What pills to lower blood pressure? Review of high blood pressure pills: drugs for the treatment of hypertension with minimal side effects

Hypertension often has a hidden course, hiding behind vague symptoms for years. However, all this time the disease constantly attacks target organs and destabilizes general condition body. The identified disease is subject to careful monitoring by specialists, as well as the patient himself. The effectiveness of prescribing long-acting medications has been proven, which are taken on a long-term basis and allow you to control hypertension and possible complications associated with it.

Prescribing blood pressure medications

The choice of drug therapy depends on the degree hypertension.

The assessment of the risk group into which the patient falls is based on examinations and examination of the medical history. And if tablets for grade 1 hypertension can be introduced gradually, after eliminating risk factors, then tablets for grade 2 and grade 3 hypertension can become a decisive link in saving health. For patients with such a life-threatening condition pharmaceutical treatment prescribed immediately, taking into account concomitant diseases.

The choice of drug therapy depends on the degree of hypertension

Classification of drugs

Among the large number of drug solutions existing on the market from arterial hypertension The following groups are distinguished:

  • Renin inhibitors.
  • Angiotensin 2 receptor antagonists.
  • Diuretics.
  • ACE inhibitors.
  • Alpha and beta blockers.
  • Blockers calcium channels.

Renin inhibitors

A group of such medications is used to stabilize blood pressure and protection of target organs.

The tone of the renin-angiotensin-aldosterone system (RAAS) depends on the activity of renin. Proven: high level renin increases the possibility cardiovascular complications hypertension. This hormonal system regulates blood pressure and blood volume in the human body. Renin inhibitors block its receptors and suppress the RAAS at the initial point of its activation.

Angiotensin 2 receptor antagonists

Most modern drugs in the treatment of hypertension. Medicines control the functioning of the RAAS through interaction with angiotensin receptors. Tone vascular system depends on their functioning. The active ingredients of these medications eliminate the cardiovascular effect of angiotensin 2 and its vasoconstrictor effect.

Renin inhibitors are used to stabilize blood pressure

Long-term use of drugs in this group allows for a pronounced antihypertensive and organoprotective effect. The effect develops smoothly; with constant use, the hypotensive effect is established after 2–4 weeks.

Diuretics

The use of diuretics is the traditional approach to lower blood pressure levels. Diuretics are most often combined with drugs from other groups when complex therapy. Diuretic medications remove excess fluid from the body, significantly reducing the load on blood vessels. Diuretics reduce the reabsorption of sodium ions in the kidneys, increasing the resistance of the vascular endothelium to a number of vasopressors (for example, adrenaline), which also leads to a decrease in blood pressure.

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ACE inhibitors (ACEIs)

Medicines included in this variety are the most widely used. Angiotensin-converting accelerator inhibitors (ACEIs) are designed to inhibit zinc ions at the point of conversion of angiotensin I to angiotensin II, which directly creates excess pressure in the blood vessels. These substances actually affect the decrease in RAAS activity both in the general bloodstream and at the level of organ tissue (kidneys, heart, brain).

ACE inhibitors serve as immediate help in case of a sudden jump in blood pressure; they quickly lower it to values ​​close to normal. The drugs protect and even restore the functions of the myocardium, blood vessels and kidney cells exposed to high blood pressure. The decrease in blood pressure when prescribing ACEI drugs occurs gradually, stabilization of pressure takes a couple of weeks.

ACE inhibitors are the most widely used

A (alpha) and β (beta) blockers

If it is necessary to quickly lower blood pressure, the choice is often made in favor of this type of drug. Alpha adrenergic receptors in the walls of blood vessels stimulate their narrowing under the influence of adrenaline. α-receptor blockers help cell resistance and provide wider vascular lumen and, as a result, a lasting decrease in blood pressure.

A-blockers serve as a restorative agent after a complication, such as a heart attack. The drug is also able to reduce the content of “bad” cholesterol and process and absorb glucose. β-blockers reduce the number of contractions of the heart muscle, directly affecting the normalization blood pressure. β-blockers are used in the treatment of atherosclerosis and a number of other diseases.

Medicines of this category can be used separately and combined with diuretics, calcium antagonists and a-blockers. Taking medications in this group must be strictly controlled, as there is a risk of withdrawal syndrome.

Calcium channel blockers

A group of the safest medications. The drugs prevent the flow of calcium ions into the heart muscle, which reduces its ability to contract. Calcium antagonists reduce tension in the smooth muscles of the arteries and expand the lumen inside the vessels. The heart rate also decreases. The drugs of this category are life-saving in case of hypertensive crisis. Calcium antagonists increase renal blood flow, which provides an additional diuretic effect.

Calcium channel blockers are the safest medications

Advanced drugs for long-term blood pressure control

Pharmaceuticals are constantly developing in search of optimal forms of drugs so that, with maximum availability of the active substance, the drugs do not increase the risk of side effects. Additionally, modern antihypertensive tablets for hypertension eliminate the consequences of the development of hypertension and serve as their prevention.

In general practice, tablets for hypertension are prescribed by a doctor, but the patient should independently collect information about optimal choice drugs and their main characteristics.

New generation hypertension pills list:

Losartan is a selective drug from the group of angiotensin 2 receptor antagonists.

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Action:

  • reduces blood pressure;
  • decrease in total peripheral vascular resistance;
  • reduction of adrenaline levels in the blood;
  • stabilization of blood pressure in the small circle;
  • diuretic effect;
  • prevention of the development of myocardial hypertrophy.

The drug is selected for the treatment of hypertension in combination with CHF. After a single dose, the pressure decreases as much as possible after six hours. A stable antihypertensive effect is created after about a month of administration.

Selective drug

Lisinopril is a well-known drug on the list of angiotensin-converting enzyme inhibitors. A mild drug for the treatment of I and II degrees of hypertension.

Action:

  • reduces blood pressure;
  • protects the heart muscle during left ventricular myocardial hypertrophy;
  • helps improve kidney function.

The therapeutic goal of administration is achieved in 2–4 weeks.

Renipril GT - the drug is a combined form of an ACE inhibitor and a diuretic. Reduces the appearance of angiotensin II and the secretion of aldosterone, eliminates its vasoconstrictive effect and helps to increase the patency of peripheral arteries.

Action:

  • decrease in blood pressure;
  • minimizing total peripheral vascular resistance;
  • improvement of blood circulation in the small circle;
  • reduction of tension in the kidneys.

Indicated when complex therapy is necessary.

Captopril is a popular drug from the group of ACE inhibitors. Effective for blood pressure control in grade 1 and 2 hypertension. Quickly lowers blood pressure if necessary.

Popular drug

Peculiarities:

  • Helps prevent heart failure.
  • It can be used as hypertensive therapy for patients with nephropathy and diabetes.

Arifon-retard (indapamide) is a diuretic, suitable for initial and maintenance therapy.

Action:

  • increasing the protective function and elasticity of the vascular endothelium;
  • preventing platelet aggregation.

With regular use, the therapeutic effect is observed after two weeks and reaches a maximum after two months. Used separately if there is a good response, or in combination.

Veroshpiron is a potassium-sparing diuretic. The hypotensive effect of the drug is based on its diuretic effect; The diuretic effect appears within a few days of treatment. While maintaining the level of potassium required by the body, the drug removes sodium ions and water. Used as part of combination therapy.

New generation of pharmacological agents for hypertensive patients

Practical medicine is gradually moving towards the perception of the body as a single whole, where each system and organ is in constant interaction and influence on each other. Therefore, a disease such as hypertension is also considered from the point of view integrated approach both in diagnosis and in drug therapy.

Veroshpiron - potassium-sparing diuretic

A modern antihypertensive drug no longer only reduces and stabilizes blood pressure levels.

The range of its tasks is much wider and anti-hypertension tablets perform the following functions:

  • protection of target organs from negative impact high blood pressure;
  • supporting the elasticity of blood vessels, their ability to contract and relax in response to external and internal stimuli;
  • restoration of the heart muscle during left ventricular hypertrophy;
  • improvement of renal excretory function;
  • increasing the stability of the central nervous system under stress;
  • maintaining human performance.

Article publication date: 11/10/2016

Article updated date: 12/06/2018

Almost every person after 45–55 years old suffers from increased blood pressure (abbreviated A/D). Unfortunately, hypertension cannot be completely cured, so hypertensive patients have to constantly take blood pressure pills for the rest of their lives in order to prevent hypertensive crises (attacks of high blood pressure - or hypertension), which are fraught with a host of consequences: from severe headaches to heart attack or stroke.

Monotherapy (taking one drug) gives a positive result only on initial stage diseases. A greater effect is achieved with the combined use of two or three drugs from different pharmacological groups, which must be taken regularly. It is worth considering that the body gets used to any antihypertensive pills over time and their effect weakens. Therefore, for lasting stabilization normal level A/D requires periodic replacement, which is carried out only by a doctor.

Hypertensive patients should know that medications that lower blood pressure come in rapid and prolonged (long-term) action. Drugs from different pharmaceutical groups have various mechanisms actions, i.e. To achieve an antihypertensive effect, they affect various processes in the body. Therefore, for different patients with arterial hypertension, the doctor may prescribe different means, for example, atenolol is better suited for one to normalize blood pressure, while for another it is undesirable to take it due to the fact that, along with the hypotensive effect, it reduces the heart rate.

In addition to directly reducing pressure (symptomatic), it is important to influence the cause of its increase: for example, treat atherosclerosis (if such a disease exists), prevent secondary diseases - heart attack, disorders cerebral circulation etc.

The table shows general list drugs from different pharmaceutical groups prescribed for hypertension:

Drugs prescribed for hypertension

These medications are indicated for the treatment of arterial hypertension (persistent high blood pressure) of any degree. Stage of disease, age, presence concomitant diseases, individual characteristics body are taken into account when choosing a remedy, selecting a dosage, frequency of administration and combination of drugs.

Tablets from the sartan group are currently considered the most promising and effective in the treatment of hypertension. Their therapeutic effect is due to blocking receptors for angiotensin II, a powerful vasoconstrictor substance that causes a persistent and rapid increase in A/D in the body. Long-term use of the tablets gives a good therapeutic effect without developing any undesirable consequences and withdrawal syndrome.

Important: only a cardiologist or local physician should prescribe medications for high blood pressure, as well as monitor the patient’s condition during therapy. On one's own decision made about starting to take some kind of hypertensive drug that helps a friend, neighbor or relative can lead to disastrous consequences.

Further in the article we'll talk about which drugs are most often prescribed for high pressure, about their effectiveness, possible side effects, as well as combination regimens. You will read a description of the most effective and popular drugs - Losartan, Lisinopril, Renipril GT, Captopril, Arifon-retard and Veroshpiron.

List of the most effective drugs for high blood pressure

Anti-hypertension pills with quick effect

List of rapid-acting antihypertensive drugs:

  • Furosemide,
  • Anaprilin,
  • Captopril,
  • Adelfan,
  • Enalapril.

Fast-acting drugs for hypertension

For high blood pressure, it is enough to put half or a whole tablet of Captopril or Adelfan under the tongue and dissolve. The pressure will drop in 10–30 minutes. But you should know that the effect of taking such drugs is short-lived. For example, a patient is forced to take Captopril up to 3 times a day, which is not always convenient.

The action of Furosemide, a loop diuretic, is the rapid occurrence of strong diuresis. Within an hour of taking 20–40 mg of the drug and for the next 3–6 hours, you will begin to urinate frequently. Blood pressure will decrease due to the removal of excess fluid, relaxation of vascular smooth muscles and a decrease in the volume of circulating blood.

Extended-release tablets for hypertension

List of long-acting antihypertensive drugs:

  • Metoprolol,
  • Diroton,
  • Losartan,
  • Cordaflex,
  • Prestarium,
  • Bisoprolol,
  • Propranolol.

Long-acting medications for hypertension

They have a prolonged therapeutic effect and are designed for ease of treatment. It is enough to take these medications only 1 or 2 times a day, which is very convenient, since maintenance therapy for hypertension is indicated continuously until the end of life.

These drugs are used for long-term combination therapy for grade 2–3 hypertension. Features of the reception include a long-term cumulative effect. To obtain lasting results, you need to take these drugs for 3 or more weeks, so you do not need to stop taking them if your blood pressure does not drop immediately.

Rating of tablets for high blood pressure with their descriptions

The list of antihypertensive drugs is compiled, starting from the most effective with a minimum of undesirable consequences to drugs with more frequent side effects. Although in this regard everything is individual, it is not in vain that antihypertensive therapy must be carefully selected and, if necessary, adjusted.

Losartan

A drug from the sartan group. The mechanism of action is to prevent the powerful vasoconstrictor effect of angiotensin II on the body. This highly active substance is obtained by transformation from renin produced by the kidneys. The medicine blocks receptors of the AT1 subtype, thereby preventing vasoconstriction.

Systolic and diastolic A/D decreases after the first oral administration of Losartan, at most after 6 hours. The effect lasts for a day, after which you need to take the next dose. Persistent stabilization of blood pressure should be expected after 3–6 weeks from the start of treatment. The drug is suitable for the treatment of hypertension in diabetics with diabetic nephropathy - damage to blood vessels, glomeruli, and kidney tubules due to metabolic disorders caused by diabetes.

What analogues does it have:

  • Blocktran,
  • Lozap,
  • Presartan,
  • Xartan,
  • Losartan Richter,
  • Cardomin-Sanovel,
  • Vasotens,
  • Lakea,
  • Renicard.

Valsartan, Eprosartan, Telmisartan are drugs from the same group, but Losartan and its analogues are more productive. Clinical experience showed its high effectiveness in eliminating elevated A/D even in patients with complicated arterial hypertension.

Lisinopril

Belongs to the group of ACE inhibitors. The antihypertensive effect is observed within 1 hour after taking the required dose, increases in the next 6 hours to a maximum and lasts for 24 hours. This is a drug with a long-term cumulative effect. Daily dosage– from 5 to 40 mg, taken 1 time per day in the morning. When treating hypertension, patients notice a decrease in blood pressure from the first days of taking it.

List of analogues:

  • Diroton,
  • Renipril,
  • Lipryl,
  • Lisinovel,
  • Dapril,
  • Lizacard,
  • Lisinoton,
  • Sinopril,
  • Lysigamma.

Renipril GT

This is an effective combination drug consisting of enalapril maleate and hydrochlorothiazide. In combination, these components have a more pronounced hypotensive effect than each individually. The pressure decreases gently and without loss of potassium by the body.

What are the analogues of the product:

  • Berlipril Plus,
  • Enalapril N,
  • Co-renitek,
  • Enalapril-Acri,
  • Enalapril NL,
  • Enap-N,
  • Enafarm-N.

Captopril

Perhaps the most common drug from the group of ACE inhibitors. Designed for emergency assistance for the purpose of stopping hypertensive crisis. It is not advisable for long-term treatment, especially in elderly people with atherosclerosis of cerebral vessels, since it can provoke sharp decline pressure with loss of consciousness. May be prescribed together with other hypertensive and nootropic drugs, but under the strict control of A/D.

List of analogues:

  • Kopoten,
  • Kaptopres,
  • Alkadil,
  • Katopil,
  • Blockordil,
  • Captopril AKOS,
  • Angiopril,
  • Reelcapton,
  • Kapofarm.

Arifon-retard (indopamid)

Diuretic and antihypertensive drug from the group of sulfonamide derivatives. In complex treatment therapy arterial hypertension used in minimal doses that do not have a pronounced diuretic effect, but stabilize blood pressure throughout the day. Therefore, when taking it, you should not expect an increase in diuresis; it is prescribed to lower blood pressure.

Pros Contraindications and special instructions
Ease of use (take once a day in the morning before meals) Prohibited for severe hypokalemia renal failure or serious liver dysfunction, allergies to the active ingredient of the drug
One of the most safe means from high blood pressure Not recommended for people with lactose intolerance
Harmless for people with endocrine disorders(for diabetes, obesity), because it does not affect the level of lipids and glucose in the blood
Has a minimum of side effects and is well tolerated by almost all patients
Reduces left ventricular hypertrophy
Affordable price
  • Indopamide,
  • Acripamide,
  • Perinid,
  • Indapamide-Verte,
  • Indap,
  • Acripamide retard.

Veroshpiron

Potassium-sparing diuretic. Take 1 to 4 times a day in courses. It has a pronounced diuretic effect, but does not remove potassium from the body, which is important for normal operation hearts. Used only in combination therapy for the treatment of arterial hypertension. If the dose prescribed by the doctor is followed, it does not cause side effects, with rare exceptions. Long-term treatment in high dosages (more than 100 mg/day) can lead to hormonal disorders in women and impotence in men.

Combination drugs for high blood pressure

To achieve maximum hypotensive effect and ease of administration, combination drugs have been developed, consisting of several optimally selected components. This:

  • Noliprel (indopamid + perindopril arginine).
  • Aritel plus (bisoprolol + hydrochlorothiazide).
  • Exforge (valsartan + amlodipine).
  • Renipril GT (enalapril maleate + hydrochlorothiazide).
  • Lorista N or Lozap plus (losartan + hydrochlorothiazide).
  • Tonorma (triamterene + hydrochlorothiazide).
  • Enap-N (hydrochlorothiazide + enalapril) and others.

Combination use of several drugs for high blood pressure

Combination therapy is the most effective in the treatment of arterial hypertension. The simultaneous use of 2-3 drugs, always from different pharmacological groups, helps to achieve lasting positive results.

How to take high blood pressure pills in combination:

Resume

High blood pressure tablets large number. With grade 2 and 3 hypertension, patients are forced to take medications constantly to keep their blood pressure normal. For this purpose, combination therapy is preferable, due to which a stable antihypertensive effect is achieved without hypertensive crises. Only a doctor should prescribe any blood pressure medication. Before making a choice, he will take into account all the features and nuances (age, presence of concomitant diseases, stage of hypertension, etc.) and only then select a combination of drugs.

An individual treatment regimen is drawn up for each patient, which he must adhere to and regularly monitor his A/D. If the prescribed treatment is insufficiently effective, you should contact your doctor again to adjust the dosage or replace the drug with another one. Taking medications on your own, relying on reviews from neighbors or friends, most often not only does not help, but also leads to the progression of hypertension and the development of complications.

Nausea, vomiting and other negative reactions appear. The likelihood of death due to cardiovascular pathologies increases significantly. To treat hypertension, pills are prescribed to lower blood pressure.

What is high blood pressure?

High blood pressure is considered to be a tonometer reading of 140/90 or higher in the population of different ages. In one case, doctors recommend changing lifestyle, reducing body weight, and applying a diet; in the other, doctors prescribe pills to lower blood pressure.

There are special patients who, in addition to hypertension, have diseases endocrine system, diagnosis of diabetes mellitus or cardiovascular pathology. Such people need constant medical supervision and well-designed combination therapy.

The appearance of hypertension is influenced by many factors, the main ones are:

  • Vascular tone. The more they spasm, the greater the pressure.
  • The amount of circulating blood. Large volumes of plasma in the vessels increase blood pressure.
  • Functioning of the cardiac organ.

Before prescribing medications, the doctor assesses the severity of the patient’s condition, the risk possible complications, takes into account age and the presence of other diseases. With hypertension, it is important not only to reduce blood pressure, but also to prevent its increase in the future. Stabilize throughout long period. Try to avoid hypertensive crises.

Medicines for normalizing blood pressure are divided by type, mode of action and effectiveness. Often used complex treatment using drugs from different groups.

Drug groups

Tablets to lower blood pressure are divided into several groups, depending on their antihypertensive mechanism of action, these are:

  • Beta blockers. Inhibits the activity of heart receptors. Reduce heart rate and force. Contraindicated in patients with COPD. Currently, selective beta-blockers are used, which are new generation drugs. Medicines in this group include Coriol, Metoprolol, Bisoprolol, Egilok, Tenorik.
  • Calcium antagonists. They block the channels that allow calcium to enter smooth muscle fibers and relax them. Reduce the strength and frequency of heart contraction. These are “Corinfar”, “Verapamil”, “Isoptin”, “Cinnarizine”, “Stamlo”.
  • Myotropic antispasmodics. They do not allow calcium to enter the cell. Used on early stage treatment of hypertension and muscle relaxation gastrointestinal tract(“No-shpa”, “Spazmalgon”, “Dibazol”, “Papaverine”, “Duspatalin”).
  • Nitrates. They are strong venodilators. They reduce the tone of blood vessels, increasing their lumen. Reduce blood flow to the heart. Can greatly reduce blood pressure and develop a number of adverse reactions(“Kardiket”, “Isoket”, “Perlinganite”, “Erinit”, “Nitrong”).
  • Alpha adrenergic blockers. Are considered strong antihypertensive drugs. They inhibit the activity of alpha-adrenergic receptors in arterioles, reducing spasms of the latter (Ebrantil, Arfonad, Benzohexonium, Phentolamine).
  • Sympatholytics. They neutralize the influence of the sympathetic nervous system, while destroying norepinephrine, which is responsible for impulses traveling along nerve fibers (Rauvazan, Isobarine, Reserpine).
  • Diuretics. Excess water is removed from the body, and along with it sodium ions (Furosemide, Triphas, Hypothiazide, Lasix, Aldactone).
  • Alpha stimulants. Activate alpha adrenergic receptors located in the brain. Reduce the activity of the remote sympathetic nervous system. Call side effects in the form of drowsiness, weakness and others (“Clonidine”, “Clonidine”, “Methyldopa”).
  • ACE inhibitors. They inhibit angiotensin-converting enzymes, preventing the formation of angiotensin-2 (Enalapril, Lisinopril, Tritace, Captopres, Renitec).
  • Sartans. Blocks the formation of angiotensin receptors in blood vessels. Reduces both upper and lower pressure. They have virtually no effect on the heart (“Cardosal”, “Lozal”, “Mikardis”, “Teveten”).

In the treatment of hypertension, complex therapy is used, where different types of drugs are used simultaneously.

Decrease in systolic pressure

Tablets for reduction upper pressure have a characteristic antihypertensive effect. They not only lower blood pressure, but also significantly reduce the risk of developing cardiovascular diseases.

Tablets to lower high blood pressure act as calcium channel blockers. Typically these are the following drugs:

  • "Amlodipine";
  • "Felodipine";
  • "Nifedipine".

When treating hypertension, diuretics such as Indapamide and Hydrochlorothiazide are added in small quantities.

Calcium channel blockers, used in combination therapy with diuretics, are among the main medications used to lower blood pressure in elderly patients. These medications also have a pronounced anti-atherosclerotic property.

Tablets to lower diastolic pressure

Patients should use tablets to lower blood pressure only as prescribed by a doctor. Usually if the lower pressure is increased long time, then the patient is placed in a hospital, where the necessary therapy is selected.

Typically, beta-blockers (Anaprilin) ​​are used to lower blood pressure, in addition to which ACE inhibitors (Captopril) are prescribed. Angiotensin receptor and calcium channel blockers are also used. In addition to the above remedies, diuretics may be prescribed.

Long-term and properly selected treatment of diastolic hypertension relieves stress from blood vessels and prevents negative consequences.

Fast-acting drugs

Rapid blood pressure lowering tablets are widely used to treat hypertension. The most common are:

  • "Nifedipine";
  • "Adelfan";
  • "Anaprilin";
  • "Enalapril";
  • "Captopril"
  • "Furosemide".

Many tablets to reduce pressure are placed under the tongue for resorption. For example, "Adelfana" or "Cartopril". Sublingual administration of the drug helps reduce blood pressure within 10-30 minutes. This result does not last long, which is why some medications have to be taken up to three times a day.

Tablets to quickly lower blood pressure are sometimes used in conjunction with diuretics, such as Furosemide. They remove excess fluid from the body, relax the muscles of blood vessels and reduce the amount of circulating blood.

Medicines with prolonged effect

Tablets for lowering blood pressure with a long-lasting effect are convenient to take (1-2 times a day). They are drunk continuously over a long period, up to 3-6 weeks. Such drugs include:

  • "Diroton";
  • "Metoprolol";
  • "Losartan";
  • "Prestarium";
  • "Cordaflex";
  • "Propranolol";
  • "Bisoprolol."

Here are some blood pressure lowering pills that have a long-lasting effect. These medications are used for grade 2-3 hypertension, when long-term treatment is required. The tablets have a cumulative effect and are not intended to quickly reduce blood pressure.

Combined products

Reducing high blood pressure (in this case, tablets should only be prescribed by a doctor and self-medication should be completely avoided) can be carried out with combination medications. For hypertension they give maximum result. An example of such medications is Noliprel, which combines the action of two active substances: perindopril arginine and indopamide. These drugs include Aritel Plus, active ingredients hydrochlorothiazide and bisoprolol, as well as Exforge tablets, which contain amlodipine and valsartan.
The following drugs act on the body in a similar way:

  • "Lorista N" (hydrochlorothiazide, losartan);
  • "Renipril GT" (hydrochlorothiazide, enalapril maleate).
  • "Lozap plus" (hydrochlorothiazide, losartan);
  • "Enap-N" (enalapril, hydrochlorothiazide);
  • "Tonorma" (hydrochlorothiazide, triamterene).

Since one tablet contains several active ingredients, such medications act on several factors that cause increased blood pressure. In some drugs, the active substances mutually neutralize negative effects.

As a rule, combination medications are taken once a day, regardless of meals. This makes treatment with them not only convenient, but also relatively cheap.

Combination therapy

Combined treatment gives best results with high blood pressure. Several drugs from different pharmacological groups are used here.

In the treatment of hypertension, a combination of a diuretic with a beta blocker, for example, Atenolol and Chlortalidonol, as well as Hydrochlorothiazide with Bisoprolol, is common. A diuretic is often combined with ACE inhibitors, these are Hydrochlorothiazide plus Captopril or Indopamide plus Perindopril tablets. For the treatment of hypertension, a combination of a diuretic and sartan can be used: “Hydrochlorothiazide” simultaneously with “Losartan” or “Hydrochlorothiazide” in combination with “Valsartan” pills.

IN therapeutic treatment In patients, a combination of a calcium channel blocker and a β-blocker (Felodipine and Metoprolol tablets) is used. Also in the treatment of hypertension, calcium antagonists and ACE inhibitors are combined (Amlodipine tablets plus the drug Benazepril or the drug Diltiazem in combination with Enalapril).

Effective tablets to lower blood pressure

There are many drugs aimed at treating hypertension, the most effective of which are:

"Losartan." The medicine belongs to the sartan group. Prevents the vasoconstrictive effect of angiotensin II on the body, which is formed due to the transformation of renin produced by the kidneys. The medication inhibits receptors of the AT1 subtype. Both upper and lower pressure begins to decrease after the first dose of the drug. When using the tablet for the first time, the effect lasts 6 hours, with long-term treatment - a day. To stabilize blood pressure, the medicine is taken regularly for 3 to 6 weeks. The drug gives lasting results and is well tolerated by patients.

"Lisinopril." It is an ACE inhibitor. The antihypertensive effect appears an hour after taking the drug. Helps keep blood pressure normal. Increases myocardial tolerance to excessive loads. In patients with severe hypertension, it prevents an increase in the myocardium and the volume of the chambers of the left ventricle. Suitable for people with heart failure and those who have had a heart attack.

"Renipril GT." Refers to combination drugs. Contains hydrochlorothiazide and enalapril maleate. The medicine lowers blood pressure gradually, without removing potassium from the body. Characterized by high efficiency. Well tolerated by patients. The maximum concentration in the blood is observed two hours after administration.

"Captopril." Belongs to ACE inhibitors. Tablets to lower blood pressure prevent a hypertensive crisis and act quickly. May be combined with other medications. They are not recommended for constant use, as they can sharply reduce blood pressure, which will lead to loss of consciousness. The drug improves blood supply to the heart muscle during ischemia and reduces platelet aggregation. Reduces myocardial hypertrophy. It is consumed up to 4 times a day. It has contraindications and may cause adverse reactions.

"Arifon-retard." Belongs to the group of sulfonamide derivatives. Combines the actions of a diuretic and an antihypertensive drug. Used in small doses. Does not have a pronounced diuretic effect. Within 24 hours, the blood pressure returns to normal. Used once a day. It is considered one of the safest drugs. It has a minimal number of negative effects and an affordable price.

"Veroshpiron". A diuretic that does not flush out potassium. Used in combination therapy and rarely causes negative reactions. Take tablets up to four times a day. When taken for a long time, the drug can cause hormonal imbalances in the body.

"Amlodipine." It is a calcium channel blocker. Has anti-ischemic and antihypertensive properties. Reduces vascular tone and gently lowers blood pressure. The maximum effect is observed after 8 hours. May cause a number of side effects.

"Clonidine." Belongs to the central alpha stimulants. Quickly lowers blood pressure, simultaneously removing feelings of anxiety, panic and fear. Pain relief. Prescribed for hypertensive crisis. When using it, you should regularly monitor your blood pressure.

"Enalapril." Refers to ACE inhibitors. The duration of action of the drug is one day. Therapeutic effect observed after a week of regular use. This good pills to reduce pressure. They suppress the formation of angiotensin 2 and its vasoconstrictor effect. Reduce systolic and diastolic pressure. Reduces the load on the myocardium. Suitable for patients with heart failure.

Which pills to choose to lower blood pressure should only be decided by a doctor, based on a complete picture of the disease.

Prevention of hypertension

It was written above about what pills there are to lower blood pressure. The doctor will tell you which ones are best to take, but now a little about how to prevent the occurrence of hypertension.

The main reasons causing an increase pressure are:

  • poor nutrition;
  • sedentary lifestyle;
  • extra pounds;
  • presence of bad habits (alcohol, smoking);
  • stress.

To avoid hypertension, you should give up bad habits, adjust your diet (the main part of the menu should be fresh vegetables and fruits), limit salt in the diet to 1.5 g per day, get enough sleep and spend time every day physical exercise. It is necessary to minimize the consumption of tonic drinks, and, if possible, completely abandon them. Periodically, to maintain health, take vitamin complexes with potassium, magnesium and vitamin C. Try to avoid stress.

Of course, it is important to choose good drug to reduce blood pressure, but it is better to prevent hypertension and ensure that it does not occur.

Today in pharmacies there is a large selection of drugs with antihypertensive properties. Figure it out and buy it yourself suitable drug impossible. The doctor will prescribe correct treatment and will prescribe fast-acting high blood pressure pills. Many people do not understand the complexity of the situation. When the arterial reading rises above 150/80 mmHg. Art. a person needs urgent help. If measures are not taken on time, the condition threatens to develop into a serious one, and there is a high risk of developing a stroke, heart attack or hypertensive crisis. It is important to know how to lower your blood pressure; quick-acting tablets will help normalize your tonometer level.

The list of drugs that can have a hypotensive effect in a short time is long, but you cannot take them at random; you must consult a doctor about this. Not only hypertensive patients have cases when they need to quickly bring down high blood pressure; similar conditions often occur in healthy people. There are several factors that provoke this pathology. Severe stress or excessive physical activity may increase blood pressure monitor readings.

Table of types of drugs

MedicinesActionDrug name
They prevent the synthesis of certain types of hormones that affect the tone of arterial walls, thereby reducing blood pressure."Captopril", "Enalapril", "Lizonopril" and others.
Slow down the absorption of calcium by cells located in the tissues of the arteries. As a result, the vessels relax, reducing the pressure of blood on their walls. You can relieve high blood pressure with the help of such drugs quite quickly."Nifedipen", "Verapamil" and others.
Beta blockersMedicines that reduce the rate of heart contractions. As a result of this process, the total volume of blood circulating in the arteries becomes smaller. Therefore, it is possible to quickly reduce blood pressure after taking medications of this group."Bisoprolol", "Anaprilin".
DiureticsIntensive removal of salt and chlorine from the body allows for a hypotensive effect. Only thiazide-type diuretics can cope with this task quickly. This medicine reduces blood pressure in a short time."Furosemide", "Hydrochlorothiazide".
SympatholyticsMedicines acting directly on the central nervous system. After administration, the area responsible for the movement of vascular walls is inhibited. Such drugs can quickly lower blood pressure."Clonidine", Clonidine."

Doctors often prescribe myotropic antispasmodics to patients, which help reduce tonometer readings in a short time. Taking such drugs leads to the expansion of the lumen of blood vessels, which reduces arterial level. Previously, doctors recommended medications such as alpha-blockers to patients, but today such drugs are not considered primary in the treatment of hypertension, as they increase the risk of stroke and heart attack. Before you quickly lower your blood pressure with pills, you need to take into account the fact that such methods can lead to serious consequences. A sharp decrease in tonometer readings can provoke loss of consciousness if the strength of blood flow becomes weaker.

The list of drugs representing the group of angiotensin-converting enzyme inhibitors is extensive. All such drugs are prescribed for hypertension, act on the body in a certain way and can quickly lower blood pressure. Despite the variety of such drugs, they have the same effect - blocking the production of a substance that promotes the synthesis of active angiotensin. This enzyme can cause persistent hypertension.

This group of medications has wide range possibilities, it affects many vital processes of the body, due to which the disease can be controlled.


Useful actions:

  1. improvement of kidney function;
  2. normalization of carbohydrate and lipid metabolism;
  3. increased blood circulation in coronary arteries, vessels of the renal department;
  4. does not have a negative effect on people with diabetes;
  5. provides rapid decline arterial level;
  6. reduces the likelihood of developing arrhythmia.

An important indicator is the possibility of prescribing such drugs to patients old age. Older people are already diagnosed with many pathologies of internal organs, which are not considered a contraindication to taking drugs from the ACE inhibitor group.

The mechanism of action of such tablets includes myocardial protection. Thus, the appearance of hypertrophy of the heart muscle is prevented, and if pathology is already observed, then after a course of treatment with these drugs you can expect reverse effect. In addition, these medications prevent the chambers of the heart from stretching, which is considered to prevent heart failure, as well as the development of progressive fibrosis.

Indications for use:

  • Symptomatic and essential hypertension.
  • When a regular increase in blood pressure is combined with diabetic nephrosclerosis, as well as diabetes mellitus of any type.
  • Hypertension caused by heart failure.
  • Kidney pathologies that provoke an increase in arterial parameters.
  • Some period after a stroke.
  • Acute myocardial infarction.
  • Heart failure, in which there is a reduced ejection of blood from the left ventricle.

It should be borne in mind that the course of therapy with such drugs should be long, only then can good results be achieved. therapeutic effect. There are contraindications that prohibit people from taking such pills.

When not to use:

  1. stenosis of the renal arteries on both sides;
  2. excessive amount of potassium in the body;
  3. severe renal failure;
  4. allergy to the components of the drug;
  5. childhood;
  6. hypotension.

Patients with hepatitis or cirrhosis, when an exacerbation period occurs, should refrain from taking medications from the ACE inhibitor group. The list of such tablets is large, but only a doctor will select the correct and safe form of the medication. If there is a need to quickly relieve pressure, then such drugs will help.

The list of medications for hypertension includes tablets of this group. Doctors have long established that often the cause of the development of such a disease is an imbalance of calcium in the blood plasma, as a result of which there is a need to take drugs that lower blood pressure. The tonometer readings in this condition can be very high, the person’s well-being becomes worse, and the risk of stroke and heart attack increases.

Calcium antagonists are a group of medications whose effects are based on inhibiting the penetration of calcium elements into the tissues of blood vessels and the heart. This substance takes part in the transmission of impulses from cells of the nervous system to intracellular receptors, which provokes contraction and tension. In patients with hypertension, there is usually always a decrease in the level of calcium in the cells, and an increase in the blood. Due to this pathological process, the body’s reaction to the action of hormones responsible for the tone of the arteries intensifies, the tonometer readings increase, and the person urgently needs to take pills for high blood pressure.


Indications for use:

  1. angina pectoris of a vasospastic nature;
  2. hypertension;
  3. angina pectoris;
  4. Raynaud's syndrome;
  5. tachycardia of supraventricular flow.

Such drugs are easily tolerated by patients, which makes them popular in the treatment of arterial hypertension. By including such tablets in a comprehensive course of treatment, doctors achieve the maximum effect of reducing the activity of the disease. This medicine reduces blood pressure in a short time, especially with long-term use.

When not to use:

  • aortic stenosis at critical moments;
  • weak sinus angle syndrome;

  • period of pregnancy and lactation;
  • some forms of heart failure;
  • certain disturbances in the functioning of the heart.

The drug should be prescribed only by a doctor. You cannot buy your own medicine at the pharmacy and drink it without your doctor’s permission. Before you quickly lower your blood pressure with any pills, you need to think about contraindications to taking them.

Beta blockers

These medications are a special group that help fight hypertension. The mechanism of action of these drugs is based on blocking adrenergic receptors, which are located in the arteries of the heart and blood vessels. These sensitive areas respond to the effects of norepinephrine and adrenaline, which provokes sharp jump arterial level. With this pathological process Many changes occur, which lead to an increase in tonometer readings. You need to take medications that quickly lower your blood pressure.

Indications for use:

  1. cardiomyopathy;
  2. myocardial infarction and a certain period after it;
  3. glaucoma;
  4. hypertension;
  5. thyrotoxicosis;
  6. cardiac arrhythmias of several types;
  7. chronic heart failure;
  8. angina pectoris.

The list of such drugs is large, but there are no serious differences in their composition and action; such tablets reduce blood pressure well and have virtually no side effects on the body. Beta blockers are prescribed to older people with caution.

When not to use:

  • bronchial asthma;
  • chronic obstructive pulmonary disease;
  • diabetes mellitus;
  • atherosclerosis obliterating course.

A course of therapy with beta-blockers together with calcium antagonists is not always possible. Eat certain rules joint use of such drugs. Reducing blood pressure occurs quickly if you know which pills to take first.

Diuretics

Among the medications included in the treatment of hypertension, diuretics are always present. With the help of such medications, people reduce their blood pressure to low levels when they are used incorrectly.
In the event of a sharp jump in arterial levels, you can take a Furosemide tablet, which will allow you to reduce the tonometer readings in the shortest possible period of time. You need to be careful with such drugs, as they have a rather strong effect on the body, and with regular use, calcium is removed from the body in large volumes, which is very dangerous.

By influencing the loop of Gentle, located in the kidneys, it provides a strong diuretic effect. Due to this action, such tablets reduce general level blood in the body, so diuretics are medications that lower blood pressure.

Indications for use:

  1. swelling of tissues that occurs for various reasons;
  2. heart failure stages 2 and 3;
  3. cirrhosis;
  4. hypertension;
  5. pulmonary and cerebral edema;
  6. cardiac asthma;
  7. hypercalcemia.

These drugs can have a large number of side effects, so you should take them with caution and in rare cases. There are also contraindications for use; you must carefully follow all the doctor’s recommendations.

When not to use:

  • chronic renal failure;
  • acute glomerulonephritis;
  • gout;
  • obstructive cardiomyopathy;
  • hypotension;
  • individual intolerance to the components of the product;
  • pancreatitis;
  • myocardial infarction in acute stage and others.

To lower your blood pressure quickly, you need to drink more safe medicines, since diuretics strong action harm the body and are used only in exceptional cases.

Sympatholytics

Drugs in this group reduce arterial levels quickly, but today they are used extremely rarely, only when severe course hypertension, when the tonometer readings rise sharply and high. Alpha brain stimulants affect the hemispheres of the organ, as a result of which the excitation of the central nervous system decreases. Some doctors suggest that long-term use of such medications contributes to the development of Alzheimer's disease.

Indications for use:

  1. arrhythmias;
  2. treatment of people with mental illnesses;
  3. open-angle glaucoma;
  4. arterial hypertension.


Usually, such tablets should not be taken as a course, but only in case of pressure surges, but in severe cases of hypertension, small doses of sympatholytics are sometimes prescribed, which are taken for a long time. Often these medications are prescribed in combination with other antihypertensive medications, often with diuretics.

When not to use:

The doctor will prescribe which drug of this group to choose, and without his prescription you will not be able to buy the drug at the pharmacy.

It should be noted that rapid action of medications can be achieved only if the tablet is not swallowed with water, but placed under the tongue. There are medications designed for this use. Often, the doctor prescribes taking several medications at once, most often these are diuretics and ACE inhibitors. There are drugs from the sartan group, they have earned popularity due to their effectiveness, but their effect is cumulative, so in emergency cases such drugs will not help.

A doctor's prescription for hypertension is always complex. Patients need to take several types of medications at once. You cannot adjust such therapy yourself; this can negatively affect your health.

Many people are concerned about how to reduce blood pressure, what pills have fast action. By using similar drugs the hypertensive patient’s condition returns to normal, but treatment must be complete and long-term for the disease to subside.

People who suffer from hypertension are constantly forced to large quantities take pills for high blood pressure. There are currently quite a lot of such medicines, as they say, for every taste and color. Your attending physician, and, we hope, our article will help you make your choice.

What pills to take for high blood pressure?

Advertising, which is now filled with the Internet and television, plays a big role in our choice of medicines. However, do not rush to run to the pharmacy for medicine, even if commercial you were promised a “guaranteed” effect. Even vitamin preparations It is not recommended to drink “just like that,” especially if we are talking about such serious medications as antihypertensives.

For every patient effective tablets for high blood pressure can be different, because the doctor prescribes treatment exclusively according to an individual program, depending on the patient’s age, his condition, duration, stage and form of the disease, and the presence of contraindications.

Do not self-medicate! This phrase is already quite hackneyed, but never loses its relevance: a pill that helps your neighbor can sometimes help you, but the consequences of this uncontrolled intake can be disastrous.

Instead of asking acquaintances and friends about good antihypertensive pills, it is better to inquire about a good doctor who you can safely trust with your health.

What kind of high blood pressure pills are there?

Tablets for high blood pressure can be divided into several groups, which imply different effects of drugs on the body, reaching in different ways one common goal: Reduce pressure. These are the following groups of medications:

  • medications that have a diuretic effect ( diuretics– indapamide, furosemide, polythiazide, lasix);
  • drugs that dilate blood vessels (hydralazine, minoxidil);
  • calcium antagonists (nifedipine, verapamil, diltiazem);
  • neurotropic drugs (clonidine, guanfacine, dopegit, rilmenidine);
  • medicines-ACE inhibitors (impairing the formation of active angiotensin - captopril, benazepril, enalapril, etc.);
  • agents that block angiotensin receptors (losartan, cozaar, etc.).

Only the doctor should decide which particular group of drugs to prescribe, what medications for high blood pressure, tablets or injections. Sometimes combination treatment can be used with the simultaneous administration of several drugs, including in different dosage forms.

Tablets for high lower pressure

Indicators of lower (it is called diastolic) pressure changes depending on resistance vascular wall. That is, lower pressure increases due to spasm or narrowing of blood vessels, which can be caused by swelling and fluid retention in the body.

Lower pressure is sometimes referred to as “cardiac”, since the reasons for its increase should often be sought in the work of the heart. Pathologies of the adrenal glands, endocrine system, and heart disease can also be causes. Prolonged high diastolic pressure has a detrimental effect on the heart muscle and coronary blood flow, so it is imperative to take measures to reduce the diastolic pressure.

Refusal to eat salt and preservatives is the first remedy in the fight against an increase in diastolic readings. It is recommended to undergo all necessary studies and tests to establish the real reason swelling and poor health.

If you have diastolic high blood pressure, treatment - tablets - should be aimed at removing excess fluid from the body, that is, have a diuretic effect. These drugs are hypothiazide, veroshpiron, triampur, indap, etc. Depending on the doctor’s recommendations, it is possible to use beta and calcium blockers, drugs such as metoprolol, verapamil, atenolol. Treatment can be carried out using folk remedies, herbal mixtures with a calming effect.

What to take for high blood pressure when pills don’t help?

Sometimes the development of the disease provokes such situations when the patient is faced with a choice: high blood pressure, what to take - pills or medicinal herbs?

Of course, treatment with folk remedies has its advantages, but advice from good doctor. We will give a few recipes that, judging by the reviews, cope well with the problems of high blood pressure:

  • Freshly squeezed helps a lot beet juice with the addition of natural honey, as well as juice and compote from viburnum, raspberries, and currants. You can use tea made from the fruits and leaves of plants;
  • Hawthorn flowers are poured with boiling water 1:10, left for half an hour and drunk a quarter glass before meals;
  • motherwort herb is poured with boiling water 2:10, you should drink one small sip three times a day before meals;
  • It is useful to eat honey mixed with garlic at night, sometimes the mixture is diluted in milk and drunk;
  • Kombucha - they say that its constant use normalizes blood pressure and cholesterol levels, relieves headaches and heart pain;
  • you can brew and drink tea from fresh or dry leaves of dark grapes;
  • white acacia color - take 1 spoon per glass of boiling water, infuse and drink half a glass before meals;
  • infusion of dill seeds - brew 2 teaspoons in a liter of boiling water, take half a glass three times a day;
  • cabbage pickle - rich in vitamins and microelements helps stabilize blood pressure.

For quick effect you can use diuretic herbs, such as birch leaves, lingonberry, burdock, as well as juniper, string, bearberry, horsetail. Treatment with plants can be carried out regularly and as a prevention of hypertension.

Rest, normal sleep, fresh air- all this will help in the fight against high blood pressure.

What tablets can be used to reduce high blood pressure?

How to reduce high blood pressure, there are different pills, so which ones to choose?

If it is not possible emergency treatment See your doctor, try using diuretics: their effect usually does not take long to appear. However, remember that it is not recommended to sharply reduce blood pressure; this should be done gradually, evenly reducing the load on the organs, including the heart.

Diuretic tablets for high blood pressure - list of the most common drugs:

  • hypothiazide, hydrochlorothiazide - require careful use when diabetes mellitus, no more than 25 mg per dose;
  • indap, indapamide, arifon, ravel – effective drugs mild action, they can be used regularly, they are also very convenient to take (take only one tablet per day);
  • furosemide, lasix - drugs not intended for continuous use, are used 1-2 times to relieve a hypertensive crisis;
  • diuver, britomar - not such a sharp effect as furosemide, but longer and more gentle.

And yet, how to reduce high blood pressure, use pills or other means? Self-medication is not best option in this situation, take the advice of a good doctor.

Constant advice about healthy way life, proper nutrition, fight against overweight, quitting smoking and drinking alcohol may seem hackneyed and boring to some. However, the application of these recommendations is much more effective than any existing tablets from high blood pressure.

The best pills for high blood pressure

The prescription of medications to lower blood pressure should be individualized, taking into account the characteristics of the individual patient. Patients aged 40-45 years and older usually take high blood pressure pills, the names of which are quite common. These drugs are adelfan, corinfar, captopril, capoten, cordaflex, capozide. These medications can be taken by patients who have previously experienced cases of high blood pressure.

If blood pressure rises for the first time, especially in young patients, as well as after suffering severe stress or strong psycho-emotional stress, it is recommended to take Andipal, which promotes the expansion of peripheral blood vessels and has a sedative effect.

Cumulative drugs are used for long-term therapy increase in pressure. These drugs are Diroton, Berlipril, Noliprel, Enap, Prestarium.

When cases of hypertension recur and even become more frequent, you should definitely consult a doctor. He will correctly adjust the treatment and select the optimal drug.

Kapoten

Capoten (aka captopril) is a pill for high blood pressure, reviews of which are mostly positive character. This medicine was synthesized back in the 70s, but has not yet lost its popularity. It is used for hypertension and cardiac ischemia.

Kapoten, like most antihypertensive drugs, requires regular use, and is also perfect for emergency assistance during a hypertensive crisis. The big advantage of the drug is its relatively low cost and the generally recognized effectiveness of the drug. The downside is the need to take pills frequently and constantly, up to 4 times a day, and not once, like most new generation drugs.

Capoten can be prescribed as a stand-alone drug, or in combination with other antihypertensive and nootropic drugs.

Kapoten normalizes the hypertrophied left ventricle, prevents the progression of cardiac failure, and promotes the development of positive dynamics in patients in a post-infarction state. The many advantages of the drug include its beneficial effect on the urinary system, in particular on the kidneys: capoten weakens the effect of high blood pressure on them and prevents the development of renal failure.

Typically, the drug is prescribed from a minimum dose of 6.25 mg up to three times a day, gradually increasing the dosage to 25 mg. Maximum permissible single dose medications – 50 mg. The treatment regimen with capoten is adjusted depending on the blood pressure readings, periodically monitoring it and comparing the indicators. The duration of action of the tablet is about four hours.

Andipal

Andipal are combined tablets for high heart pressure, which are used for severe vascular spasms. Such conditions develop as a result of vegetative-vascular disorders, as well as after severe stress.

The complex drug has vasodilating, analgesic, sedative properties and contains papaverine, dibazol, analgesic and phenobarbital. For long-term treatment this remedy is not used, since andipal is purely symptomatic remedy, which quite quickly gets rid of pain syndrome, has a calming effect on the nervous system, lowers blood pressure.

Maximum daily intake– 3 tablets, can be taken for no more than two days. If during this period your condition has not improved, you will have to consult a doctor for a diagnosis and prescription of more effective medications.

If you do not know for sure what your blood pressure is, it is not recommended to take the drug Andipal, since with low blood pressure the situation can only get worse.