Cerucal is usually prescribed for vomiting and weakened gastric and intestinal motility. The main active ingredient of the drug - metoclopramide - is considered potent, therefore it is possible to treat children with Cerucal only from the age of two. In very rare cases the drug is prescribed with caution to newborns, but the muscles of children's organs do not always respond positively to the effects of such substances. The minimum doses of Cerucal are given to babies if it is not possible to use another remedy.

General description of the drug

Cerucal is medicinal product whose main task is to stimulate motor skills digestive system. It is also effective in suppressing the gag reflex. It is worth noting the fact that the use of the remedy can help with severe hiccups.

The manufacturers of this drug are the Hungarian company Teva Private Co. and the Croatian company Pliva. Concerning registration certificate, then it is issued to the Israeli company Teva.

The product is available in tablets and ampoules. It is worth paying attention to the fact that with severe vomiting, when food and liquid do not linger in the body even for ten to fifteen minutes, it makes no sense to use tablets, they simply do not have time to dissolve and leave the body with food. Therefore, with such severe symptoms it is better to use injections.

Attention! With such severe vomiting, dehydration can occur, so you should not delay contacting a doctor.

The undoubted advantage of Cerucal is an adequate price. On average, a package of Cerucal containing fifty tablets can be purchased for 140 rubles. As for the injection solution, ten ampoules cost about 250 rubles.

Now with regard to the composition of the drug. Main active substance is metoclopramide hydrochloride. Due to its presence in the composition of Cerucal, the work of receptors is blocked, through which impulses from an irritated digestive system enter the vomiting center of the brain.

Another action of Cerucal is the stimulation of the smooth muscles of the stomach. As a result, the speed of food from the stomach to the intestines increases. At the same time, the stomach is protected from bile entering it, and the esophagus is protected from food. Moreover, Cerucal provides positive influence on intestinal motility and thereby minimizes the likelihood of constipation.

Indications for use

As we have already said, most often Cerucal is prescribed for severe vomiting. In addition, the drug is used to treat such pathologies:

• dyskinesia biliary tract;
• stenosis of the duodenum and gastric pylorus (narrowing of the lumen);
• paresis of the stomach motor functions intestines;
• decrease in muscle tone of the digestive system;
• increased gas production.

Contraindications and side effects

First of all, it is worth noting that Cerucal should not be given to children under two years of age. In this case, you risk causing severe side effects and worsening of the condition. little patient.

For older children, the use of Cerucal should occur only under the supervision of the attending physician. In no case should you self-medicate.

After taking the drug in in large numbers Children may experience the following side effects:

• severe headaches;
• lethargy and weakness;
• drowsiness;
• increased levels of anxiety;
• spasms of the facial and cervical muscles;
• symptoms of shaking paralysis;
• speech disorder.

Interestingly, in adults, Cerucal can cause only some of the described side effects affecting only the digestive system. But in a child, the effect of the drug also extends to the central and peripheral nervous system.

The use of Cerucal for both adults and children is categorically contraindicated in the following pathologies:

• intestinal obstruction;
• violation of the integrity of the walls of the digestive system;
• bleeding from organs gastrointestinal tract;
• tendency to convulsions;
• tics in the upper body;
• epilepsy;
• have chronic or acute diseases liver or kidneys;
• bronchial asthma.

Do not forget about individual intolerance individual components in the composition.

As you can see, it is possible to use Cerucal only as prescribed by the attending physician. This is especially true for the treatment of children. Therefore, if your child suddenly starts vomiting, then you should not immediately run for this remedy.

The best option would be to call an ambulance. Doctors on site will be able to assess the threat to the life and health of the baby and provide first aid. And after the arrival of the ambulance, you must definitely go for a consultation with a pediatrician, who, after special survey will be able to determine the cause of vomiting and prescribe adequate treatment.

It is worth paying attention to the fact that with the appearance of nausea associated with disturbances in work vestibular apparatus or psychogenic factors, the use of this drug is ineffective.

How to give Cerucal to a child: dosage and treatment regimen

Cerucal tablets

• Adolescents over 12 years of age take 10 mg 3-4 times a day;
• dosage for children from three years old is calculated as follows: 0.1 mg per kilogram of body weight. In some cases, it may be necessary to increase the dose. In this case, the maximum dosage per kilogram of body weight is 0.5 milligrams;
• Tablets should be taken half an hour before meals with half a glass of water.
• On average, the course of treatment is approximately one to two months, but in the case advanced disease it may be necessary to extend it up to six months as prescribed by the doctor.

It is worth paying attention to the fact that if a child has acute and chronic diseases renal dose of the drug should be adjusted individually. But this, again, must be done by a doctor.

Cerucal solution in ampoules for injections

• The drug is administered intravenously or intramuscularly;
• Adolescents over 12 years of age are most often prescribed 2 ml of the drug 3-4 times a day;
• For children over three years old, the injection is calculated on the basis of the following proportion: 0.1 mg per kilogram of body weight. Just as with tablets, it is possible to increase the amount of the drug up to 0.5 milligrams per kilogram of body weight.

With prolonged vomiting, a visit to the doctor is mandatory.

Cerucal is a drug that normalizes the motility of the stomach and intestines, as well as stopping vomiting. Cerucal is used to stop vomiting of any origin in children and adults, to expand the lower part of the stomach in the area of ​​​​its connection with the duodenum with pyloric stenosis, to eliminate heartburn and discomfort in the epigastrium, in complex therapy reflux esophagitis, as well as atony of the intestines and stomach. In addition, Cerucal can be used to prepare a person for gastroesophagoscopy and probing, as it relaxes the muscles of the esophagus and stomach, facilitating diagnostic manipulation.

International name, release forms and composition of Cerucal

Cerucal is currently available in two dosage forms:
1. Tablets for oral administration;
2. Solution for intravenous and intramuscular administration.

Tablets are usually called simply Cerucal, and the injection solution is called Cerucal injections or Cerucal in ampoules.

International generic name(INN) Cerucala - Metoclopramide. The INN is the official, common name for the active ingredient in a medicinal product. Since in Tserukal active substance is metoclopramide, then the INN of the drug is Metoclopramide, respectively.

As an active substance, both dosage forms of Cerucal include metoclopramide in various dosages. So, one tablet contains 10 mg of metoclopramide, and in solution its concentration is 5 mg per 1 ml. Since the solution is poured into hermetically sealed 2 ml ampoules, one ampoule contains 10 mg of metoclopramide. Thus, a solution from one ampoule and a Cerucal tablet contain the same amount of active substance. This ratio can be used to convert the number of tablets required for taking into ampoules and vice versa.

Cerucal tablets as auxiliary components contain the following substances:

• Potato starch;
• Gelatin;
• Silica;
• magnesium stearate.

Cerucal solution as excipients contains the following:

• sodium sulfite;
• Disodium edetate;
• Sodium chloride;
• Water for injections distilled sterile.

Cerucal tablets are colored in White color, have a round flat shape and a risk on one side, and are produced in cardboard packs of 50 pieces. The solution is a clear, colorless liquid and is available in 2 ml glass ampoules packed in carton boxes 10 pieces. Ampoules with a solution are made of transparent glass, on which three stripes are applied - blue at the bottom, green at the top and white at the transition of the bottle to the narrow sealed part. On some ampoules, instead of a white strip, a notch and a dot above it may be applied.

Cerucal - therapeutic effect

Cerucal has an antiemetic and anti-icotic effect due to the suppression of these reflexes at the level of the central nervous system. All other therapeutic effects of Cerucal are derived from these main ones.

The action of the drug is carried out due to its penetration into the bloodstream and brain, and blocking dopamine and serotonin receptors in all organs and tissues. As a result of blocking receptors in the brain, its special zone, called the vomiting center, ceases to function, as a result of which irritants from the organs of the digestive and respiratory tract are not processed, and vomiting reflex does not occur. Thus, there is a relief of vomiting. And since the vomiting center of the brain is also responsible for hiccups, both vomiting and hiccups are suppressed at the same time.

In addition to stopping vomiting and hiccups, Cerucal effectively eliminates the constant and painful nausea caused by various reasons, except for motion sickness.

In addition, due to the effect on dopamine and serotonin receptors in organs digestive tract, Cerucal has the following therapeutic effects:

• Reduces motor and contractile activity the esophagus, which helps to expand its lumen and facilitate the passage of a food bolus through it;
• Increases the tone of the esophageal sphincter that separates it from the stomach. As a result, the number of gastroesophageal refluxes is prevented and reduced;
• Accelerates the transition of the food bolus from the stomach to the duodenum, eliminating the feeling of heaviness and discomfort;
• Accelerates the movement of the food bolus through the intestines, stimulating its peristalsis and without causing diarrhea;
• Normalizes the release of bile in response to food entering the intestine;
• Reduces spasm of the sphincter of Oddi, which is located in the junction of the bile duct and duodenum. Due to this, bile regularly leaves the gallbladder and enters the duodenum without lingering in the duct;
• Normalizes the contractile activity of the gallbladder, eliminating its dyskinesia.

Cerucal does not change the level of secretion gastric juice, pancreatic enzymes and bile.

The therapeutic effect of Cerucal develops one hour after ingestion, 10-15 minutes after intramuscular injection and a few minutes after intravenous administration. The duration of action is determined by the route of administration of the drug and is 30 minutes for intravenous injection, 1.5 - 2 hours for intramuscular and 6 hours for a tablet taken orally.

Indications for use Cerucal (tablets and ampoules)

Cerucal tablets have a narrower range of indications for use compared to the solution. Therefore, tablets are usually used at home on the recommendation of a doctor, and the solution is used in conditions medical institution to achieve certain therapeutic effects.

Tablets and solution Cerucal

Indications for the use of tablets and Cerucal solution are the following conditions and diseases:

• Vomiting of any origin;
• Nausea of ​​any origin;
• Hiccups of any origin;
• Atony and hypotension of the stomach and intestines;
• diabetic gastroparesis ( complete absence contractions of the stomach);
• Symptoms of indigestion (belching, heartburn, flatulence, etc.) with irritable stomach syndrome, reflux esophagitis, pyloric stenosis and biliary dyskinesia;
• As part of the complex therapy of peptic ulcer of the stomach and duodenum, cholelithiasis and gastritis.

Solution for injection Cerucal

Solution for injection Cerucal, in addition to the above diseases, is indicated for use in the following conditions:

• To facilitate duodenal sounding;
• To speed up the passage of the food bolus through the stomach and small intestine during the x-ray examination these bodies.

In principle, both dosage forms of Cerucal are used for the same conditions, but the solution is additionally used for diagnostic manipulations.

Instructions for use of the drug Cerucal

What do you prefer - pills or injections?

Tablets and injections of Cerucal are used to achieve the same therapeutic effects associated with the need to stop vomiting and accelerate the movement of food through the stomach and intestines.

Tablets are preferred in cases where a relatively long therapeutic effect is needed, since their action lasts for 5.5 to 6 hours. As a rule, this is a complex therapy for various chronic diseases of the digestive tract, in which the movement of the food bolus through the intestines and stomach is disturbed, as a result of which symptoms of dyspepsia develop (heartburn, flatulence, heaviness in the stomach, etc.). Usually Cerucal is used in the complex therapy of reflux esophagitis, gastritis, peptic ulcer of the stomach and duodenum, pyloric stenosis and biliary dyskinesia, in which food stagnates in the stomach and intestines, causing unpleasant symptoms.

For vomiting, hiccups, and nausea, the choice between pills and injections is based on the person's ability to take the drug by mouth. In other words, if a person can swallow a pill and not vomit for 15-20 minutes after that, then this particular form of the drug should be chosen. And only if it is impossible to take Cerucal in tablets to stop vomiting, hiccups and nausea, injections should be used. However, at the first opportunity, Cerucal injections should be replaced with tablets.

With diabetic gastroparesis, it is optimal to administer Cerucal intramuscularly in the morning after breakfast, and take it in tablets during the rest of the day.

For diagnostic manipulations, such as duodenal probing, x-rays of the small intestine and stomach, intravenous or intramuscular injection Cerucal solution, since in this case its action comes on quickly and lasts a short period of time (no more than 2 hours), which is very convenient. At injection Cerucal the stomach and intestines are freed from the food bolus, the insertion of the probe is facilitated and contrast agent, which provides optimal conditions for high-quality diagnostics. Moreover, these effects do not last long and, therefore, do not cause concern to a person after the procedure is completed.

For children over 14 years of age, you can follow the recommendations described above for choosing the dosage form of Cerucal. Children aged 2 to 14 years should use Cerucal exclusively in the form of injections, since the solution allows you to accurately dose the drug.

Cerucal tablets - instructions for use

Tablets should be taken orally half an hour before meals, swallowing whole, not chewing, biting or crushing in other ways, and washing down large quantity water (100 - 200 ml).

Between doses of tablets, approximately equal intervals should be maintained, lasting at least 6 hours, since this is how long the effect of the drug lasts. It is recommended to take tablets every 5 to 6 hours during the daytime, and take a longer break during the night's sleep.

At various diseases gastrointestinal tract, accompanied by a violation of the passage of food (reflux esophagitis, gastritis, peptic ulcer, biliary dyskinesia, pyloric stenosis, etc.), adults take Cerucal in the same dosage - 1 tablet 3-4 times a day. Children aged 14 - 18 years in the presence of the same diseases of the digestive tract should take Cerucal 1/2 - 1 tablet 2 - 3 times a day. The duration of therapy ranges from 4 - 6 weeks to six months, depending on the rate of cure of the underlying disease. Reception of Cerucal is usually stopped after the course of treatment of the disease is completed.

To stop the resulting vomiting, hiccups and nausea, it is recommended to take one tablet at a time. If it has not worked within an hour, then you can take another tablet of Cerucal. The third tablet can be taken only after six hours.

If nausea, vomiting and hiccups are not one-time, but constant, accompanying any diseases or conditions, then Cerucal is taken for a long time according to the same scheme as in the composition complex treatment pathologies of the gastrointestinal tract. That is, adults over 18 years old take 1 tablet 3-4 times a day, and children from 14 to 18 years old - 1/2-1 tablet 2-3 times a day. In this case, the drug is continued until the condition normalizes and the painful symptoms disappear.

The maximum allowable single dosage of Cerucal for adults is 20 mg (2 tablets), and the daily dose is 60 mg (6 tablets). For teenagers maximum allowable dosages two times less, that is, a single dose is 10 mg (1 tablet), and a daily dose is 30 mg (3 tablets).

Cerucal injections (in ampoules) - instructions for use

Cerucal solution is administered intramuscularly or intravenously by jet. The ampoule with the solution is opened immediately before the injection and used for a maximum of 15-30 minutes. The opened ampoule cannot be stored until the next injection. It is only allowed to store an open ampoule for a maximum of several hours in the refrigerator. In this case, the hole in the ampoule should be plugged with sterile cotton, bandage or adhesive tape.

For intramuscular injection, it is necessary to use relatively thick and long needles, and for intravenous, on the contrary, thin and short ones. In principle, in case of urgent need, an intravenous injection can be made with an intramuscular needle. But intramuscular injection under no circumstances should it be done with an intravenous needle, since it is too short and may not reach the muscles through the layer of skin and subcutaneous tissue. As a result, the drug will be subcutaneous tissue, from where it will be very poorly absorbed into the blood and, accordingly, will not therapeutic effect. Therefore, you should carefully purchase injection syringes, indicating to the pharmacist which needle is needed in this case. Some syringes are sold only with thin intravenous needles, in which case you will need to purchase intramuscular needles separately. It is optimal to do this in Medtekhnika stores.

To produce an intramuscular or intravenous injection, open the ampoule, take a new sterile syringe from the package, put a needle on it and dial required amount solution. Then the syringe is turned upside down with a needle and, holding it in a vertical position, tap on its wall with a fingernail in the direction from the piston to the needle holder so that air bubbles come off and rise to the surface of the solution. Then lightly press on the piston, releasing a few drops of the solution, along with which air is removed. After completing these manipulations, the syringe is laid aside on a clean surface or in a sterile tray and a site is prepared for intravenous or intramuscular injection.

Intramuscular injection is best done in the upper outer-lateral part of the thigh, the upper third of the upper arm, or in the abdomen (if the person does not have excess weight), since it is in these places that the muscles are closest to the skin and the risk of injecting the solution into subcutaneous layer minimal. The solution should not be injected into the buttock, since the muscles lie very deep in this part of the body and the risk of injecting the drug into the subcutaneous fatty tissue is high.

The selected site for intramuscular injection is wiped with a cotton swab moistened with an antiseptic, for example, alcohol, chlorhexidine, etc. If injections have already been made in this area, then a new place should be found by eye so that the new injection is at a distance of 1 cm from each previous hole. In the selected place, the needle is quickly inserted to the end, holding it perpendicular to the skin. Then slowly release the solution into the tissue, press the skin on both sides of the needle with the index and middle fingers, and remove it. The injection site is again wiped with an antiseptic.

Intravenous injection should only be done by a qualified nurse or doctor, as if the drug is not injected correctly into the perivenous space, irritation and severe allergic reactions. The solution is injected in a jet, that is, the required amount of Cerucal is drawn into a syringe, a vein is pierced and slowly released into the blood.

For the relief of nausea, vomiting and hiccups of any origin, as well as for fast elimination dyspeptic phenomena (heartburn, flatulence, heaviness in the abdomen, etc.) in diseases of the gastrointestinal tract associated with a violation of the passage of food (reflux gastritis, peptic ulcer, gastritis, biliary dyskinesia and pyloric stenosis), a single dose of 10 mg is administered ( whole ampoule) solution intravenously or intramuscularly. If 30 minutes after intramuscular injection or 15 minutes after intravenous vomiting, nausea or hiccups have not stopped, then another 10 mg of Cerucal is administered. The next injection of the drug can be carried out only after 3 hours.

If a person is concerned persistent nausea, vomiting and hiccups of any origin, or he is undergoing therapy for gastrointestinal diseases associated with impaired passage of food through the intestines and stomach, then it is preferable to take Cerucal tablets. But if it is impossible to drink tablets, injections are allowed for a maximum of 2 to 4 weeks. In this case, the Cerucal solution for stopping hiccups, nausea and vomiting, as well as dyspeptic manifestations of gastrointestinal diseases, is administered intramuscularly in one ampoule 3-4 times a day for adults, and half an ampoule 3 times a day for children 14-18 years old.

In principle, the solution is only a means emergency assistance when you need to urgently and quickly normalize a person's condition, eliminating painful symptoms. And after the ambulance, he is transferred to take Cerucal tablets, and they do it as soon as possible.

In children 2-14 years old, Cerucal solution is used according to the same rules as in adults, however, the dosage is determined by body weight and is as follows:

• Child weighs less than 20 kg- a single dosage is 0.4 ml of solution, which corresponds to 2 mg of the active substance. The maximum daily dosage is 10 mg (2 ml of solution);
• Body weight of the child 20 - 30 kg- a single dosage is 3 mg (0.6 ml of solution), daily - 15 mg (3 ml of solution);
• Body weight of the child 30 - 50 kg- a single dosage is 5 mg (1 ml of solution), and a daily dose is 25 mg (5 ml of solution).

Children weighing more than 50 kg, regardless of age, should receive Cerucal in dosages for adolescents from 14 to 18 years old.

To prepare for probing the duodenum, x-ray of the stomach or intestines, Cerucal is administered to adults and adolescents over 14 years old, 1-2 ampoules intravenously 10 minutes before the start of the diagnostic study. For children aged 2-14 years, the dose is calculated individually according to body weight, based on the ratio of 0.1 mg per 1 kg of weight, and is also administered intravenously 10 minutes before the start of the examination.

In order to prevent nausea and vomiting in people receiving cytostatic treatment, Cerucal is used according to two possible schemes:
1. Intravenous drip solution for 15 minutes at a dosage calculated according to the ratio of 0.2 mg per 1 kg of body weight, half an hour before the start of treatment with a cytostatic. Then Cerucal in the same dosage is administered intravenously in a stream through 1.5, 3.5, 5.5 and 8.5 hours after the end of the cytostatic;
2. Long-term continuous drip administration of Cerucal at the rate of 0.5 mg per 1 kg of weight per hour. The calculated amount of the drug is administered two hours before the start and within a day after the end of the use of the cytostatic.

For drip long-term administration of Cerucal, it is diluted in physiological saline or 5% glucose.

Cerucal - dosage for various diseases

Cerucal tablets for all indicated conditions are used in the following identical dosages:

• Children 14 - 18 years old - 1/2 - 1 tablet 2 - 3 times a day;
• Adults over 18 years old - 1 tablet 3 to 4 times a day.

The maximum allowable single dosage of Cerucal is 20 mg (2 tablets) for adults and 10 mg for adolescents, and the daily dose is 60 mg (6 tablets) for adults and 30 mg for adolescents.

Cerucal solution is also used in the same dosages for the indicated diseases and conditions:

• Children over 14 years old and adults - 1 ampoule 1-3 times a day;
• Children 2 - 14 years old - calculated individually according to the ratio of 0.1 - 0.5 mg per 1 kg of weight.

With liver pathologyaccompanied by ascites, the usual dosage is divided in half. In case of kidney pathology, the dosage of Cerucal is prescribed on the basis of creatinine clearance, determined by the Reberg test. If the creatinine clearance is less than 10 ml / min, then Cerucal can be taken only 1 tablet or 1 ampoule 1 time per day. With a creatinine clearance of 11 to 60 ml / min, Cerucal is allowed to take 15 mg per day, divided into two doses - 10 mg in the morning (1 whole tablet or 1 ampoule) and 5 mg in the evening (half a tablet or 1 ml of solution). With a creatinine clearance of more than 60 ml / min, Cerucal should be taken in the usual dosages according to age.

special instructions

During the entire period of therapy with Cerucal, alcohol should be avoided.

Adolescents, the elderly over 65 years of age and people suffering from kidney disease, liver disease, bronchial asthma and hypertension have more high risk development side effects. If they appear, then the drug must be discontinued.

While taking Cerucal, the concentrations of bilirubin, protein, AST, ALT and prolactin in the blood plasma may change. These changes are reversible and do not require discontinuation of the drug.

It is not recommended to use the drug for epilepsy, glaucoma and extrapyramidal disorders, since it is possible to aggravate the course of the disease.

Influence on the ability to control mechanisms

Cerucal can reduce the rate of reactions, so during therapy it is necessary to refrain from potentially dangerous species activities related to the need to control mechanisms.

Compatibility with other drugs

Anticholinergics (Atropine, Scopolamine, Promethazine, Diphenhydramine, etc.) weaken the effect of Cerucal. And Cerucal weakens the effect of Levodopa, Pergoline and H2-histamine blockers (Ranitidine, Famotidine, etc.).

Cerucal slows down the absorption into the bloodstream from the intestines of Digoxin and Cimetidine, but accelerates that for antibiotics (Tetracycline, Ampicillin, etc.), Paracetamol, Aspirin, Levodopa, lithium preparations and alcohol.

When taken simultaneously, Cerucal leads to an increase in the concentration of lithium and bromocriptine in the blood. In addition, Cerucal enhances the effects of alcohol and sedatives, and prolongs the action of succinylcholine. Cerucal also changes the effects of tricyclic antidepressants (Amitriptyline, etc.), monoamine oxidase inhibitors (Iproniazid, Selegiline, etc.) and sympathomimetics (Adrenaline, Oxymetazoline, Xylometazoline, etc.).

When taken with neuroleptics (Aminazine, Phenothiazine, etc.), the likelihood of extrapyramidal disorders increases.

Cerucal causes inactivation of vitamin B 1, so they should not be used simultaneously.

Overdose

An overdose is manifested by the following symptoms:

• confusion;
• Anxiety;
• Extrapyramidal disorders;
• Increase in blood pressure.

With a mild overdose, all symptoms disappear on their own within a day after discontinuation of the drug without any treatment. In more severe poisoning, it is necessary to wash the stomach, give the person sodium sulfate and carry out symptomatic treatment aimed at stopping painful manifestations. At the same time, extrapyramidal disorders are usually eliminated by Bipereden, and anxiety is relieved by Diazepam.

Cerucal for children

General provisions

Cerucal is a drug that is quite often used to stop vomiting in children, including those under 2 years old, although this is prohibited. Despite the contraindication to the use of Cerucal in tablets for children under 14 years of age, it is actively used to stop vomiting. Since children, as a rule, do not suffer from other diseases of the gastrointestinal tract, the only purpose of using Cerucal is to stop vomiting.

Year after year, women share information with each other about how they gave their children Cerucal when they vomited, advising them not to pay attention to the ban on the use indicated in the instructions, since, according to their observations, nothing bad happened to the child. Of course, women are willing to help each other by sharing their life experiences and own observations, but in this case they are not entirely correct.

The fact is that vomiting in a child under 2 years old is a signal to call an ambulance. And for a child over 2 years old, to stop vomiting, you need to give Cerucal not in tablets, but buy a solution and inject it intramuscularly. Such use of the drug will be correct and safe, since the solution allows you to accurately dose Cerucal, minimizing the risk of overdose.

Cerucal (injections, tablets) - instructions for use for children

Tablets can only be given to children over 14 years of age half an hour before meals. In this case, a single dosage of the drug for stopping vomiting, nausea or hiccups is 0.5 - 1 tablet. The maximum allowable daily dosage for children aged 14-18 is 3 tablets. When vomiting, the drug is taken 2-3 times a day as needed. And as part of the complex treatment of diseases of the digestive tract associated with impaired motility of the stomach and intestines (gastritis, peptic ulcer, reflux esophagitis), Cerucal should be taken 0.5 - 1 tablet 2 - 3 times a day for 6 weeks - 6 months.

Cerucal injections in children should be used as emergency remedy for the relief of vomiting, nausea or hiccups of any origin. At the same time, children 14-18 years old are administered 1 ampoule of the solution 1-3 times a day, and the dosage for babies 2-14 years old is calculated individually according to body weight.

Cerucal for children - dosage for various diseases

The dosage of tablets and Cerucal solution is the same for all diseases in which the use of the drug is indicated, and is 0.5 - 1 tablet 2 - 3 times a day, or 1 ampoule 1 - 3 times a day for children 14 - 18 years old.

For children 2-14 years old, only Cerucal solution is used, the dosage of which is calculated individually according to body weight, based on the ratio: 0.1 mg per 1 kg of weight. That is, for a child weighing 10 kg, a single dose of Cerucal is 0.1 * 10 = 1 mg, which corresponds to 0.2 ml of solution. If necessary, the dosage can be increased to 0.5 mg per 1 kg of body weight. The maximum daily dosage of the solution for children weighing less than 20 kg is 10 mg (2 ml of solution), 20-30 kg - 15 mg (3 ml of solution) and 30-50 kg - 25 mg (5 ml of solution).

For children over 6 years old, you can use the following average dosages:

• Children 6-10 years old - administer 2.5 mg (0.5 ml of solution) 1-3 times a day;
• Children 10-14 years old - administer 5 mg (1 ml of solution) 1-3 times a day.

Use during pregnancy and breastfeeding

During the first trimester

annotation

Cerucal (in Latin - Cerucal) is a drug that most have not only heard of, but which is used by many for vomiting and nausea. It is prescribed by most doctors as an antiemetic and choleretic agent.

Also, the drug is actively used in veterinary medicine for dogs and cats after taking medication or before x-ray studies.

The release form is represented by tablets, or a solution for injection.

Pharmacological group - drugs used for problems of the gastrointestinal tract (gastrointestinal tract) - antiemetic.

From what cerucal, indications for use

The mechanism of action is due to the blocking of dopamine receptors responsible for the transmission of impulses from the stomach to the vomiting center, thereby preventing relaxation of the muscles of the stomach.

This medicine helps well in the fight against vomiting, nausea, hiccups, to normalize the state of the gastrointestinal tract, it simplifies the passage of food through small intestine thereby accelerating the process of gastric emptying.

Cerucal can be prescribed to a child as part of the treatment of postoperative nausea and vomiting, or after a course of chemotherapy.

Composition, how much

One ampoule (2 ml) contains:

• active ingredient: metoclopramide hydrochloride in the form of metoclopramide hydrochloride monohydrate - 10 mg;
• excipients: water for injection, sodium sulfite, sodium chloride, disodium edetate.

The cost of a package of 10 ampoules in Russia is about 250 rubles, in Ukraine - 250 hryvnias

One tablet includes:

• metoclopramide hydrochloride monohydrate at a dosage of 10.54 mg;
• additional substances: potato starch, silicon dioxide, lactose monohydrate, gelatin.

The average price for a pack of 50 tablets is 130 rubles in Russia and 150 hryvnias in Ukraine.

Analogues

Among the drugs that are interchangeable in terms of their effect on the body, the following can be noted:
1. Ganaton
2. Ceruglan
3. Motilium
4. Metamol
5. Apo-Metoclops
6. Raglan.

All submitted similar preparations contain one or more of the same active ingredients. A more detailed description and photo of them is presented on the Wikipedia website or in the reference book. medicines"Vidal". To decide what is best for you, consult with experts.

Instructions for use Cerucal tablets

Before drinking Cerucal, you should definitely consult a doctor. The medication should be taken 30 minutes before meals, preferably by prescription.

• Adults take 1 tablet 3-4 times daily.
• Dose for adolescents (from 14 to 18 years old) - half or a whole tablet 2-3 times a day.
• Maximum allowable dose at one time - 20 mg (2 tablets), per day - 60 mg (6 tablets).

During early pregnancy, with toxicosis

For pregnant women, admission is limited. In the first trimester, taking the drug is contraindicated, in the second and third - with caution, since Cerucal can affect the development of the fetus. Despite toxicosis, the use of cerucal on early dates pregnancy.

At breastfeeding and lactation, the reception of cerucal should be completely excluded.

Children with vomiting dosage

For children from 3 to 14 years old, the administration of the drug is often prescribed in one of the ways: intramuscularly or intravenously. Daily dosage the active substance should not exceed 0.5 mg per 1 kg of the child's weight, for one injection - 0.1 mg / kg (according to the manufacturer's information).

Cerucal instructions for use injections intramuscularly

For adults and children over 14 years of age, it is worth injecting the drug one ampoule (i.e. 10 mg of metoclopramide) at a time no more than 4 times a day.

The injection is carried out both intramuscularly and intravenously.

With pancreatitis

With pancreatitis, stagnation of food in the stomach often occurs. Cerucal is prescribed to speed up its passage. Additionally, it improves the flow of bile, thereby eliminating one of the causes of pancreatitis.

How old can you give?

Cerucal in the form of tablets is prescribed from 14 years and older. Children from three to fourteen are prescribed shots this drug. Up to three years, the medicine is contraindicated.

Vomiting is natural reaction organism for admission harmful substances or pathogenic microorganisms . With the help of the gag reflex, the body cleanses itself. But sometimes vomiting becomes uncontrollable and can lead to dehydration. This condition is dangerous for people of any age, but small children who are underweight are especially affected. With severe vomiting, doctors prescribe various antiemetic drugs, one of them is cerucal. Instructions for the use of cerucal for vomiting for children prescribe that it is allowed to be used even in children from 2 years old, but only as directed by a pediatrician or infectious disease specialist.

Why does vomiting occur in children

Vomiting in children is different reasons. But in any case, the baby needs to be helped quickly to prevent dehydration. The main causes of vomiting can be identified as follows:

• Poisoning by poor-quality food, drugs or other toxic substances.
• Diseases of the gastrointestinal tract of an infectious nature.
• Congenital developmental anomalies digestive organs or chronic diseases stomach and intestines.
• Weakness of the vestibular apparatus, which is accompanied by severe motion sickness in any transport.
• Binge eating.
• Excessive nervous tension.

Vomiting can also be triggered by an allergy to a particular food product.. Basically, this condition is first manifested by hiccups and skin rashes, and then vomiting is added.

General characteristics of the drug

Cerucal is a common antiemetic drug that can be used for nausea and vomiting in children. The active ingredient is metoclopramide. The drug enhances the motility of the digestive organs and stops the supply of signals between the nerve endings of the stomach and intestines to the brain, which is considered the center that activates the gag reflex. It is thanks to this that signals about indigestion do not reach the brain and nausea and vomiting do not occur.

The pharmaceutical industry produces cerucal tablets for nausea and an injection solution. It is impossible to self-medicate, since the drug has many side effects, and the dosage can be chosen incorrectly. A drug is prescribed for disorders of the digestive system, which are manifested by profuse vomiting.

Diseases in children that are accompanied severe vomiting, in a matter of hours lead to severe dehydration. In such cases, the only way out is cerucal, which is desirable to use under the supervision of a doctor.

At what dose is cerucal given to children

The dosage of the drug is calculated based on the body weight of the child and the severity of the condition.. In exceptional cases, the dose may be slightly increased, but this decision is made only by the attending physician:

• Children from 2 to 14 years of age are prescribed a drug at a dosage of 0.1 mg of the active substance per 1 kg of body weight, but at the same time daily rate should not be more than 0.5 mg of metoclopramide per 1 kg of body weight. If the patient has chronic kidney disease, then the volume of the drug is calculated by the doctor on an individual basis.
• Children over 14 years of age are allowed to increase the dose of the drug to 10 mg, drink Cerucal 3 times a day. Tablets are drunk 30 minutes before meals with plenty of clean water. The full course of therapy is often up to one and a half months. The doctor can adjust the course of treatment based on these tests and the general condition of the child.

Cerucal in ampoules for children with vomiting is prescribed in cases where vomiting, nausea or hiccups need to be stopped quickly. Injections for nausea and vomiting are given to adolescents from 14-18 years old intramuscularly, at the rate of 1 ampoule up to three times a day. The dosage for injections for a child under 14 years of age is calculated by the doctor, based on the weight of the small patient.

Cerucal in open ampoules is not subject to storage. They are opened immediately before use, while observing all the rules of antiseptics. The drug package is stored in a cool, dark place that is inaccessible to children.

Indications for the use of the drug

Cerucal acts on the motility of the digestive organs, therefore it is prescribed for any disorders that are accompanied by persistent nausea and vomiting. It is indicated for such diseases and conditions:

1. At severe nausea and indomitable vomiting, in addition to cases when such a condition is associated with weakness of the vestibular apparatus.
2. In violation of the motility of the gastrointestinal tract, for example, with dyskinesia of the bile ducts.
3. With paresis of the stomach due to diabetes.
4. In preparation for diagnostic manipulations on the digestive organs.

Besides, cerucal is prescribed in tablets to children with vomiting, when it is impossible to stop it in other ways. This drug is usually used in a medical institution, but according to the doctor's indications, therapy at home is also possible if the child is older than 7 years.

Contraindications for use and side effects

In young children and adolescents, the intake of cerucal is limited by a number of contraindications, which must be taken into account when choosing a drug. These include such diseases:

• benign and malignant tumors, which produce adrenaline in large volumes;
• chronic and acute illnesses intestines, including obstruction;
• prolactin-dependent tumors;
• history of epilepsy;
• congenital anomalies in the structure of the intestine and duodenum;
• suspicion of bleeding in the digestive organs;
• individual intolerance to the substances that make up the drug;
• convulsions and nervous tics of the face;
• children under 2 years of age.

V special occasions Cerucal is also prescribed for children under 2 years of age, after weighing all the risks. In this case, the attending physician calculates the dosage based on age, weight and general state sick child.

Cerucal has a lot of side effects that do not depend on the form of the drug. The most common health changes are:

• From the nervous system may be increased fatigue, dizziness and tinnitus. Also frequent complaints about nervous tick in children, which occurs when taking the drug.
• On the part of the blood supply system, changes occur in the composition of the blood - the level of granulocytes, an important component of leukocytes, decreases.
• On the part of the digestive system, there may be constipation or, conversely, diarrhea, as well as severe dryness oral mucosa.
• From the side of cardio-vascular system possible jumps blood pressure and increased heart rate.
• From the side endocrine system breast enlargement in boys and cycle failure in adolescent girls are possible.
• From the side immune system could be an allergy skin rashes and asthma attacks.

If, while taking the drug, there are any side effects, they stop drinking it and turn to the attending physician for an adjustment in treatment.

How to take Cerucal for poisoning

If a child has been poisoned by low-quality food or medicines, then through vomiting the body is cleansed and recovery occurs faster. In such cases, antiemetics should not be given immediately after the first bout of vomiting., this will slow down the output toxic substances naturally. The child first needs to be given first aid, which will be aimed at the rapid removal of toxic substances from the body. Protocol emergency care such:

1. The child is thoroughly washed stomach with a large volume of water. Can be taken clean water or with the addition of potassium permanganate. Potassium permanganate is pre-dissolved in a small volume of water, and only then added to the total volume of water for washing.
2. Give any adsorbents in a therapeutic dose. If used Activated carbon, then it is pre-crushed into powder and diluted in a small amount of water, and then only given to the child.
3. They make a cleansing enema, for which they take slightly salted water or a decoction of chamomile.

If all these measures did not help stop vomiting, then the use of antiemetic drugs, for example, cerucal, is indicated. Cerucal in case of poisoning can be drunk only after consulting a doctor.

Cerucal injections for vomiting are prescribed only in severe cases, when a child cannot take pills due to vomiting. It is forbidden to prescribe and make injections on your own, as this can lead to an overdose and serious consequences.

drug overdose

Cerucal overdose can be in the case of self-medication or an incorrectly calculated dose, when the doctor determines the weight of a small patient by eye. Another cause of overdose is improper storage of medicines when they are stored in a place accessible to children. If the child has taken too many cerucal tablets, then it is urgent to call a doctor or take the baby to the hospital on its own.

Symptoms of an overdose are quite specific, they can be distinguished by the following points:

• there is atypical drowsiness, confused consciousness;
• there is increased excitability and motor activity, which then develops into convulsions;
• the work of the heart is disturbed, which is manifested by instability of blood pressure, rapid heartbeat and high pulse.

If extrapyramidal disorders are observed during an overdose, then slow intravenous administration of an antidote is indicated, which is biperiden. In this case, the child must be under the constant supervision of doctors, until all signs of an overdose disappear completely.

How to prevent an overdose

To avoid cerucal poisoning, it is enough to follow a number of simple rules:

1. Do not self-medicate following the advice of relatives or neighbors. Any medications can only be taken if prescribed by a doctor..
2. Do not leave medicines in places accessible to children. All medicines should be stored in a special first-aid kit or box that is locked.
3. Cerucal in ampoules is prescribed only by a doctor. The medicine can be injected only after 6-8 hours, during this period of time the previous dose is almost completely excreted from the body.
4. Do not take an expired drug. The active substance in such medicines decomposes and forms toxic elements.

Even if a doctor prescribes cerucal for treatment, it is necessary to accurately inform him of the patient's weight. With a correctly calculated therapeutic dose, an overdose is excluded.

Medicine analogs

Instead of cerucal, the attending physician may prescribe other antiemetic drugs for children that have similar action. Despite the fact that cerucal is a highly effective antiemetic, it has a lot of contraindications and side effects, therefore, if possible, it is changed to other medicines:

• Motilium - great replacement cerucal, especially since it is allowed to prescribe to children from 1 year, and with the constant supervision of a pediatrician and from birth. Such a remedy for nausea and vomiting for babies is sold in the form of a suspension with pleasant taste which facilitates the treatment of babies. In addition, motilium helps to get rid of flatulence, belching and feelings of fullness in the abdomen. Sometimes it is prescribed to babies for intestinal colic;
• But-spasm - is prescribed for vomiting, which is caused by functional disorders. It could be gastroenteritis intracranial pressure or consequence radiotherapy. This medication can be given to children from the first days of life, but only under the supervision of a doctor and in accordance with the calculated dosage. But-spasm can be purchased as a syrup for babies and as a solution for older patients.

All analogs have their limitations and side effects. Before you start taking, you must carefully study the annotation.

What else can eliminate vomiting in a child

When vomiting is caused by typical food poisoning and the child's condition is satisfactory, then you can do without antiemetic drugs. Recipes can help in this case. traditional medicine. To stop vomiting attacks, children are given a decoction of peppermint or lemon balm.. To prepare decoction, you need to pour a tablespoon of crushed leaves with a glass of boiling water and insist in a thermos for about two hours. Then the broth is filtered and allowed to drink a tablespoon every half hour, until the condition returns to normal.

Drinking honey with lemon will not only replenish the fluid lost during vomiting, but also regulate the balance of electrolytes in the body. Such delicious drink has a tonic effect and quickly removes vomiting. Use it often, but in small portions.

Before trying to stop vomiting, you need to understand what caused it.. If this is poisoning with toxic substances, then you should not immediately take Cerucal, you need to wait until the body is a little cleansed of harmful substances.

On the one side pharmaceutical market our country is working at full capacity. On the other hand, you must always carefully read the recommendations that the manufacturer himself gives you. Despite the huge selection of medicines, a huge number of them contain elements harmful to our body or can cause severe side reactions. The same applies to drugs intended for children.

Today I invite you to discuss one of the possible means, which is prescribed for nausea and vomiting in a child - Cerucal. Let's find out what features the reception has this medicine and in general, is Cerucal possible for children.

Cerucal is available in two forms: tablets and ampoules for intramuscular / intravenous administration. Sold tablets of 50 pieces in a carton and each contains 10 mg of the active substance. The solution is sold in clear glass ampoules with a volume of 2 ml and also contain 10 mg of the active substance. The drug is produced in Croatia, but according to the technology and recipes of German scientists. Released this remedy on prescription.

Compound

Like all medicines, Cerucal consists of an active substance and an auxiliary. The first group includes - metoclopramide hydrochloride monohydrate. As for the second group, it all depends on the form of the drug. If this liquid solution in ampoules, then the composition contains such auxiliary components like sodium sulfite, sodium chloride, disodium edetate and water for injection.

If you choose tablets, then in this case the active substances of the drug are supplemented with such auxiliary ones as lactose monohydrate, potato starch, gelatin, silicon dioxide, magnesium stearate.

Operating principle

The main purpose of this drug is to stop vomiting or hiccups in a person. This happens due to the main component of the drug - metoclopramide. It blocks certain receptors in the stomach and duodenum responsible for sending signals to the brain. Thus, the physiological chain that causes the gag reflex is broken.

Indications

This medicine has enough wide range actions and can be assigned in a number of cases, for example:

• In the treatment of conditions that are associated with disorders motor activity alimentary tract. These include: irritable bowel syndrome, functional pyloric stenosis, heartburn.
• For nausea and vomiting various genesis. These include seizures that appeared as a result of disorders in the liver and kidneys, severe headaches, or as a result of taking certain medications.
• Diabetic intestinal paresis.
• In the process of preparing the patient for diagnostic studies of the digestive tract, to enhance the peristalsis of the gastrointestinal tract.

Often, Cerucal can be prescribed as an antiemetic during radiation therapy and with the use of cytostatic agents. However, the drug is practically ineffective in the treatment of vomiting attacks that are caused by vestibular and psychogenic causes. For example, a positive effect is rarely observed if you use the remedy for motion sickness syndrome.

At what age is it allowed to take

Since we are considering two forms of the drug, according to the instructions for use, it is not recommended to give Cerucal tablets to children under the age of 14. For the treatment of children younger age Cerucal can be prescribed in injections. The medicine is intended for intramuscular or intravenous administration and can be recommended for children from 2 years of age.

Side effects and contraindications

Despite their medicinal properties, this drug has a number of contraindications.

• Individual intolerance to the components of the drug. Especially careful is to be sick with bronchial asthma and other forms of allergies.
• Perforation of the gastrointestinal tract.
• Stenosis of the pylorus of the stomach.
• Epilepsy and seizures.
• Age up to 2 years for the drug in ampoules and up to 14 years for tablets.
• Gastrointestinal bleeding.

It is not recommended to take the medication during lactation, as it easily penetrates into breast milk. As far as pregnancy is concerned, this medicine is not allowed for use in the first trimester and is prescribed with extreme caution in the remaining 6 months.

In addition, there are a number of conditions and diseases in which the medication is taken with extreme caution. These include: liver dysfunction, bronchial asthma, arterial hypertension, intolerance to procainamide and procaine. The use of this drug can provoke the appearance of such adverse reactions:

On the part of the nervous system, the following may appear: headaches, insomnia, fatigue, anxiety, fear, depression, tinnitus, involuntary twitching of the muscles of the neck, face or shoulders, muscle hypertonicity. In especially severe cases, neuroleptic syndrome may develop.

From the hematopoietic and cardiovascular systems: agranulocytosis, hypotension, hypertension, supraventricular tachycardia. From the digestive system: diarrhea, dry mouth, constipation. On the part of the endocrine system in older patients: it is possible to enlarge the mammary glands in men and involuntary milk secretion and violation menstrual cycle among women.

It should be noted that the risk of adverse reaction increases in those patients who have problems with kidney function.

Cerucal for children instructions for use and dosage

Cerucal in ampoules dosage for children with vomiting and other diseases

Maximum possible daily dose for a child 2-14 years old is 0.5 mg of metoclopramide per 1 kg of body weight, in therapeutic purposes 0.1 mg of metoclopramide per 1 kg of body weight may be prescribed. Children over 14 years old (teenagers) are prescribed 3-4 times a day for 10 mg of metoclopramide, that is, 1 ampoule.

The drug can be administered intravenously and intramuscularly. It is recommended to administer the drug very slowly to reduce the risk of an adverse reaction. When preparing a small patient for examination, it is recommended to make 1-2 injections 10 minutes before the procedure.

Cerucal tablets dosage for children with vomiting and other diseases

Tablets are recommended to be taken 30 minutes before meals with plenty of water. For adolescents 14-18 years old, it is recommended to take the drug 2-3 times a day, 5-10 mg of metoclopramide. The course of treatment depends on the nature of the disease and is usually about 4-6 weeks.. The course of therapy in rare cases can be increased up to six months. In the process of treatment with this medication, it is necessary to refrain from work and activities that require an increased psychomotor reaction and increased attention.

To say unequivocally what will be better - pills or injections in one case or another - is quite problematic. It is very important to take into account the condition of the child, his age, etc. In some cases, with a strong and frequent gag reflex, it does not make sense to take pills, since the patient will return them back before the moment of absorption comes. In addition, the drug, administered intramuscularly or intravenously, starts to work many times faster, while tablets have a longer lasting effect.

Overdose

When you receive large doses than indicated in the instructions, patients may experience drowsiness, confusion, irritability, bradycardia, arterial hypotension or hypertension.

If you see symptoms of an overdose in a child, it is recommended immediate appeal to the doctor. In the future, the introduction of biperiden may be prescribed. In the future, it is necessary to monitor the condition of a small patient, and, if necessary, perform manipulations that will support vital important features organism.

Interaction with other drugs

• With the simultaneous administration of Cerucal and vitamin B1, a more rapid decay of the latter is observed.
• Metoclopramide, which is the active substance of Cerucal, changes the rate of absorption of other drugs. In addition, it accelerates the absorption of paracetamol, antibiotics and ethanol.
• The effectiveness of metoclopramide is reduced when it is taken concomitantly with anticholinergics.
• While taking the medicine, you can not drink alcohol, sedatives and antipsychotics.
• Cerucal is able to change the activity of tricyclic antidepressants, sympathomimetics and MAO inhibitors.

Analogues

Metoclopramide is prescribed for children over 6 years of age. Here, the active ingredient is also metoclopramide. The medicine is produced in two dosage forms: tablets and ampoules. For young children, intramuscular or intravenous administration is recommended. Older children are allowed to take medication in tablets.