Dentamet dental gel: indications, instructions, reviews. Dentamet dental gel: indications, instructions, reviews Synonyms of nosological groups

Latest update of the description by the manufacturer 14.08.2008

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Active ingredient:

ATX

Pharmacological groups

Nosological classification (ICD-10)

Composition and release form

in an aluminum tube 10 or 25 g; in a cardboard pack 1 tube.

Description of the dosage form

Homogeneous gel, from white to white with a yellowish tint.

Pharmacological action

Pharmacological action- antiseptic, antibacterial.

Pharmacodynamics

The effectiveness of the drug is due to the presence of two antibacterial components in its composition:

Metronidazole has an antibacterial effect against anaerobic bacteria that cause periodontal diseases: Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium fusiformis, Wolinella recta, Eikenella corrodens, Borrelia vincenti, Bacteroides melaninogenicus, Selenomonas spp.;

Chlorhexidine is a broad-spectrum antiseptic that has a bactericidal effect against vegetative forms of gram-negative and gram-positive microorganisms, as well as yeast, dermatophytes and lipophilic viruses.

Pharmacokinetics

When applied topically, Dentamet™ gel is practically not absorbed.

Indications for the drug Dentamet

Infectious and inflammatory diseases of periodontal and oral mucosa:

acute and chronic gingivitis;

acute ulcerative-necrotizing gingivitis of Vincent;

acute and chronic periodontitis;

juvenile periodontitis;

periodontal disease complicated by gingivitis;

aphthous stomatitis;

inflammation of the oral mucosa when wearing dentures;

post-extraction alveolitis (inflammation of the socket after tooth extraction);

periodontitis, periodontal abscess (as part of combination therapy).

Contraindications

individual intolerance to metronidazole and other derivatives of nitroimidazole, chlorhexidine;

intolerance to any components included in the drug;

children under 6 years of age.

Use during pregnancy and breastfeeding

Side effects

When using Dentamet™ gel topically, the risk of developing systemic side effects is low, but sometimes headache and allergic reactions (skin rash, itching, urticaria) may occur.

Interaction

Directions for use and doses

Locally, for dental use only.

For adults and children over 6 years of age with gum inflammation (gingivitis), Dentamet ™ is applied to the gum area 2 times a day; it is not recommended to wash off the gel. The duration of treatment is on average 7-10 days. After applying the gel, you should refrain from drinking and eating for 30 minutes.

In case of periodontitis, after removing dental plaque, periodontal pockets are treated with Dentamet™ gel and the gel is applied to the gum area. Exposure time - 30 minutes. The number of procedures depends on the severity of the disease. In the future, the patient can apply the gel independently: Dentamet ™ is applied to the gum area 2 times a day for 7-10 days.

For aphthous stomatitis, Dentamet ™ is applied to the affected area of the oral mucosa 2 times a day for 7-10 days.

To prevent exacerbations of chronic gingivitis and periodontitis, Dentamet™ gel is applied to the gum area 2 times a day for 7-10 days. Preventive courses of treatment are carried out 2-3 times a year.

To prevent post-extraction alveolitis after tooth extraction, the hole is treated with Dentamet™ gel, then the gel is applied on an outpatient basis 2-3 times a day for 7-10 days.

Overdose

There were no cases of drug overdose with topical use.

Special instructions

The use of Dentamet ™ gel does not replace hygienic brushing of teeth, therefore, during the course of treatment with the drug, teeth brushing should be continued.

Storage conditions for the drug Dentamet

At a temperature not exceeding 25 °C.

Keep out of the reach of children.

Shelf life of the drug Dentamet

2 years.

Do not use after the expiration date stated on the package.

Synonyms of nosological groups

ICD-10 rubric	Synonyms of diseases according to ICD-10
A69.1 Other Vincent infections	Angina Vincent
	Angina Plaut-Vincent
	Angina Simanovsky-Plaut-Vincent
	Sore throat, ulcerative membranous
K05.0 Acute gingivitis	Gingivitis
	Acute gingivitis
	Acute ulcerative necrotizing gingivitis Vincent
	Acute ulcerative gingivitis
K05.1 Chronic gingivitis	Chronic gingivitis
K05.2 Acute periodontitis	Periodontal diseases
	Periodontitis
	Acute periodontitis
	Periodontal disease complicated by gingivitis
	Pericoronitis
K05.3 Chronic periodontitis	Periodontal infections
	Chronic periodontitis
	Periodontitis
K05.4 Periodontal disease	Alveolar pyorrhea
	Amphodontosis
	Pyorrhea
	Superficial and deep periodontal disease
	Chronic periodontal disease
K10.3 Alveolitis of the jaws	Alveolitis
K10.3 Alveolitis of the jaws	Post-extraction alveolitis
K12.0 Recurrent oral aphthae	Aphthous stomatitis
	Aphthous stomatitis
	Aphthae
	Aphthae of the oral mucosa
	Bednar afta
	Oral ulceration
	Ulceration of the oral mucosa
	Ulceration of the oral mucosa
	Recurrent aphthous stomatitis
	Aphthous stomatitis
K12.1 Other forms of stomatitis	Angular stomatitis
	Ulcerative-necrotizing stomatitis
	Ulcerative stomatitis
K13.0 Diseases of the lips	Actinic cheilosis
	Inflammation of the mucous membrane of the lips
	Rash on lips
	Glacial erythema of the lips
	Glandular cheilitis
	Zaeda
	Mycotic jam
	Chapped lips
	Cracks in the corners of the mouth
	Cheilitis
	Exfoliative cheilitis
	Erosive cheilitis
Z97.2 Presence of dental prosthetic device (complete) (partial)	Sore gums when wearing dentures
	Dentures
	Ulceration from dentures
	Damage to the mucous membrane when wearing dentures
	Bedsores from removable dentures
	Irritation from dentures
	Irritation of the oral mucosa by dentures and braces
	Sores from wearing dentures
	Ulcers while wearing dentures

Dentamet
Buy Dentamet in pharmacies

DOSAGE FORMS
dental gel

MANUFACTURERS
Altaivitamins (Russia)

GROUP
Combined antimicrobial agents

COMPOUND
Active ingredient: Metronidazole and Chlorhexidine gluconate.

INTERNATIONAL NON-PROPENTED NAME
Metronidazole+Chlorhexidine

SYNONYMS
Metrogyl denta

PHARMACOLOGICAL ACTION
Metronidazole has an antibacterial effect against anaerobic bacteria that cause periodontal diseases: Porphyromonas gingivalis, Prevotella intermedia, P.denticola, Fusobacterium fusiformis, Wolinella recta, Eikenella corrodens, Borrelia vincenti, Bacteroides melaninogenicus, Selenomonas sp. Chlorhexidine is a broad-spectrum antiseptic that has a bactericidal effect against vegetative forms of gram-negative and gram-positive microorganisms, as well as yeast, dermatophytes and lipophilic viruses. When applied topically, Metrogyl Denta gel is practically not absorbed, because the main active ingredients are used in minimal therapeutic concentrations, and their systemic exposure is minimal.

INDICATIONS FOR USE
Infectious and inflammatory diseases of the periodontium and oral mucosa: acute and chronic gingivitis (inflammation of the gums); acute ulcerative-necrotizing gingivitis of Vincent; acute and chronic periodontitis; juvenile periodontitis; periodontal disease complicated by inflammation; aphthous stomatitis; pulpitis; cheilitis; inflammation of the oral mucosa when wearing dentures; post-extraction alveolitis (inflammation of the socket after tooth extraction); periodontitis, periodontal abscess (as part of combination therapy).

CONTRAINDICATIONS
Individual intolerance to metronidazole, chlorhexidine, as well as nitroimidazole derivatives. There is no experience with the use of the drug in pregnant and lactating women.

SIDE EFFECTS
When using Metrogyl Denta gel topically, the risk of developing systemic side effects is low, but sometimes the following may occur: headache, allergic reactions (skin rash, itching, urticaria).

INTERACTION
When applied topically in recommended doses, no systemic interaction of Mentrogil Denta gel with other drugs was detected.

METHOD OF APPLICATION AND DOSAGE
For dental use only! Apply to the gum area 2 times a day. Do not rinse off, refrain from drinking, eating, or brushing your teeth for 30 minutes.

OVERDOSE
There have been no cases of overdose of Metrogyl Denta gel when applied topically.

SPECIAL INSTRUCTIONS
The use of Metrogyl Denta gel does not replace hygienic brushing of teeth, therefore, during the course of treatment with the drug, teeth brushing should be continued.

STORAGE CONDITIONS
Store in a dry place, protected from light, at a temperature from 0 to +25 degrees. WITH.

Instructions for use

Dentamet instructions for use

Dosage form

Compound

Dental gel 1 g

Metronidazole 10 mg

Chlorhexidine bigluconate (20% solution) 5 mg

Pharmacodynamics

Combined antimicrobial drug. The effectiveness of the drug is due to the presence in its composition of such active ingredients as metronidazole and chlorhexidine.

Metronidazole is a nitroimidazole derivative that has antiprotozoal and antibacterial effects against anaerobic protozoa and anaerobic bacteria that cause periodontitis: Porphyromonas gingivalis, Prevotella intermedia, Prevotella denticola, Fusobacterium fusiformis, Wolinella recta, Treponema spp., Eikenella corrodens, Borrelia vincenti B, acteroides melaninogenicus, Selenomonas spp .

Inactive against aerobic bacteria.

The mechanism of action is the biochemical reduction of the 5-nitro group of metronidazole by intracellular transport proteins of anaerobic microorganisms and protozoa. The reduced 5-nitro group of metronidazole interacts with the DNA of microbial cells, inhibiting the synthesis of their nucleic acids, which leads to the death of bacteria.

Chlorhexidine is a disinfectant that is active against a wide range of vegetative forms of gram-negative and gram-positive microorganisms, yeast, dermatophytes and lipophilic viruses. It affects bacterial spores only at elevated temperatures. The bactericidal effect is due to the binding of cations (the result of dissociation of chlorhexidine salt in a physiological environment) with the negatively charged walls of bacterial cells and extramicrobial complexes. In low concentrations, disrupting the osmotic balance of bacterial cells and the release of potassium and phosphorus ions from them, it has a bacteriostatic effect; at high concentrations, the cytoplasmic contents of the bacterial cell are precipitated, which ultimately leads to the death of the bacteria.

Side effects

“Metallic” taste in the mouth, headache, allergic reactions (skin rash, itching, urticaria).

Selling Features

Available without a prescription

Special conditions

Avoid contact with eyes.

Indications

Acute gingivitis;

Vincent's acute necrotizing ulcerative gingivitis;

Chronic edematous gingivitis;

Chronic hyperplastic gingivitis;

Chronic atrophic (desquamative) gingivitis;

Chronic periodontitis;

Periodontal abscess;

Recurrent aphthous (ulcerative) stomatitis;

Gangrenous pulpitis;

Post-extraction alveolitis;

Juvenile periodontitis;

Toothache of infectious origin.

Contraindications

Hypersensitivity (including to metronidazole, chlorhexidine and nitroimidazole derivatives).

Strengthens the anticoagulant effect of warfarin (increasing the time of prothrombin formation).

Concomitant use with disulfiram increases toxicity, which can lead to the development of neurological symptoms.

The antimicrobial activity of metronidazole is reduced when used simultaneously with phenobarbital and phenytoin due to the accelerated metabolism of metronidazole.

Cimetidine inhibits the metabolism of metronidazole, which may lead to increased metronidazole serum concentrations.

Drug interactions

Avoid contact with eyes.

The use of the drug in pregnant and lactating women is undesirable.

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Release form

Compound

For 1 suppository: Active substance - bisacodyl - 10 mg. ;Excipient - fatty acid glycerides (solid fat, vitepsol H15)

Pharmacological effect

Combined antimicrobial drug. The effectiveness of the drug is due to the presence in its composition of such active ingredients as metronidazole and chlorhexidine. ;Metronidazole is a nitroimidazole derivative that has antiprotozoal and antibacterial effects against anaerobic protozoa and anaerobic bacteria that cause periodontitis: Porphyromonas gingivalis, Prevotella intermedia, Prevotella denticola, Fusobacterium fusiformis, Wolinella recta, Treponema spp., Eikenella corrodens, Borrelia vincenti , Bacteroides melaninogenicus, Selenomonas spp. ;Inactive against aerobic bacteria. ;The mechanism of action is the biochemical reduction of the 5-nitro group of metronidazole by intracellular transport proteins of anaerobic microorganisms and protozoa. The reduced 5-nitro group of metronidazole interacts with the DNA of microbial cells, inhibiting the synthesis of their nucleic acids, which leads to the death of bacteria. ;Chlorhexidine is a disinfectant that is active against a wide range of vegetative forms of gram-negative and gram-positive microorganisms, yeast, dermatophytes and lipophilic viruses. It affects bacterial spores only at elevated temperatures. The bactericidal effect is due to the binding of cations (the result of dissociation of chlorhexidine salt in a physiological environment) with the negatively charged walls of bacterial cells and extramicrobial complexes. In low concentrations, disrupting the osmotic balance of bacterial cells and the release of potassium and phosphorus ions from them, it has a bacteriostatic effect; at high concentrations, the cytoplasmic contents of the bacterial cell are precipitated, which ultimately leads to the death of the bacteria.

Indications

acute gingivitis; ;acute necrotizing ulcerative gingivitis of Vincent; ;chronic edematous gingivitis; ;chronic hyperplastic gingivitis; ;chronic atrophic (desquamative) gingivitis; ;chronic periodontitis; ;periodontal abscess; ;recurrent aphthous (ulcerative) stomatitis; ;gangrenous pulpitis; ;post-extraction alveolitis; ;juvenile periodontitis; ;toothache of infectious origin.

Contraindications

hypersensitivity (including to metronidazole, chlorhexidine and nitroimidazole derivatives). ;Caution: pregnancy, lactation period.

Use during pregnancy and breastfeeding

Directions for use and doses

The drug is intended for dental use only! ;Locally, after thoroughly brushing your teeth, rinse your mouth with a soda solution and wipe your gums with a dry cotton ball. Squeeze a small amount of gel onto a toothbrush and apply the gel with a toothbrush to the gums and interdental spaces. After applying the gel, do not rinse your mouth or eat food for 30 minutes. Apply to the gum area 2 times a day. The duration of treatment is on average 7-10 days. ;To prevent the disease, a small amount of gel (the size of a pea) is added to the toothpaste. Preventive courses of treatment are carried out for 2-4 weeks. 1-2 times a year.

Composition and release form of the drug

10 g - tubes (1) - cardboard packs.
25 g - tubes (1) - cardboard packs.

Pharmacological action

Combined drug for local use.

Metronidazole- a nitroimidazole derivative with antiprotozoal and antibacterial effects against anaerobic protozoa and anaerobic bacteria causing: Porphyromonas gingivalis, Prevotella intermedia, Prevotella denticola, Fusobacterium fusiformis, Wolinella recta, Treponema spp., Eikenella corrodens, Borrelia vincenti, Bacteroides melanin ogenicus, Selenomonas spp.

Inactive against aerobic bacteria.

The mechanism of action is the biochemical reduction of the 5-nitro group by intracellular transport proteins of anaerobic microorganisms and protozoa. The reduced 5-nitro group of metronidazole interacts with the DNA of microbial cells, inhibiting the synthesis of their nucleic acids, which leads to the death of bacteria.

- disinfectant, active against a wide range of vegetative forms of gram-negative and gram-positive microorganisms, yeast, dermatophytes and lipophilic viruses. It affects bacterial spores only at elevated temperatures. The bactericidal effect is due to the binding of cations (the result of dissociation of chlorhexidine salt in a physiological environment) with the negatively charged walls of bacterial cells and extramicrobial complexes. In low concentrations, disrupting the osmotic balance of bacterial cells and the release of potassium and phosphorus ions from them, it has a bacteriostatic effect; at high concentrations, the cytoplasmic contents of the bacterial cell are precipitated, which ultimately leads to the death of the bacteria.

Indications

Acute gingivitis; Vincent's acute necrotizing ulcerative gingivitis; chronic edematous gingivitis; chronic hyperplastic gingivitis; chronic atrophic (desquamative) gingivitis; chronic periodontitis; periodontal abscess; recurrent aphthous (ulcerative) stomatitis; gangrenous pulpitis; post-extraction alveolitis; juvenile periodontitis; toothache of infectious origin.

Contraindications

Hypersensitivity (including to metronidazole, chlorhexidine and nitroimidazole derivatives); children under 6 years of age.

With caution: pregnancy, lactation period.

Dosage

For dental use only.

Topically, after thoroughly brushing your teeth, apply to the gums and interdental spaces. Apply 2 times/day.

For the purpose of prevention, a small amount is added to toothpaste.

Side effects

Local reactions:"metallic" taste in the mouth.

Systemic reactions:, allergic reactions (skin rash, itching, urticaria).

Drug interactions

Enhances anticoagulant effect warfarin(increased time of prothrombin formation).

Simultaneous use with disulfiram increases toxicity, which can lead to the development of neurological symptoms.

The antimicrobial activity of metronidazole is reduced when used simultaneously with and phenytoin due to accelerated metabolism of metronidazole.

Cimetidine inhibits the metabolism of metronidazole, which may lead to increased concentrations of metronidazole in the blood serum.

Special instructions

The use of the drug does not replace hygienic brushing of teeth, therefore, during the course of treatment with the drug, teeth brushing should be continued. However, you should not combine applying the gel with toothpaste.

Avoid contact with eyes.