In this article you can find instructions for use medicinal product Kagocel. Feedback from site visitors - consumers - is presented of this medicine, as well as the opinions of specialist doctors on the use of Kagocel in their practice. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications were observed and side effects, perhaps not stated by the manufacturer in the annotation. Analogues of Kagocel in the presence of existing structural analogues. Use for the treatment and prevention of influenza, ARVI and herpes in adults, children, as well as during pregnancy and breastfeeding (lactation). Composition of the drug.
Kagocel- antiviral drug. Interferon synthesis inducer.
Causes the formation in the body of so-called late interferon, which is a mixture of alpha and beta interferons with high antiviral activity. Kagocel causes the production of interferon in almost all cell populations involved in the body's antiviral response: T- and B-lymphocytes, macrophages, granulocytes, fibroblasts, endothelial cells. When taking one dose of Kagocel orally, the titer of interferon in the blood serum reaches maximum values after 48 hours. The body’s interferon response to the administration of the drug Kagocel is characterized by prolonged (up to 4-5 days) circulation of interferon in the bloodstream. The dynamics of interferon accumulation in the intestine when taking the drug orally does not coincide with the dynamics of circulating interferon titers. In the blood serum, the interferon content reaches high values only 48 hours after taking the drug Kagocel, while in the intestines the maximum production of interferon is observed after 4 hours.
The greatest effectiveness in treatment with Kagocel is achieved when it is prescribed no later than the 4th day from the onset of acute infection. IN for preventive purposes the drug can be used at any time, incl. and immediately after contact with the infectious agent.
Compound
Copolymer of gossypol (one of the pigments of cotton, a natural polyphenol, toxic in free form) with carboxymethylcellulose + excipients.
Pharmacokinetics
When taken orally, about 20% of the administered dose of the drug enters the general bloodstream. 24 hours after oral administration, the drug accumulates mainly in the liver, to a lesser extent in the lungs, thymus, spleen, kidneys, lymph nodes. Low concentrations are observed in adipose tissue, heart, muscles, testes, brain, and blood plasma. Low content in the brain is explained by the high molecular weight of the drug, which impedes its penetration through the BBB. It is excreted mainly through the intestines: 7 days after administration, 88% of the administered dose is excreted from the body, including 90% in feces and 10% in urine. The drug was not detected in exhaled air.
Indications
- prevention and treatment of influenza and other acute respiratory viral infections in adults and children aged 6 years and older;
- treatment of herpes in adults.
Release forms
Tablets 12 mg. A special pediatric form of the drug is not noted.
Instructions for use and dosage
The drug is taken orally.
For the treatment of influenza and ARVI, adults are prescribed 2 tablets 3 times a day in the first 2 days, 1 tablet 3 times a day in the next 2 days. A total of 18 tablets per course lasting 4 days.
Prevention of influenza and ARVI is carried out in 7-day cycles: 2 days - 2 tablets 1 time per day, break for 5 days. Then the cycle is repeated. The duration of the preventive course varies from 1 week to several months.
For the treatment of herpes, 2 tablets are prescribed. 3 times a day for 5 days. Total for a course lasting 5 days - 30 tablets
Side effect
- allergic reactions.
Contraindications
- pregnancy;
- lactation period (breastfeeding);
- children under 3 years of age;
- lactase deficiency, lactose intolerance, glucose-galactose malabsorption;
- increased individual sensitivity.
Use during pregnancy and breastfeeding
The drug is contraindicated for use during pregnancy and lactation (breastfeeding).
Kagocel, when prescribed in therapeutic doses, is non-toxic and does not accumulate in the body. The drug does not have mutagenic or teratogenic properties, is not carcinogenic and does not have embryotoxic effects.
Use in children
The drug Kagocel is contraindicated in children under 3 years of age.
For the treatment of influenza and ARVI, children aged 3 to 6 years are prescribed 1 tablet 2 times a day in the first 2 days, 1 tablet 1 time a day in the next 2 days. A total of 6 tablets per course lasting 4 days.
For the treatment of influenza and ARVI, children aged 6 years and older are prescribed 1 tablet 3 times a day in the first 2 days, 1 tablet 2 times a day in the next 2 days. A total of 10 tablets per course lasting 4 days.
In children aged 3 years and older, the prevention of influenza and ARVI is carried out in 7-day cycles: 2 days - 1 tablet 1 time per day, a break for 5 days, then the cycle is repeated. The duration of the preventive course is from 1 week to several months.
Special instructions
To achieve therapeutic effect Taking Kagocel should be started no later than the 4th day from the onset of the disease.
Kagocel combines well with other antiviral drugs, immunomodulators and antibiotics.
Drug interactions
With the simultaneous use of the drug Kagocel with other antiviral drugs, immunomodulators and antibiotics, an additive effect is observed (they enhance the effect of each other).
Analogues of the drug Kagocel
Structural analogues The medicine Kagocel does not have any active ingredients.
Analogues pharmacological group(antiviral agents):
- Avonex;
- Alloferon;
- Altevir;
- Alfaferon;
- Amizon;
- Amiksin;
- Anaferon;
- Anaferon for children;
- Arbidol;
- Acyclovir;
- Bonafton;
- Valaciclovir;
- Valtrex;
- Vivorax;
- Virazol;
- Virolex;
- Viferon;
- Genferon;
- Gerpevir;
- Herpferon;
- Groprinosin;
- Zovirax;
- Ingavirin;
- Interferon;
- Inferon;
- Lavomax;
- Medovir;
- Nevirapine;
- Neovir;
- Oksolin;
- Panavir;
- Reaferon EC Lipint;
- Relenza;
- Remantadine;
- Ribavirin;
- Rimantadine;
- Tamiflu;
- Tiloron;
- Famvir;
- Famciclovir;
- Cyclovir;
- Epigen intimate;
- Epigen labial;
- Ergoferon.
If there are no analogues of the drug for the active substance, you can follow the links below to the diseases for which the corresponding drug helps, and look at the available analogues for the therapeutic effect.
Cold tablets Kagocel are an antiviral immunomodulatory agent. Antiviral agent for colds Kagocel, suitable for adults and children over 3 years old. You can take this drug not only for treatment, but also for the prevention of viral diseases. Let's compare with cheaper analogues and point out the main differences between similar tablets and drugs from different manufacturers.
Antiviral drug Kagocel - how to use the drug for prevention and treatment purposes colds?
General characteristics of the drug
Kagocel tablets belong to immunomodulator drugs, since they active substance stimulates production large quantity interferon - a drug that protects the body from pathogens various diseases, – by all the cells that produce it. These include endothelial cells, lymphocytes, and macrophages.
Taking this drug will help strengthen your body to fight viruses Basics active substance medicine – Kagocel. The component stimulates the production of interferons and also has antimicrobial and antiviral effects. Another property of Kagocel antiviral tablets is the suppression of tumor activity of cells.
The active active element kagocel actively destroys viruses, preventing their further development.
You can take Kagocel in parallel with other medications - antibiotics, antihistamines and antiviral medications. Thanks to this property this drug may be included in complex therapy various viral diseases.
Pay attention! The drug Kagocel stimulates the production of its own interferons without introducing foreign compounds into the body.
The maximum effect of the drug is observed within 5-7 days from the start of administration. After the Kagocel tablet is drunk, the substance Kagocel begins to accumulate in the blood within 24 hours. It penetrates the lymph nodes, which is especially important: it is here in large quantities pathogenic microorganisms are localized.
Indications and contraindications for use
The antiviral drug Kagocel is prescribed to both children and adults. Its use is advisable for diseases such as:
- flu;
- ARVI;
- viral in nature(as part of complex treatment);
- diseases caused by a virus;
- urogenital (as part of complex therapy).
Kagocel medicine is also used to prevent colds.
The use of antiviral tablets Kagocel is prohibited for such conditions and deviations as:
- period of pregnancy, breastfeeding;
- age up to 3 children;
- increased sensitivity to active or auxiliary components medicine;
- intolerance to lactose, glucose and galactose;
- acute lactase deficiency.
Pay attention! When taking the drug Kagocel, you may experience side effects in the form of various allergic reactions.
An overdose of Kagocel is possible if you accidentally take several tablets at once. In this case, you need to drink as much as possible more water(preferably several liters) and induce vomiting.
To get a pronounced effect from Kagocel, you need to start taking it no later than the fourth day from the moment of the first manifestations of the disease.
The product is available from pharmacies without a prescription.
How to take Kagocel for adults?
The use of Kagocel tablets is permitted only from the age of 3 years.
In accordance with the instructions for use, Kagocel tablets for adults should be taken according to the specific schedule below. The duration of treatment depends on the patient's condition.
For the prevention of colds and viral diseases in adults It is recommended to take 2 tablets per day at a time for a week. After 5 days you can repeat the course again.
Important! The duration of taking Kagocel for prevention can last from 7 days to several months and is determined by the attending physician.
If the use of the drug is associated with the treatment of diseases caused by a virus, then the course of treatment will be 5 days, during which you should take 2 tablets three times a day.
Kagocel instructions for use for children
Kagocel for children is prescribed from the age of 3 years.
The regimen for taking Kagocel tablets for children depends on how old the child is. Children aged 3 years should be given one tablet of Kagocel twice a day during the first two days of treatment for influenza, viral diseases or colds. For the next 2 days, children are given one tablet of the drug.
Pay attention! The course of treatment with Kagocel for children over 3 years of age should not exceed 4 days.
According to the instructions for Kagocel tablets, children aged 6 years and older can take one tablet 3 times a day, then one tablet twice a day.
If Kagocel is given to a child to prevent viral or colds, then this should be done as follows: throughout the week, give 2 tablets in the morning (preferably) or evening. This must be followed by a break of at least 5 days.
The cost of Kagocel and analogue drugs that cost less
The price of a package of Kagocel tablets (10 tablets) in pharmacies is about 250 rubles.
You can give a list of analogue drugs that are much cheaper than Kagocel. These include:
- (20 tablets per package) – about 40 rubles;
- (10 tablets) – 200 rubles;
- (10 tablets) – 200 rubles;
- (12 tablets) – 200 rubles;
- (granules) – 85 rubles;
- (10 tablets) – 180 rubles;
- (20 tablets) – 70 rubles.
Important! The question of the advisability of replacing the drug Kagocel with analogue drugs is decided by the doctor.
Comparison of analogue drugs, which is better
Drugs with a similar principle of action are often compared. Let's figure out the difference between these comparisons.
Drugs Kagocel and Arbidol
The question is often asked about which is better - Kagocel tablets or the remedy. To answer it, you need to compare the composition of each of them, as well as the principle of action.
Arbidol tablets contain another active substance, which is umifenovir. In addition to influenza and ARVI, it is used to treat and. Arbidol tablets act directly on the virus, preventing its shell from merging with cell membranes humans and preventing reproduction.
The difference between Kagocel and Arbidol tablets is that the first acts directly on the virus, destroying it, and the second stimulates the immune system to actively fight it.
Comparison of the effectiveness of Kagocel and Amiksin
The active component of Amiksin is tilorone. The mechanism of its action is similar to the action of Kagocel: Amiksin stimulates the formation of interferons of all types and prevents the proliferation of viruses. The product is characterized effective action regarding pathogens of ARVI, influenza, and herpes viruses.
Unlike Kagocel, the maximum concentration of interferon when taking Amiksin is observed after 48 hours.
Kagocel or Antigrippin, which is better?
Antigrippin is homeopathic remedy, which can be taken by children aged 1 year and older. The drug has immunomodulatory, anti-inflammatory and antipyretic effects. A significant drawback of Antigrippin is the lack of quick visible results. That is why it is recommended to take it not as independent remedy treatment of colds, and as part of complex therapy.
In most cases, patients respond positively to the antiviral drug Kagocel after finishing taking it. Autumn and winter are the times when the number of cases of respiratory diseases increases sharply. Few of us like to lie in bed with high temperature and sore throat, coughing and sneezing. Kagocel is one of the many drugs that help fight such diseases.
Description of the drug
Kagocel contains a special substance, a gossypol copolymer, which is designed to increase the body's immune response to the penetration of viruses, which occurs, in particular, when infected with viruses that cause so-called acute respiratory infections. viral diseases(ARVI). Under the influence of this substance immune cells body - lymphocytes and macrophages form special compounds - interferons of alpha and beta types. These compounds are designed to quickly neutralize infectious agents that have entered the body, primarily viruses.
Thanks to this feature, Kagocel belongs to the category of antiviral drugs. However, you should not mix agents that stimulate the production of interferons and agents that act directly on viruses, for example, Remantadine or Tamiflu. They have a slightly different mechanism of action, as well as a list of indications.
What are the advantages of Kagocel? First of all, in its versatility - Kagocel, according to the manufacturer, affects not only influenza viruses, but also viruses that cause ARVI (rhinoviruses, adenoviruses, parainfluenza viruses), herpes viruses. The second advantage of the drug is its low level side effects. Thanks to this feature, Kagocel can also be used to treat children. The third advantage of the drug is its low price. Kagocel is in a more affordable price category than, for example, Tamiflu. One package of ten tablets will cost the consumer approximately 250 rubles. It would also be worth noting that the drug can be used not only for treatment, but also for preventive purposes.
Action speed
Within a few hours after taking the drug, interferon titers in the body begin to increase. During the day, the active substance accumulates in the organs, where the highest concentration of cells is observed immune system– in the spleen, lymph nodes, thymus.
However, Kagocel, as a rule, does not act instantly. When taking Kagocel, the interferon titer reaches its maximum values two days after starting the drug. The maximum effect when taking Kagocel is achieved after 5 days.
Indications
The scope of application of the drug is quite wide. Kagocel is prescribed for the treatment of the following diseases:
- ARVI,
- herpes,
- rotavirus infection.
Kagocel can also be used for prevention viral infections in the autumn-winter period, as well as during epidemics. There are no structural analogues of the drug. Among others similar action Ergoferon, Viferon, Grippferon can be noted.
Side effects and contraindications
Kagocel is quite well tolerated by patients. It does not have a hepatotoxic effect, unlike a number of symptomatic remedies, such as paracetamol. Kagocel does not harm the embryo in the womb, does not penetrate the blood-brain barrier, and is also devoid of carcinogenic properties. However, according to the instructions, side effects in some cases may occur.
The main types of side effects:
- nausea,
- heaviness in the stomach,
- allergic skin rashes,
- systemic allergic reactions.
As stated in the instructions for use, Kagocel is not recommended for use during pregnancy and lactation, for patients suffering from lactose intolerance, as well as for children under 3 years of age.
Kagocel combines well with other types of drugs. This allows it to be used as part of complex therapy infectious diseases. In particular, Kagocel enhances the effect of other immunostimulants and antibiotics. If the drug is used in a therapeutic dose, it is non-toxic and does not accumulate in the body.
Cases of overdose are rare. They may be indicated by symptoms such as pain in the epigastric region, nausea and vomiting. Treatment in this case is symptomatic - sorbents and gastric lavage.
Instructions for use
Kagocel is available in only one dosage form, namely, in the form of tablets with a dosage of 12 g. Although Kagocel is available in pharmacies without a prescription, it must be taken only as prescribed by a doctor. Only a specialist is able to determine the dose of the drug, the duration of the course of treatment, and, in general, the need for the patient to take the drug. If there is any uncertainty, please refer to the instructions for medicine. To achieve maximum effect, Kagocel should be taken no later than 4 days after the onset of the disease.
The usual treatment regimen for infectious diseases: on the first day, take two tablets 3 times a day, and then one tablet 3 times a day. In total, it is recommended to take 18 tablets per course of treatment, and the total recommended duration of the course should not exceed 4 days. When treating cytomegalovirus infection and herpes, the doctor may prescribe Kagocel in a dosage of 2 tablets 3 times a day for 5 days - a total of 30 tablets.
According to the instructions for use, for ARVI, the following dose of Kagocel is prescribed. Children 3-6 years old - one tablet 2 times a day in the first two days after the onset of the disease, in the next two days - one tablet once a day. The total duration of treatment is 4 days. Children 6-10 years old are given 1 tablet 3 times a day for the first two days, and then for another two days, 2 tablets twice a day.
When preventing ARVI and influenza, Kagocel is recommended to be taken in the following dosage - two tablets once a day for two days, then a break for five days. Prevention in children is carried out according to a similar scheme, but instead of two tablets at a time, you should take one tablet. Similar cycles can be repeated several times a year depending on the doctor’s instructions.
It is recommended to swallow the tablet whole with plenty of water. Absorption of tablet contents into gastrointestinal tract occurs regardless of food intake, so Kagocel can be taken both before and after meals.
– a drug with pronounced antiviral, antimicrobial, immunomodulatory effects. The drug stimulates the synthesis of alpha, beta and gamma interferons, the action of which is aimed at inhibiting the production of RNA and viral proteins.
The therapeutic effect after the first dose of Kagocel is observed within 4 hours, after which the level of interferons is maintained for up to 4-5 days. The drug has no toxic effect on the body and does not accumulate in tissues, provided the recommended dosages are followed.
Kagocel is combined with other medications: antibiotics, antiviral and antihistamines, drugs that enhance immunity. Thanks to this, Kagocel is used in complex schemes treatment of viral diseases.
Instructions for use
ATX code
J05AX, Other antivirals
Composition and release form
Tablets, round, biconvex, cream-colored, interspersed. 1 tablet contains kagocel - 12 mg.
Pharmacological action
The central mechanism of action of Kagocel is the ability to induce interferon production. Kagocel causes the formation of late interferon in the human body, which is a mixture of alpha and beta interferons that have antiviral properties.
Kagocel causes the production of interferon in cell populations involved in the body's antiviral response: T- and B-lymphocytes, macrophages, granulocytes, fibroblasts, endothelial cells.
When one dose of Kagocel is taken orally, the interferon titer in the blood serum reaches a maximum after 48 hours. The body's interferon response to Kagocel administration is characterized by prolonged (up to 4-5 days) circulation of interferon in the bloodstream.
The dynamics of interferon accumulation in the intestine when Kagocel is taken orally does not coincide with the dynamics of circulating interferon titers. In the blood serum, interferon production reaches its highest values 48 hours after taking Kagocel, and in the intestine, the maximum interferon production is observed after 4 hours.
Kagocel, when prescribed in therapeutic doses, is non-toxic and does not accumulate in the body. The drug is without mutagenic and teratogenic properties, non-carcinogenic and without embryotoxic effects.
The drug is excreted from the body, as a rule, through the intestines: 7 days after administration, 88% of the administered dose is excreted from the body, including 90% in feces and 10% in urine.
Indications for use of Kagocel
- prevention and treatment of influenza and other acute respiratory viral infections in adults;
- treatment of influenza and other acute respiratory viral infections in children 3 years of age and older;
- treatment of herpes in adults.
Directions for use and dosage
For oral administration.
For adults
For the treatment of influenza and ARVI, 2 tablets 3 times a day are prescribed in the first 2 days, 1 tablet 3 times a day in the next 2 days. For a course lasting 4 days - 18 tablets.
Prevention of ARVI is carried out in 7-day cycles: 2 days - 2 tablets once a day, a break for 5 days, then repeat the cycle. The duration of the preventive course varies from 1 week to several months.
For the treatment of herpes in adults, 2 tablets are prescribed 3 times a day for 5 days. For a course lasting 5 days - 30 tablets.
For children
For the treatment of influenza and ARVI, children 3-6 years old are prescribed 1 tablet 3 times a day in the first 2 days, 1 tablet 2 times a day in the next 2 days. For a course lasting 4 days - 10 tablets.
For the treatment of influenza and ARVI, children 6 years of age and older are prescribed 1 tablet 3 times a day in the first 2 days, 1 tablet 2 times a day in the next two days. Per course - 10 tablets, course duration - 4 days.
Prevention of influenza and ARVI in children 3 years of age and older is carried out in 7-day cycles: two days, 1 tablet once a day, 5 days break, then repeat the cycle. The duration of the preventive course is from one week to several months.
Sometimes an individual preventive course of taking the drug is extended to 5 months.
Contraindications
- pregnancy;
- children under 3 years of age;
- increased individual sensitivity.
- lactase deficiency, lactose intolerance or glucose-galactose malabsorption syndrome.
Side effects
Allergic reactions are possible.
Special instructions for use
Effectiveness in treatment with Kagocel is achieved when the drug is prescribed no later than the 4th day from the onset of acute infection. For preventive purposes, the drug is also used immediately after contact with the infectious agent. Kagocel is combined with other antiviral drugs, immunomodulators and antibiotics.
Drug interactions
With simultaneous use of Kagocel with other antiviral drugs, immunomodulators and antibiotics, an additive effect has been described.
Interaction of Kagocel with alcohol
Kagocel and alcohol do not combine, so you should not drink alcohol while treating with this drug.
Storage conditions
Store in a dry, dark place, out of reach of children, at a temperature not exceeding 25°C.
Best before date
Vacation conditions
Available without a prescription.
Kagotsela price
The average price is 215 rubles.
Kagocel's analogs
- Amizon;
- Amiksin;
- Arbidol;
- Oscillococcinum;
- Remantadine;
- Tamiflu;
- Cycloferon;
- Tsitovir.
Kagocel should not be replaced with another medication due to at will. If there is no prescribed product in the pharmacy network, you should seek advice so that your doctor can select the appropriate drug.
