Medicines that are prescribed to expectant mothers during the period of bearing a peanut often cause concern in women. How justified are such fears?

Carrying a baby is a responsible and difficult process requiring from female body full return. Frequent stress, the presence of chronic diseases, violations of work from the outside immune system lead to the fact that not always the body's reserves are enough to successfully create a cozy "house" for a little man. In this case, products of the pharmacological industry come to the rescue. Medicines provide support to the female body, helping to maintain pregnancy and endure healthy baby. One of the drugs of this kind is Tranexam, the appointment of which during pregnancy is quite common.

Pregnancy in danger - will help Tranex

Very often, spontaneous termination of pregnancy can be prevented if timely correct correction woman's condition. One of characteristic features the fact that a threat looms over pregnancy is the appearance spotting. Even if the intensity of bleeding is small or there is not red blood, but brown spotting, this condition should by no means be ignored.

The drug Tranexam will help with bleeding during pregnancy, as it makes the blood thicker, increases its clotting. Thanks to this, bleeding can be stopped and in many cases a miscarriage can be avoided. If the threat of a breakdown of the baby does not occur for the first time, there is a diagnosis " habitual miscarriage”, Tranexam can be appointed as prophylactic drug already from the first weeks of waiting for the little one. When prescribing any drug during the bearing of a peanut, and Tranexam was no exception, the question of whether it is possible to drink this drug during pregnancy worries many expectant mothers. A woman should remember that only a doctor can determine the cause of the pathological condition and assess its severity. Often it is not enough just to stop the bleeding, additional progesterone support may be required (Utrozhestan, Duphaston). Therefore, you should not make any independent appointments, especially when it comes to drugs.

Tranexam: instructions for use of the drug during pregnancy

Before starting therapy with any remedy, you must carefully study the instructions for its administration and prescription.

Tranexam during pregnancy - components of the drug

To determine the mechanism of action of the drug, it is necessary to know its composition. The active ingredient of the drug is tranexamic acid. In addition to it, the composition of the drug includes sodium glycolate, microcrystalline cellulose, silicon dioxide .

Tranexam during pregnancy - pharmacokinetics and drug effects

The active ingredients of the drug suppress the active peptides involved in allergic and inflammatory processes. Therefore, Tranexam in injections or tablets during pregnancy is used as:

• Antiallergic agent.
• To reduce foci of inflammation (in particular in the treatment of ENT organs).

In addition, the drug makes the blood thicker, and also accelerates its clotting. These qualities of the drug allow us to talk about its hemostatic properties. highest level drug concentrations are noted 3 hours after ingestion.

Tranexam during pregnancy: indications for use

You don't always have to wait until bleeding starts. A number of symptoms also indicate a possible threat of premature termination of pregnancy. In what cases has Tranexam been used during pregnancy?

• Pulling pain in the abdomen, especially with localization in its lower part.
• The appointment of Tranexam occurs when brown discharge from the genital tract during pregnancy.
• A history of miscarriage, especially early dates baby's expectations.
• inflammatory processes.
• Allergic reactions.
• In addition, if a woman does not experience any complaints, but according to the results of an ultrasound diagnosis, a detachment of the fetal egg is detected or there is an accumulation of blood under the chorion, this picture also often requires medical correction. Tranexam often becomes the drug of choice for hematoma during pregnancy.

Forms of release of the drug Tranexam

The drug is available in two forms - tablet (with a dosage of 250 mg or 500 mg of tranexamic acid - tranexamic acid), as well as in the form of a solution for injection, which is administered by drip. If we are talking about ampoules with Tranexam for droppers during pregnancy, then the content of the active substance in them is 50 mg. The liquid is colorless or slightly brownish. Depending on the packaging, 5 or 10 ampoules can be placed in a box.

Recommendations for the rules of administration and dosage of Tranexam

The final regimen in each case is exclusively a doctor. Indications for which this is prescribed medicine, as well as active ingredients, which are present in it, categorically do not allow self-administration of the drug, as well as setting its dosage. The standard course of treatment with Tranexam tablets during pregnancy involves the appointment of 1 or 2 pills 3-4 times a day. There is no exact answer to the question of how much to drink Tranexam during pregnancy. The duration of treatment and the amount of the drug is determined by the doctor based on the condition of the woman and the possible threat to the baby in her womb. But, given term is at least a week from the date of the onset of bleeding (even if it was a single one).

Tranexam during pregnancy

This drug is safe and approved for use, regardless of the period of bearing the baby. What are the states on different terms waiting for the crumbs is the reason for prescribing the drug?

First trimester and Tranexam

The first weeks of bearing the crumbs are the most important and responsible. And although at this time a woman is especially trying to exclude the influence of drugs, you should not refuse the help of some medicines. Tranexam during early pregnancy can be prescribed if:

• There was bleeding.
• As a means of antiallergic therapy.
• To stop the inflammatory process.
• The appointment of Tranexam can also be made with brown discharge during pregnancy, when the doctor sees a threat of further deterioration of the condition and does not wait for the discovery of full-fledged bleeding.
• In the presence of liver disease.
• In the presence of lesions of the ENT organs - tonsillitis, stomatitis, pharyngitis, laryngitis.
• To alleviate the condition with Quincke's edema.

Second trimester and Tranexam

With the development of pregnancy, the list of drugs approved for use is expanding, therefore, during the second trimester, Tranenxam can be used if there is discomfort and pulling pain in the lower part of the peritoneum, lower back, if there is a threat of termination of pregnancy ahead of time.

Third trimester and Tranexam

And although the onset of the third trimester brings the expectant mother even closer to the moment of meeting with the little one, there is no need to rush, the baby should appear on time, conceived by nature. That is why, if there is a threat of the birth of a premature baby, a woman experiences pain in the lumbar region and abdomen, the doctor can also opt for Tranexam as a means to stabilize the condition of the woman's body. Also, the medicine is prescribed in cases of early aging of the placenta.

Possible side effects from the use of Tranexam during pregnancy

Impact of any medicinal product for each individual organism. The same statement applies to this drug. Regarding the results of using Tranexam during pregnancy, most women's reviews contain information about the successful preservation of the baby and the development of pregnancy according to the timing. However, in some cases, expectant mothers noted side effects, such as the:

• Nausea (in some cases up to vomiting).
• Severe heartburn.
• Weakness and dizziness.

In addition, the annotation to the medication informs about the possible occurrence of allergic reactions (rash, itching, urticaria), the development of tachycardia and thrombosis, visual impairment.

Contraindications to the use of Tranexam during pregnancy

When prescribing any drug, it is important to study in detail the section of its contraindications. This recommendation sounds even more categorical for expectant mothers who are responsible not only for their lives and health, but also for the life of a little man in their womb. Moreover, be sure to inform the doctor about all the chronic ailments that you have. So, regardless of the presence of indications, Traneksam cannot be used by women who have:

• Hypersensitivity to any component of the drug.
• Work disruptions urinary system. This factor important, since the main part of the drug is excreted through it.
• The presence of problems with blood clotting, leading to blockage of blood vessels (thrombosis).
• Expansion of veins (varicose veins), regardless of the "problem prescription" - pathological condition occurred during or before pregnancy.
• Disturbances in the blood supply to the brain.
• If a woman has had a blood transfusion, the use of the drug (especially in the form of injections) is prohibited. Exists high risk thrombus formation.

In addition, the drug is incompatible with tetracycline drugs, hemostatic agents, Diazepam.

Thus, we see that, like any drug, Tranexam has both positive and negative aspects of its use. Among the undeniable "pluses" are the safety of the drug for the baby developing in the womb, the rapid onset therapeutic effect, availability and low cost. The use of Tranexam even with a smear during pregnancy can prevent further serious violations of the course of pregnancy. However, the drug can seriously affect the state of the female body, and therefore it may not always be prescribed. Listen carefully to your doctor's recommendations and be healthy!

What to do if bleeding occurs during pregnancy? Is it possible to use hemostatic drugs, for example, Traneksam? Is it harmful in the early stages, how does it affect the formation of the placenta and blood flow in it?

Tranexamic acid - the main active ingredient of the drug - has a number of useful properties. First of all, the drug is prescribed for its hemostatic and antifibrinolytic effect. The medicine helps not only to stop bleeding, but also supports the formed blood clot, preventing re-bleeding.

Also, the agent has anti-inflammatory and anti-allergic effects, but they are less pronounced than the main effect of the drug.

The drug is available in two main dosage forms - biconvex tablets, and a colorless solution for intravenous administration. In both forms, it is available by prescription, you need to take it strictly according to the doctor's prescription.

The medicinal effect is achieved by interfering with the activity of enzymes of the anticoagulant system - primarily in the activation of plasminogen.

The effect of the drug is manifested systemically, i.e. it increases the overall blood clotting. This should be taken into account for patients who have any disorders in this area.

The active substance is absorbed quickly, evenly distributed throughout all tissues of the body. Does not cross the blood-brain barrier well cerebrospinal fluid its concentration is 10 times lower than plasma. Through the placental barrier, Tranexam also penetrates, so its use during pregnancy must be agreed with the doctor.

Indications for the use of the drug

Tranexam is taken at the risk of bleeding or their presence

The remedy is used to stop and prevent bleeding. V preventive purposes tablets are prescribed to patients with impaired after surgical procedures, with generalized fibrinolysis (which may be a symptom malignant neoplasms), as well as to stop and prevent bleeding in allergic and inflammatory diseases.

V medicinal purposes the remedy is used to stop bleeding caused by previous causes, as well as gynecological, postpartum hemorrhage and bleeding during pregnancy.

A solution for intravenous administration is needed when severe forms fibrinolysis, and surgical interventions in a systemic inflammatory response.

It is used to stop most forms of bleeding, however, it should be borne in mind that the effect of the drug is not instantaneous, and with massive and rapid blood loss, other means should be used.

In obstetrics and gynecology, this remedy is used to stop uterine bleeding associated with diseases of the genital tract, pathologies of pregnancy, postpartum period. The drug penetrates the placental barrier, so it is used when the benefit to the mother is higher than the risk to the fetus.

Can Tranexam be taken during pregnancy?

Among the indications for the use of Tranexam is bleeding during pregnancy. This means that expectant mothers are allowed to use it. However, the drug has a number of negative effects on the fetus and can reduce blood flow in the umbilical arteries. It is used in situations where the benefit to the mother is higher than the risk to the fetus, i.e. It is about saving the life and health of women.

In experiments on animals, no embryotoxic or teratogenic effect has been established, but studies on the effect of Tranexam on the human embryo have not been conducted. However, statistics show that if the medicine is used strictly according to indications, the risk to the fetus is minimal.

Indications for the use of Tranexam in early pregnancy:

• Bloody issues.
• Drawing pains in the lower abdomen.
• Detachment of the fetal egg (diagnosed by ultrasound).
• Prevention of bleeding in the early stages (possible use in healthy women).

Features of the mechanism of action do not allow the drug to provide quick effect. The agent reduces the activity of the anticoagulant system, which is in equilibrium with the coagulation system. This leads to an increase in the activity of coagulation enzymes, the formation of blood clots and a decrease in bleeding activity, its gradual stop. If there is a risk of bleeding, then it is reduced.

More information about the causes of bleeding in early pregnancy can be found in the video:

Simply put, the drug allows you to avoid severe bleeding and its consequences, but to save lives in emergency other means are needed.In the early stages, the medicine is prescribed in order to prevent the onset of placental abruption and bleeding, which in the first trimester of pregnancy can be extremely dangerous for a woman and is almost always fraught with miscarriage.

It is possible to prescribe the drug prophylactically, including in healthy women, if there are no contraindications. Such prophylaxis avoids bleeding and other risks of early pregnancy.Women who lie down for preservation are given the drug intravenously in a hospital. This makes it possible to prevent dangerous complications and achieve a normal pregnancy. During the course of treatment, be sure to follow the diet prescribed by the doctor and limit physical activity.

Dosage and application rules

Tranexam tablets are intended for oral administration. During pregnancy, 250-500 mg (1-2 tablets) are prescribed after meals 3-4 times a day. Maximum daily dosage 3000mg (6 tablets of 500mg or 12 tablets of 250mg). The duration of the course of treatment is until the bleeding stops completely (average - 7 days).

For prophylactic purposes, the drug is taken 1 tablet (250 mg) twice a day for 14 days. For more accurate information, you need to consult a doctor, as an individual dose adjustment may be required. In addition, the health of the expectant mother is not an area where self-medication is acceptable.

A solution for intravenous administration is used only in a hospital for women who are admitted to the hospital with a threat of termination of pregnancy or who are on conservation.

The dosage of the drug is selected depending on the condition of the woman. Both slow or fast drip administration, and jet, if necessary, are allowed.

Before you calculate the required dose, you need to do a series of tests - first of all, kidney function and the condition of the fundus are important. In case of violations glomerular filtration the dose of the drug must be reduced to avoid overdose. The fundus of the eye is an area where side effects associated with impaired blood supply to the retina can occur.

Contraindications for use during pregnancy

The tool should not be used:

• With a tendency to thrombosis. It should be noted that during pregnancy, blood clotting increases under the influence of sex hormones, so Tranexam should be used with caution. If a woman has a history of thrombosis, the drug should be discontinued.
• If there are violations color perception and pathology of the retina, Tranexam can aggravate the patient's condition, so use it in similar situations need with caution.
• The same applies to impaired renal blood flow, microvascular pathologies, placental circulation disorders - all diseases in which capillary blood flow is disturbed.
• The agent is contraindicated in DIC both in the first phase (excessive coagulation) and in the second (depletion of coagulation factors). Subarachnoid hemorrhage is absolute contraindication for the use of Tranexam - in this case, the condition may worsen, increase neurological symptoms. In case of skull injuries in pregnant women, one should make sure that this pathology is absent (according to MRI).
• Hypersensitivity reactions may develop on tranexamic acid, which are also a contraindication to the use of the drug.

Caution should be used when kidney failure- possible accumulation of the active substance due to insufficiently rapid excretion. In this case, it is necessary to reduce the dosage of the drug.

Side effects and their danger for pregnant women

The drug increases blood viscosity - this is its main effect, and it can also cause unwanted adverse reactions in the form of impaired blood flow in small vessels. Often at reception there are the disturbances of visual acuity and color perception connected with it.

Most often these are temporary phenomena, but it is advisable to consult a doctor immediately when they appear in order to avoid serious violations. For pregnant women, visual impairment can cause stress, resistance to which is reduced during this period, and if a woman’s activity requires attention and accuracy visual perception– can lead to injury.

If the dosage is not observed, thromboembolism in small vessels may also occur.

This is enough dangerous phenomenon, since it may also affect the arteries of the uterus and placenta, which will cause malnutrition in the fetus. It is almost impossible to recognize such a condition in time by symptoms, so patients need to take blood tests, primarily a coagulogram. This should be done before treatment, several times during it and after completion of the course.

There may also be side effects due to dosage form- nausea, vomiting, dyspepsia when taken orally, pain and phlebitis when administered intravenously.

Everything is currently more women face the threat of early pregnancy termination. There are many reasons that can lead to early loss of a child. This may be due to a changed lifestyle, lack of progesterone, stress, excessive nervous tension, malnutrition, the presence of bad habits and sometimes this problem is related to general condition body of a woman and her individual features.

Any future mom wants to enjoy her pregnancy, to experience joy from her condition, but, unfortunately, everything does not always turn out as rosy as we would like. With the threat of a miscarriage, symptoms such as bloody discharge from the genitals appear, drawing pains lower abdomen. In that case, on scheduled inspection doctor may prescribe drug treatment aimed at maintaining pregnancy. One of the drugs that doctors prescribe is Tranexam.

Tranexam is a drug that has anti-inflammatory and hemostatic effects. The main active ingredient of the drug is tranexamic acid. Therapy with the drug is aimed at stopping bleeding. The drug makes the blood thicker and enhances its clotting. All this contributes to the preservation of pregnancy in the first weeks of its development. In addition, at long-term use there is a pronounced analgesic effect, due to which the agent allows not only to stop bleeding, but also to eliminate pain in the abdomen and lower back. Tranexam during early pregnancy is also prescribed to prevent the threat of miscarriage.

Tranexam: instructions for use during pregnancy

Tranexam is a drug that is available in tablets, in ampoules for injection or in the form of intravenous solution. Moreover, in the latter version, the drug is used for severe bleeding. Sold in pharmacies by prescription only. The course of Tranexam is prescribed by a doctor depending on the diagnosis.

Despite the fact that Tranexam in early pregnancy is considered safe drug, official clinical research on this topic has not been done. The study of the effectiveness of the drug in animals did not reveal negative impact to the fruit.

Tranexam is prescribed at any time during pregnancy, if the doctor finds it appropriate and there are indications. However, most often Tranexam is used in the first trimester of pregnancy. Indications for admission in this case are the threat of miscarriage, spontaneous bleeding. In the second trimester - placental abruption, and in the third - a threat premature birth.

The main indication for the use of Tranexam during pregnancy is the appearance of spotting and bleeding, as well as bruising.

In general, Tranexam is prescribed to pregnant women for the following conditions:

1. Bleeding of a different nature;
2. Placental abruption;
3. The appearance of pain of a pulling nature;
4. Appearance blood secretions from the vagina;
5. Previously diagnosed miscarriages. In this case, the drug can be prescribed from the very beginning of pregnancy as a prophylaxis;
6. Placental abruption;
7. Inflammatory processes;
8. Allergic reactions - urticaria, eczema, angioedema, dermatitis.

The drug may also be prescribed for chronic diseases top respiratory tract. Decreased immunity that occurs during pregnancy exacerbates chronic pathologies Therefore, Tranexam is often included in the combined treatment of diseases such as tonsillitis, tonsillitis, pharyngitis and laryngitis. Also, the use of the drug is quite effective in the treatment of stomatitis and ulcerative lesions of the oral mucosa.

It is important to remember that Tranexam does not have an antiviral and antibacterial effect, therefore it can only be used as aid v complex therapy

How to drink Tranexam during pregnancy

How much can you drink Tranexam during pregnancy? This is very important question, which should be thoroughly studied before taking the drug.

If a woman takes pills, then a single dosage is 250-500 mg. The drug is taken 3-4 times a day for 5-7 days, regardless of food intake at any time of the day. With severe bleeding, the dosage is calculated individually. In the presence of allergies or other diseases that are accompanied by the development of inflammatory processes, the dosage is usually doubled or tripled.

If a pregnant woman is given droppers or injections, then the dosage is usually 10-15 mg / kg. woman's body weight. In some cases, individual adjustment of the method of application may also be required. After the bleeding is stopped, the drug is continued in tablets.

Tranexam: contraindications for use

The only absolute contraindication to the use of Tranexam in pregnant women is subarachnoid bleeding (bleeding into the space between meninges).

Like any medicine, Tranexam has a number of contraindications, in which the use of the drug involves its use with maximum caution. These include:

1. Varicose veins veins;
2. myocardial infarction;
3. Violation of the kidneys, blood in the urinary tract;
4. Poor blood supply to the brain, even if it was observed before conception;
5. Thrombophlebitis of deep veins;
6. Pathology of the fundus;
7. The period of breastfeeding;
8. Individual intolerance to the components.

The drug is usually tolerated by pregnant women calmly, however, in some cases, adverse reactions may occur, which include:

1. Headache, dizziness, loss of consciousness;
2. Nausea, vomiting;
3. allergic reactions;
4. Heartburn;
5. Weakness, drowsiness, fatigue;
6. Decreased visual acuity;
7. Pain in the chest, tachycardia.

If suspicious symptoms appear during the period of taking Tranexam, they should be reported to the attending physician immediately. By observing the dosage of the drug and following the appointments of a specialist, you can reduce the likelihood of developing negative and side effects. If further administration of the drug is not possible, the doctor may prescribe one of the suitable Tranexam analogues as a medicine.

There are the following analogues of Tranexam:

1. Tranexamic acid;
2. Troxaminate;
3. Exacil;
4. Aerus;
5. Cyclocapron.

It is impossible to select an analogue on your own, this should be done only with your doctor.

There are many reasons that can cause uterine bleeding among women. Often used in treatment modern drug Tranexam - effective remedy, allowing you to cope with the opened bleeding or heavy periods in the shortest possible time.

Description of Tranexam

Often used to treat uterine bleeding medicinal product Traneksam. It is used in therapy to reduce and restore the volume of menstruation, to stop bleeding and reduce the risk of miscarriage against the background of bleeding.

The main active ingredient of this drug is tranexamic acid. It is able to influence fibrinolysin - a substance contained in the blood and prevents its coagulation.

An increased content of fibrinolysin provokes intense and prolonged bleeding. This happens when platelets are unable to produce enough plasmin, a component that ensures normal blood clotting. Tranexam is able to convert fibrinolysin to plasmin, thereby helping to stop the increased release of bloody biological fluid.

Pharmacological action of the drug on the human body:

• local and systemic hemostatic (hemostatic);
• anti-inflammatory;
• antihistamine (antiallergic);
• anti-infectious;
• antitumor;
• analgesic (pain reliever).

Forms of release and composition of the drug

The drug has two forms of release: tablets and solution for intravenous administration.

Tableted means is a convex, coated with a water-soluble film, white tablets. Solution - clear liquid, colorless or with a slight light brown tint.

• active substance: tranexamic acid in the amount of 250 or 500 mg;
• auxiliary components:
  • core: cellulose, hyprolose, talc, silicon dioxide, sodium carboxymethyl starch and calcium stearate;
  • shell: titanium dioxide, talc, macrogol, hypromellose.

As part of a solution for injection in an amount of 1 liter:

• tranexamic acid in a volume of 50 g;
• excipient - distilled water up to 1 liter.

Uterine bleeding, in the treatment of which Tranexam helps

Uterine bleeding can be provoked various states or pathologies. They are conditionally divided into 2 categories:

1. Result systematic violations v different bodies or systems.
2. Dysfunctions associated with changes in the functioning of the genital organs.

There are many reasons for such uterine bleeding. Among them:

1. Extragenital (not associated with diseases of the genitourinary system):
   1. Liver diseases such as cirrhosis and liver failure.
   2. Diseases of cardio-vascular system such as atherosclerosis, hypertension.
   3. Infections:
      • flu;
      • measles;
      • sepsis;
      • typhoid fever.
   4. Functional decrease in the work of the thyroid gland.
   5. Blood diseases:
      • hemophilia;
      • hemorrhagic vasculitis;
      • low content of vitamins C and K in the body.
2. Causes associated with pregnancy due to genital diseases:
   1. Pregnancy that occurs with violations in the early stages:
      • uterine;
      • ectopic.
   2. At a later date:
      • scars on the uterus;
      • placental abruption;
      • destruction of cervical tissue;
      • placenta previa.
   3. Generic reasons:
      • rupture of the cervix;
      • delayed separation of the placenta;
      • injury birth canal and genitals;
      • low location of the placenta;
      • afterbirth defects.
   4. Postpartum pathologies:
      • weak uterine tone;
      • delay in the release of the placenta;
      • endometriosis.
3. Genital disorders not related to pregnancy:
   1. bleeding in different age periods associated with pathologies in the functions of the hypothalamus-pituitary-ovaries-adrenals system (depending on the presence or absence of ovulation, this is the so-called dysfunction):
      • juvenile, related to the period of development of the genital organs and maturation (from 10 to 18 years);
        

        If uterine bleeding manifests itself before the age of 9–10 years, then these may be the consequences of the occurrence of a “false” puberty of the child against the background of the development and growth of ovarian tumors.

      • reproductive (puberty);
      • menopausal, directly dependent on menopause (after 45 years).
   2. Tumors on the internal genital organs, including fibroids.
   3. Ruptures of the ovary or cysts on it.
   4. Uterine trauma.
   5. Inflammatory and infectious diseases reproductive organs:
      • cervical erosion;
      • endometritis;
      • vaginitis and vaginosis;
      • cervicitis;
      • endocervicosis.

Such bleeding can be caused by an additional number of factors:

• chronic ailments;
• emotional and mental overexcitation;
• prolonged stress;
• physical overload;
• heredity;
• hypovitaminosis;
• mental trauma;
• endocrine diseases;
• complications after childbirth or abortion.

In addition to the above indications, the basis for the appointment of Tranexam, at the discretion of the attending physician, may be allergic reactions, blood diseases and surgical interventions.

The risk of developing uterine bleeding is assessed by determining the PCT in a blood test:

Uterine bleeding - video

Contraindications

There are a number of contraindications to the use of Tranexam:

• hypersensitivity to the components of the medicinal product;
• subarachnoid hemorrhages (spontaneous outflows of blood into the cavity between the meninges, the result of a rupture or traumatic brain injury);
• thrombosis of various origins:
  • vessels of the brain;
  • myocardial infarction;
  • thrombophlebitis;
• violation of color perception;
• kidney failure;
• hematuria urinary tract (high content erythrocytes in urine);
• thrombohemorrhagic complications.

• penicillins;
• tetracyclines;
• agents for the treatment of hypertension;
• other hemostatics (hemostatic drugs).

Tranexam use during pregnancy and lactation

Tranexam is widely used in gynecology as a remedy that can prevent the threat of miscarriage. Prescribed by a doctor after thorough examination pregnant woman, as in the presence of certain health problems, for example, in the event of a thrombosis, the use this drug forbidden.

During lactation, the medication is taken exclusively for health reasons, since Tranexam carries a potential risk to the child. At the same time, it is recommended to refuse during treatment breastfeeding and transfer the baby to the mixture.

Possible side effects

When using Tranexam tablets, especially if the prescribed dosage is violated, the following side effects may occur:

• nausea and vomiting;
• heartburn;
• unstable stool, diarrhea is possible;
• skin itching;
• rashes on the body;
• weakness of the whole body (lethargy);
• dizziness;
• drowsiness;
• loss of appetite;
• violation of color perception;
• thrombus formation.

Solution for infusion (intravenous and intramuscular injection) can cause the following undesirable effects:

• allergies in the form of:
  • rashes;
  • urticaria;
  • skin itching;
• dyspeptic reactions (violation normal function bodies gastrointestinal tract, difficult and / or painful digestion):
  • anorexia;
  • diarrhea
  • nausea;
• tachycardia;
• pain in the chest area;
• hypotension;
• blurred vision;
• dizziness.

Instructions for use of tablets and solution

Tranexam tablets are taken orally (by mouth) 3-4 times a day. Dosages and duration of treatment are determined by the doctor in accordance with the diagnosed disease. Usually the duration of the course is no more than two weeks. Therapy is carried out under the supervision of medical staff, independent use forbidden.

The solution for infusion is administered drip or jet. The dose calculation is made by a specialist. Sometimes a single application is enough. The maximum duration of treatment is three days.

Traneksam's analogs

There are structural and pharmacological analogues of this drug. Those drugs that basically have the same active ingredient have similar effects and contraindications to Tranexam:

• Exacil;
• Troxaminate;
• Traxara;
• Cyclocapron.

What can replace the drug - table

Termination of pregnancy (detachment of the ovum) is the most serious pathology that can occur during the bearing of a baby. Most often this happens in the early stages, when a woman’s body produces an insufficient amount progesterone.

Doctors believe that the main causes of this pathology are excessive nervous tension, chronic stress, malnutrition, alcohol consumption and smoking.

Most dangerous period in terms of maintaining pregnancy, a period of 4 to 8-12 weeks is considered. The first sign of a detachment that has begun is spotting, which can be insignificant (just a few drops) and quite plentiful, turning into uterine bleeding. To stop it, a woman is prescribed hemostatic drugs, one of which is Tranexam.

The main active ingredient is tranexamic acid. It has anti-inflammatory and hemostatic properties. With prolonged use, a moderate analgesic effect is observed, so the remedy helps not only to stop bleeding, but also to eliminate pulling pains in the lower abdomen and lower back.

This property of tranexamic acid allows the use of "Tranexam" for painful and heavy menstruation(menorrhagia) and for the prevention of heavy postpartum bleeding.

The drug is available in three dosage forms:

• white tablets in film sheath convex shape (250 mg and 500 mg);
• intravenous solution (50 g of tranexamic acid in 1 liter of the drug);
• injection.

With severe bleeding, "Tranexam" is used in the form of a solution. After stopping the attack, the woman is prescribed a further intake of Tranexam in the form of tablets to maintain the therapeutic effect and prevent new bleeding.

Important! The active substance of the drug exhibits moderate anti-allergic properties, so "Tranexam" can be included in combination therapy in women prone to allergies.

Can it be taken during pregnancy?

Tranexam is considered a safe drug to use during pregnancy, but no official studies have been conducted on this topic. Animal testing did not reveal negative impact on the fetus, but it was found that the active substance is able to penetrate the placental barrier and accumulate in the tissues and organs of the fetus.

Most often, the remedy is prescribed to expectant mothers in the first trimester, since it is during this period that the risk of spontaneous interruption is highest. To avoid negative consequences, it is important to adhere to the following recommendations of experts:

• do not use "Tranexam" without a prescription from the attending physician, since there is no reliable data on the effect of the components of the drug on the course of pregnancy and fetal development;
• before use, consult an ophthalmologist (women with impaired color perception and fundus pathologies are not recommended to use the medicine);
• if side effects occur or if you feel unwell during treatment, report this to the gynecologist in charge of the pregnancy or the specialist who made the appointments.

Important! Despite the lack of data on the safety of use during pregnancy, doctors prescribe Traneksam, considering it one of the most effective and efficient drugs.

Many years of experience of use confirms good tolerance and the absence of embryotoxic effects, therefore, in most cases, the drug becomes the drug of choice in case of a threatened miscarriage.

Tranexam for bleeding and other diseases

The main indication for the use of Tranexam during childbearing is the appearance of spotting and bleeding, hematomas. Severe bleeding is dangerous not only for the fetus, but also for the life of a woman, therefore, in such cases, higher doses of tranexamic acid are prescribed, which are administered using a dropper.

The drug can also be prescribed for chronic diseases of the upper respiratory tract and oropharynx. The decrease in immunity that occurs during pregnancy can exacerbate chronic pathologies, so Traneksam is often included in the combined treatment of the following diseases:

• angina;
• tonsillitis;
• pharyngitis;
• laryngitis.

Effective use of the drug for stomatitis and ulcerative lesions oral mucosa. The tool stops the inflammatory process and provides an analgesic effect, eliminating discomfort when eating.

"Tranexam" does not have antibacterial, antiviral or antifungal activity, therefore, it can only be used as an adjuvant that does not replace the main treatment.

Another indication for the use of the drug during pregnancy is hereditary allergic reactions and diseases, for example:

• hives;
• rash of toxic origin;
• dermatitis;
• eczema;
• angioedema.

Sometimes "Tranexam" is prescribed to prevent allergies when using potent drugs (if there is a need for their use).

Instructions for use and doses: how much to drink

"Tranexam" is safe for expectant mothers, but only if the instructions are followed, therefore, before use, you must familiarize yourself with the regimen of administration and dosing.

Tablets

Tablets are taken orally at any time of the day, regardless of food intake. In case of bleeding, the dosage is calculated individually, taking into account the severity of the pathology and the severity of the main symptoms. The default schema looks like this:

• single dosage - 250-500 mg;
• the number of applications per day - 3-4 times;
• duration of treatment - 7 days.

With allergies and other diseases accompanied by inflammatory processes, the dosage is increased to 1000-1500 mg. The drug should be drunk 2-3 times a day. The duration of treatment depends on the severity of the symptoms and can range from 3 to 9 days.

Droppers and injections

A solution for drip administration is prescribed for heavy bleeding that cannot be stopped with oral forms of the drug. The dosage is usually from 10 to 15 mg per kilogram of a woman's weight, but in some cases, individual correction of the application regimen may be required.

The drug is infused by drip or jet method at a rate of 1 ml / min every 6-8 hours until the bleeding stops completely. After stopping the attack, the patient is prescribed a further intake of "Tranexam" in the form of tablets.

Contraindications and side effects

The only absolute contraindication to the use of "Tranexam" in expectant mothers is subarachnoid bleeding (bleeding into the space between the meninges). Restriction for admission is also intolerance and hypersensitivity to the components of the drug.

As relative contraindications the instruction states:

• myocardial infarction;
• the formation of blood clots in the vessels of the brain;
• impaired visual acuity or pathology of the fundus;
• blood in the urinary tract;
• insufficiency of functioning of kidneys;
• thrombosis with inflammation venous walls(thrombophlebitis).

With these diseases, Tranexam should be taken with extreme caution and under the constant supervision of a doctor. Usually a woman is placed in a maternity hospital for preservation.

The drug is usually well tolerated, but in some cases, adverse reactions may occur, which include:

• headache;
• vomiting and nausea;
• decreased visual acuity;
• allergies (urticaria, eczema) - mainly when using the drug in the form of a solution;
• heartburn;
• weakness and drowsiness;
• dizziness (in rare cases- loss of consciousness);
• pain behind the sternum and in the chest area;
• tachycardia.

Important! The use of Tranexam increases the likelihood of thrombosis and thromboembolism, but doctors believe that the risk of developing these pathologies is minimal. This information is confirmed by the official instructions.

What to replace: safe analogues

Replacement of "Tranexam" medical indications very rarely required, since the drug is well tolerated and does not cause negative consequences for the course of pregnancy and fetal development.

If necessary, the agent can be replaced by drugs with a similar composition or similar pharmacological action. Analogues of "Tranexam", allowed for pregnant women, include:

• "Tranexamic acid";
• "Exacil";
• "Aerus";
• "Troxaminate";
• "Ingitril".

It is necessary to select an analogue together with the attending physician, since even with the same active substance various adverse reactions may occur, which the doctor takes into account when prescribing treatment for a particular patient.

"Tranexam" - effective drug, which at correct application rarely causes side effects and complications. It can be used during pregnancy only as prescribed by a doctor and after examination by an ophthalmologist, as visual impairment and a violation of the perception of colors are possible.