Festal reception time. Festal - contraindications should be observed. Interaction with other drugs

Festal capsules are an enzyme preparation that normalizes digestion. The composition of the complex is saturated with the main pancreatic enzymes:

lipase;
α-amylase;
protease.

All these substances help:

the liver secretes bile;
absorb fats through the thin walls of the intestines;
reduce gas emissions;
stimulate the synthesis of lipase by the pancreas.

Dosage form

The medicine is produced in India pharmaceutical company Sanofi is in the form of round dragees coated with a white glossy enteric coating. The tablets have a faint vanilla aroma. They are packaged in 2, 4, 6 or 10 aluminum blisters per cardboard boxes. One Festal strip contains 10 capsules. The product is sold in pharmacies without a prescription.

Composition feature

The drug is enteric, 1 tablet contains 192 mg of pancreatin, which replenishes the deficiency of pancreatic enzymes:

lipase 6,000 IU;
starch 4,500 IU;
proteinase 300 IU;
Ox Bile - 25 mg;
Hemicellulase - 50 mg.

The medicinal composition of Festal is saturated additional components:

sodium chloride;
hydroxypropyl methylcellulose;
macrogol 8000;
Eudragit L 100−55;
caustic soda;
titanium dioxide;
hydrous magnesium silicate;
sugar cane;
gum arabic;
gelatin;
glucose;
calcium carbonate.

192-220 mg of pancreatin provides activity: 50 mg of hemicellulose, 25 mg of Ox Bile.

The shell is filled with:

cellacephate;
ethyl vanillin;
castor oil;
cane sugar;
methylparaben;
propylparaben;
gelatin.

The manufacturer also made sure to include:

liquid dextrose;
talc;
calcium carbonate;
acacia resin;
glycerol;
macrogol;
food supplement E171.

More detailed information is available in the following table:

Enteric-soluble dragees	1 capsule
Core
Active substances:
pancreatin	192 mg
(equivalent to amylase - 4500 FIP units; lipase - 6000 FIP units; protease - 300 FIP units)
hemicellulase	50 mg
bile components	25 mg
Excipients: sodium chloride
Shell: cellacephate (cellulose acetate phthalate); ethyl vanillin; castor oil; sucrose; methyl parahydroxybenzoate (methylparaben); propyl parahydroxybenzoate (propylparaben); gelatin; liquid dextrose (liquid glucose); talc; calcium carbonate; acacia gum; glycerol (glycerol); macrogol (polyethylene glycol 6000); titanium dioxide

Pharmacology

Doctors recommend using Festal for exocrine pancreatic insufficiency. The complex effect of the drug is comparable to digestive enzymes physiologically secreted by the pancreas. The product stimulates proteolytic, amylolytic, lipolytic processes.
Photo: Good digestion

Pharmacodynamics and pharmacokinetics

The high benefits of Festal for the liver are achieved:

compensation of the exocrine pancreas;
acceleration of food catabolism;
improving digestion.

Bile extract:

increases concentration bile acids;
stimulates the emulsification of fats;
lipase action;
absorption of fats by the intestinal walls.

Hemicellulose breaks down the shells of plant fibers.

Pancreatic enzymes form a proteolytic effect - the breakdown of fats, proteins and carbohydrates.

Amylase, lipase, protease catalyzes the hydrolysis of fats, forming monoglycerides, glycerol, and FFA.

Proteins take the form of peptides and amino acids. Starch is broken down into:

dextrins;
short chain sugar.

Pancreatic components are reliably protected from destruction by gastric juice, thanks to a special shell that dissolves when it enters the small intestine.

Efficiency of application

Violation of external secretory function, biliary tract, inflammation of the pancreas, flatulence, constipation - the main symptoms signaling pathology of the digestive system. The doctor’s task is to prescribe combination therapy to solve a number of problems:

Diffusion of the liver caused by alcoholic beverages and toxic drugs.
Loss of bile acids, oversaturation of bile with cholesterol.
Reduced cyclic circulation of bile acids, with gallbladder dysbiosis (disturbed motility of the gallbladder), dysbacteriosis, chronic disorder of digestion processes.
Violation of physiological regulation in chronic gastrointestinal diseases - inflammation of the mucous membrane, duodenum, gall bladder.

Taking Festal helps improve food digestion in people with normal function Gastrointestinal tract with poor nutrition, impaired chewing functions, low mobility.

Instructions for use

Before taking Festal, read the instructions. According to information from the official website of the manufacturer Sanofi http://www.sanofi.ru, it is enough to consume one tablet 3 times a day.

Preparing the body for diagnostic examination, it is allowed to use a double dose for a short time (2-3 days) before the procedure. There is no standard course of medication for children. The dosage is prescribed by the attending physician individually.

How to take Festal: before or after meals?

According to the instructions, you should take the medicine with food. Do not chew, drink with water. The duration of treatment is determined by the indications for use of Festal. A short course of 2-3 days will help eliminate indigestion. Maintain stable gastrointestinal function during chronic pathologies and intervention will be helped by a long course of treatment (more than 1 month).

Overdose of Festal capsules

When buying Festal tablets, strictly follow the instructions for use. Overdose threatens:

hyperuricemia;
hyperuricuria.

Reviews often contain complaints about perianal irritation and damage to the oral mucosa. Eliminate undesirable consequences timely discontinuation of the drug, urgent treatment symptoms.

Restrictions

Festal is contraindicated in patients suffering from the following ailments:

Dysfunction, liver inflammation, coma, precoma.
Hyperbilirubinemia.
Impaired release of bile into the intestines, accumulation of bilirubin in the blood, cholelithiasis.
Empyema of the gallbladder, polyetiological syndrome (intestinal obstruction).
Frequent loose stools.

Festal will provide both benefit and harm to the liver if the individual components of the composition are tolerated in childhood under 3 years of age, during pregnancy, cystic fibrosis.

Side effect

To avoid side effects of the Festal drug complex, carefully read the indications for use and take into account possible contraindications. Failure to comply with the instructions will result in negative consequences:

Skin manifestations allergies, sneezing, anaphylaxis, angioedema.
Nausea, diarrhea, painful sensations in the abdomen, vomiting.
Hyperuricemia, hyperuricosuria.
Perianal irritation, ileus, constipation in children.

Photo: How to drink Festal correctly

Drug compatibility

Festal helps to assimilate:

PASK;
sulfonamides;
antibiotics.

Anthracite products rich in calcium carbonate and/or magnesium hydroxide reduce the effectiveness of pancreatin, a digestive enzyme compatible with cimetidine. Pancreatin also negatively affects the work of Acarbose, folic acid. Long-term use of pancreatin blocks the absorption of iron by the intestinal walls.

Pay attention! Experts do not recommend Festal and alcohol - the compatibility of the drug does not affect the functioning of the gastrointestinal tract, but has a negative effect on liver function.

Storage conditions

Store Festal in a place protected from children at a maximum temperature of +25°C. Shelf life - 36 months.

Thank you

Digestive problems happen to almost all of us. As soon as there is a holiday, again a night of overeating and combining incompatible foods..site) believes that getting acquainted with the drug festal and instructions for use would not be superfluous. Festal is an enzyme agent.

Why does our body need festal from time to time?

Digestive enzymes are produced by the pancreas and other digestive organs. Normally, they should be enough to digest everything we eat. But this is normal. We don't always eat what we can eat. An abundance of fatty, heavy, carbohydrate foods makes the pancreas work hard. It may not cope, especially if you have already had problems with this organ or if you load your gastrointestinal tract in this way more than once a year, but periodically. In order to help the pancreas, enzymes can be introduced from outside. It is these enzymes that are found in the preparation Festal.

So, festal contains pancreatin, bile And hemicellulase.
Enzymes found in pancreatin ( lipase, amylase and protease) will help you digest food components such as fats, carbohydrates and proteins. The presence of ox bile in festal improves the processing of all food components, and hemicellulase will help your stomach cope with difficult-to-digest plant fiber. In addition, taking festal activates the production of enzymes by the body itself.

When should I take it?

If your pancreas or other digestive organs cannot cope with their tasks due to inflammation or other diseases, after surgical interventions, radiotherapy, then Festal can help you. Festal is also prescribed for age-related dystrophic changes in the digestive organs. If you have overeaten or are eating incorrectly, then Festal can also help you. If you are temporarily unable to chew food properly or if you are preparing for ultrasound examination or x-ray of the digestive organs, then you should also take Festal.

How to take Festal?

Festal is taken one tablet at a time with food. The dragee does not need to be crushed or chewed. In severe cases, it is necessary to take two tablets. You can take Festal for almost any period of time. If the body does not produce enzymes at all, then Festal can be taken even for many years in a row.

Can Festal cause side effects?

If you take Festal too much large doses, you may have diarrhea, vomiting, or discomfort in the epigastric region. Sometimes festal can cause skin rashes, inflammation of the nasal mucosa, and the flow of tears.

Who should not take Festal?

Festal is prohibited from use when acute form inflammation of the pancreas, as well as in case of exacerbation chronic inflammation pancreas. Festal is not allowed to be used when complex diseases liver, accompanied by an increase in the amount of bilirubin in the blood, with non-infectious hepatitis, with stagnation in the intestines, with empyema of the gallbladder, and also when individual intolerance components.

Warning

Avoid overdoses of Festal. In such cases, your number may increase uric acid in urine and blood plasma. If you accidentally took too much Festal tablets, stop using this drug. Take medications that reduce discomfort.

Festal affects absorption by the body

IN modern world Medicines play a big role in a person's life. Each family has its own first aid kit, and sometimes a huge pharmacy, which contains dozens of medications for many diseases. Almost everyone is sure that if they take just one more pill, the disease will immediately recede. But this approach is wrong.

Any medicine must be taken at a strictly defined time, in required quantities and, of course, only on the recommendation of a doctor. Although many medications can be bought at a pharmacy without a prescription. In this case, you must carefully read the instructions for the drug.

Many people have the drug Festal in their medicine cabinet. It is known that it can quickly help with digestive disorders, for example, on days of heavy holiday feasts.

How to take Festal correctly so that the effect of this medicine is the best? How to take a Festal tablet without harming your body? Is it possible to use this medication systematically? What drugs can it be combined with, and what drugs absolutely cannot? Will Festal help if a person drank alcohol at dinner or in this case this medicine useless?

The drug Festal helps normalize the functioning of the pancreas. It contains enzymes that stimulate the breakdown of food components to a state where they can be absorbed into the blood through the walls of the small intestine.

In addition, Festal maintains the necessary balance of bile in the body, that is, it is able to compensate for its volume in case of liver dysfunction.

Indications for use

This enzyme agent is indicated in the following cases:

restoration of the secretory ability of the pancreas;
dystrophy of the stomach, liver, small intestine and gall bladder;
severe overeating;
to restore metabolism;
for the treatment of chronic pancreatitis and cystic fibrosis.

How to use Festal

The main form of release of Festal is a pill, which contains 192 mg of pancreatin with the enzymatic activity of lipase - 6000 IU FIP, amylase - 4500 IU FIP and protease - 300 IU FIP.

It also contains large bile cattle– 25 mg and hemicellulase – 50 mg.

The daily dose of the drug is 3-6 tablets. Frequency of administration: 3 times a day, 1-2 tablets.
Increasing the dose is possible, but only after consulting a doctor.
Well drug therapy Festal can last from 1-2 weeks to 6-7 months. Its duration depends on the course of the treatment process and its positive therapeutic effect. For some patients, lifelong replacement therapy enzyme preparation, for example, when chronic form pancreatitis.
A one-time use of 1-2 Festal tablets is possible in case of severe overeating.

Recommendations (before or after meals, what to drink, etc.)

In order for everything to be biological active ingredients worked effectively, when taking Festal the following recommendations must be followed:

So that the components of the medicine begin to act immediately It should be taken during or immediately after finishing a meal. The tablets should be taken with a small amount of water.
The tablet should not be chewed, as destruction of the protective shell of the tablet will prevent the enzymes from entering the stomach and small intestine, which means the expected effect will not be achieved.

It should be remembered that when joint use medicines their positive effect on the body may decrease. Thus, drugs containing calcium carbonate or magnesium hydroxide can inhibit the activity of enzymes. These substances reduce stomach acidity levels.

But the components of Festal do not contribute to the absorption of iron into the blood. Therefore, this enzymatic remedy should not be taken with iron-containing medications. People suffering from anemia should also refrain from taking Festal.

Antibiotics, sulfonamide and PAS for joint reception with Festal they are absorbed more efficiently.

Combined use of Festal and alcoholic drinks undesirable because healing effect of the drug decreases sharply. This is due to the fact that enzyme activity increases in an alkaline environment.

Alcohol increases the acidity of the environment in gastrointestinal tract. Therefore, enzyme substances lose their ability to accelerate the breakdown of food components. However, in case of severe overeating, even if alcohol is present in the body, Festal can be taken.

Contraindications and side effects

Festal has a number of contraindications for use:

So the drug is strictly prohibited for patients prone to seizures acute pancreatitis. Additional enzymes can provoke inflammation of the membranes of the pancreas and aggravate the patient’s condition, to the point where he needs surgery.
Festal is also contraindicated in patients predisposed to the formation of gallstones. The enzyme preparation can provoke the movement of stones and sand from this organ into the ducts, and lead to their blockage. As a consequence, the development of hepatosis and liver dysfunction. This may cause an increase in bilirubin in the urine.
The drug is not recommended and for chronic diarrhea, which is caused by insufficient absorption capacity of the walls of the small intestine. Digestive enzymes, included in Festal, will only increase diarrhea.

Anyone taking enzyme supplements should know that uncontrolled reception may lead to the development side effects. First of all, these are malfunctions digestive system, signs of which may include nausea, abdominal pain, and diarrhea.

Long-term therapy with Festal can lead to an increase in plasma uric acid levels and the development of hyperuricosuria.

Festala is considered one of the most safe drugs groups of enzymes. However, during pregnancy and lactation, this medicine should be taken with great caution and under medical supervision.

Most often, pregnant women experience the following negative effects: diarrhea, severe nausea, heartburn, vomiting. Blood tests of such patients often show increased level plasma uric acid levels, which may lead to kidney damage.

Enzyme preparations are not recommended for children under three years of age. In cases where enzyme therapy cannot be avoided, daily norm The dose of the drug should be 1-2 Festal tablets per day. The dosage regimen for children is the same as for adult patients - 3 times a day. It is best if the child takes the medicine while sitting, which facilitates free passage of the drug into the stomach.

You should be extremely careful with enzymes, as well as with other medications, especially when prescribing them to children and pregnant women. Taking them without consulting a gastroenterologist is strictly prohibited.

A specialist will help you choose correct scheme treatment, calculate daily dosage. This will reduce the likelihood negative influence enzyme components on a developing or growing organism. If painful or allergic reactions occur, use of Festal must be stopped immediately.

The key to successful therapy is also proper storage medicines. Festal should be stored in a dry and dark place at a temperature no higher than 20-24°C. Shelf life – 3 years from the date of release. Information about the production date of the medicine can be found on the packaging.

Food is not only a delicacy, it is also a source necessary for the body compounds: proteins, fats, carbohydrates. Enzymes play a huge role in the digestion process. They break down food, as a result of which it is absorbed into the bloodstream and takes part in metabolic reactions. If there are not enough biologically active substances, the normal functioning of the gastrointestinal tract is disrupted, causing abdominal pain, heartburn, diarrhea, nausea, and vomiting. In such cases, Festal will help. It performs a replacement function, replenishing required quantity enzymes.

Features of the composition

Festal – complex drug, it contains several components, as a result of which the remedy is indicated for many diseases.

Lipase is an enzyme involved in the breakdown of fats.
Amylase helps digest carbohydrates.
Proteinase helps break down proteins into amino acids.
Hemicellulase is necessary for the digestion of fiber and coarse fibers.
The components of bile have a bactericidal effect, activate the pancreas’s own enzymes, and are necessary for the emulsification of fats and absorption fat-soluble vitamins.

Attention! Festal contains bovine bile, its composition is as close as possible to human bile, as a result of which the effectiveness of the drug is quite high.

Mechanism of action

The drug begins to act in small intestine. Enzymes eliminate food stagnation by breaking down proteins, fats and carbohydrates. Even one tablet of Festal will help get rid of abdominal pain, heartburn, nausea, feeling of fullness, heaviness.

Also active substances The drug activates the production of its own enzymes by the pancreas. Festal has a dual function: it replaces the lack of enzymes and enhances the production of its own.

When is Festal needed?

In most cases, the drug is prescribed by a doctor. It is included in the treatment protocols for many gastrointestinal diseases. If you overeat, eat fatty, fried foods, you can take the pills yourself. Before you buy Festal, you must carefully read the indications, possible side effects, contraindications.

The drug is prescribed in the following cases:

Chronic pancreatitis. The disease is characterized by insufficient production of enzymes by the pancreas, resulting in bloating, constipation, belching, and heartburn.
After surgical interventions on the stomach, liver, bile ducts or pancreas. IN postoperative period it is necessary to provide rest to these organs.
Abuse of fatty or fried foods, overeating. In some cases, the quantity and activity of enzymes is sufficient, but too much food eaten forces you to take Festal tablets. The body cannot cope with such a load on its own, and digestion becomes difficult. The drug is additional source enzymes.
Inflammatory, toxic, alcoholic diseases liver.
Removal of the gallbladder.
Cystic fibrosis.
Diarrhea (non-infectious origin).
Preparation for ultrasound and x-ray examination.

Contraindications

Festal can not only help the digestive organs, but also cause a deterioration in the condition. To avoid unpleasant situations, the drug should be prescribed by a doctor.

Festal components can cause allergic reaction. If rashes appear on the skin, swelling of the face or limbs, stop taking the drug, after which you need to go to the hospital.
Acute pancreatitis.
Liver failure (hepatic encephalopathy).
Increased amount of bilirubin, jaundice.
Intestinal obstruction.
Children under 3 years old.

Attention! Festal is not prohibited during pregnancy and breastfeeding. However, it should only be taken as prescribed by a doctor.

Interaction with other medications

There are some features that must be taken into account when prescribing the drug.

Impairs the body's absorption of iron, not recommended simultaneous use with iron-containing drugs.
The bioavailability of antibiotics and sulfonamides increases.
Antacids negatively affect the absorption of Festal.

Alcohol reduces the effectiveness of the drug to zero.

Frequency of administration, dose

Only a doctor can determine how long and in what dosage to take Festal.

If the cause is overeating, a single dose of the drug is possible. The recommended dose is 1-2 tablets, which should be taken with a sufficient amount of water. The maximum frequency of administration is 3 times a day. In case chronic diseases digestive system, the doctor independently selects a treatment regimen. The course of treatment can last up to a month, after which the doctor assesses the patient’s condition, and if necessary, treatment continues.

Side effects

If the doctor's recommendations are not followed or the dosage is exceeded, nausea, vomiting, diarrhea, and heartburn may occur. Increased sensitivity to the components of the drug is manifested by rashes, itching, redness of the skin, swelling of the face and neck.

Festal is an enzyme preparation. Compensates for insufficiency of the secretory function of the pancreas and biliary function of the liver. Prescribed by a doctor for disorders of the gastrointestinal tract. Before using Festal, you must study the instructions for use. What it helps with and how to use it correctly for adults, as well as what analogues can be replaced - we will look further in the article.

Composition and release form

The drug Festal represents the clinical-pharmacological group of enzyme medicines. The medicine is produced in the form of a white dragee, with a shiny protective film and a slightly vanilla odor.

Thanks to a special coating, the enzymes remain protected from negative action gastric juice and penetrate the small intestine. The drug can quickly eliminate unpleasant phenomena associated with disruption of digestive processes.

Festal helps dilute fats with water and improves their digestibility. Indicated for use in liver damage, loss of bile acid, disorders of bile formation, bile excretion, diseases of the gastrointestinal tract.

Pharmacological action

Festal is of natural origin, made from bovine bile and contains all the enzymes necessary for digestive processes (hemicellulase, amylase, lipase, protease).

The dragee has lipolytic, amylolytic, proteolytic, choleretic and pancreatic-normalizing effects.

Pancreatin in Festal is one of the main active ingredients of the drug; it contains lipase, protease and amylase, penetrates the small intestine and excellently promotes the rapid breakdown, absorption and excretion of carbohydrates, fats and proteins.
Hemicellulase enzyme, which is in tablets, accelerates the process of digestion of plant fiber and thus increases digestive actions, reduces the formation of gases in the intestines.
Presence of bile acids gives additional features for the correction of biliary insufficiency, which often accompanies chronic pancreatitis.
Bile extract has a choleretic effect, facilitates the absorption of fats and fat-soluble vitamins A, E and K, and promotes the secretion of lipase by the pancreas.
Hemicellulase enzyme promotes the breakdown of plant fiber, which also improves digestive processes, reduces the formation of gases in the intestines.

Before using Festal, carefully read the instructions for its use. See the expiration date of the drug.

What Festal helps with: indications for use

Accepted as aid to improve the functioning of the digestive system

When there are not enough enzymes in the body, the process is disrupted normal operation Gastrointestinal tract and symptoms such as burning, nausea, diarrhea and, in some cases, vomiting occur. With such manifestations, there is a need to help the gastrointestinal tract and take medications.

What do pills help with? The main indications for the use of Festal are insufficiency of the pancreas, accompanied by chronic pancreatitis, as well as biliary insufficiency with impaired digestion of food, flatulence, constipation, and so on.

Main indications for the use of tablets for adults:

disorders of the liver and biliary tract, or dysbacteriosis, cirrhosis;
diagnosed insufficiency of exocrine pancreatic function;
sedentary lifestyle or impaired chewing function;
the need to prepare for an ultrasound or x-ray of the abdominal organs.

The use of Festal is also justified in the case of combination therapy after organ irradiation digestive tract, which led to disruptions in the functioning of these organs.

The drug is used with caution in case of concomitant symptoms, as well as during pregnancy. Before starting to use Festal tablets, it is important to exclude the presence of contraindications.

Instructions for use

Before you start taking Festal tablets, it is important to carefully read the instructions for the drug and pay attention to several features correct use drug.

The tablet must be taken with meals or at the end of a meal. Take the product with a small amount of water without chewing. For the adult population, tablets are prescribed in a dosage of 1 or 2 tablets three times a day. If necessary, the dose can be increased, but only on the recommendation of a doctor.

For adults, Festal is prescribed in a dosage of 1-2 tablets after or during meals. Should be used three times a day.
If Festal is prescribed to prepare for hardware diagnostics, it is taken for 3 days before the examination, 2 tablets 3 times a day.

The duration of treatment can vary from several days (if the digestive process is disrupted due to errors in the diet) to several months or years (if constant replacement therapy is necessary).

The drug is given to children only as prescribed by a doctor. It also determines the method of use of the drug.

Contraindications

There are a number of pathological and physiological conditions the patient’s body, which are contraindications for taking Festal tablets, these include:

acute pancreatitis;
exacerbation of chronic pancreatitis;
liver failure;
hepatitis;
jaundice of mechanical origin;
cholelithiasis;
empyema of the gallbladder;
intestinal obstruction.

Given such a number of contraindications, prescribe yourself self-treatment Festal is not allowed.

Pregnancy and lactation

Festal should be used with caution during pregnancy.

Taking the drug is possible only if the benefit to the mother significantly outweighs the expected harm to the fetus. The same applies to women who are breastfeeding. The method of use and dosage during pregnancy and lactation in each case is determined individually by the doctor.

Side effects for the body

Festal tablets may cause some side effects when taken:

From the digestive system: epigastric pain, diarrhea, nausea, vomiting, decreased synthesis of bile acids.
Increased levels of uric acid in blood plasma.
Hyperuricosuria.
The occurrence of an allergic reaction.

Overdose

Symptoms of overdose are hyperuricemia and hyperuricuria. If symptoms of overdose appear, discontinue the drug and carry out symptomatic therapy.

Interaction with other drugs

The combination of the drug with sulfonamides, antibiotics and iron supplements may have different influence for their absorption.
Antacids containing magnesium hydroxide or calcium carbonate can reduce the effectiveness of Festal.
Simultaneous use with Cimetidine may enhance its effect.

Best before date

Shelf life: 3 years. Store in a dry place, at a temperature not exceeding 25 °C.

Do not use after the expiration date stated on the package.

Conditions for dispensing from pharmacies

Over the counter.

Analogs

These days there are a number similar means belonging to the group of enzyme agents. Those who are constantly forced to take Festal must remember that, despite the interchangeability of some enzyme medications, you do not need to switch to a new drug on your own without consulting a doctor.

Festal's analogues:

enzistal,
digestal,
normoenzyme.

If the presence of pancreatin in the composition is important, then the following drugs are recommended:

pancreatin,
mezim,
Creon.

The enzymes included in Festal and its analogues facilitate the absorption of proteins and carbohydrates in the small intestine, promote the breakdown of fiber, which improves the digestion process and reduces, have a choleretic effect, improve the absorption of fats and fat-soluble vitamins.