In the article we will consider the instructions for use for glucose solution for infusion. This is a medication intended for carbohydrate nutrition. It has a hydrating and detoxifying effect. An infusion is an intravenous administration of a drug.

Release form

This medical product is produced in the form of a 5% solution for infusion.

It is presented colorless clear liquid 1000, 500, 250 and 100 ml in plastic containers, 60 or 50 pcs. (100 ml), 36 and 30 pcs. (250 ml), 24 and 20 pcs. (500 ml), 12 and 10 pcs. (1000 ml) in individual protective bags, which are packaged in cardboard boxes along with an appropriate number of instructions for use.

A 10% glucose solution is presented as a colorless transparent liquid, 20 or 24 pcs. in protective bags, 500 ml in plastic containers, packed in cardboard boxes.

The active component of this medical product- dextrose monohydrate, additional substance - injection water.

Indications for use

What is the product intended for? Glucose solution for infusion is used:

Contraindications

The list of contraindications for the use of glucose solution for infusion includes the following conditions:

• hyperlactatemia;
• hypersensitivity to the active substance;
• hyperglycemia;
• dextrose intolerance;
• state of hyperosmolar coma.

All this is described in detail in the instructions.

For glucose 5% available additional contraindication. It includes diabetes mellitus uncompensated form.

Additionally for a 10% glucose solution:

Infusions of dextrose solutions in these concentrations are contraindicated within 24 hours after head injuries. In addition, it is necessary to take into account contraindications for medicinal substances added to such solutions.

Can be used during pregnancy and during breastfeeding according to indications.

Dosages and method of administration

Glucose solution for infusion is administered intravenously. The concentration and dosage of this drug is determined depending on the condition, age and weight of the patient. It is necessary to carefully monitor the level of dextrose in the blood. As a rule, the drug is injected into a peripheral or central vein, taking into account the osmolarity of the injected solution. The administration of a 5% hyperosmolar glucose solution can cause phlebitis and irritation of the veins. Whenever possible, during the use of all parenteral solutions, it is recommended to use filters in the supply line of infusion solutions.

• as a source of carbohydrates and for extracellular isotopic dehydration: with a body weight of 70 kg - from 500 to 3000 ml per day;
• for breeding parenteral drugs(in the form of a base solution) - from 100 to 250 ml per single dose of the drug.

• for extracellular isotopic dehydration and as a source of carbohydrates: for weight up to 10 kg - 110 ml/kg, 10-20 kg - 1000 ml + 50 ml per kg, more than 20 kg - 1600 ml + 20 ml per kg;
• for breeding medications(base solution): 50-100 ml per dose of the drug.

In addition, a 10% solution of the drug is used in therapy and to prevent hypoglycemia and for rehydration in case of fluid loss. Higher daily dosages are determined individually, taking into account age and body weight. The rate of drug administration is selected depending on clinical symptoms and the patient's condition. To prevent hyperglycemia, it is not recommended to exceed the dextrose processing threshold, so the rate of drug administration should not be higher than 5 mg/kg/minute.

Side effects

Most common adverse reactions for infusion is:

Similar side effects are possible in patients with a corn allergy. They may also occur as other symptoms such as hypotension, cyanosis, bronchospasm, pruritus, angioedema.

If symptoms or signs of hypersensitivity reactions develop, administration should be discontinued immediately. The medicine should not be used if the patient has allergic reactions to corn and its processed products. Taking into account clinical condition the patient, the characteristics of his metabolism (threshold of dextrose utilization), the speed and volume of infusion, intravenous administration can lead to the development of electrolyte imbalance (namely: hypophosphatemia, hypomagnesemia, hyponatremia, hypokalemia, overhydration and congestion, including symptoms of hyperemia and pulmonary edema), hyperosmolarity, hypoosmolarity, osmotic diuresis and dehydration. Hypoosmotic hyponatremia can provoke headache, nausea, weakness, convulsions, cerebral edema, coma and death. In case of severe symptoms of hyponatremic encephalopathy, emergency treatment is necessary. medical care.

An increased risk of developing hypoosmotic hyponatremia is observed in children, the elderly, women, postoperative patients and people with psychogenic polydipsia. The likelihood of developing encephalopathy is slightly higher in children under 16 years of age, premenopausal women, patients with central nervous system diseases and patients with hypoxemia. Regular monitoring is required laboratory research to monitor changes in fluid levels, electrolyte levels and acid balance during long-term parenteral therapy and assessment of the doses used.

Take special care when using this drug

With extreme caution this medicine prescribed to patients with high risk electrolyte and water imbalance, which is aggravated by increasing free water load, the need to use insulin or hyperglycemia. Large volume infusions are performed under supervision in patients with symptoms of cardiac, pulmonary or other failure, as well as overhydration. When administering a large dose or long-term use When taking medication, you need to monitor the concentration of potassium in the blood and, if necessary, take potassium supplements.

The administration of glucose solution is carried out with caution in patients with severe forms of exhaustion, traumatic brain injury, thiamine deficiency, low dextrose tolerance, electrolyte and water imbalances, ischemic stroke in acute forms and in newborns. In patients with severe malnutrition, the introduction of nutrition can lead to the development of refeeding syndromes, characterized by an increase in intracellular concentrations of magnesium, phosphorus and potassium due to increased anabolism. In addition, thiamine deficiency and fluid retention may develop. To prevent the development of such complications, it is necessary to ensure careful monitoring and increase the intake of nutrients, avoiding excessive nutrition.

Drug interactions

Concomitant use of steroids and catecholamines reduces glucose absorption. It is possible that there may be an impact on the water-electrolyte balance and the appearance of glycemic effects when sharing With medications, influencing it and having hypoglycemic properties.

Price of glucose solution for infusion

The cost of this pharmacological drug is approximately 11 rubles. It depends on the region and pharmacy chain.

The article presented a description of a glucose solution for infusion.

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Glucose is absorbed very well and quickly by the body, and also saturates it with energy. For quick recovery strength and use it. It is used for many ailments. Such as: under stress, lack of sugar, low blood pressure, bad work liver and heart.

Glucose It is a very easily digestible source of nutrition for the human body, which can increase both energy reserves and improve the body's performance functions.

Glucose droppers are used for detoxification, i.e. removing toxins from human body and to replenish the fluid lost in it.

As a general maintenance therapy, glucose is used if a person experiences general physical exhaustion.

Glucose solution can be prescribed for:

intoxications and poisonings

for hepatitis and liver diseases

for diseases of the blood system

for severe diarrhea

and other problems.

Glucose is a substance that quickly replenishes nutritional deficiencies in the human body in order to improve tone and increase energy.

Once I was put on a glucose drip for poisoning, because I felt simply terrible and had a huge loss of strength. I agree with one answer that glucose is not prescribed to detoxify the body. The most important task Glucose is to provide nutrition to the body as soon as possible.

Also, as far as I know, glucose is very useful for low blood pressure.

Glucose is the most versatile source of energy, as it is easily absorbed and is subject to rapid breakdown in the body.

Glucose is dripped:

1) For various types of intoxication and poisoning;

2) When falling blood pressure in order to improve blood pressure;

3) In case of cardiac dysfunction;

4) In case of dysfunction of a=liver;

5) To increase sugar levels if they have dropped significantly;

6) After severe stressful situations;

7) When the body is depleted in order to normalize metabolism.

Most often, glucose is dropped to remove signs of intoxication, that is, to destroy toxins in the body or to wash away unwanted drugs. Very effective and fast-acting method. They are also dripped after operations to speed up the healing of soft tissues.

Several times I was faced with the need to inject glucose into my animals. The point is that this good source nutrition. If for some reason, for example, animals cannot eat, in order to maintain their health they do not drip, in fact they do not feed in this way.

Glucose droppers are given to a person for certain diseases.

Glucose is administered intravenously for hypoglycemia, when blood sugar levels are low. It is necessary for those who have infectious diseases.

Glucose is administered at sharp decline pumping function of the heart (decompensation of cardiac activity).

Glucose is necessary for liver diseases, pulmonary edema, hemorrhagic diathesis (increased bleeding), shock and sharp drop blood pressure (collapse).

Glucose solution is used mainly to replenish fluid in the body. Droppers are prescribed for

low blood glucose levels

a sharp decrease in blood pressure

increased bleeding

in the postoperative period

poisoning caused by microbes that entered the body with food

Glucose droppers have been used in medicine for a long time.

Glucose is a source of energy that is easily absorbed. Studies have also been conducted that have proven that glucose relieves stress.

A glucose drip is given in the following cases:

firstly, to improve blood pressure, with a sharp drop in blood pressure,

secondly, to improve liver function, after a drip it works better,

thirdly, to improve metabolism in the human body, as well as when the body is exhausted,

fourthly, to improve the functioning of the heart muscle,

fifthly, if your blood sugar level has dropped significantly,

sixthly, if a person is in a state of shock,

seventhly, in case of alcohol poisoning.

Glucose is a universal source of energy, as it is immediately broken down in the body and is very easily absorbed. What they write that they say is for detoxification or fluid replenishment is bullshit, since the glucose solution almost immediately leaves the bloodstream (5-10 minutes after entering the bloodstream) into the tissues where it is already metabolized, providing cells with the necessary energy, in addition it draws water onto itself, so there is no way to flood it. For detoxification, more crystalloids and less colloids are used (for example, regular saline, rheosorbilact, sorbilact, rheopolyglucin, ringer, etc.). Use a 5% glucose solution.

A 40% solution is also used, which is administered intravenously in a stream in case of hypoglycemic coma (as a rule, with an overdose of insulin), the patient is literally at the end of a needle, as soon as you begin to inject it, he comes to his senses. It is also an excellent remedy for relieving acetone syndrome in children. As soon as you smell acetone from your mouth, let the child drink 10 ml of 40% glucose, if everything is done on time, vomiting, etc. can be avoided.

Instructions for use of Glucose 5% and 40% solution for injection
for dehydration and intoxication of the animal body
(developer organization: CJSC NPP "Agropharm", Voronezh)

I. General information
Trade name medicinal product: Glucose 5% and 40% solution for injection (Glucosi 5%, 40% Solutio proinjectionibus).
International generic name: dextrose.

Dosage form: solution for injection.
Glucose 5% and 40% solution for injection as an active ingredient contains, respectively, 5 g or 40 g of crystalline hydrated glucose, as well as excipients: 0.026 g of sodium chloride, hydrochloric acid - up to pH 3-4, water for injection - up to 100 ml. By appearance the drug is a colorless or slightly yellowish transparent liquid.

Glucose solutions of 5% and 40% are produced packaged in 100 ml glass bottles made of neutral glass, sealed with rubber stoppers reinforced with aluminum caps.
The shelf life of the medicinal product, subject to storage conditions, is 2 years from the date of production. After opening the bottle, unused medicinal product cannot be stored.
It is prohibited to use the medicinal product after the expiration date.
Glucose 5% and 40% solution for injection is stored in the manufacturer's sealed packaging in a dry place, protected from light, separately from food and feed, at a temperature of 0°C to 25°C. Solutions should be stored out of the reach of children.
Unused medicinal product is disposed of in accordance with legal requirements.

II. Pharmacological properties
Glucose 5% and 40% injection solution refers to carbohydrate nutrition preparations and tissue repair stimulators.
Glucose is involved in various metabolic processes in the body, enhances redox processes in the body, and improves the antitoxic function of the liver. Entering the tissues, it is phosphorylated, turning into glucose-6-phosphate, which is actively involved in many parts of the body’s metabolism.
Isotonic, 5%, glucose solution has a detoxifying, metabolic effect, is a source of valuable easily digestible nutrient. When glucose is metabolized in tissues, a significant amount of energy is released, which is necessary for the functioning of the body.
Hypertonic, 40%, glucose solution increases osmotic pressure blood, improves metabolic processes, antitoxic liver function and heart function, expands blood vessels, increases diuresis. Glucose stimulates the synthesis of hormones and enzymes, increases protective forces animal body.
After administration, the drug is quickly absorbed from the injection site and distributed in the organs and tissues of the animal.

Glucose 5% and 40% in terms of the degree of impact on the body is classified as low-hazard substances according to GOST 12.1.007 (hazard class 4).

III. Application procedure
Glucose 5% and 40% is used in animals with large losses of body fluid (bleeding, toxic dyspepsia), shock, intoxication, metritis, vaginitis, as well as for dissolving various medications.

Contraindications to the use of the drug are the animal’s increased individual sensitivity to dextrose and diabetes mellitus.

Glucose 5% is used subcutaneously or intravenously. Glucose 40% - only intravenously.

Depending on the severity of the disease, the drug is administered to animals 1-2 times a day in the following doses:

When administered subcutaneously, the dose of the drug is administered in fractions different places bodies.
Doses and timing of use depend on the weight of the animal and the course of the disease.

No overdose symptoms have been identified in animals.
The specific effects of the drug upon its first use and withdrawal have not been established.

Avoid skipping the next dose of the drug, as this may lead to a decrease in its therapeutic effectiveness. If one dose is missed, the use of the drug is resumed as soon as possible at the same dosage and according to the same regimen.

When using Glucose 5% and 40% in accordance with these instructions side effects and no complications are observed in animals.
The use of glucose solution does not exclude the use of other medications.
Livestock products are used without restrictions during and after use of the drug.

IV. Personal prevention measures
When carrying out therapeutic and preventive measures using Glucose, you should follow general rules personal hygiene and safety precautions provided when working with medicines. While working with the drug, do not drink, smoke or eat. Hands should be washed after finishing work warm water with soap.
People with hypersensitivity to the components of the drug should avoid direct contact with the solution. If the drug accidentally comes into contact with the skin or mucous membranes, they must be washed with running water and soap. If allergic reactions or if the drug accidentally enters the human body, you should immediately contact medical institution(bring with you the instructions for use of the drug or the label).

Empty drug bottles must not be used for household purposes; they must be disposed of with household waste.

Manufacturer: CJSC NPP "Agropharm", Russia, 394087, Voronezh region, Voronezh, st. Lomonosova, 114-b.

With the approval of this instruction, the instructions for the use of Glucose 5% and 40% solution for injection, approved by Rosselkhoznadzor on May 22, 2008, become invalid.

Farm group:

Release form: Liquid dosage forms. Solution for infusion.

General characteristics. Compound:

Pharmacological properties:

Indications for use:

Important! Get to know the treatment

Directions for use and dosage:

Features of application:

Side effects:

Interaction with other drugs:

Contraindications:

Overdose:

Storage conditions:

Store at temperatures from 5 to 30 °C. Keep out of the reach of children. Freezing the drug, provided the bottle remains sealed, is not a contraindication to the use of the drug. Non-wettability inner surface bottles is not a contraindication to the use of the drug. If the contents become cloudy, do not use.
Shelf life - 2 years. Do not use after expiration date.

Vacation conditions:

By prescription

Package:

200 ml or 400 ml in glass bottles for blood, transfusion and infusion drugs with a capacity of 250 ml or 450 ml, sealed with rubber stoppers and crimped with aluminum caps. 1 bottle with instructions for use in a cardboard pack.

15 or 28 bottles with a capacity of 250 ml or 15 bottles with a capacity of 450 ml in a corrugated cardboard box with spacers and grids (sockets) without prior packing. Instructions for use are placed in the box in an amount equal to the number of bottles (for hospitals).