Solution for topical application yoks. Instructions for use of spray and solution Yoks

Each bottle of 30 ml contains: povidone-iodine 2.55 g, allantoin 0.03 g;

excipients: levomenthol, citric acid monohydrate, sodium dihydrocitrate, ethanol 96%, propylene glycol, purified water.

Description

Transparent, slightly opalescent red-brown liquid miscible with water.

pharmachologic effect

Indications for use

Disinfection of the oral cavity and pharynx in inflammatory and infectious diseases - tonsillitis, pharyngitis, tonsillo-pharyngitis, tonsillitis, glossitis, aphthae; in preparing the patient for surgery and in the postoperative period; for the treatment of infections of the oral cavity that occur during chemotherapy, as an additional agent for antibiotic therapy of tonsillitis caused by streptococci, with influenza conditions in the prodromal period.

Contraindications

The drug is contraindicated in case of hypersensitivity to iodine or other components of the drug, with hyperthyroidism, with decompensated heart failure, with renal failure, it is contraindicated to use the drug for 2 weeks before and after studies or therapy with radioactive iodine.

The active substance crosses the placental barrier and passes into breast milk, so the drug is contraindicated during pregnancy and lactation.

Yoks spray is contraindicated in children under 8 years of age.

Pregnancy and lactation

Pregnancy

There is no experience of topical use of povidone-iodine in the oral cavity of pregnant women. With vaginal application of povidone-iodine, or with topical application to the skin during pregnancy or during childbirth, congenital hyperthyroidism or struma was found in newborns, so the use of Jox during pregnancy is not recommended.

Lactation

Iodine passes into mother's milk. In the blood and urine of newborns, several times more iodine was found than in their mothers who used povidone-iodine. High serum concentrations can cause hypothyroidism in neonates. For this reason, Yoks is contraindicated for use during lactation.

Dosage and administration

Adults and children over 8 years of age:

Usually used 2-4 times a day, if necessary and more often (after 4 hours): 1-3 injections in the right and left sides of the mouth or directly on the affected area. The interval between individual applications of the drug should be at least 4 hours. The drug can be used a maximum of 6 times a day. The dose of the drug is determined by the attending physician. Do not inhale or swallow the sprayed solution!

Remove the protective cap and install the applicator. Press the applicator 2-3 times so that the solution enters the sprayer and sprays after pressing. After that, place the applicator tube 2-3 cm into the oral cavity, hold your breath and press the cap twice so that one irrigation is carried out to the right and the second to the left. The applicator before and after application is washed with hot water.

Side effect

The drug is well tolerated.

In some cases, hypersensitivity reactions to the drug are observed, a local manifestation of an allergic reaction to iodine (itching, hyperemia, urticaria) is possible, which requires discontinuation of the drug. Rarely, mainly in children, a short-term burning sensation or a feeling of dryness in the oral cavity appeared at the site of application.

Overdose

There is no experience of overdose with proper topical application in the oral cavity or pharynx.

When using an iodine solution inside, acute iodine poisoning is possible.

Symptoms: Initially, patients report a metallic taste in the mouth, vomiting, pain in the stomach and stool disorders. Within 1-2 days, anuria, swelling of the glottis leading to asphyxia, aspiration pneumonia or pulmonary edema appear. In some cases, vascular insufficiency was observed.

Treatment is exclusively symptomatic; first, standard measures are taken to stop absorption from the gastrointestinal tract. The victim is given milk and brewed starch. If the esophagus is not affected, then gastric lavage can be performed. Then activated charcoal and 1% or 5% sodium thiosulfate solution are prescribed, which reduces iodine to iodide. Excretion of absorbed substances can be accelerated by osmotic diuresis. The experience of dialysis in such situations is not described in the literature.

Interaction with other drugs

It is not advisable to use the drug Yoks simultaneously with other antiseptic agents intended for local use. O use in perspiration of the mouth and throat, especially those containing hydrogen peroxide.

The use of Iox leads to false-positive results of a fecal occult blood test. In the study of thyroid function, the values of protein-bound iodine may increase.

Application features

With laryngitis, the drug can be used only in case of emergency.

Trade name of the drug: JOX ® (JOX ®)

International non-proprietary name or grouping name:
Povidone-Iodine + Allantoin&

Dosage form:

topical spray

Compound

Active substances:
Povidone-iodine 2.550 g and allantoin 0.030 g per 30 ml.

Excipients:
levomenthol, citric acid monohydrate, sodium citrate dihydrate, ethanol 96%, propylene glycol, purified water.

Description
Clear or slightly opalescent red-brown liquid, miscible with water.

Pharmacotherapeutic group:

antiseptic

ATC code: A01AD; R02AA15

Pharmacological properties
Combined preparation for topical use in diseases of the oral cavity and ENT organs. On contact with skin or mucous membranes, it releases iodine; has an antiseptic and anti-inflammatory effect.
The drug has a wide spectrum of antimicrobial activity.
Active against bacteria, fungi, viruses, protozoa.

Indications for use
1. Infectious and inflammatory diseases of the oral cavity and pharynx: including tonsillitis, tonsillitis, tonsillopharyngitis, glossitis, stomatitis, aphthae;
2. For the treatment of the oral cavity and pharynx during surgical interventions on the respiratory tract and oral cavity and in the postoperative period;
3. For the treatment of infections of the mouth and throat that occur during chemotherapy;
4. With streptococcal tonsillitis, it is used as an additional remedy for antibiotic treatment.

Contraindications.
- hypersensitivity to iodine and other components of the drug;
- pregnancy and lactation period;
- children under 8 years old;
- dysfunction of the thyroid gland (hyperthyroidism);
- heart failure;
- Duhring's dermatitis herpetiformis;
- simultaneous use of radioactive iodine.

Dosage and administration
locally.
Remove the protective cap and install the applicator. Press the applicator 2-3 times so that the solution enters the sprayer and sprays after pressing. After that, place the applicator tube 2-3 cm into the oral cavity, hold your breath and press the cap twice so that one irrigation is carried out to the right and the second to the left. It is recommended to use Yoks ® spray 2-4 times a day. If necessary, the drug can be used more often, every 4 hours. The applicator is washed with hot water before and after use.

Side effect
Yoks ® Spray is usually well tolerated.
In some cases, hypersensitivity reactions to the drug and an allergic reaction to iodine (itching, hyperemia) are possible, which requires discontinuation of the drug. Prolonged use of the drug can cause the phenomenon of iodism (including: a metallic taste, increased salivation, swelling of the eyes or larynx), upon the appearance of which you should stop using the drug and consult a doctor.

Interaction with other drugs
Simultaneous use of Yoks® with other antiseptic agents intended for topical use in the oral cavity is not recommended. and pharynx, especially those containing hydrogen peroxide, due to drug inactivation.

special instructions
Not intended for oral administration.
Do not inhale or swallow the drug.

Release form
Spray for local use.
30 ml bottles made of PE (polyethylene) or PET (polyethylene terephthalate), equipped with a mechanical atomizer and a cap that protects the atomizer. Each vial, complete with an applicator or an applicator with a swivel lever, is placed in a cardboard box with instructions for use.

Storage conditions
At temperatures from 10 ° C to 25 ° C in a place protected from light. Keep out of the reach of children.

Best before date
4 years.
Do not use after the expiry date stated on the packaging!

Holiday conditions
Without recipe.

Manufacturer
Ivex Pharmaceuticals s.r.o., Czech Republic Ostravska 29, 74770 Opava-Komarov
IVAX Pharmaceuticals s.r.o., Ostravska 29, 74770 Opava-Komarov, Czech Republic

Address for complaints.
119049, Moscow, st. Shabolovka, d. 10, building 2, Business center "Concord"

Among the drugs for the treatment of diseases of the ENT organs, Yoks-spray deserves special attention. It belongs to iodine-containing drugs. Iodine, as an effective antiseptic, is actively used in the medical field and in everyday life.

Yoks is effective for combating various colds and infectious diseases, accompanied by tonsillitis, tonsillitis, inflammation of the mucous membranes of the oral cavity. Available in the form of a solution and spray. The drug is often labeled TEVA.

The tool has a proven effect due to the following main and auxiliary components:

Povidone-iodine is known as a substance used as an iodine carrier. It softens the aggressive effect of the latter on the body. Iodine is present in it at a concentration of 1%. Auxiliary substances serve as a complement to the action of the main ones, have an antiseptic and anti-inflammatory effect. There are no synthetic antiseptic components in Yoks preparation. It is characterized by an iodine taste, has the smell of menthol and alcohol, and has a red-brown tint.

The agent has a pronounced antimicrobial and anti-inflammatory effect, it is indicated for topical use. Effectively inhibits viruses, bacteria, fungi and protozoa. Microorganisms do not have resistance (resistance) to its active substances.

Indications and contraindications

The drug is effective in the development of infections of the oral mucosa, if necessary, preoperative and postoperative treatment of the oral cavity and pharynx. The use of Yoks Teva is possible during the treatment of infectious diseases that develop during chemotherapy.

Due to the likelihood of adverse reactions of the body to the drug, there are restrictions on its use. According to the instructions for use of Yoks spray, contraindications are:

Yoks instruction prohibits the use of the drug in parallel with other iodine-containing agents. It is contraindicated in pregnant women in the early stages, during breastfeeding, with individual intolerance to the components. Despite this, Yoks during pregnancy is often prescribed by specialists. This is due to the small doses of iodine that enter the body, and an insignificant risk of oversaturation with it.

Instructions for use for children allow the use of a spray, but provides for certain restrictions for this category of patients.

Side effects and the likelihood of overdose

Among the possible side effects, the development of allergic reactions and hypersensitivity to the main components is possible. The appearance of local manifestations in the form of itching or hyperemia requires the rejection of the use of Yoks Teva.

Prolonged use of the drug is fraught with the development of iodism. It is accompanied by the following symptoms:

nausea, vomiting and diarrhea;
pain syndrome in the stomach;
metallic taste in the mouth;
swelling of the eyes and throat

Topical application rarely leads to overdose. There is a risk if the solution is ingested. In this case, signs of acute poisoning appear. To alleviate the condition, the patient needs to do a gastric lavage and take an effective enterosorbent.

Application scheme

Teva spray goes on sale in the form of a glass or plastic bottle with a removable applicator. Before using the drug, wash your hands thoroughly, remove the protective cap from the bottle and attach the applicator to the sprayer. During the procedure, the bottle must be kept upright.

The nebulizer is gently inserted into the mouth. Holding your breath, you should press the spray applicator in the desired direction. One or two clicks are enough. After completion of the treatment, the applicator must be rinsed in warm water. Irrigation is carried out during the day from 2 to 5 times.

Throat spray can be equipped with a non-removable spray. In this case, the principle of processing does not change.

Yoks solution is no less effective. It is used to rinse the mouth in the presence of the above diseases. The rinse solution is very easy to prepare: dilute half or a whole teaspoon of the product in boiled warm water. The volume of water must be at least 100 ml. Rinses are carried out with a frequency of once every 4 hours. Avoid getting the solution inside.

When carrying out both types of procedures, one should be careful and careful, since getting the product on clothes leaves traces that are difficult to remove.

Important information! Patient reviews indicate that significant relief occurs 2-3 days after the start of the treatment course. A particularly good effect is the alternation of irrigation with rinsing.

Analogues, cost and storage conditions

There are 2 analogues of Yoks, the use of which is advisable for ENT diseases - aerosols Lugol and Yodinol. Both of them have a composition similar to Yoks. Lugol contains glycerol, which gently envelops the mucous membranes of the oral cavity. Iodinol is produced in the form of a water-alcohol solution of iodine. Lugol is a good analogue, while its cost is lower.

Pharmacies are allowed to dispense the drug without a doctor's prescription. The spray is sold in 30 ml polyethylene bottles, the solution is in 50 or 100 ml glass bottles. The price of the drug ranges from 188 to 270 rubles. Regular holding of promotions in online pharmacies allows you to profitably buy Yoks using promotional codes .

P NO 14300/01

Trade name of the drug: JOX ® (JOX ®)

International non-proprietary name or grouping name:
Povidone-Iodine + Allantoin&

Dosage form:

topical solution

Compound:

Active substances:
Povidone-iodine 4.250 g and allantoin 0.050 g in 50 ml of solution. Povidone-iodine 8.500 g and allantoin 0.100 g in 100 ml of solution.

Excipients:
levomenthol, citric acid monohydrate, sodium citrate dihydrate, ethanol 96%, propylene glycol, purified water - up to the required volume of the drug in the package.

Description
Clear or slightly opalescent red-brown liquid, miscible with water.

Pharmacotherapeutic group:

antiseptic

ATC code: A01AD; R02AA15

Pharmacological properties

Combined preparation for topical use in diseases of the oral cavity and ENT organs. On contact with skin or mucous membranes, it releases iodine; has an antiseptic and anti-inflammatory effect.
The drug has a wide spectrum of antimicrobial activity.
Active against bacteria, fungi, viruses, protozoa.

Contraindications.

hypersensitivity to iodine and other components of the drug;

pregnancy and lactation period;

children under 6 years old;

dysfunction of the thyroid gland (hyperthyroidism);

heart failure; dermatitis herpetiformis Dühring;

simultaneous use of radioactive iodine. Dosage and administration locally.
Dilute the drug solution with water in a ratio of 1:20 - 1:40 (i.e. from 2.5 ml to 5 ml using the measuring cap enclosed in the package or 1/2-1 teaspoon in 100 ml of water). Rinse the mouth or throat with the diluted solution.
It is recommended to use Yoks ® solution 2-4 times a day, if necessary, the drug can be used more often up to 6 times a day. The minimum intervals between rinses are 4 hours. Side effect
Yoks ® solution is usually well tolerated.
In some cases, hypersensitivity reactions to the drug and an allergic reaction to iodine (itching, hyperemia) are possible, which requires discontinuation of the drug.
Prolonged use of the drug can cause the phenomenon of iodism (including a metallic taste, increased salivation, swelling of the eyes or larynx), if it appears, stop using the drug and consult a doctor. Interaction with other drugs
It is not recommended to use the drug Yoks ® simultaneously with other antiseptic agents intended for topical use in the oral cavity and pharynx, especially those containing hydrogen peroxide, due to inactivation of the drug. special instructions
Not intended for oral administration.
Do not inhale or swallow the drug.
The drug contains about 19% ethanol. Release form
Solution for local use.
50 and 100 ml in dark glass bottles with a propylene screw cap with first opening control and a measuring cap. Each bottle, along with instructions for use, is placed in a cardboard box. Storage conditions
At temperatures from 10 ° C to 25 ° C in a place protected from light. Keep out of the reach of children. Best before date
5 years.
Do not use after the expiry date stated on the packaging! Holiday conditions
Without recipe. Manufacturer
Ivex Pharmaceuticals s.r.o., Czech Republic
Ostravska 29, 74770 Opava-Komarov
IVAX Pharmaceuticals s.r.o., Ostravska 29, 74770 Opava-Komarov, Czech Republic Claims address. 119049, Moscow, st. Shabolovka, d. 10, building 2, Business center "Concord"

Release form, composition and packaging

◊ Solution for topical application red-brown, transparent or slightly opalescent, freely miscible with water.

Excipients: levomenthol - 0.5 g, citric acid monohydrate - 0.1 g, sodium citrate dihydrate - 0.1 g, ethanol 96% - 10 g, propylene glycol - 15 g, purified water - 50 g.

50 ml - dark glass bottles with a measuring cap (1) - packs of cardboard.
50 ml - dark glass bottles (1) - packs of cardboard.

pharmachologic effect

A drug with antimicrobial and anti-inflammatory action for topical use in diseases of the oral cavity and in ENT practice. Releases on contact with skin. It has an antiseptic and anti-inflammatory effect. It has a wide spectrum of antimicrobial activity. Active towards bacteria, viruses, fungi, protozoa.

Pharmacokinetics

Indications

- infectious and inflammatory diseases of the oral cavity and pharynx, incl. tonsillitis, tonsillitis, tonsilopharyngitis, glossitis, stomatitis, aphthae;

- for the treatment of the oral cavity and pharynx during surgical interventions on the respiratory tract and oral cavity and in the postoperative period;

- for the treatment of infections of the mouth and throat that occur during chemotherapy;

- with streptococcal tonsillitis, it is used as an additional remedy in the treatment of antibiotics.

Contraindications

- dysfunction of the thyroid gland (hyperthyroidism);

- insufficiency;

- Duhring's dermatitis herpetiformis;

- simultaneous use of radioactive iodine;

- children's age up to 6 years;

- pregnancy;

- lactation period (breastfeeding);

- hypersensitivity to iodine and other components of the drug.

Dosage

The drug is used to rinse the mouth and throat 2-4 times / day. If necessary, the drug can be used more often - up to 6 times / day. The minimum intervals between rinses are 4 hours.

Before use, dilute the drug solution with water in a ratio of 1:20-1:40 (i.e. from 2.5 ml to 5 ml using the measuring cap included in the package or 1/2-1 teaspoon in 100 ml of water). Rinse the mouth and throat with the diluted solution.

Side effects

In some cases: hypersensitivity reactions to the drug, local manifestations of an allergic reaction to iodine (itching, hyperemia), which may require discontinuation of the drug.

With prolonged use: possible phenomena of iodism (including a metallic taste in the mouth, increased salivation, swelling of the eyes, larynx).

Overdose

Data on overdose of the drug Yoks are not provided.

drug interaction

It is impractical to use the drug Yoks simultaneously with other antiseptic agents for topical use in the oral cavity and pharynx, especially those containing, due to the inactivation of the drug.