Aminocaproic acid for the treatment of children's rhinitis. Non-standard use of aminocaproic acid in childhood

Protect your children from colds very difficult, because their immunity is just beginning to form, so it is often not able to cope with infectious agents. Many parents try to replace medical preparations folk remedies, but this does not always work. In some cases, it is better to use safe drugs traditional means than to start a disease using prescriptions traditional medicine. Aminocaproic acid in the nose is popular with experienced parents, the use of which allows you to eliminate the symptoms of the disease immediately after they appear.

Composition and action of the drug

Aminocaproic acid is a hemostatic drug that has the ability to convert profibrinolysin to fibrinolysin. The drug is available in the following pharmacological forms:

powder for injection;
granules - aminocaproic acid is prescribed in this form to children;
5% solution.

The drug can be used intravenously, orally and externally. Quite common is the use of aminocaproic acid in the nose for infectious diseases.

The instructions indicate that aminocaproic acid is an inhibitor of fibrinolysis. The drug has a hemostatic effect in various bleeding caused by an increase in fibrinolysis in the body. This remedy has an anti-allergic effect, in addition, it enhances liver function, resulting in increased destruction of toxins, and capillary permeability also decreases. The maximum concentration of the substance in the blood is observed after three hours after its application.

The advantage of the drug is its low toxicity and rapid excretion from the body, 4 hours after intravenous administration drugs 40-60% is excreted in the urine. However, if a person's kidney function is impaired, the drug is delayed in the body and soon its concentration in the blood increases significantly.

The use of the drug for colds

Aminocaproic acid, having an antiviral effect on the body, is used in the treatment of influenza, adenoviruses, colds and SARS. The drug destroys pathogenic bacteria in the human body, and also prevents further penetration of the virus through the respiratory tract. Instillation of aminocaproic acid into the nose is based on its anti-edematous and anti-allergic effect. By instilling or irrigating the nasal cavity with a remedy, the amount of pathological secretion is reduced, the inflammatory process is removed, and the interaction of the body with the virus is disrupted.

It is advisable to instill aminocaproic acid into the nose not only with the development of a cold, but also as a prophylaxis during a viral infectious epidemic. Children need to drip their nose 4-5 times a day for a week. If observed acute course diseases, the drug can be administered intravenously, orally or in the form of inhalations. At acute form colds or rhinitis, you need to drip into each nasal passage 3 drops every three hours until the signs of the disease completely disappear.

Good results are obtained in the treatment of colds with aminocaproic acid in combination with other antiviral and immunomodulatory drugs. During pregnancy, the treatment of a cold with aminocaproic acid does not have categorical contraindications, but it can only be used as directed by a specialist.

Treatment of adenoids

The drug allows you to actively fight adenoviruses, in addition, when instilled into the nose, you can get rid of adenoids of the first degree. Nasal instillation must be alternated with inhalation of the child with aminocaproic acid. For inhalation, the agent is used in the form of a 5% solution. One procedure requires the use of 2 ml of the drug. Inhalations should be carried out twice a day for four days.

The drug is effective not only in the treatment of a runny nose caused by an infection or adenoids, some experts prescribe aminocaproic acid for cough inhalation.

Contraindications and side effects

Aminocaproic acid with a cold is not prescribed for all patients, because it has its own contraindications. Among them are.

Aminocaproic acid is widely used in surgery as a hemostatic agent and in blood transfusion. However, it has a fairly wide spectrum of action and can be used for colds, flu and SARS. But prescribe aminocaproic acid to children for these purposes in last years rare, associated with the appearance a large number drugs of similar action.

Aminocaproic acid - release form

The drug is available in the form of a powder, granules for children and a 5% solution for infusion.

Aminocaproic acid in the nose for children with a cold

The substance has an anti-allergic effect, relieves swelling of the mucous membrane and nasal sinuses, which is different from most vasoconstrictor drugs used for a cold, but at the same time significantly reduces the amount of discharge during a cold. In addition, aminocaproic acid strengthens the walls of blood vessels, increases the level of blood clotting and prevents the occurrence of nosebleeds. Apply a few drops into each nasal passage with an interval of three hours.

Aminocaproic acid in ARVI

Possessing an antiviral effect, the drug is successfully used for the treatment and prevention of influenza, adenoviruses and various acute respiratory viral infections. It prevents the reproduction and penetration of pathogens into the body through the upper respiratory tract. For prevention in the season of colds, aminocaproic acid is instilled into the nose of children 4-5 times a day. The duration of the prophylactic course averages from 3 to 7 days.

In the acute course of the disease, it is possible to prescribe the drug by mouth, inhalation with a solution of aminocaproic acid, as well as a combination of its use with other antiviral and immunomodulatory drugs.

Aminocaproic acid for adenoids

The drug is also successfully used to combat adenoviruses and even cures first-degree adenoids that have already arisen. For this, rinsing with a solution for infusions and also regular instillations are prescribed.

Contraindications

Aminocaproic acid is relatively safe, it is prescribed for children, as well as women during pregnancy and lactation. But, like any other drug, it has a number of contraindications:

disorders of cerebral circulation;
kidney failure;
individual intolerance to the drug.

Before using aminocaproic acid, you should consult your doctor.

Aminocaproic acid for a cold: reviews for colds and rhinitis

Colds are a real misfortune in the cool days of the off-season and the dank-wet weather of the autumn-winter period.

These days, children get sick most often and most quickly, since they have not yet established immunity. It cannot cope with all the infections and viruses that attack them every day.

Unpleasant initial symptoms colds are not always eliminated by folk remedies, often, the disease clings to the body more and more, developing a cough and runny nose, raising the temperature.

Weak the immune system weakened even more and is no longer able to somehow fight the infection.

Many parents use aminocaproic acid in the form of nose drops when the first signs of a runny nose appear in children. And it is considered one of the most effective ways fight pathogens that enter the body.

Composition and action of the drug

Aminocaproic acid copes well with the infection, not only killing pathogens that have already entered the body, but also preventing their further entry from the outside.

This is a hemostatic drug, which, like other drugs, does not tolerate rash use. It comes in several types and is available in pharmacies in the form of an injectable powder, a five percent solution and granules.

This medicine is used in three ways:

Intravenously;
Orally;
Outwardly.

Unlike many drugs, aminocaproic acid has low toxicity and is excreted from the body four hours after administration. This occurs mainly through urination, so people with any kidney problems may have complications with the elimination of toxins.

The drug will stay in the body, and its concentration will increase.

Aminocaproic acid has a whole bunch of useful properties:

Stops blood during various bleeding, as it promotes blood clotting;
Possesses anti-allergic action;
Improves liver function, enhancing its functions and allowing you to quickly deal with toxins;
Reduces capillary permeability.

The use of the drug for colds

Due to its antiviral effect, the amino acid copes with diseases such as influenza, colds, SARS. It kills pathogenic bodies in the body and does not allow them to penetrate through respiratory system.

In addition, the drug relieves inflammation and swelling, which often occurs with a runny nose. If there are any allergic reactions, it helps to cope with that too.

During a runny nose, aminocaproic acid is instilled into the nose, because it is through the respiratory system that infection and viruses enter the body. For the same reason, it is useful to instill it during flu outbreaks or seasonal colds, as a preventive measure. For this, the nose is instilled three or four times a day. Treatment continues for a week.

If the disease has already gained momentum and complications have begun, it is advisable to do intravenous injection. In addition, the drug can be administered orally and by inhalation.

Aminocaproic acid works well on its own for a runny nose, but it's best to use it along with other medications and cold remedies during a cold. Comprehensive treatment will bring faster and more reliable results.

This medicine can be used successfully in pregnant women and very young children. Of course, before that, it is important to approve it with your doctor and check for contraindications and intolerances.

Aminocaproic acid can be used for the following diseases:

Colds: flu, bronchitis, etc. Acting directly on viruses and bacteria, it eliminates those already in the body and prevents new ones from getting there;
Runny nose, as a cold symptom and as a separate disease;
Adenoids of the first degree. For treatment, it is necessary to alternate instillations and inhalations, doing these procedures several times a day for a week.

Contraindications and side effects

In spite of wide range action, aminocaproic acid is not always prescribed to the patient. As mentioned above, it has its own characteristics, which are important to know so as not to harm yourself:

Any kidney problems, especially kidney failure. This will make it more difficult for the drug to leave the body, as it is excreted in the urine and kidney problems can trap the acid in the body.
Impaired circulation;
macrohematuria;
Embolism;
Thrombosis;
Thrombofolia;
Sensitivity to the components of the drug, intolerance to it.

In addition, aminocaproic acid has its own side effects, and its overdose can end badly. It is important to strictly follow the instructions for use and do not forget about the instructions of the doctor. Otherwise, you will have to cope not only with the symptoms of the disease, but also with very unpleasant side effects:

nausea and diarrhea;
Headache and dizziness;
convulsions;
Arrhythmia;
Noise in ears;
Rash;
Inflammation of the mucous membranes respiratory tract.

With a severe overdose, almost all symptoms of side effects may appear, and in this case, urgent hospitalization and rehabilitation of the affected organism is needed. Proper application will never cause such reactions.

And the video in this article will tell you in detail about why a runny nose must be treated in a timely manner.

Aminocaproic acid: properties and use of the drug

It is very difficult to protect your children from colds, because their immunity is just beginning to form, so it is often not able to cope with infectious agents. Many parents try to replace medications with folk remedies, but this does not always work out. In some cases, it is better to use safe traditional medicines than to start the disease using traditional medicine recipes. Aminocaproic acid in the nose is popular with experienced parents, the use of which allows you to eliminate the symptoms of the disease immediately after they appear.

Composition and action of the drug

Aminocaproic acid is a hemostatic drug that has the ability to convert profibrinolysin to fibrinolysin. The drug is available in the following pharmacological forms:

powder for injection;
granules - aminocaproic acid is prescribed in this form to children;
5% solution.

The drug can be used intravenously, orally and externally. Quite common is the use of aminocaproic acid in the nose for infectious diseases.

The advantage of the drug is its low toxicity and rapid excretion from the body; 4 hours after intravenous administration of the drug, 40–60% is excreted with urine. However, if a person's kidney function is impaired, the drug is delayed in the body and soon its concentration in the blood increases significantly.

The use of the drug for colds

It is advisable to instill aminocaproic acid into the nose not only with the development of a cold, but also as a prophylaxis during a viral infectious epidemic. Children need to drip their nose 4-5 times a day for a week. If there is an acute course of the disease, the drug can be administered intravenously, orally or in the form of inhalations. In the acute form of a cold or rhinitis, you need to drip 3 drops into each nasal passage every three hours until the signs of the disease completely disappear.

Treatment of adenoids

The drug is effective not only in the treatment of a runny nose caused by an infection or adenoids, some experts prescribe aminocaproic acid for cough inhalation.

Contraindications and side effects

Aminocaproic acid with a cold is not prescribed for all patients, because it has its own contraindications. These include:

kidney failure;
impaired circulation;
hypersensitivity to the components of the drug or their intolerance;
macrohematuria;
thrombophilia;
embolism;
thrombosis.

Rarely may occur side effects, which are the result of an overdose or the use of the drug if the patient has contraindications to it. Side effects can manifest as arrhythmia or bradycardia, orthostatic hypotension, subendocardial hemorrhage, nausea and diarrhea, headache, convulsions and dizziness. Patients may also complain of a sensation of tinnitus, allergic manifestations in the form of a rash. Specialists sometimes detect inflammation of the mucous membranes of the upper respiratory tract.

At correct application aminocaproic acid it is absolutely safe drug without causing any side effects.

Aminocaproic acid is a hemostatic drug that inhibits the conversion of profibrinolysin to fibrinolysin.

Released:

Powder for solution for intravenous use;
Granules (Aminocaproic acid for children);
5% solution of the agent in isotonic sodium chloride solution.

The drug is used orally, intravenously and externally. Aminocaproic acid is often used in the nose for the treatment and prevention of diseases of infectious origin.

pharmachologic effect

According to the instructions, Aminocaproic acid is an inhibitor of fibrinolysis. The drug produces a specific hemostatic effect in various bleedings, which are caused by an increase in fibrinolysis. This process is associated with the blockade of plasminogen activators and partly with inhibition of the influence of plasmin. The drug inhibits kinins - biogenic polypeptides that are formed in the body from α-globulins under the influence of kallikrein.

Aminocaproic acid is an anti-allergic agent. In addition, the drug enhances the function of the liver, aimed at the destruction of toxins, and reduces the permeability of capillaries.

This drug has a low toxicity. 15-20 minutes after intravenous administration, the action of drugs begins. Excretion of aminocaproic acid occurs through the kidneys - approximately 40-60 percent is excreted in the urine as early as 4 hours after ingestion. If the excretory function of the kidneys is impaired, then the substances of the drug are retained in the body and their concentration in the blood increases sharply.

Indications for use

The use of Aminocaproic acid is indicated for the following conditions and diseases:

Bleeding (afibrinogenemia, hypofibrinogenemia, hyperfibrinolysis), bleeding due to surgical operations and pathological conditions, which are accompanied by an increase in fibrinolytic activity of the blood (with intracavitary, neurosurgical, gynecological, thoracic and urological surgical interventions, including on the prostate and pancreas, as well as the lungs; after dental procedures, tonsillectomy; during operations with the use of a heart-lung machine);
Diseases internal organs with hemorrhagic syndrome;
Premature detachment of the placenta, complicated abortion;
hypoplastic anemia;
state of shock;
Massive transfusions of canned blood in the presence of the likelihood of secondary hypofibrinogenemia;
Burn disease.

Method of application and dosage

Intravenous administration of the drug to adults is indicated in the amount of 4-5 g dissolved in 250 ml of a 0.9% sodium chloride solution. This dosage is used for acute bleeding. The drug is administered within 1 hour. Maintenance therapy - doses of 1 g (in fifty ml) every hour until the cessation of blood loss. But you can not use the product in this way for more than 8 hours. The daily dose of aminocaproic acid ranges from 5 to 30 g.

The daily dosage of Aminocaproic acid for children is:

up to a year - 3 g;
from 2 to 6 years - 3-6 g;
from 7 to 10 years - 6-9 years.

In acute blood loss Aminocaproic acid is indicated for children in such doses:

up to 1 year - 6 g;
2-4 years - from 6 to 9 g;
5-8 years - up to 12 g;
9-10 years - 18 years

Treatment lasts from 3 to 14 days.

If the drug is taken orally, then it should be washed down with sweet water. The initial dose, according to the instructions for Aminocaproic acid, is 5 g, after which the dosage is reduced to 1 g, which must be taken every hour for 8 hours until the bleeding stops. Approximate daily dose is 10-18 g, the maximum is 24 g. The dose of aminocaproic acid for children is 50-100 mg per kg of weight.

Also, the drug is used locally - the bleeding surface is sprayed with a chilled solution or a napkin soaked in the drug is placed on top.

Side effects

From the instructions for Aminocaproic acid, it is known that the drug can cause dizziness, nausea, headache diarrhea, tinnitus, orthostatic hypotension, arterial hypotension, arrhythmia, bradycardia, catarrhal phenomena of the upper respiratory tract, skin inflammation, convulsions, shortness of breath, skin rashes, kidney failure, muscle weakness, hearing loss.

Contraindications for use

The drug is contraindicated in:

Individual intolerance;
Tendencies to thrombosis and thromboembolic diseases;
Kidney diseases with impaired function;
Coagulopathy based on diffuse intravascular coagulation;
DIC;
Pregnancy and lactation;
Violations of cerebral circulation;
Bleeding from the upper respiratory tract of unknown origin.

Use during pregnancy and lactation

The drug is not prescribed to pregnant and lactating women. This remedy inappropriate in cases where there is a possibility of increased blood loss during childbirth, because in postpartum period thromboembolic complications may develop.

Additional Information

In addition to the fact that aminocaproic acid is widely used in surgery to stop bleeding and in blood transfusion, due to its versatility, the range of applications is quite wide.

Aminocaproic acid in the nose is prescribed as an excellent prevention of influenza and SARS, because it strengthens blood vessels in the sinuses, increases blood clotting, and reduces the risk of nosebleeds. In addition, the drug resists the development of allergies and edema, reduces the amount of discharge from the nasal passages.

To protect yourself from viruses, it is necessary to instill aminocaproic acid into the nose 2-3 drops 4 times a day, in the treatment of the disease - every three hours. On average, the course of treatment lasts up to a week.

The advantage of this use of the drug is that it can be instilled during pregnancy. The dosage in this case is 3 drops three times a day. You can also supplement the treatment with vasodilators, if allowed by the doctor.

As such, the modern pharmacological industry does not produce drops, therefore, with medicinal purposes apply a 5% solution of aminocaproic acid.

Terms and conditions of storage

The drug must be stored at temperature regime from 0 to 20 degrees in a dry dark place.

If an intravenous solution is used, then it should be used immediately after preparation and should not be stored further.

Regardless of the form of release, the drug should be stored out of the reach of children.

It is important to note that if there is a precipitate in the solution or if it becomes cloudy, if a suspension or flakes appear, if the package is leaking, the drug becomes absolutely unsuitable for use.

The shelf life of the medicinal product is 3 years.

The pharmaceutical industry does not stand still and every year there are the latest drugs for the treatment of various diseases, including sinusitis. However, many otolaryngologists with extensive work experience and accumulated experience continue to prescribe old and time-tested remedies. An example of such use is the use of aminocaproic acid in the treatment of sinusitis.

Aminocaproic acid belongs to the group of fibrinolysis inhibitors. It exhibits a hemostatic effect and is a specific hemostatic agent. Its use is prescribed for bleeding, the cause of which was the increased dissolution of blood clots and blood clots.

Produced medicinal product many pharmaceutical companies in powder form for internal use and solution for infusion.

The powder contains pure aminocaproic acid without additional substances. The infusion solution is prepared by diluting the acid with aminocaproic water for injection with the addition of sodium chloride under industrial aseptic conditions.

Why doctors prescribe for sinusitis

It would seem that aminocaproic acid is a hemostatic agent and its use in sinusitis cannot bring any benefit. But it is not so. In addition to hemostatic properties, the drug has other actions that make it effective in this disease.

Aminocaproic acid has antiallergic and antiviral effects, strengthens the walls of blood vessels and reduces capillary permeability. Due to the presence of anti-allergic properties, aminocaproic acid helps to fight the signs of allergic sinusitis, as well as eliminate itching, swelling of the mucosa and burning sensation in sinusitis of any nature.

Strengthening and reducing the permeability of capillaries helps prevent nosebleeds caused by their fragility. Signs of capillary fragility may not necessarily be severe bleeding. Quite often, with sinusitis, especially during the use of vasoconstrictors, one can observe the appearance of blood streaks in nasal discharge. Their appearance and will help prevent aminocaproic acid.

Perhaps the most interesting property medicine is its antiviral ability. Studies have shown that aminocaproic acid prevents the binding of viruses to sensitive cells.

In addition, the drug stimulates the cellular and humoral immunity of the body, providing its natural protection.

Thus, all the properties of this drug provide with sinusitis:

elimination of swelling of the mucosa and relief of nasal breathing;
reducing the amount of secreted mucus and improving its outflow;
elimination of dryness, irritation and burning in the nose;
preventing the spread of a viral infection.

Indications for use according to the instructions

Despite the presence of properties that help fight sinusitis and other diseases of the nasopharynx, in official instructions no such evidence can be found. It contains mainly indications associated with increased fibrinolytic activity of the blood, namely:

bleeding during surgery;
hemorrhages from mucous membranes;
hyperfibrinolysis;
parenchymal bleeding;
bleeding with stomach and intestinal ulcers;
premature detachment of the placenta;
during blood transfusion to prevent secondary hypofibrinogenemia.

The instructions for aminocaproic acid powder contain information about the possibility of its use for the prevention and treatment of influenza and other viral infections.

When to use for the nose

The use of the drug locally is possible in infectious and inflammatory diseases of the nasopharynx, which are accompanied by swelling of the mucosa, serous or purulent discharge, signs of an allergic process and nasal congestion. These diseases include:

acute and chronic infectious rhinitis;
allergic rhinitis;
sinusitis;
frontites;
ethmoiditis.

It is important to understand that the use of aminocaproic acid in these diseases is not the mainstay of treatment. It's only auxiliary component combination therapy to help eliminate unpleasant symptoms and speed up recovery.

Features of use in diseases of the nasopharynx

For the treatment of sinusitis may be suitable as infusion solution, and powder. Only the powder will need to be diluted before use at the rate of 1 g per 20 ml of chilled boiled water.

The medicine for sinusitis and other diseases of the nasopharynx can be used in several ways: drops, inhalations, turundas in the nose and rinsing.

Drops

Applying a solution of aminocaproic acid in the form of drops is quite simple. To do this, it is enough to draw it into a pipette or syringe and drip into both nasal passages the number of drops indicated by the ENT doctor. The procedure is repeated up to 5 times a day, unless otherwise directed by the doctor.

Inhalations

For inhalation with medicine you need a nebulizer. The solution of the drug before inhalation is diluted 1 to 1 with a solution of sodium chloride. Other substances are strictly prohibited. The duration of inhalation is from 3 to 5 minutes. It is carried out 1-2 times a day. This use of aminocaproic acid is shown in chronic forms nasopharyngeal diseases.

Washing

Washing the nose with aminocaproic acid can only be carried out by a doctor under conditions medical institution. This use of the drug allows you to quickly get rid of thick serous or purulent discharge, however, may not be safe. The drug in large quantities can provoke severe irritation mucous membrane and push the increase in edema.

Turunds in the nose

Another lung way use of the drug - turundas in the nose. Cotton swabs are moistened with a medicinal solution and placed alternately in the nasal passages for 5-10 minutes.

Important! With sinusitis, it is not advisable to use aminocaproic acid inside. Such use of it is prescribed only for internal bleeding.

Contraindications

The drug is distinguished by its safety in topical application, however, in some cases, its use still needs to be abandoned. These include:

hypersensitivity to the drug;
tendency to embolism and thrombosis;
thrombophilia;
macrohematuria;
period of pregnancy;
lactation;
severe renal and hepatic dysfunction.

Side effects

The instructions for the drug describe only side effects, which can develop with internal or intravenous use. With local use of the drug in rare cases possible development of hypersensitivity reactions, as well as irritation of the nasal mucosa. In such cases, the use should be discontinued and consult a doctor.

Application in childhood

The drug is approved for use in children from infancy. This does not mean that you need to go to the pharmacy for the coveted vial of solution for a cold in a child. First of all, you should consult a doctor who, on the basis of the diagnosis, will prescribe the means necessary for treatment, and it is quite possible that there will also be aminocaproic acid.

Aminocaproic acid is a hemostatic agent that stops bleeding. The drug is available as a solution for topical use. It is prescribed to patients with frequent nosebleeds provoked by fragility. vascular walls during the operation or endoscopic examination in the nasal passages or paranasal sinuses. Aminocaproic acid in the nose of children and adults is often used in ENT practice for infectious and inflammatory diseases.

Properties of aminocaproic acid

The drug belongs to the group of fibrinolysis inhibitors. The substance inhibits the process of dissolution of blood clots and platelets. Acid affects blood clotting factors. Activates special blood proteins that control coagulation and arterial pressure in vessels.

Aminocaproic acid delays physical and chemical processes in the bloodstream, inhibits fibrinolysis both in the early late stages. This occurs by binding plasmin and proteases - trypsin, tissue plasminogen activator, urokinase.

The drug enhances the cohesion (adhesion) of platelets - small cells that create the first blood plug in violation of the integrity of the vessels. Also, the substance strengthens the walls of capillaries and reduces their permeability. The solution has anti-allergic properties, as it inhibits the formation of antibodies in response to an external stimulus.

The medicine improves the functionality of the liver and enhances the work of its detoxification mechanisms.

Caproic acid in the nose also inhibits the fibrinolysis of active substances and proteins in the endothelium ( inner fabric lining the mucous membranes). Therefore, the drug is effective not only when it enters the internal environment, but also when applied topically to the epithelium of the upper respiratory tract.

When hit in systemic circulation the substance is excreted by the kidneys unchanged after 4 hours. In patients with chronic kidney failure acid lingers in the body, accumulates, its concentration in the blood rises sharply.

Indications for prescribing the drug

According to the instructions for use, drops with aminocaproic acid are prescribed in cases where it is necessary to stop bleeding.

Indications for the use of the solution are the following circumstances:

operations in maxillofacial surgery;
pathological fragility of vessels in the nose;
nosebleeds in pregnant women;
pathological conditions associated with high fibrinolytic activity.

The solution is effective for burns of the nasal mucosa and skin.

V pediatric practice acid is prescribed for the treatment of rhinitis in acute respiratory infections and flu.

Features of the use of the solution in otolaryngology

Given the anti-allergic and anti-inflammatory properties of the solution, it is prescribed to patients with ENT diseases.

For children, aminocaproic acid is prescribed for such pathologies:

acute rhinitis of infectious etiology (viral);
chronic year-round runny nose in the acute stage;
acute sinusitis - sinusitis, frontal sinusitis, ethmoiditis;
SARS, influenza;
angina;
adenoids;
tracheitis, bronchitis.

In ENT practice, aminocaproic acid is prescribed only as part of complex treatment diseases. As a standalone drug for the treatment of acute inflammatory processes in the nose and paranasal sinuses, the solution is not used. Acid monotherapy can turn an acute process into a chronic stage.

In the combined treatment of acute respiratory infections and influenza, the drug relieves swelling of the mucosa, reduces hyperemia. After applying the drug, the production of pathological exudate decreases, nasal breathing is partially restored.

Release form and drug treatment regimens

Aminocaproic acid is white matter in the form of crystals or powder. Has no taste and smell. Available as a 5% solution for infusion (intravenous injections). 1 ml of liquid contains 50 mg active substance. The drug is sold in transparent glass bottles or dense polyethylene containers with a volume of 100 and 200 ml.. This form of release is used orally, intravenously and topically. The price varies in the range of 31-75 rubles, depending on the volume and manufacturer.

Based on many years of experience, otolaryngologists have developed regimens for the use of nasal instillation solution in the treatment of patients with rhinitis and sinusitis.

Babies from 1 to 5 years old are instilled 1 drop in each nasal passage 3 times a day. The therapeutic course is 5-7 days.

Aminocaproic acid with a runny nose in children from 5 to 12 years old is used in the amount of 2-3 drops in each nostril, 4 times a day.

Adolescents and adults with sinusitis and acute rhinitis shown 3-4 drops up to 5 times a day.

The drug can be used as prophylactic during the period of increased epidemiological situation during outbreaks of influenza and SARS. Drip 1-2 drops, depending on age during the week.

Aminocaproic acid is not prescribed for children and adults. Oral administration is possible in rare cases, if necessary, to stop bleeding in the organs of the digestive system.

The drug is effective on initial stages inflammation of the pharyngeal tonsil in children preschool age. It reduces swelling and inflammation. The solution is prescribed in combination with antiseptics, antibiotics, glucocorticosteroids (if necessary).

The method of using aminocaproic acid for nosebleeds depends on the intensity of blood loss. With capillary hemorrhage, the solution is dripped in the form of drops. If nose bleed medium degree severity, do tamponade of the nasal passages with a bandage or gauze napkins, impregnated with medicine .

As an antiallergic agent, aminocaproic acid drops reduce symptoms allergic rhinitis due to the effect on the production of histamine. After applying the solution, itching in the nose decreases, swelling subsides, the patient stops sneezing. Pathological exudation is noticeably reduced, viscous and transparent mucus in the nasal passages is eliminated.

To reach the maximum therapeutic effect, you need to bury the medicine according to outside nasal passage. To do this, the head is slightly thrown back and tilted to the side, where drops will drip. If the treatment is to a small child, his head needs to be fixed. In case of accidental contact with the solution in the eyes, the conjunctiva must be quickly rinsed under running water for several minutes. After the drug is instilled, it is recommended to sit with your head tilted for 2-3 minutes, then repeat the manipulation with the second nostril.

Possible side effects

If during nasal instillation medicinal solution got into digestive tract, the patient may develop dyspeptic disorders:

nausea;
discomfort in the epigastric region;
diarrhea.

Rarely, when applied topically, symptoms of inflammation of the upper respiratory tract may increase.

Using large doses acids develop signs of damage to the nervous system:

headaches and dizziness;
noise in ears;
children have seizures.

In preschool children, side effects were recorded in the form of allergic reactions - redness and rashes on the skin, peeling, itching, nasal congestion.

Sometimes patients experience a drop in blood pressure during treatment, which leads to orthostatic hypotension, a condition in which blood pressure drops sharply when changing position, for example, if you quickly get up from a chair or get out of bed. At the same time, a person feels a sharp weakness, lightheadedness, and may lose consciousness.

If the described signs appear, you should reduce the dosage or stop using the solution.

Contraindications for appointment

The instructions for use do not recommend the appointment of aminocaproic acid in the nose of a child with bleeding of unknown origin. to avoid negative consequences.

Contraindications to the appointment of a hemostatic solution:

tendency to thrombosis;
coagulopathy - blood clotting disorders;
diffuse blood clotting inside the vessels;
thromboembolic pathology.

Aminocaproic acid is dangerous in the syndrome of disseminated intravascular coagulation (DIC) - the formation of microscopic blood clots in small capillaries- arterioles, venules.

The drug should not be used in patients with chronic functional diseases kidneys.

An absolute contraindication is a violation of the blood circulation of the brain, which leads to transient ischemic attacks and strokes.

The use of aminocaproic acid in the nose during pregnancy is not recommended, only under strict medical indications and in the absence of alternative treatment.

The drug is not prescribed to women during lactation and infants in the first year of life.

The solution is canceled if individual intolerance, which appears strong burning sensation and itching of the nasal mucosa.

Drugs similar in their pharmacological actions

Analogous drugs include drugs that are produced on the basis of tranexamic acid with antifibrinolytic, anti-inflammatory and antiallergic effects.:

Azeptil (Cyprus);
Gesaksam (Ukraine/Germany);
Gemotran (Ukraine);
Neotranex (Italy);
Trenaxa (India);
Tramix (Ukraine);
Sanger (Ukraine);
Tranestat (Russia);
Transtop;
Tugina (India);
Cyclocapron (Ukraine).

Analogues based on aminomethylbenzoic acid:

Pamba (Germany);
Amben (Russia);
Gumbix (India).

Analogues based on aprotinin - an antienzymatic agent, a protease inhibitor:

Kontrykal (Germany);
Gordoks (Hungary);
Aprotinin (Germany).

Aminocaproic acid is an affordable drug for all patients, regardless of their social status. The drug has emergency care with nosebleeds, allergic reactions. The solution is used to treat the common cold in children with acute respiratory infections. The medicine has serious contraindications. It is not prescribed to patients with blood clotting disorders, patients with a history of strokes, heart attacks, cerebrovascular accidents.