Photo of the drug

Latin name: Iodomarin

ATX code: H03CA

Active ingredient: Potassium iodide (Potassium iodide)

Manufacturer: Berlin-Chemie AG (Menarini group), Germany

Manufacturer's website: berlin-chemie.ru

Description is valid on: 16.10.17

Iodomarin is a medicinal and prophylactic agents, which are used in case of thyroid diseases.

The composition of the drug includes important component– calcium iodide. This element is difficult to find in nature in pure form, its concentration in products is not sufficient to prevent the development of many ailments. That's why this medication is an irreplaceable source of iodine - an important microelement for any organism.

On this page you will find all the information about Iodomarin: full instructions as applied to this medicine, average prices in pharmacies, complete and incomplete analogues of the drug, as well as reviews of people who have already used Iodomarin. Would you like to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Iodine preparation for the prevention and treatment of thyroid diseases.

Conditions for dispensing from pharmacies

Available without a prescription.

Prices

How much does Yodomarin cost? Average price in pharmacies it is at the level of 140-240 rubles.

Release form and composition

Dosage form of Iodomarin - tablets: almost white or white, round flat-cylindrical shape, chamfered, with slightly beveled edges and a dividing line on one side (50 or 100 pieces in a dark glass bottle, 1 bottle in a cardboard pack).

• Iodomarin contains 100 or 200 mcg of iodine in the form of potassium iodide (Potassium iodide), as well as auxiliary components: lactose in the form of monohydrate (Lactose monohydrate), magnesium carbonate (Magnesium carbonate) main, gelatin (Gelatine), sodium carboxymethyl starch (Sodium carboxymethyl starch), colloidal silicon dioxide (Silicium dioxide colloidal), magnesium stearate (Magnesium stearate).

Currently, Iodomarin is available in Russia in two varieties, called Iodomarin 100 and Iodomarin 200. These varieties differ from each other only in the number in the name and dosage active component. There are no other differences between Iodomarin 100 and Iodomarin 200, therefore, in essence, these varieties are just the same drug with different dosages active substance and different names.

Pharmacological effect

Iodine preparation. Used for the prevention and treatment of thyroid diseases. The trace element iodine belongs to essential microelements necessary for implementation normal operation thyroid gland. Iodine is not synthesized in the body, therefore, all the required amount must enter the body from the outside.

When the optimal amount of iodine is supplied, the development of various diseases thyroid gland, including endemic goiter. Iodomarin replenishes the lack of iodine received by the body from food, which is especially important in endemic areas, i.e. in those areas where in the soil, etc. the amount of iodine is not enough.

Indications for use

Considered medicinal product should be taken only when prescribed by a doctor. And the indications for the use of Iodomarin are:

• therapy for diffuse euthyroid goiter;
• therapy and prevention of iodine deficiency in childhood;
• treatment of conditions associated with iodine deficiency in the body;
• prevention of endemic goiters (carried out among patients living in regions with severe iodine deficiency).

In addition, doctors prescribe Yodomarin in postoperative period, or after finishing therapeutic treatment for endemic goiter and as a prevention of iodine deficiency in elderly people.

Contraindications

According to the instructions, Iodomarin should not be prescribed for:

1. Dühring's dermatitis herpetiformis;
2. Hemorrhagic diathesis;
3. Having hypersensitivity to iodine or any of the auxiliary components medicine;
4. Toxic adenoma and others benign tumors thyroid gland;
5. Expressed or hidden hyperfunction of the thyroid gland, including diffuse and nodular toxic goiter;
6. Latent hyperthyroidism (at a dose exceeding 150 mcg per day);
7. Lactase deficiency congenital intolerance galactose, glucose-galactose malabsorption syndrome (since Iodomarin contains lactose).

Cannot exceed daily dosage 300 mcg for autonomous adenoma, diffuse and focal foci of the thyroid gland, the only exception is preoperative iodine therapy for the purpose of blocking the thyroid gland according to Plumer.

Use during pregnancy and lactation

During pregnancy and lactation, the need for iodine increases, so it is especially important to use it in sufficient doses (200 mcg/day) to ensure adequate iodine intake in the body. The drug crosses the placenta and is excreted from breast milk Therefore, the use of the drug during pregnancy and lactation is possible only in recommended doses.

Instructions for use

The instructions for use indicate that Iodomarin tablets should be taken after meals, washed down with a sufficient amount of non-carbonated clean water(at least half a glass). The tablets can be broken and divided into halves according to the score on one side to obtain the required dosage. It is advisable to swallow the tablet whole, but if for some reason this is impossible, then it is better not to chew it, but to dissolve it in milk or juice, and then drink the resulting ready-made solution of the drug.

Dissolving the tablet is recommended as the optimal route of administration for young children. The tablet dissolves easily in liquids, so in order to give the drug to an infant or an adult, it can be mixed into any drink (water, juice, milk, etc.) or liquid food (soup, puree, broth, milk, formula) etc.).

• Prevention of goiter: newborns and children up to 12 years old - 50-100 mcg of iodine or ½-1 piece, patients over 12 years old - 100-200 mcg or 1-2 pieces, during pregnancy and lactation - 200 mcg or 2 pcs.;
• Prevention of goiter relapse: 100–200 mcg or 1–2 pcs.;
• Treatment of euthyroid goiter: newborns and children under 18 years old - 100-200 mcg or 1-2 pcs., adults up to 40 years old - 300-500 mcg or 3-5 pcs.

Taking pills with for preventive purposes can last for several years, for the purpose of treatment – ​​for life.

On average, 2–4 weeks are enough for newborns to treat goiter; for children and adults – 0.5–1 year or a longer period.

Side effects

At prophylactic use at any age, as well as in the treatment of euthyroid goiter in newborns, children and adolescents, as a rule, no side effects are observed.

In rare cases, continuous use of the drug can lead to the development of “iodism”, which can manifest itself metallic taste in the mouth, swelling and inflammation of the mucous membranes (runny nose, conjunctivitis, bronchitis), “iodine fever”, “iodine acne”. It is extremely rare to develop Quincke's edema and exfoliative dermatitis.

Overdose

Long-term use of the drug in dosages exceeding 150 mcg/day can provoke latent hyperthyroidism to become manifest, and constant use of Iodomarin in a dose exceeding 300 mcg/day can cause the development of iodine-induced thyrotoxicosis.

In case of an overdose of the drug, the following appear: clinical symptoms:

1. Diarrhea, abdominal pain.
2. Reflex vomiting.
3. Brown coloration of the mucous membrane.

It is extremely rare that esophageal stenosis, dehydration and shock may develop. If such symptoms appear, it is necessary to rinse the stomach with a solution of starch, sodium thiosulfate or protein. Symptomatic therapy is prescribed to restore the electrolyte and water balance of the body.

Special instructions

Before starting to take Iodomarin tablets, it is important to carefully read the instructions for the drug. There are several special instructions, which you should pay attention to include:

1. The drug does not affect the ability to concentrate attention and the speed of psychomotor reactions.
2. According to indications, the drug can be used for children, pregnant and lactating women.

Drug interactions

1. High doses of the drug in combination with potassium-sparing diuretics can lead to hyperkalemia.
2. Simultaneous treatment with high doses of iodine and lithium salts can contribute to the occurrence of goiter and hypothyroidism.
3. Iodine deficiency increases, and iodine excess decreases, the effectiveness of hyperthyroidism treatment with thyreostatic drugs (before or during the treatment of hyperthyroidism, it is recommended, if possible, to avoid any use of iodine). On the other hand, thyreostatic agents inhibit the conversion of iodine into an organic compound in the thyroid gland and thus can cause goiter formation.

Name:

Name: Iodomarin

Indications for use:
- prevention of thyroid diseases caused by insufficient intake of iodine into the body, also for the prevention of iodine deficiency in people who need increased iodine intake (pregnant women, breastfeeding mothers, adolescents, children);
- as a prevention of goiter recurrence after surgery on the thyroid gland or after the end of drug treatment for goiter;
- treatment of a number of diseases caused by insufficient iodine intake: diffuse non-toxic goiter, diffuse euthyroid goiter.

Pharmacological action:
Iodine preparation. Used for the prevention and treatment of thyroid diseases. The trace element iodine is an essential trace element necessary for the normal functioning of the thyroid gland. Iodine is not synthesized in the body, therefore, all the required amount must enter the body from the outside. When receiving the optimal amount of iodine, the development of various thyroid diseases, including endemic goiter, is prevented. Iodomarin replenishes the lack of iodine received by the body from food, which is especially important in endemic areas, i.e. in those areas where in the soil, etc. the amount of iodine is not enough.

Iodomarin method of application and dosage:
To prevent goiter, the following is prescribed:
- children (including infancy and newborns) - 50-100 mcg/day;
- adolescents and adults - 100-200 mcg/day;
- pregnant women and during breastfeeding- 200 mcg/day.
To prevent goiter recurrence, it is prescribed daily dose iodomarin - 100-200 mcg.

Any preventive intake of iodine products is usually carried out for a long time over several years, continuously or in courses. Sometimes iodine deficiency is prevented for life.

For the treatment of goiter the following is prescribed:
- children and adolescents 100-200 mcg/day;
- adults up to 45 years old at a dose of 300-500 mcg/day.
Children (including newborns) should take Iodomarin for about 2-4 weeks. For teenagers, adults and children school age- 6-12 months.
The tablets are taken after meals with a sufficient amount of liquid.

Iodomarin contraindications:
- hyperthyroidism;
- toxic adenoma of the thyroid gland, with the exception of the period of preoperative iodine therapy;
- intolerance to iodine products;
- dermatitis herpetiformis Dühring.

Iodomarin side effects:
From the outside endocrine system:
- when using the product in a dose of up to 150 mcg/day, it is possible for latent hyperkeratosis to transform into a manifest form (i.e., a form that occurs with all the main clinical signs diseases);
- when using the product at a dose of more than 300-1000 mcg/day, iodine-induced iodine may develop, i.e. resulting from excess iodine intake, hyperkeratosis. The likelihood of its occurrence is higher in people who take Iodomarin for a long time, as well as in elderly people and those suffering from nodular or diffuse toxic goiter.

Allergic reactions: manifest themselves in the form of iodism. Main clinical symptoms: metallic taste in the mouth, swelling, inflammation of the mucous membranes, so-called iodine “rhinitis”, “conjunctivitis”, glossitis, “iodine” acne, “iodine” fever. Typical symptoms do not often develop allergic reactions in the form of Quincke's edema, also exfoliative dermatitis.

Pregnancy:
The product can be used during pregnancy and breastfeeding.

Overdose:
the possible effects of an overdose are identical to the side effects when taking the product.

Use with other medications:
When using the product simultaneously with potassium-sparing diuretics, hyperkalemia may develop.
When taking Iodomarin simultaneously with lithium products, goiter may progress.

Yodomarin 200 contains:

1 tablet contains:

Active ingredients: potassium iodide 262 mcg, which corresponds to an iodine content of 200 mg.

Excipients: lactose monohydrate - 150.238 mg, basic magnesium carbonate - 56.5 mg, gelatin - 8 mg, sodium carboxymethyl starch (type A) - 9.5 mg, colloidal silicon dioxide - 3.5 mg, magnesium stearate - 2 mg.

Pharmacological action

Pharmacodynamics

Iodine preparation for the treatment and prevention of thyroid diseases. Iodine is vital important trace element necessary for normal functioning of the thyroid gland. Thyroid hormones perform many vital functions important functions, incl. regulate the metabolism of proteins, fats, carbohydrates and energy in the body, the activity of the brain, nervous and cardiovascular systems, reproductive and mammary glands, as well as the growth and development of the child.

The use of the drug Yodomarin® replenishes iodine deficiency in the body, preventing the development of iodine deficiency diseases, helps normalize the function of the thyroid gland, which is especially important for children and adolescents, as well as during pregnancy and lactation.

Pharmacokinetics

Data on the pharmacokinetics of the drug Yodomarin® are not provided.

What does Yodomarin 200 help with: indications

Not described.

Contraindications

• Hypersensitivity to iodine
• hyperthyroidism
• toxic adenoma of the thyroid gland, nodular goiter when used in doses of more than 300 mcg/day (except for the period of preoperative iodine therapy to block thyroid function)
• Dühring's herpetiformis (senile) dermatitis.

The drug should not be used for hypothyroidism, except in cases where the development of the latter is caused by severe iodine deficiency.

Prescription of the drug should be avoided during therapy with radioactive iodine, the presence or suspicion of thyroid cancer.

Iodomarin 200 during pregnancy and breastfeeding

During pregnancy and lactation, the need for iodine increases, so it is especially important to use the drug Yodomarin® in sufficient doses (200 mcg/day) to ensure adequate intake of iodine into the body.

The use of the drug Yodomarin® during pregnancy and lactation (breastfeeding) is possible only in recommended doses, because active substance penetrates the placenta and is excreted in breast milk.

Iodomarin 200: instructions for use

Prevention of endemic goiter

• Newborns and children under 12 years of age: 1/2-1 tab. drug Yodomarin® 100 or 1/2 tablet. the drug Yodomarin® 200 per day (which corresponds to 50-100 mcg of iodine).
• Children over 12 years old and adults: 1-2 tablets. drug Yodomarin® 100 or 1/2-1 tablet. the drug Yodomarin® 200 per day (which corresponds to 100-200 mcg of iodine).
• During pregnancy and lactation: 2 tablets. Iodomarin® 100 or 1 tablet. the drug Yodomarin® 200 per day (which corresponds to 200 mcg of iodine).

Prevention of goiter recurrence

1-2 tab. drug Yodomarin® 100 or 1/2-1 tablet. the drug Yodomarin® 200 per day (which corresponds to 100-200 mcg of iodine).

Treatment of euthyroid goiter

• Newborns and children aged 1 to 18 years: 1-2 tablets. drug Yodomarin® 100 or 1/2-1 tablet. the drug Yodomarin® 200 per day (which corresponds to 100-200 mcg of iodine).
• Adults up to 40 years old: 3-5 tablets. Iodomarin® 100 per day or 11/2-21/2 tablets. the drug Yodomarin® 200 per day (which corresponds to 300-500 mcg of iodine).

The drug is taken after meals with a sufficient amount of liquid. When used in children, it is recommended to first dissolve the drug in milk or juice.

Prophylactic administration is carried out for several years, if indicated - for life.

For the treatment of goiter in newborns, on average, 2-4 weeks are sufficient; in children, adolescents and adults, 6-12 months are usually required; long-term use is possible.

The duration of treatment is determined by the attending physician.

Side effects

With the prophylactic use of the drug Iodomarin® in patients of any age side effects, as a rule, is not observed.

From the endocrine system: when using the drug in a dose of more than 150 mcg of iodine/day, latent hyperthyroidism can become manifest when using the drug in a dose exceeding 300 mcg of iodine/day, iodine-induced thyrotoxicosis may develop (especially in elderly patients suffering from goiter for a long time, if present nodular goiter or diffuse toxic goiter).

Allergic reactions: rarely - iodine, manifested by a metallic taste in the mouth, swelling and inflammation of the mucous membranes ("iodine" rhinitis, conjunctivitis, bronchitis), "iodine" fever, "iodine" acne in some cases - Quincke's edema, exfoliative dermatitis.

Special instructions

Impact on the ability to drive vehicles and other mechanisms that require increased concentration attention

Iodomarin® does not affect the ability to drive vehicles or perform other potentially hazardous activities.

Compatibility with other drugs

Iodine deficiency increases, and iodine excess decreases, the effectiveness of hyperthyroidism treatment with thyreostatic drugs (before or during the treatment of hyperthyroidism, it is recommended, if possible, to avoid any use of iodine). On the other hand, thyreostatic agents inhibit the conversion of iodine into an organic compound in the thyroid gland and thus can cause goiter formation.

Simultaneous treatment with high doses of iodine and lithium salts can contribute to the occurrence of goiter and hypothyroidism.

High doses of the drug in combination with potassium-sparing diuretics can lead to hyperkalemia.

Overdose

Symptoms: brown staining of the mucous membranes, reflex vomiting (if starch-containing components are present in food, the vomit becomes blue), abdominal pain and diarrhea (possibly melena). In severe cases, dehydration and shock may develop. In rare cases, esophageal stenosis and the phenomenon of “iodism” were observed.

Treatment: with acute intoxication- discontinuation of the drug, gastric lavage with a solution of starch, protein or 5% sodium thiosulfate solution until all traces of iodine are removed with chronic intoxication- drug withdrawal. Symptomatic therapy for water and electrolyte imbalances, anti-shock therapy.

When treating iodine-induced hypothyroidism - discontinuation of the drug, normalization of metabolism with the help of thyroid hormones.

In the treatment of iodine-induced thyrotoxicosis - no treatment is required for mild forms; severe forms thyreostatic therapy is required (the effect of which is always delayed). In severe cases (thyrotoxic crisis), it is necessary to intensive care, plasmapheresis or thyroidectomy.

Storage conditions and shelf life

Store out of reach of children, in a dry, dark place at a temperature not exceeding 25°C.

Analogues and prices

Among foreign and Russian analogues Iodomarin 200 is released:

Microiodide. Manufacturer: Tatkhimpharmpreparaty (Russia). Price in pharmacies from 73 rubles.
Iodine balance. Manufacturer: Merck KGaA (Germany). Price in pharmacies from 116 rubles.
Iodomarin 100. Manufacturer: Berlin-Chemie/Menarini (Germany). Price in pharmacies from 132 rubles.