pneumonic and septic forms of plague require an increase in antibiotic doses, immediate relief of intravascular coagulation syndrome, and the introduction of fresh blood plasma.

Thanks to the development of modern medicine, large-scale plague epidemics have become very rare, and at present the mortality rate of patients does not exceed 5-10%. This is true for those cases when the treatment of plague begins on time and complies with established rules and regulations. For this reason, in case of any suspicion of the presence of plague pathogens in the body, doctors are obliged to urgently hospitalize the patient and warn the authorities involved in controlling the spread of infectious diseases.

Video from YouTube on the topic of the article:

Synthia or "synthetic mycoplasmal mycoids JCVI-syn1.0"

The brainchild of Synthetic Genomics Incorporated (Synthetic Genomics Inc.) was created by order of BP (BP), a bacterium that feeds on oil, however, and other organic matter too ...

This fully artificial cell with a computer-engineered genome does not contain any natural DNA at all. It contains special chains of "watermarks" so that its genome is recognized as artificial. It also has antibiotic resistance.

This new form of life has the ability to reproduce itself and function organically in any cell into which it is introduced. Everything the work was financed by "Synthetic Genomics Incorporated", a company with which BP is in alliance and in which it has a significant share of the assets.

On closer examination, it turned out that it could be an accidental or deliberate use of a broad-spectrum bacteriological weapon that poses a potential threat to life on Earth as such.

Many publications on the English-speaking Internet, as well as videos, indicate that there is a concealment of the true extent of the tragedy at the government level. Small groups of independent researchers and local Internet/radio broadcasts on the subject go largely unnoticed; some of them died under strange circumstances. At the same time, the possible consequences of what could very well be one of the key "moves" in the game to reduce the population of the Earth are so important that it is irresponsible to dismiss this information. Too many incredible coincidences are found in and around this topic.

How to get rid of all this oil?

The oil spilled from the well is deep at the bottom of the Gulf of Mexico. She won't be going anywhere for a long time. Its number is constantly growing. There are no oil plumes. But there are deep oil lakes.

What's left of coral in the Gulf of Mexico.

In an interview with Rick Wells on True News on June 28, 2010, late oil industry expert Matt Simmons to the question of why the US government does not take the solution of the oil crisis in the Gulf of Mexico into its own hands, stated: “BP claims it alone has the only technology to resolve it.”.

For decades, scientists have been zealous in genetic modification, which could increase the ability of natural microbes to eat oil spilled both on land and at sea. But even after obtaining recombinant DNA and splitting the genes of bacteria, positive success with the improvement of natural "oil eaters" was very modest. Although the (advance-announced and publicly made) statement by Craig Venter, the founder of IDCO and Synthetic Genomics, on May 15, 2010, fell on deaf ears of news reporters around the world, it was reported that the press is now calls him "Cynthia". He was referring to some kind of bacterial cell based on Cynthia, which will absorb hydrocarbons more efficiently than any known natural microorganism.

Since the beginning of May 2010, BP has made the decision to continuously spray dispersants like Corexit from aircraft and ships, day and night. This spraying was carried out not only over the bay, but also along the coastline.

So-called dispersants not only break down crude oil into smaller fragments, they also add activating minerals to it so that bacteria can multiply more rapidly and eat oil faster. Such bacteria are called biopurifiers or bioremediators, in this case Cynthia.

Consequences

So how do these new synthetic bio-restorative bacteria from the Gulf interact with humanity? This is completely uncharted and secret territory. We already know how marine mammals such as whales and beluga whales reacted to them. A those who did not leave the affected areas died… along with all other marine fauna and coastal vegetation. While the effects of crude oil on human health are well understood, the effects of dispersants containing artificial oil-eating bacteria are not known. No one has ever done anything like this before, not to mention the incredible scale of the operations being carried out now.

The physical symptoms of "BP flu", "BP goo", "blue flu" or whatever you want to call it, are as unique as the synthetic bacteria used in the bay. Insofar as humanity is based on carbon, then how exactly these artificially created and hungry for hydrogen and carbon bacteria will affect human flesh?
Internal bleeding along with ulcerative skin lesions are typical physical symptoms of the “handwriting” of their computer-generated DNA.

Oil spill disease complaint distribution map showing the most hazardous areas.

For several months, many adults and children who have bathed or walked near the Gulf fall ill with a strange disease for which there are no effective remedies. In short news reports, the death of residents from the so-called. "unknown virus", "blue flu" or "blue plague". And silence... But the Gulf of Mexico through the Atlantic is connected to the whole world ...

"Lisa Nelson of Orange Beach, pc. Alabama is one of the growing number of people sick and dead as a result of the BP disaster. Local physicians have no idea what diagnosis to make or how to treat patients exposed to the combined effects of toxic crude oil and Corexit. The local, regional and state authorities continue to cover up what is happening and do not provide any assistance.”

“There was water in my inflatable boat, and when I turned it over to drain the water, I scratched myself a little; the wound was 2 centimeters long and maybe a millimeter wide. It happened at 8 am. By 4 p.m., the area around the wound began to hurt and become inflamed. The softball-sized patch was the color of a corvette red and pulsed like a marching band rapping. I washed the wound with hydrogen peroxide and smeared it with neosporin. Thought it would be enough to deal with it...

Infection in the wound began typically. Swelling, redness, very intense pain...increased pain. Then "blisters" form, much like burn blisters, only redder, and, believe it or not, much more painful. An even creepier feature of these swellings is that they are the first step in a process that develops like gangrene. Even worse (or comparatively worse) is that half of patients require necrectomy(deep tissue scraping... can you imagine scraping an area that also hurts terribly?), but more often - amputation… The Centers for Disease Control and Prevention reassured me: “Be glad you still have a leg.”

September 29, 2010
CNN news channel: "128 BP workers involved in the cleanup of the spill fell ill; they were required not to go to public hospitals"

"Rain of bacteria": Carnivorous microbes can spread with rain through "bio-aerosols" - "Skin allergy rashes also spread"

Chemist Bob Naman described the brownish, tacky, tarry globules from the BP oil spill that continue to wash up on beaches all along the Gulf Coast:

“They will harm anyone who breaks them in the hand or otherwise comes into contact with them. You can have an open wound and [the contents of the balloon] go straight [into the body]."

"In women, the mucous membrane is much more developed than in men, and they become ill in a more severe form.. They begin vaginal and rectal bleeding. In young children - bleeding from the ears. This stuff destroys red blood cells.". I note that many of these symptoms are not transient and last for several months - if the person's health is able to endure and overcome them.

Mass death of birds in Arkansas (at least 5,000) on New Year's Eve and then near New Orleans in early January (about 500), as well as fish (about 100,000) in a 30-km zone in northern Louisiana, in part of the reporting, is associated with an unknown toxin . It was also reported that "the birds showed signs of trauma to the chest tissue, there were blood clots in the body cavity and extensive internal bleeding" - that is, destruction of blood vessels with hemorrhage under the influence of Corexit? Of course, there are other global factors affecting the biosphere (high methane content in the water of the Gulf, the La Niña ocean-atmospheric phenomenon, weakening of the Earth's magnetic field, etc.), but for the United States, the Gulf of Mexico is most likely dominant.

Given the fact that corexite easily gets into rain clouds and spreads over long distances, and the fact that similar events have already taken place in the south and southeast of the United States in summer, the hypothesis that these "pestilences" are caused by the entry of birds and fish into clouds and under precipitation containing oil-corexite emulsion looks quite reasonable. Especially since diseases and symptoms characteristic of the coastal zone began to be observed in the continental United States- for example, in people who fall under the rain from the clouds brought from the Gulf of Mexico. It is curious that the map of the death of animals agrees well with the map of the alleged evacuation of the population in connection with the disaster in the Gulf, published at the end of June 2010.

Map of the mass mortality of birds and fish in the United States.

More recently, a columnist for the site Sister Mercy told terrible things in the Gulf of Mexico.
And the worst thing is not the pollution of the water area with hydrocarbons. The worst thing is the biological experiments of the British Petroleum company, which is trying to deal with spilled oil by artificially created oil-eating bacteria.

They are the "blue plague" of the Gulf of Mexico.

instead of a preface.

The Gulf Metastases (Link) review in October mentioned BP's use of synthetic "petroleum" bacteria to clean up the spill in the Gulf. On closer examination of the topic, it turned out that we can talk about the accidental or deliberate use of a broad-spectrum bacteriological weapon that poses a potential threat to life on Earth as such. Despite the enormity of the catastrophe, the environmental and economic damage from it, and the considerable number of dead, "nobody had anything for it."

BP got a little finger shaken and the corporation feels quite comfortable and even has a profit of 1.1 billion. pounds sterling for the third quarter of 2010. Link

Many publications on the English-language Internet, as well as videos, indicate that there is a cover-up of the true extent of the tragedy at the government level. Small groups of independent researchers and local Internet/radio broadcasts on the subject go largely unnoticed; some of them died under strange circumstances. At the same time, the possible consequences of what may very well be one of the key "moves" in the game to reduce the population of the Earth are so important that it is irresponsible to dismiss this information. Too many incredible coincidences are found in and around this topic. But about them next time.

So here's the first piece. This article is replete with technical terms, but certainly deserves attention. In their publications and radio broadcasts, researchers in solidarity with the author of the article challenge the scientific community: check our data and conclusions, confirm or refute them, just don't be silent! For several months, many adults and children who have bathed or walked near the Gulf fall ill with a strange disease for which there are no effective remedies. In short news reports, the death of residents from the so-called. "unknown virus", "blue flu" or "blue plague". And silence... But the Gulf of Mexico through the Atlantic is connected to the whole world...

BLUE PLAGUE FROM THE GULF OF MEXICO or STUPID TRYING TO FOOL MOTHER NATURE

It's foolish to try to fool Mother Nature. Those who think they can get away with it may suddenly find that revenge will be far greater than they bargained for. And all because Nature will respond with such short prongs that will shake the very foundations of the earth, as well as life itself. Playing the role of the Creator is a very dangerous game.

In light of its new logo and corporate image campaign, BP wants the public to perceive it in the spirit of its new slogan, which reads "Beyond Petroleum". BP is much more than just an oil company. What will be revealed next regarding BP and its "bigger-than-oil" activities, both before and after the disaster in the Gulf of Mexico, will build a puzzle for the reader in step by step. And when he reads everything here and puts the pieces of the puzzle together, it will become more than obvious to him that BP was trying to fool Mother Nature ... and she is striking back with a vengeance that will affect the whole world. This deadly game is out of control. What began in the Gulf of Mexico in February 2010 has now grown into a man-made biological nightmare of unknown proportions.

Synthetic genomics
(Genomics is the scientific study of the entire DNA sequence of an organism's genome. A genome is the totality of all genetic information contained in an organism's chromosomes, including its genes and DNA sequences.)

On June 13, 2007, BP entered into a long-term research and development contract and made an investment for an undisclosed asset value in a company called Synthetic Genomics Inc., based in Rockville, NY. Maryland. Synthetic Genomics, co-founded by Dr. J. Craig Venter, was to turn genomics-based technology into a revenue stream.

BP/Synthetic Genomics has extracted such DNA from oil-bearing geological formations (more precisely, from biological organisms living in crude oil) and applied the DNA sequencing method to them. In simple terms, this means that they took DNA from the cells of microbes living in underground oil reservoirs, i.e. bacteria or viruses, after which they began to develop them in a laboratory environment in order to identify, isolate and decipher their chemical and genetic properties. In addition to the initial steps of detection and isolation, additional "sequencing techniques" were also applied.

A key aspect of the deal between BP and Synthetic Genomics was the development of biological transfer (transfer) processes for crude oil, which could lead to an increase in the degree of oil recovery. That is, their goal was to develop new microbes with lab-created genomes that could increase the flow of oil and gas extracted from the reservoir. For an oil company like BP, "more oil and gas" from their extraction translates to "more profit." This process is known as microbiological enhanced oil recovery or MPOR (MEOR).

The microbiological method of enhanced oil recovery implies the use of microorganisms for additional extraction of oil products from an oil-bearing deposit. These micro-organisms are introduced there through oil wells so that they produce by-products that stimulate the release of oil. Since such processes help to mobilize the oil and maintain its flow, it is possible to extract large volumes of oil from the well with their help.

Microorganisms produce slippery substances called surfactants (surfactants). These substances break down oil. Since they are naturally produced by biological microorganisms, they are called bio-surfactants. They act in much the same way, detergents that are slippery to the touch, and help oil to more freely exit the host rocks and fractures.

Oil is a thick liquid with a very high viscosity, i.e. it has low fluidity. Microorganisms help break down the molecular structure of crude oil, making it more liquid and easily recoverable.

Microorganisms produce carbon dioxide as a by-product of their life. Over time, this gas accumulates and begins to displace oil, squeezing it out of rocks.

The alliance between BP and Synthetic Genomics has been focused on the development of new micro-organisms with artificially engineered genomes (synthetic DNA) to improve the production of gas and oil reservoirs. The alliance itself was publicly announced on June 13, 2007. About how long ago the agreement on the union itself was actually concluded is classified corporate information.

It is logical to assume that since BP is paying for genetic research to enhance oil recovery and production, it needed to introduce the newly minted microorganisms created as a result of an alliance with Synthetic Genomics in an oil reservoir located under license area 252 in the Mississippi Canyon geological block.

According to the application submitted by BP to the Mineral Resources Management Service (MMS), they were to drill and plug 2 exploration (non-producing) wells, designated as Wells A and B. In the case of increasing current and future production using enhanced oil recovery (MEOR ) exploratory wells are usually used to inject or introduce microorganisms and their nutrient medium into an oil reservoir.

The first exploration well was partially drilled by Transocean in October 2009, but its semi-submersible drilling platform Marinas was damaged by Hurricane Ida and was towed for repairs in late November. On February 3, 2010, the Deepwater Horizon semi-submersible platform began exploration drilling to complete the operation that was not completed by the Marinas installation. On February 13, 2010, BP informed the US Mineral Resources Service that it had encountered uncontrolled gas emissions and large fractures in the base of the well. It was for this reason that she applied there, and on the same day she received permission to liquidate and kill the well.

Shortly thereafter, Deepwater Horizon began drilling another exploration well for BP. The results of this second drilling operation are well known to all of us: the Deepwater Horizon platform was destroyed on April 22, 2010. The only fact that cannot be refuted regarding both exploration wells is the extremely high gas pressure at the outlet of the oil reservoir and the resulting cracks in the ocean floor .

Say hello to Cynthia
In 2003, IDCV successfully synthesized a tiny virus that infects bacteria. And by 2008, the institute team was able to synthesize the bacterial genome. On May 6, 2010, CGID reported that they had already created self-replicating bacterial cells controlled by a chemically synthesized genome, which were called "synthetic mycoplasmal mycoids JCVI-syn1.0". This completely artificial cell with a computer-engineered genome does not contain any natural DNA at all. Researchers from the Canadian ETC Group named her Cynthia. It contains special chains of "watermarks" so that its genome is recognized as artificial, and also has an indicator of resistance to antibiotics.
One can only speculate about the purpose for which this bacterium is endowed with hereditarily programmed resistance to antibiotics.

This new form of life has the ability to reproduce itself and function organically in any cell into which it is introduced. Its DNA is artificial, and it is this synthetic DNA that controls the cell and is one of the building blocks of life. With its computer-engineered DNA, this synthetic bacterial cell is the first of its kind. All funding for the work was provided by Synthetic Genomics Incorporated, a company with which BP is in alliance and in which it has a significant share of the assets.

Indeed, in strict accordance with its newly proclaimed motto, BP has gone far beyond purely oil interests...

And why was the artificial genome watermarked? Similarly, it is made a uniquely identifiable and patented (i.e., privately owned) asset. What happens if a person becomes infected with Cynthia, this dangerous variant of the bacteria? The use of drugs based on penicillin to combat such an infection will not give any effect. Antibiotic resistance is a property of her DNA, so it would be a waste of time.

And what happens if the whole of humanity becomes infected with this self-reproducing life form through direct contact with it or when it enters through the respiratory tract? Will we be exposed to the DNA of these artificial cells floating through the vessels of our bodies? Will Cynthia's cells combine with other bacteria in our body, giving rise to new deadly bacteria?

Since this microorganism is man-made and programmed through a computer, will not electromagnetic radiation be turned on at frequencies to which its genomes are susceptible? There are a lot of questions that are yet to be answered. But the most important thing is this: will we have time to find these answers in time?

Let's continue to collect our mosaic. The picture is slowly beginning to emerge.

How to get rid of all this oil?
The oil spilled from the well is deep at the bottom of the Gulf of Mexico. She won't be going anywhere for a long time. Its quantity is constantly replenished. There are no oil plumes. But there are deep oil lakes.

In an interview with Rick Wells on True News on June 28, 2010, late oil industry expert Matt Simmons, when asked why the US government is not taking the Gulf of Mexico oil crisis into its own hands, stated : "BP claims it alone has the only technology to resolve it." Given their three-year alliance with Synthetic Genomics and the genetic creations they created, it's possible that the US federal corporation in DC has been convinced that BP's breakthrough genomics technologies will be the preferred bet in this game. After all, an oil spill of this magnitude has never happened before.

From a scientific point of view, attempts to control natural microorganisms have always run into problems. In a variety of environmental conditions, they behave too unpredictably. Chemist Chris Reddy of the Woods Hole Oceanographic Institution likened microbes to teenagers because they are just as difficult to control. In contrast, artificial microbial lifeforms like Cynthia are completely controllable through programming of computer-generated DNA.

Environmental microbiologist Kenneth Lee argues that only microbes can eliminate the oil in the ocean, and that it is biodegradation that "cleanses" most of the oil from the environment. History confirms the correctness of his words, but the time required for this can take decades or even longer. We don't have that much time to remove the oil from the bay.

Scientific American magazine writes: “The last and only defense against the ongoing oil spill in the Gulf of Mexico is billions of tiny hydrocarbon-eating microbes. In fact, the primary motive for using over 830,000 gallons of chemical dispersants on a film of oil above and below the surface of the water was to break the oil into smaller droplets that would be easier for bacteria to absorb.”

If only there was some ultra-highly efficient microorganism capable of doing this job much faster and more efficiently (a couple of winks).

It remains to add a few more pieces of the mosaic, and you will see the whole picture.

Dispersant factor
It is difficult to understand why BP made the decision to continuously spray Corexit-type dispersants from aircraft and ships, day and night, from early May 2010. This spraying was carried out not only over the bay, but also along the coastline. Corexit is said to disperse oil into smaller fragments, but is that the only reason for such a massive spraying operation?

Rainwater samples recently taken from the Gulf of Mexico have found naturally occurring minerals such as copper and iron along with nickel, aluminum and magnesium. For the composition of rain clouds formed from a salty ocean, this is very unusual. The only logical explanation is that such elements are supplied to the waters of the bay, from where they with water vapor and fall into rain clouds. And this can happen in the only way: as a result of spraying a substance containing these elements in the air and above the surface of the bay and / or injecting it under the surface of the water.

Are there such components in Corexit? According to the manufacturer (Nalco), no. So these natural elements must be added to what is then sprayed along with Corexit - but why? What is the use of adding elements like copper and iron to sea water? Meanwhile, it is these natural elements with a nutrient medium that are added to the soil in order to accelerate the growth of plants. So why are they added to sea water?

Bacteria actively multiply in nutrient media. Natural minerals are essential building blocks of the nutrient medium in which bacteria thrive. Think of this sprinkling as "watering the bay" to make it a better breeding ground for hungry oil-eating bacteria. So-called dispersants not only break down crude oil into smaller fragments, they also add activating minerals to it so that bacteria can multiply more rapidly and eat the oil faster. Such bacteria are called biopurifiers or bioremediators.

The big picture is starting to take shape. You are almost there.

Cynthia has a cousin.
The only component missing is a new and previously unknown gene for oil-eating bacteria that can survive in low temperatures at great depths - where the lakes of oil and tar are located - so that they can decompose them faster than any known natural bacteria.

In an article published in the journal Science, Terry Hazen and his colleagues at Lawrence Berkeley National Laboratory reported that in late May/early June 2010 they discovered in cold water and underwater oil plumes a previously unknown species of bacteria that eat oil and decompose its accelerated pace.

A few more movements, and our mosaic will be completely formed.

Hurricanes and vaccines from the bowels of genomics
As I stated during our WVP Radio premiere in August, no hurricanes will hit the Gulf of Mexico this year. (14) Since then, none have been and never will be. Otherwise, hurricanes and high-speed atmospheric currents would have carried these synthetic bacteria all over the planet.

They (i.e. BP, BP) have to isolate the biological nightmare they have created until they either find a way to control it or create a vaccine based on artificial microbial genomes to neutralize its effects. Wasn't that what their plan had been from the very beginning?

On October 7, 2010, Synthetic Genomics Incorporated [with equity invested by BP] and IDCV announced the creation of a new company, Synthetic Genomics Waxins Incorporated (SGVI). This private company will focus on developing next-generation vaccines using genome sequencing and IDCV's expertise in artificial genomics, coupled with the intellectual property and business acumen of Synthetic Genomics Incorporated to significantly improve and improve vaccines in development.

How amazing that the BP/Synthetic Genomics alliance now has its own vaccine company for patented immunizations! But what will it cost humanity? It's so profitable: not only to create artificial bacteria, but also to offer a vaccine against them in case there are any problems. When you create bacteria and manipulate their DNA, you know how all this can be stopped. Truly, BP is much more than oil!

“We are excited to use our cutting-edge synthetic genomics technologies to revolutionize vaccine manufacturing,” said Fernanda Gandara, President of EDCI.

Impact on a person

The ETC Group is an international civil society organization based in Ottawa, Canada. In their recent press release, they stated that:

“Synthetic biology is a high-risk field with the goal of making a profit by building organisms from hitherto poorly understood parts. We understand that laboratory-created life forms can break out of it, become biological weapons, and that the use of such forms threatens the existing natural diversity of life forms. Most worryingly, Craig Venter is putting this powerful technology at the service of the most irresponsible and environmentally damaging industry by partnering with corporations like BP and Exxon to accelerate the commercialization of synthetic life forms.”

Here we have scientific confirmation that "a previously unknown species of oil-eating bacteria, in cold water" greedily absorb oil in the bay.

So how do these new synthetic bio-restorative bacteria from the Gulf interact with humanity? This is a completely virgin and secret territory. We already know how marine mammals such as whales and beluga whales reacted to them. And those who did not leave the affected areas died ... along with all other marine fauna and coastal vegetation. While the effects of crude oil on human health are well understood, the effects of dispersants containing artificial oil-eating bacteria are not known. No one has ever done anything like this before, not to mention the incredible scale of the operations being carried out now.

There is some reason why gun-laden soldiers and military local police guard these so-called "dispersants" stored in warehouses and deployment sites all along the Gulf Coast. If competent experts were able to analyze samples of these substances, then the chemical and biological anomalies contained in them - up to unique DNA signatures - would become public. BP still refers to its wizards' brew as Corexit to hide the fact that it's no longer just a branded product from the manufacturer.

The physical symptoms of "BP Flu", "BP Goo", "Blue Flu" or whatever you want to call it, are as unique as the synthetic bacteria used in the Gulf. Since humanity is based on carbon, how exactly will these artificially created and hungry for hydrogen and carbon bacteria affect human flesh?

Internal bleeding along with ulcerative skin lesions are typical physical symptoms of the “handwriting” of their computer-generated DNA.

BP and its paid hangers-on released an artificial biological plague into the Gulf of Mexico, and it got out of hand. The whole world is a victim of their greed and recklessness. Taking on the role of creator, they began to play a very dangerous game with limitless consequences for life as we know it.

Those who allowed and agreed to such a concealment bear the same responsibility as BP for it. Those of us who live in the Gulf Coast must demand from every politician and governmental body at the national and local level to explain why they let this happen and why they allow it to continue. They are all responsible for lying to us and hiding the truth from us.

So, have you completed all the pieces of the puzzle? Do you see the whole picture now?

This is what colonies of artificially transformed bacteria look like

* This article can be reproduced in its entirety or in full, provided that the source is referenced, which is the World Vision portal and a link to an Internet resource under the title of the article. Copyright: Michael Edward and World Vision Portal at: www.worldvisionportal.org

Translation from English
Sister Mercy

plague doctor in the middle ages

For more than a hundred years, people have associated plague with a special disease that claims the lives of millions of people. Everyone knows the damaging ability of the causative agent of this disease and its lightning-fast spread. Everyone knows about this disease, it is so rooted in the human mind that everything negative in life is associated with this word.

What is plague and where does the infection come from? Why does it still exist in nature? What is the causative agent of the disease and how is it transmitted? What are the forms of the disease and symptoms? What is the diagnosis and how is the treatment carried out? Thanks to what kind of prevention in our time it is possible to save billions of human lives?

What is plague

Experts say that plague epidemics were mentioned not only in historical reference books, but also in the Bible. Cases of the disease were regularly recorded on all continents. But of greater interest are not epidemics, but pandemics or outbreaks of infection that are widespread throughout almost the entire territory of the country and cover neighboring ones. In the entire history of the existence of people, they counted three.

1. The first outbreak of plague or pandemic occurred in the VI century in Europe and the Middle East. During its existence, the infection has claimed the lives of more than 100 million people.
2. The second case, when the disease covered a significant territory, was noted in Europe, from where it reached from Asia in 1348. At this time, more than 50 million people died, and the pandemic itself is known in history as the "plague - black death." She did not bypass the territory of Russia.
3. The third pandemic raged at the end of the 19th century in the East, mainly in India. An outbreak began in 1894 in Canton and Hong Kong. A large number of deaths have been recorded. Despite all the precautions from the local authorities, the number of deaths exceeded 87 million.

But it was during the third pandemic that it was possible to carefully examine the dead people and identify not only the source of the infection, but also the carrier of the disease. The French scientist Alexandre Yersin found that a person becomes infected from sick rodents. A few decades later, they created an effective vaccine against the plague, although this did not help humanity completely get rid of the disease.

Even in our time, isolated cases of plague are recorded in Russia, Asia, the USA, Peru, and Africa. Every year, doctors discover several dozen cases of the disease in various regions, and the number of deaths ranges from one to 10 people, and this can be considered a victory.

Where is the plague found now?

The centers of infection in our time are not marked in red on the usual tourist map. Therefore, before traveling to other countries, it is better to consult an infectious disease specialist where plague is still found.

According to experts, this disease has not yet been completely eradicated. In which countries can you get plague?

1. Isolated cases of the disease occur in the United States and Peru.
2. Plague in Europe has practically not been recorded for the past few years, but the disease has not bypassed Asia. Before visiting China, Mongolia, Vietnam and even Kazakhstan, it is better to get vaccinated.
3. On the territory of Russia, it is also better to play it safe, because several cases of plague are recorded here every year (in Altai, Tyva, Dagestan) and it borders on countries that are dangerous for infection.
4. Africa is considered a dangerous continent from the point of view of epidemiology, most of today's severe infections can be contracted here. Plague is no exception; isolated cases of the disease have been recorded here over the past few years.
5. There is an infection on individual islands. For example, just two years ago, a plague struck several dozen people in Madagascar.

The last hundred years of plague pandemics have not been observed, but the infection has not been completely eradicated.

It has long been no secret that many of the most dangerous infections, which include the plague, are being used by the military as biological weapons. During the Second World War in Japan, scientists brought out a special type of pathogen. In terms of its ability to infect people, it surpassed natural pathogens tenfold. And no one knows how the war could have ended if Japan had used this weapon.

Although plague pandemics have not been recorded for the last hundred years, it has not been possible to completely eradicate the bacteria that cause the disease. There are natural sources of plague and anthropurgic, that is, natural and artificially created in the process of life.

Why is infection considered especially dangerous? Plague is a disease with a high lethality rate. Until the creation of the vaccine, and this happened in 1926, the mortality rate from various types of plague was at least 95%, that is, only a few survived. Now lethality does not exceed 10%.

plague agent

The causative agent of the infection is yersinia pestis (plague bacillus), a bacterium of the genus Yersinia, which is part of a large family of enterobacteria. In order to survive in natural conditions, this bacterium had to adapt for a long time, which led to the peculiarities of its development and vital activity.

1. Grows on simple available nutrient media.
2. It happens in different shapes - from filiform to spherical.
3. The plague bacillus in its structure contains more than 30 types of antigens that help it survive in the body of the carrier and humans.
4. Resistant to environmental factors, but instantly dies when boiled.
5. The plague bacterium has several pathogenicity factors - these are exo and endotoxins. They lead to damage to organ systems in the human body.
6. You can fight bacteria in the external environment with the help of conventional disinfectants. Antibiotics also kill them.

Plague transmission routes

Not only humans are affected by this disease, there are many other sources of infection in nature. The sluggish variants of the plague pose a great danger, when the affected animal can overwinter, and then infect others.

Plague is a disease with natural foci that affects, in addition to humans and other creatures, for example, domestic animals - camels and cats. They get infected from other animals. To date, more than 300 species of bacterial carriers have been identified.

Under natural conditions, the natural carrier of the plague pathogen are:

• gophers;
• marmots;
• gerbils;
• voles and rats;
• Guinea pigs.

In urban environments, special types of rats and mice are a reservoir of bacteria:

• pasyuk;
• gray and black rat;
• Alexandrovskaya and Egyptian species of rats.

The carrier of plague in all cases are fleas. Human infection occurs when this arthropod bites, when an infected flea, not finding a suitable animal, bites a person. Just one flea in its life cycle can infect about 10 people or animals. The susceptibility to the disease in humans is high.

How is the plague transmitted?

1. Transmissible or through the bites of an infected animal, mainly fleas. This is the most common way.
2. Contact, which is infected during the cutting of carcasses of sick domestic animals, as a rule, these are camels.
3. Despite the fact that the primacy is given to the transmissible route of transmission of plague bacteria, the alimentary one also plays an important role. A person becomes infected while eating food contaminated with the pathogen.
4. The methods of penetration of bacteria into the human body during plague include the aerogenic route. While coughing or sneezing, a sick person easily infects everyone around them, so they need to be kept in a separate box.

Plague pathogenesis and its classification

How does the causative agent of plague behave in the human body? The first clinical manifestations of the disease depend on the way bacteria enter the body. Therefore, there are different clinical forms of the disease.

Having penetrated into the body, the pathogen with the blood flow penetrates into the nearest lymph nodes, where it remains and safely multiplies. It is here that the first local inflammation of the lymph nodes occurs with the formation of a bubo, due to the fact that blood cells cannot fully destroy bacteria. The defeat of the lymph nodes leads to a decrease in the protective functions of the body, which contributes to the spread of the pathogen in all systems.

In the future, Yersinia affects the lungs. In addition to infection with plague bacteria of the lymph nodes and internal organs, blood poisoning or sepsis occurs. This leads to numerous complications and changes in the heart, lungs, kidneys.

What are the types of plague? Doctors distinguish two main types of the disease:

• pulmonary;
• bubonic.

They are considered the most common variants of the disease, although conditionally, because the bacteria do not affect any particular organ, but gradually the entire human body is involved in the inflammatory process. According to the degree of severity, the disease is divided into mild subclinical course, moderate and severe.

plague symptoms

Plague is an acute natural focal infection caused by Yersinia. It is characterized by such clinical signs as severe fever, damage to the lymph nodes and sepsis.

Any form of the disease begins with general symptoms. The incubation period of the plague lasts at least 6 days. The disease is characterized by an acute onset.

The first signs of plague in humans are as follows:

• chills and almost lightning-fast increase in body temperature up to 39–40 ºC;
• severe symptoms of intoxication - headache and muscle pain, weakness;
• dizziness;
• damage to the nervous system of varying severity - from stunning and lethargy to delirium and hallucinations;
• the patient has impaired coordination of movements.

A typical appearance of a sick person is characteristic - a reddened face and conjunctiva, dry lips and a tongue that is enlarged and lined with a white thick coating.

Due to the enlargement of the tongue, the speech of the plague patient becomes illegible. If the infection proceeds in a severe form, the person's face is puffy with a blue tint or bluish, the face has an expression of suffering and horror.

Symptoms of bubonic plague

The name of the disease itself comes from the Arabic word "jumba", which means bean or bubo. That is, it can be assumed that the first clinical sign of the "black death", which our distant ancestors described, was an increase in lymph nodes that resembled the appearance of beans.

How is bubonic plague different from other variants of the disease?

1. A typical clinical symptom of this type of plague is bubo. What does he represent? - this is a pronounced and painful enlargement of the lymph nodes. As a rule, these are single formations, but in very rare cases their number increases to two or more. The plague bubo is more often localized in the axillary, inguinal and cervical region.
2. Even before the appearance of bubo, a sick person develops soreness that is so pronounced that one has to take a forced position of the body to alleviate the condition.
3. Another clinical symptom of bubonic plague is that the smaller the size of these formations, the more pain they cause when touched.

How are buboes formed? This is a long process. It all starts with the onset of pain at the site of formation. Then the lymph nodes increase here, they become painful to the touch and soldered with fiber, a bubo is gradually formed. The skin over it is tense, painful and becomes intensely red. Within about 20 days, the bubo resolves or reverses.

There are three options for the further disappearance of the bubo:

• long-term complete resorption;
• opening;
• sclerosis.

In modern conditions, with the right approach to the treatment of the disease, and most importantly, with timely therapy, the number of deaths from bubonic plague does not exceed 7-10%.

Symptoms of pneumonic plague

The second most common variant of the plague is its pneumonic form. This is the most severe variant of the development of the disease. There are 3 main periods of development of pneumonic plague:

• elementary;
• peak period;
• soporous or terminal.

In recent times, it was this type of plague that killed millions of people, because the mortality rate from it is 99%.

The symptoms of pneumonic plague are as follows.

More than 100 years ago, the pneumonic form of plague ended in death in almost 100% of cases! Now the situation has changed, which is undoubtedly due to the correct treatment tactics.

How other forms of plague proceed

In addition to the two classic variants of the course of the plague, there are other forms of the disease. As a rule, this is a complication of the underlying infection, but sometimes they occur as primary independent ones.

1. Primary septic form. The symptoms of this type of plague are slightly different from the two variants described above. The infection develops and proceeds rapidly. The incubation period is shortened and lasts no more than two days. High fever, weakness, delirium and agitation are not all signs of a state disorder. Inflammation of the brain and infectious-toxic shock develops, then coma and death. In general, the disease lasts no more than three days. In relation to this type of disease, the prognosis is unfavorable, recovery almost never occurs.
2. An erased or mild course of the disease is observed with a skin variant of the plague. The pathogen enters the human body through broken skin. At the site of the introduction of the plague pathogen, changes are observed - the formation of necrotic ulcers or the formation of a boil or carbuncle (this is inflammation of the skin and surrounding tissue around the hair with areas of necrosis and pus release). Ulcers heal for a long time and a scar gradually forms. The same changes may appear as secondary in bubonic or pneumonic plague.

Plague diagnosis

The first stage in determining the presence of infection is epidemic. But it is easy to make a diagnosis this way when there are several cases of the disease with the presence of typical clinical symptoms in patients. If the plague has not been seen in a given area for a long time, and the number of cases is calculated in units, the diagnosis is difficult.

In the case of the onset of infection, one of the first steps in determining the disease is the bacteriological method. If plague is suspected, work with biological material to detect the pathogen is carried out under special conditions, because the infection spreads easily and quickly in the environment.

Almost any biological material is taken for research:

• sputum;
• blood;
• puncture buboes;
• examine the contents of ulcerative skin lesions;
• urine;
• vomit masses.

Almost everything that the patient secretes can be used for research. Since the plague in humans is severe and the person is very susceptible to infection, the material is taken in special clothes, and inoculation on nutrient media in equipped laboratories. Animals infected with bacterial cultures die in 3–5 days. In addition, when using the method of fluorescent antibodies, bacteria glow.

Additionally, serological methods for the study of plague are used: ELISA, RNTGA.

Treatment

Any patient with suspected plague is subject to immediate hospitalization. Even in the case of the development of mild forms of infection, a person is completely isolated from others.

In the distant past, the only method of treating the plague was cauterization and processing of buboes, their removal. In an attempt to get rid of the infection, people used only symptomatic methods, but to no avail. After identifying the pathogen and creating antibacterial drugs, not only the number of patients decreased, but also complications.

What is the treatment for this disease?

1. The basis of treatment is antibiotic therapy, tetracycline antibiotics are used in the appropriate dose. At the very beginning of treatment, the maximum daily doses of drugs are used, with their gradual decrease to the minimum in case of normalization of temperature. Before starting treatment, the sensitivity of the pathogen to antibiotics is determined.
2. An important step in the treatment of plague in humans is detoxification. Patients are given saline solutions.
3. Symptomatic treatment is used: diuretics are used in case of fluid retention, hormonal substances are used.
4. Use therapeutic anti-plague serum.
5. Along with the main treatment, supportive therapy is used - heart drugs, vitamins.
6. In addition to antibacterial drugs, local drugs for plague are prescribed. Plague buboes are treated with antibiotics.
7. In the case of the development of a septic form of the disease, plasmapheresis is used daily - this is a complex procedure for cleaning the blood of a sick person.

After the end of treatment, after approximately 6 days, conduct a control study of biological materials.

Plague Prevention

The invention of antibacterial drugs would not solve the problem of the emergence and spread of pandemics. This is just an effective way to cope with an already existing disease and prevent its most formidable complication - death.

So how did you defeat the plague? - after all, isolated cases per year without declared pandemics and the minimum number of deaths after an infection can be considered a victory. An important role belongs to the correct prevention of the disease. And it began the moment the second pandemic arose, back in Europe.

In Venice, after the second wave of the spread of the plague, back in the 14th century, while only a quarter of the population remained in the city, the first quarantine measures were introduced for arrivals. Ships with cargo were kept in the port for 40 days and the crew was monitored to prevent the spread of infection so that it did not enter from other countries. And it worked, no new cases of infection were noted, although the second plague pandemic had already claimed most of the population of Europe.

How is infection prevention carried out today?

1. Even if isolated cases of plague occur in any country, all those arriving from there are isolated and observed for six days. If a person has some signs of the disease, then prophylactic doses of antibacterial drugs are prescribed.
2. The prevention of plague includes the complete isolation of patients with suspected infection. People are not only placed in separate closed boxes, but in most cases they try to isolate the part of the hospital where the patient is located.
3. The State Sanitary and Epidemiological Service plays an important role in preventing the occurrence of infection. They annually control the outbreaks of the plague, take water samples in the area, examine animals that may turn out to be a natural reservoir.
4. In the foci of the development of the disease, the destruction of plague carriers is carried out.
5. Measures to prevent plague in the outbreaks of the disease include sanitary and educational work with the population. They explain the rules of behavior for people in case of another outbreak of infection and where to go first.

But even all of the above was not enough to defeat the disease if the plague vaccine had not been invented. It was from the moment of its creation that the number of cases of the disease has sharply decreased, and there have been no pandemics for more than 100 years.

Vaccination

Today, in addition to general preventive measures, more effective methods are used to combat the plague, which helped to forget about the "black death" for a long time.

In 1926, the Russian biologist V. A. Khavkin invented the world's first plague vaccine. From the moment of its creation and the beginning of universal vaccination in the foci of the appearance of infection, plague epidemics have remained far in the past. Who is vaccinated and how? What are its pros and cons?

Nowadays, a lyophilisate or a live dry vaccine against plague is used, this is a suspension of live bacteria, but a vaccine strain. The drug is diluted immediately before use. It is used against the causative agent of bubonic plague, as well as pulmonary and septic forms. This is a universal vaccine. A drug diluted in a solvent is administered in various ways, which depends on the degree of dilution:

• apply it subcutaneously with a needle or needleless method;
• skin;
• intradermally;
• use the plague vaccine even by inhalation.

Prevention of the disease is carried out for adults and children from the age of two.

Indications and contraindications for vaccination

Plague vaccination is done once and it protects for only 6 months. But not every person is vaccinated, certain groups of the population are subject to prevention.

Today, this vaccination is not included as mandatory in the national vaccination calendar, it is done only according to strict indications and only to certain citizens.

Vaccination is given to the following categories of citizens:

• to all who live in epidemically dangerous areas, where the plague occurs in our time;
• health workers whose professional activities are directly related to work in "hot spots", that is, in places where the disease occurs;
• vaccine developers and laboratory workers in contact with bacterial strains;
• prophylactic vaccination is given to people with a high risk of infection, working in the foci of infection - these are geologists, employees of anti-plague institutions, shepherds.

It is impossible to carry out prophylaxis with this drug for children under two years of age, pregnant and lactating women, if a person has already had the first symptoms of plague, and everyone who has had a reaction to a previous vaccine administration. There are practically no reactions and complications to this vaccination. Of the minuses of such prevention, one can note its short effect and the possible development of the disease after vaccination, which is extremely rare.

Can plague occur in vaccinated people? Yes, this also happens if an already sick person is vaccinated or the vaccine turned out to be of poor quality. This type of disease is characterized by a slow course with sluggish symptoms. The incubation period exceeds 10 days. The condition of the patients is satisfactory, so it is almost impossible to suspect the development of the disease. Diagnosis is facilitated with the appearance of a painful bubo, although there is no inflammation of the tissues and lymph nodes around. In the case of delayed treatment or its complete absence, the further development of the disease is fully consistent with its usual classical course.

Plague is currently not a sentence, but another dangerous infection that can be dealt with. And although in the recent past, all people and health workers were afraid of this disease, today, the basis of its treatment is prevention, timely diagnosis and complete isolation of the patient.