Nurofen (tablets) - instructions, use, indications, contraindications, action, side effects, analogues, dosage, composition. The most effective and widely used painkiller in pharmacies is Nurofen.

Doctors know thousands of types of medicines. It is doctors who can choose the right and effective treatment. However, patients also want to know what is being prescribed to them and for what purposes. In this article we'll talk about the drug "Nurofen". What it treats - you will find out further. It is also worth giving instructions on how to use the product.

Composition and form of production of the medicine

Main active substance this tool is ibuprofen. In addition, the medicine contains additional components. However, their quantity and type depend on the form of release of the product.

Currently, a consumer can purchase several different types medicine "Nurofen". What they help with, you will find out further. The most common tablet form. These are ordinary hard pills and capsules containing liquid substance. The manufacturer also produces ointment and gel for external use. In addition, you can find products for children that come in the form of syrup and rectal suppositories.

What are the contraindications to using the drug?

You should not use tablets and syrups in case of exacerbations of gastrointestinal diseases. These include the following pathologies: ulcer, inflammation duodenum, gastritis and so on.

An absolute contraindication to treatment with this composition is pregnancy. However, in the first case, it is allowed to use the medicine in minimal dosages under the supervision of a doctor.

If there are problems with the heart, blood vessels, or the patient has high blood pressure, then the drug should not be used. For liver and kidney diseases, you should choose alternative remedy for correction.

Treatment with this drug is contraindicated if hypersensitivity to one of the components. Some forms of the medicine should not be used to treat children under six years of age.

What does Nurofen help with?

There are many indications for using this product. However, in all cases, the dosage and treatment regimen may vary greatly. Most often the composition is used to treat pain and fever. However, reasons to assign you this medicine the doctor may have more. Let's learn more about the drug "Nurofen". What can it cure?

When it's hot. Nurofen helps with fever quite quickly. At the same time, syrups and liquid form capsules are preferable, since their effect is faster.

An adult with a fever should take one capsule or drink about 15 milliliters of baby syrup. Within half an hour the effect of the treatment will be noticeable. For fever, Nurofen should be used for no more than three days. If after this you do not feel better, then you should see your doctor again and take some tests.

For flu and colds. Nurofen is a great remedy for the flu. The drug eliminates symptoms that become painful for the patient. These may include aching bones, throbbing temples and photophobia.

You can take Nurofen for colds for no more than three days. In this case, you are allowed to take up to 3-4 tablets per day. It is worth dividing the portion into equal parts and taking it at regular intervals. The drug is also an anti-inflammatory agent. That is why it not only has an antipyretic and analgesic effect, but also fights the source of infection.

For pain in bones and muscles. The drug in the form of a gel and ointment perfectly eliminates pain. It is used for after bruises. It is worth noting that before using the substance you must ensure that there is no fracture.

For athletes, Nurofen gel will help get rid of pain and discomfort associated with prolonged exercise. You need to apply the composition thin layer, gently rubbing into the skin. The drug begins to act almost instantly. The frequency of use of the gel can be up to 4 times a day with an interval of six hours. The course of treatment lasts from several days to two weeks. If after this period of time there is no improvement, then you should consult a doctor.

Periodic pain in women. The drug copes well with the drug. It is also widely used in postoperative period. During surgical interventions in the area of reproductive organs, women are prescribed a course of the drug in for preventive purposes. In this case, you need to take 1-2 tablets 2-4 times a day for five days.

Breastfeeding women can use the pediatric form of the drug. In this case, it is necessary to calculate the minimum dosage of the drug and take it.

Is it permissible to use the product in young children (under the age of six)

The product is actively used to treat children and children infancy. In this case, a suitable form must be used. You can choose candles or syrup. Both formulations are allowed from three months of age.

The drug relieves fever and pain. The product is widely used after vaccination for preventive purposes. The medicine "Nurofen" helps relieve pain in the gums during teething; it is also prescribed for otitis media and headaches. Remember that to treat children, you must first consult a specialist.

The drug "Nurofen": analogues

This remedy, like most drugs, has many analogues. Some of them are absolute and have not only same action, but also the composition. Others form a group of relative analogues and can only boast of a similar effect on the body.

The drug "Nurofen" has the following analogues: "Burana", "Ibuprofen", "Brufen" and others. Drugs similar in action include the drugs “Paracetamol”, “Cefekon”, “Nimulid”, “Nise” and so on.

How much does the product cost?

The price of the drug "Nurofen" differs depending on the form of release of the composition. Children's syrup costs about 200 rubles. have a price from 100 to 150 rubles.

Tablets with solid content will cost you about 120 rubles. Capsules with a liquid composition cost about 200 rubles. Gel for external use has a price range from 100 to 200 rubles.

Summing up

Now you know what the drug Nurofen helps with. Price for different shapes the drug will not be the same. In some cases, after using the product, you may experience adverse reaction, which most often manifests itself in the form of a skin rash, itching, nausea, and disruption of the digestive system. In this case, you should immediately stop using the composition and contact a specialist to correct the condition and select an alternative drug for treatment.

Use the drug as described in the instructions for use. Good health to you!

Thank you

Nurofen is a drug from the group of non-steroidal anti-inflammatory drugs(NSAID), which has analgesic, anti-inflammatory and antipyretic effects in various pathological conditions and diseases. Therefore, Nurofen is used as a symptomatic remedy in complex therapy various diseases accompanied by pain, inflammation in tissues and increased body temperature. Thus, Nurofen is used to eliminate painful symptoms (pain, fever and inflammation) for influenza, acute respiratory infections, acute respiratory viral infections, headaches, dental, muscle, joint and menstrual pain, severe pain in the throat, neuralgia, migraines, as well as in case of damage to ligaments, muscles and sports injuries.

Types, names and forms of release of Nurofen

Currently Nurofen is available in the following varieties:

Nurofen;
Nurofen Active;
Nurofen for children (children);
Nurofen Period;
Nurofen Plus;
Nurofen Plus N;
Nurofen Ultracap;
Nurofen Ultracap Forte;
Nurofen Forte;
Nurofen Express;
Nurofen Express Neo.

All of the listed varieties of Nurofen are commercial versions of the same drug with exactly the same therapeutic effects, indications for use and rules of use. The only difference between the listed varieties of Nurofen is that they can be produced in different dosage forms and dosages that will allow you to choose best option for each specific situation. For example, to eliminate dental or menstrual pain, any type of Nurofen in the form of tablets or capsules for oral administration is suitable. If the pain is severe, then you can choose the type of Nurofen tablets or capsules that contains more active substance, for example, Nurofen Forte.

Varieties of Nurofen are available in the following dosage forms:

Nurofen - tablets for oral administration, effervescent tablets for solution and gel for external application;
Nurofen Active – lozenges;
Nurofen for children – oral suspension and rectal suppositories;
Nurofen Period - extended-release tablets;
Nurofen Plus and Nurofen Plus N – film-coated tablets;
Nurofen Ultracap and Ultracap Forte – capsules for oral administration;
Nurofen Forte – tablets;
Nurofen Express – capsules and tablets;
Nurofen Express Neo are sugar-coated tablets.

Different varieties of Nurofen are usually called simply "Nurofen" and the dosage form is added, for example, tablets, capsules, suspension, etc. Children's Nurofen is often called simply a syrup or suspension, because this form used only for the treatment of children.

Nurofen - composition

The composition of all varieties of Nurofen as active component includes ibuprofen in various dosages. Ibuprofen in an amount of 200 mg is contained in the following dosage forms and varieties of Nurofen:

Tablets for oral administration and effervescent tablets for the preparation of Nurofen solution;
Nurofen Active tablets;
Tablets Nurofen Plus and Plus N;
Nurofen Ultracap capsules;
Tablets Nurofen Express and Express Neo.

However, Nurofen Plus and Nurofen Plus N, in addition to 200 mg of ibuprofen, also contain 10 mg of codeine per tablet, which enhances the analgesic effect of the drugs. Thus, the most powerful painkillers are Nurofen Plus and Nurofen Plus N.

Other varieties and formulations of Nurofen contain ibuprofen in the following dosages:

Nurofen gel for external application – 5% (5 g of ibuprofen per 100 g of finished product);
Nurofen for children - suppositories 60 mg per suppository and 100 mg per dose of suspension (100 mg per 5 ml);
Nurofen Period – 300 mg of ibuprofen per extended-release tablet;
Nurofen Forte – 400 mg per tablet;
Nurofen Ultracap Forte – 400 mg per capsule.

As you can see, there are varieties of Nurofen with different dosages of the active substance, which allows a differentiated approach to the selection of a specific drug for each case.

Therapeutic effect

Nurofen has anti-inflammatory, antipyretic and analgesic effects. Moreover, these effects develop locally if the drug is applied topically in the form of applying a gel to areas skin. In this case, the area of skin and tissue underneath that was treated with Nurofen gel is anesthetized, the inflammatory process and the feeling of heat are stopped. If Nurofen is taken orally or administered rectally in the form of suppositories, then its effects are realized in all organs and tissues in which there is an inflammatory process or pain. When taking the drug orally, there is also a decrease in general temperature bodies.

All these effects of Nurofen are provided by its ability to block the enzyme cyclooxygenase-2 , which catalyzes the formation of special substances - prostaglandins . Prostaglandins, in turn, are substances that cause pain, inflammation in tissues, as well as an increase in overall body temperature or a local sensation of heat in the area of injury. That is, Nurofen simply stops the synthesis biologically active substances, which cause pain, inflammation and fever, thereby eliminating these symptoms.

Nurofen - indications for use

Indications for use for all varieties of Nurofen various dosages, intended for oral administration, are exactly the same. That is, all capsules and tablets, regardless of dosage, have the same indications for use. The indications for use only for the gel for external application are somewhat different.

So, all forms of Nurofen for oral administration indicated for use for the relief of pain, fever and inflammation in the presence of the following diseases or conditions:

Arthritis of various types, accompanied by pain and inflammation of the joints (rheumatoid arthritis, psoriatic arthritis, osteochondrosis, arthritis with systemic lupus erythematosus);
Neuralgic amyotrophy;
Ankylosing spondylitis (Bechterew's disease);
Pain syndrome any localization, regardless of causative factor(dental, head, menstrual pain, pain in muscles, bones and joints, radiculitis, migraine, bursitis, tendonitis, tendovaginitis, etc.);
Pain after surgery or injury;
Pain due to malignant tumors;
Painful menstruation;
Pain due to the inflammatory process in the pelvis (for example, adnexitis, endometritis, etc.);
Pain during childbirth;
As a suppressant drug contractile activity uterus under threat premature birth;
Temperatures at infectious diseases or a cold.

It should be remembered that Nurofen is indicated only for symptomatic therapy to reduce pain and inflammation, but it does not affect the cure or improvement of the disease. Therefore, in addition to Nurofen, specialized medications are needed for treatment.

Gel Nurofen shown for local application for the following conditions or diseases:

Muscle pain;
Arthritis;
Ligament damage;
Injuries while playing sports;
Neuralgia.

It should be remembered that Nurofen gel is applied locally to the skin and relieves pain and inflammation in this area, but does not directly treat the disease. Therefore, Nurofen gel is only symptomatic drug, which can be used in combination with other medications whose action is aimed at curing pathology or changing its course.

Nurofen for children - indications for use

Nurofen syrup and suppositories (suppositories) for children have the following identical indications for use:
1. As antipyretic at various diseases accompanied by an increase in temperature, such as:

Flu;
Childhood infections;
Reactions to vaccination.

2. As an anesthetic for the following types pain syndrome:

Headache;
Toothache;
Migraine;
Neuralgia;
Pain after injuries to muscles, tendons, joints, ligaments and bones.

Instructions for use

Let's consider the rules for the use and dosage of Nurofen in three subsections concerning forms for oral administration (tablets and capsules), gel for external use and children's suppositories, and suspension.

Nurofen tablets and capsules - instructions for use

Tablets and capsules must be taken orally after meals. If you take the drug before meals, it may cause discomfort in the stomach. Capsules and coated tablets must be swallowed whole, without biting, chewing or crushing in other ways, but with a small amount of water. Effervescent tablets must first be dissolved in half a glass of water, and then drink the resulting solution for 10 - 15 minutes.

If pain, inflammation or fever does not go away within 2 to 3 days from starting Nurofen, you should stop taking the drug and consult a doctor immediately. It is also necessary to stop taking Nurofen and consult a doctor if side effects occur.

If it is necessary to take medications containing steroid hormones, Nurofen should be discontinued two days before. In addition, during the entire period of taking Nurofen, you must refrain from drinking alcohol.

During the entire period of Nurofen therapy, it is necessary to regularly, at least once every 1-2 weeks, take a general and biochemical blood test to determine the activity of liver enzymes (AST, ALT), as well as the concentration of urea and creatinine. If deviations from the norm occur, you must stop taking the drug and consult a doctor. Also, during the entire course of therapy with Nurofen, it is necessary to monitor the condition of the stomach, since the drug can provoke gastropathy. If gastropathy (unpleasant stomach symptoms) is suspected, it is necessary to undergo an examination, based on the results of which the doctor will decide whether to continue or suspend therapy.

The dosage and duration of taking Nurofen depend on the disease for which the drug is taken to eliminate the symptoms.

To relieve dental, menstrual, muscle, traumatic and other intermittent pain, adults and children over 12 years of age should take Nurofen tablets or capsules 200 mg 3 to 4 times a day. In order to obtain the fastest effect, Nurofen can be taken 400 mg 3 times a day. Extended-release tablets (Nurofen Period) should be taken 300 mg twice a day. Children from 6 to 12 years old can be given Nurofen 200 mg no more than 4 times a day. That is, the maximum permissible dosage for children 6–12 years old is 800 mg. In addition, it must be remembered that “adult” varieties of Nurofen can only be given to children whose body weight is more than 20 kg. Children weighing less than 20 kg should only be given children's Nurofen.

Interval between doses regular tablets and capsules must be at least 6 hours, and extended-release tablets must be at least 12 hours. Maximum daily dosage Nurofen in tablets and capsules is no more than 1200 mg (1.2 g).

For severe chronic diseases accompanied by pain and inflammation, Nurofen must be taken long-term in the following dosages:

Osteoarthritis, arthritis, ankylosing spondylitis - take 400 - 600 mg 3 - 4 times a day.
Rheumatoid arthritis - take 800 mg 3 times a day.
Juvenile rheumatoid arthritis - the dosage is calculated individually, based on the ratio of 30 - 40 mg per 1 kg of body weight. The total calculated dosage is divided into 3 to 4 doses per day.
Soft tissue injuries (muscles, ligaments, tendons) – take 400–600 mg 4 times a day every 6 hours.
At painful menstruation– take 400 mg 3-4 times a day.

Nurofen for children (syrup and suppositories) – instructions for use

Nurofen suspension is taken orally. For this required quantity suspension is poured into the supplied measuring spoon or a measuring syringe after thoroughly shaking the bottle.

For children over 12 years of age, Nurofen is given 150–300 mg (7.5–15 ml of solution) 3 times a day to reduce fever and relieve pain, and after relief of symptoms and improvement of condition, the dosage is reduced to 100 mg (5 ml) according to 3 times a day. The maximum permissible daily dosage of Nurofen for children over 12 years of age is 1000 mg (1 kg).

For juvenile rheumatoid arthritis, the dosage of the suspension is calculated individually by body weight, based on the ratio of 30 - 40 mg per 1 kg of weight. The calculated dosage is divided into three doses per day.

In order to reduce fever and symptomatic treatment of childhood infections, colds, acute respiratory viral infections and other similar conditions, Nurofen is given to a child in the following dosages depending on age:

Children aged 3 – 6 months – 50 mg (2.5 ml suspension) three times a day;
Children 6 – 12 months – 50 mg (2.5 mg) 3 – 4 times a day;
Children 1 – 3 years old – 100 mg (5 ml) 3 times a day;
Children 4 – 6 years old – 150 mg (7.5 ml) 3 times a day;
Children 7 – 9 years old – 200 mg (10 ml) 3 times a day;
Children 10 – 12 years old – 300 mg (15 ml) 3 times a day.

The above are the maximum permissible dosages Nurofen for children of all ages. These dosages can be reduced if they are sufficiently effective, but cannot be increased under any circumstances.

If the temperature rises after vaccination, you can give the child 2.5 ml of the suspension once. After 6 hours, if necessary, you can give the child another 2.5 ml of suspension. More than 5 ml of Nurofen syrup per day should not be given to a child to reduce the temperature after vaccination.

Rectal suppositories in children are used for the same purpose as syrup. Suppositories can be chosen if the baby is unable to swallow the solution for some reason, for example, the child is vomiting, and therefore taking the syrup is impossible. Also, candles are preferable if you need to get a quick effect.

The suppositories are inserted into the child’s anus, gently pushing index finger hands. The suppository must be pushed to the inner border of the sphincter, for which it should be inserted with a finger to the middle of the second phalanx.

Children aged 3–9 months are given 1 suppository 3 times a day to reduce fever and relieve pain. And children aged 9 months - 2 years are administered one suppository 4 times a day, every 6 hours.

In order to reduce the temperature that has risen after vaccination, children are given 1 suppository. For children over 1 year old, if necessary, you can introduce another suppository, but only 6 hours after using the first one.

The duration of use of suppositories and suspension of children's Nurofen to reduce temperature is a maximum of 3 days, and for pain relief - 5 days.

Nurofen suppositories and suspension can be used in children suffering from diabetes mellitus because they do not contain sugar. Children's forms of Nurofen should be used with caution if the child has a past or present stomach ulcer, gastritis, ulcerative colitis, or bleeding from organs digestive tract, urticaria, bronchial asthma, eczema, as well as liver and kidney pathologies. You should also be careful when combining Nurofen with other painkillers, diuretics, antihypertensive drugs, as well as anticoagulants (drugs that reduce clotting), methotrexate and lithium compounds.

If a child develops side effects of Nurofen, you must stop using the drug and consult a doctor.

Nurofen gel - instructions for use

Nurofen gel can only be used in adults and children over 12 years of age. The gel is applied locally to areas of the skin to relieve pain and reduce inflammation in various injuries, arthritis, neuralgia and other similar conditions.

For one-time use, squeeze out 4–10 cm of gel from the tube and gently distribute it over the area of the skin with light massage movements, rubbing until completely absorbed into the skin. The gel can be used a maximum of 4 times a day, keeping an interval of at least 4 hours between rubbing into the skin. If the condition does not improve within two weeks after starting to use the gel, then its use should be stopped and consult a doctor.

After applying the gel to the skin, wash your hands with soap and wipe dry. When using the gel, it is necessary to avoid getting it into the eyes, lips and mouth. If the gel accidentally gets into your eyes, lips or mouth, you should rinse them with cold running water.

Nurofen in gel form should not be applied to areas of skin with wounds or other damage, as well as to the areas around the eyes and lips.

Impact on the ability to operate machinery

Nurofen gel does not affect the ability to operate machinery. Other types of Nurofen, including children's, negatively affect the ability to control mechanisms, therefore, during the entire course of use of the drugs, you should avoid any activities related to the need high speed reactions and concentration.

Overdose

An overdose of Nurofen gel is impossible. Other varieties of Nurofen, including children's, can cause overdose symptoms if taken in quantities exceeding the maximum allowable by 2.5 - 3 times or more.

So, the symptoms of an overdose of Nurofen are the following:

Nausea;
Vomit;
Lethargy;
Depression;
Decline blood pressure;
Tachycardia;
Atrial fibrillation;
Stopping breathing;
Acute renal failure.

Treatment of overdose performed by gastric lavage if the drug was taken within an hour ago. If the drug was taken more than an hour ago, then gastric lavage is not performed. A person is given activated carbon, copious amounts of alkaline drink, diuretics and carry out symptomatic therapy aimed at maintaining normal functioning vital organs.

Interaction with other drugs

Gel Nurofen does not interact with medicines. And all other varieties, including children's Nurofen, interact equally with other medications.

Firstly, it is not recommended to use Nurofen in combination with other drugs from the NSAID group (Aspirin, Paracetamol, Ketorol, Nimesulide, etc.).

When Nurofen is used simultaneously with drugs to reduce blood clotting (anticoagulants) and dissolve blood clots (thrombolytics), their effects are enhanced, which can cause bleeding.

Simultaneous use of Nurofen in combination with antidepressants from the group of serotonin reuptake inhibitors (Citalopram, Fluoxetine, Paroxetine, Sertraline, etc.) increases the risk of bleeding from the digestive tract.

Combined use with Cefamandole, Cefoperazone, Cefotetan, Valproic acid and Plicamycin disrupts normal blood clotting.

Nurofen increases the severity of side effects of glucocorticosteroids, mineralocorticoids, estrogens and ethyl alcohol.

Nurofen during pregnancy

Based on the indicated data from clinical and experimental studies, according to the classification of the American FDA, Nurofen belongs to group B drugs, which means that it can be taken freely from the 13th to the 27th week of pregnancy inclusive. In the first trimester of pregnancy, Nurofen cannot be used categorically, since there is no reliable and accurate data on its ability to provoke mutations and deformities of the fetus at this stage of development.

In the last months of pregnancy, Nurofen should not be used, as this can provoke fetal pathology - non-closure of the duct between the ventricles of the heart, as well as post-maturity and complications during childbirth. A blocked duct in the fetus can be treated, but it is better to prevent it than to eliminate it later. And postmaturity and complications during childbirth can provoke various damages fruits, which are also best avoided. Therefore, it is not recommended to use Nurofen during the last month of pregnancy.

During pregnancy, to relieve pain, reduce inflammation and normalize body temperature, Nurofen is used in normal adult dosages, that is, 200 mg 3 to 4 times a day. It is not recommended to increase the dosage of Nurofen to 400 mg 4 times a day. Pregnant women should take Nurofen 200 mg once if necessary to relieve pain. If improvement does not occur within an hour, then you can take another 200 mg of Nurofen. Next appointment can be done no earlier than 6 hours later. If Nurofen is prescribed by a gynecologist to prevent premature birth, then the drug should be taken according to the prescribed regimen.

During pregnancy, Nurofen should not be used by women who suffer from bronchial asthma, heart failure, bleeding disorders, liver, kidney and hearing diseases, as well as high blood pressure.

Nurofen for pain

Nurofen is effective for almost any type of pain, except for pain in the abdomen in the area of the digestive tract, liver or spleen. In other cases, Nurofen is an effective pain reliever, for example, for headaches, pain during menstruation, pain due to adnexitis and inflammatory diseases pelvic organs, toothache, pain in bones, joints, muscles and ligaments, pain arising from sports injuries, etc. Nurofen can be used to relieve pain. But Nurofen will not cure the disease or condition that caused the pain; it only relieves the painful symptom. Therefore, it should be understood that Nurofen is only symptomatic remedy, which must be used in combination with drugs aimed at curing the disease. In this case, Nurofen will make the treatment process calmer, as it relieves pain.

For pain, it is recommended to take Nurofen 200–400 mg every 6 hours, but no more than 4 times a day. The drugs Nurofen Plus and Nurofen Plus N have the most powerful analgesic effect, since in addition to ibuprofen they contain codeine, which enhances the analgesic effect of the former.

Does Nurofen reduce fever?

Nurofen is a highly effective drug for bringing down elevated body temperature caused by any conditions and diseases, for example, influenza, acute respiratory viral infections, colds, reactions to vaccinations, etc. The drug quickly (within 15–30 minutes) brings the temperature down to normal and prevents it from rising again for 4–6 hours. In order to reduce body temperature, the drug is recommended to be used in normal dosages (200–400 mg for adults and 100–200 mg for children) as needed, but not more often than once every 7 hours. In order to reduce body temperature, Nurofen can be used for no more than three days in a row. If after three days the body temperature continues to rise, you should stop taking Nurofen and consult a doctor.

Side effects

Tablets and capsules (for adults)

Tablets and capsules of all varieties of Nurofen for oral administration, intended for adults, can provoke the following side effects from the outside various organs and systems:

1. Gastrointestinal tract:

Nausea;
Vomit;
Feeling of discomfort in the stomach area;
Diarrhea;
Erosive and ulcerative lesions of the mucous membrane of the digestive tract;
Abdominal pain;
Irritation and dryness of the oral mucosa;
Ulceration of gums;
Aphthous stomatitis;

2. Central nervous system:

Headache;
Confusion;
Dizziness;
Insomnia;
Excitation;
Drowsiness;
Depression;
Aseptic meningitis (in people suffering from autoimmune diseases).

3. Sense organs:

Reversible optic neuritis;
Blurred vision;
Diplopia (double objects in front of the eyes);
Dryness and irritation of the mucous membrane of the eye;

Treatment of such a serious disease as prostatitis requires a competent selection of drugs. The role of antibiotics in the treatment of this disease is great, but in addition to them, auxiliary therapy is also needed. After all, very often prostatitis is accompanied by pain and inflammation.

To alleviate the patient’s condition, the doctor prescribes non-steroidal anti-inflammatory drugs. And most often we're talking about about Nurofen tablets.

Indications for use of Nurofen

This is a multifunctional tool, thanks to which you can not only quickly cope with pain of various nature, but also remove inflammation, relieve fever. It helps during migraine attacks, pain in the spine due to osteochondrosis, intercostal neuralgia, painful menstruation, etc.

Types of Nurofen tablets and their purpose

When choosing an anesthetic, you need to take into account the nature of the pain:

For mild pain, Nurofen 200 mg tablets are suitable. They help reduce and eliminate pain for up to 8 hours, relieve headaches, migraines, lower back pain, and also reduce inflammation.
For severe pain, you should take Nurofen Forte 400 mg tablet. One pill contains more active substance than a regular Nurofen tablet. Therefore, the effect of the pill begins very quickly. The drug helps cope with intense pain.
For prolonged pain, the Nurofen Long tablet will help. She has increased efficiency due to the fact that it contains two analgesics at once - ibuprofen and paracetamol. The drug "Nurofen Long" helps when conventional analgesics do not bring the desired result.

Tablets (capsules) “Nurofen Express”

They contain 200 mg of active. They do not contain sucrose, lactose, or gluten. They differ from other drugs in the Nurofen line in that they begin to work within half an hour. The active substance of the drug is quickly absorbed into the blood and acts directly on the source of pain. Nurofen Express tablets help with mild to moderate pain.

Nurofen Long tablets

Effervescent tablets "Nurofen"

New soluble tablets have recently appeared in the Nurofen product line.

Their advantage over conventional hard pills is that:

They are more easily and quickly absorbed by the body;
They do not harm the digestive system;
They do not cause side effects;
They are safe and easy to take, even for an elderly person who has dental problems or finds it difficult to swallow a hard pill.

Nurofen effervescent tablets contain 200 mg of ibuprofen. You can take them no more than 4 times a day.

Nurofen Plus tablets

Unlike regular Nurofen tablets, they are coated. But this is not the main difference. The difference from conventional anti-inflammatory and pain-relieving pills is that, in addition to ibuprofen (200 mg), Nurofen Plus also contains codeine (10 mg), a narcotic substance that enhances the pain-relieving effect of ibuprofen. Therefore, this remedy has a powerful analgesic effect.

Instructions for use

Types of the drug "Nurofen"	Dosage	Maximum dose	Important Tips
Nurofen 200 mg	1 tablet every 4–6 hours, but not more than 6 tablets per day	30 mg of the drug per 1 kg of weight per day (1200 mg)	Used for short term oral administration. If symptoms do not go away after 5 days, you should consult a doctor.
Nurofen Express 200 mg	1 tablet up to 4 times a day. Take the pill with water	1200 mg per day	If 3 days after starting use the symptoms do not go away, but only intensify, you need to stop taking the pills and consult a doctor.
Nurofen Forte 400 mg	1 tablet every 4 hours	1200 mg (no more than 3 tablets in 24 hours)	If necessary, you can use the drug for 10 days. But if the symptoms worsen, you need to see a doctor.
Nurofen Long 200 mg ibuprofen, 500 mg paracetamol	1 pill 3 times a day with an interval of 6 hours.	3 tablets	If symptoms persist after 3 days, you should stop taking the medication and consult a doctor immediately.

Restrictions

Nurofen tablets, like any other medicine, should be prescribed by a specialist. Self-medication with this drug is unacceptable in the following cases:

If the patient is taking other medications that include ibuprofen, aspirin, ketoprofen and other anti-inflammatory substances. Concomitant use of Ibuprofen with such drugs may cause side effects.
If a person regularly takes medications (diuretics, antihypertensive drugs, anticoagulants, thrombolytic drugs, etc.), then Nurofen may reduce the effect of some medications and also cause side effects.
If the patient suffers from asthma. People suffering from asthma attacks and taking the drug Nurofen may experience hypersensitivity (allergic reaction) to the active ingredient of the tablets - ibuprofen, up to bronchospasm.
If a person has crossed the age of 60. In people old age Even a single dose of the drug without a doctor’s prescription can cause a deterioration in your health.

Nurofen's analogs

Change this drug to another drug similar action Can.

The main thing is that the tablets belong to the category of non-steroidal anti-inflammatory drugs.

The most common substitutes for Nurofen tablets are the following medications: Aspirin, Ibuprofen, Nimesil, Indomethacin, etc. But each of these drugs has its own limitations and features of use. Therefore, you cannot decide on your own to change the medication. You need to discuss this point with your doctor.

Cost of Nurofen tablets

The price of the drug in tablet form can vary from 100 to 400 rubles per package, depending on:

Type of drug;
Concentration of the active substance;
Number of tablets per package;
Manufacturer;
Pharmacy markups.

The approximate price of tablets is shown in the table below:

Full name	Active ingredient concentration	Number of tablets per package	Price
Nurofen	200 mg	10 pieces	80 rub.
Nurofen	200 mg	20 pieces	150 rub.
Nurofen-Express	200 mg	16 pieces	250 rub.
Nurofen-Express	400 mg	10 pieces	190 rub.
Nurofen Forte	400 mg	12 pieces	100 rub.
Nurofen Long	200 mg+500 mg paracetamol	6 pieces	175 rub.
Nurofen Long	200 mg+500 mg paracetamol	12 pieces	300 rub.

Nurofen tablets: user reviews

Gennady, 42 years old:

“I took Nurofen tablets during complex treatment prostatitis. Along with antibiotics and drugs that make urination easier, I took this remedy. The temperature went away on the first day of treatment. A inflammatory edema I managed to remove it after 3 days. The product works quickly, I had no side effects. I took the pills strictly according to the instructions: 3 tablets a day.”

Dmitry, 35 years old:

“Nurofen helped me during the treatment of prostatitis. Thanks to him, I forgot what it was like to have a painful urge to urinate, pain in the urethra and rectum. In the phase of exacerbation of prostatitis, I took Nurofen Express tablets, then switched to regular Nurofen. As aid, which eases the course of prostatitis, Nurofen is ideal. And the effect of the medicine is quick, and the price is not bad.”

Frequently Asked Questions

Is it possible to take Nurofen tablets together with other analgesic or anti-inflammatory drugs?

No, you can't. Concomitant use of drugs with similar effects significantly increases the likelihood of side effects. If the patient is not sure whether a particular drug belongs to the group of painkillers or anti-inflammatory drugs, then he should consult a doctor.

Is it possible to take Nurofen tablets from different lines at the same time?

No, you can’t, because the active ingredient in tablets of all types of the Nurofen line is ibuprofen. If a person takes Nurofen Long and Nurofen at the same time, then daily dose ibuprofen will be increased. Do not exceed the daily dosage of 1200 mg of ibuprofen. If Nurofen in its various variations does not help the patient, then you need to consult a doctor and not experiment with your health.

Is it possible to take Nurofen and Paracetamol tablets at the same time?

Yes, you can. The fact is that the drug “Paracetamol” does not belong to the group of non-steroidal anti-inflammatory drugs. This is an antipyretic analgesic, so you can take it simultaneously with Nurofen. Just follow the instructions for use of both products and do not exceed the dosage recommended in the instructions.

Is it possible to take Nurofen tablets with alcohol?

No. Alcoholic drinks can increase side effects and also reduce the effect of ibuprofen, the active substance of Nurofen tablets.

The drug "Nurofen" is a common remedy for relieving the inflammatory process, pain during prostatitis, as well as other diseases: rheumatism, arthritis, headaches and toothaches, ENT diseases, infectious and inflammatory processes. Thanks to the diversity of the Nurofen product line, each patient can choose the ideal medicine for himself, depending on the severity of the disease, the nature and intensity of the pain syndrome.

Nurofen is a medicinal non-steroidal drug complex action. The active substance is ibuprofen, which has an antipyretic effect, relieves pain, eliminates inflammatory processes in the body. Affects the synthesis of prostaglandins, which are mediators of pain. It has a wide range of effects on headaches, acute dental pain, rheumatic pain, pain during menstruation, arthrosis diseases, and migraines. This drug It is actively used for pain that is traumatic in nature, and is often used for sports injuries. Effective for colds and flu-like conditions.

1. Pharmacological action

An anti-inflammatory drug of a non-hormonal nature that has anti-inflammatory and antipyretic effects. It also has a mild antipyretic effect. Achievement Mechanism therapeutic effect associated with selective blocking of enzymes leading to the formation of biologically active substances that have the opposite effect.

Nurofen is absorbed quite quickly and is distributed throughout all tissues in a short time, retaining mainly in the periarticular fluid, where its maximum concentration is achieved. This property of the drug is due to the high degree of binding to plasma proteins (about 90%). The drug enters the joint cavity to a small extent or does not enter at all.

Neutralization of Nurofen occurs in the liver with the formation active products decay. Its elimination occurs through the kidneys and bile. The time it takes to remove the drug from the body is about 4 hours.

2. indications for use

Pain syndrome various localizations and severity;
Fever due to viral infections;
Rheumatoid diseases of the musculoskeletal system;
Inflammatory processes in infectious diseases of the ENT organs.

3. Method of application

Dosage of Nurofen in tablet form for patients childhood in the range of 6-12 years:

The drug is prescribed only for patients whose body weight exceeds 20 kg.

The dosage of Nurofen is as follows: 200 mg of the drug no more than 4 times a day with an interval between doses of at least 6 hours.

Dosage of Nurofen in tablet form for pediatric patients, over 12 years of age and adult patients

The initial dosage of the drug is 200-400 mg with a gradual decrease after achieving the desired effect. The frequency of use of Nurofen is no more than 4 times a day.
In both cases, the maximum dosage of Nurofen is 1.2 g of the drug per day.

Film-coated tablets are taken after meals and washed down with a sufficient amount of warm water. drinking water or milk;
Soluble tablets dissolve in a glass warm water and are taken immediately after meals.

The dosage of the drug can be adjusted by the attending physician, based on the condition of the patients and the dynamics of the treatment process.

Application of Nurofen in the form of ointment or gel:

The drug is applied in a thin layer to the affected areas and rubbed in until it is completely absorbed. The frequency of use of Nurofen is no more than 4 times a day, and when positive dynamics of the treatment process is achieved - no more than 2 times a day.

4. Side effects

Violations nervous system(sleep disturbances, prolonged depression of mood, headaches, dizziness, drowsiness, hallucinations, confusion, drug use, increased nervous excitability);
Violations respiratory system(shortness of breath, bronchospasm);
Disorders of the urinary system (functional failure of the kidneys in acute stage, kidney inflammation, bladder inflammation, frequent urge to urination);
Violations cardiovascular system(increased blood pressure, disorders heart rate, functional heart failure);
Violations digestive system(long-term loss of appetite or complete absence, vomiting, heartburn, nausea, ulcerative lesions of organs, abdominal pain, stool disorders, inflammatory processes of organs oral cavity, inflammation of the pancreas, various irritations of the oral cavity and other organs, inflammation of the liver);
Metabolic disorders (increased sweating);
Sensory organ disorders (various disorders visual perception, various disorders auditory perception, ringing sensation in the ears, inflammation of the conjunctival membranes of the eyes, dryness eyeballs, swelling);
Various allergic reactions(, Lyell's syndrome, Stevens-Johnson syndrome);
Disorders of the hematopoietic system (decreased percentage of leukocytes, decreased percentage of platelets, anemia, increased percentage of agranulocytes).

5. Contraindications

Various violations hematopoietic system;
Severe functional insufficiency of the heart;
Hypersensitivity to the drug and its components;
Congenital or acquired deficiency of the enzyme glucose-6-phosphate dehydrogenase;
Aspirin asthma;
Prolonged increase in blood pressure in a severe stage;
Individual intolerance to the drug and its components;
Various hearing impairments;
Various diseases of the hearing organs;
Pregnancy and lactation;
Expressed functional disorders kidney activity;
Patients age less than 6 years;
Decrease in the percentage of leukocytes;
Various diseases of the organs of vision;
Various diseases of the optic nerve;
Severe functional disorders of the liver.

6. During pregnancy and lactation

Nurofen is contraindicated for use from the 1st to 3rd trimester of pregnancy. For other periods, the drug should be used only in exceptional cases when the benefit from the therapeutic effect of Nurofen far outweighs the harm caused.

The use of Nurofen during lactation should occur only after complete cessation of it.

7. Interaction with other drugs

The simultaneous use of Nurofen with Acetylsalicylic acid leads to a decrease in the therapeutic effect of the latter;
The simultaneous use of Nurofen with drugs that reduce the ability of blood to clot leads to the risk of bleeding of various locations;
The simultaneous use of Nurofen with Cyclosporine leads to increased toxic effects of the latter and the development of toxic damage kidney;
The simultaneous use of Nurofen with Plicamycin, Cefamandole, Cefotetan, Cefoperazone and Valproic acid leads to a decrease in prothrombin levels in the blood plasma;
The simultaneous use of Nurofen with drugs that block or reduce macrosomal oxidation of substances in the body leads to the development of severe liver poisoning;
The simultaneous use of Nurofen with drugs that reduce renal tubular secretion leads to an increase in the concentration of Nurofen in the blood plasma and the development of corresponding side effects;
Simultaneous use of Nurofen with drugs that reduce concentration hydrochloric acid V gastric juice and Cholestyramine, leads to decreased absorption of Nurofen;
The simultaneous use of Nurofen with drugs that reduce glucose content in the form of tablets leads to an increase in the therapeutic effect of the latter;
The simultaneous use of Nurofen with drugs that contain caffeine leads to an increase in the analgesic effect of Nurofen.

8. Overdose

Digestive system disorders (abdominal pain, vomiting, nausea);
Cardiovascular system disorders (heart rhythm disturbances, decreased blood pressure, atrial arrest);
Nervous system disorders (persistent long-term depression of mood, tinnitus, headaches, decreased reactivity, drowsiness);
Respiratory system disorders (respiratory arrest);
Disorders of the urinary system (functional failure of the kidneys in acute form).

To eliminate these symptoms, gastric lavage, the use of drugs that can bind to toxic agents and remove them from the body (Activated carbon and the like) and symptomatic treatment are carried out.

9. Release form

Tablets, 200 mg - 6, 8, 10, 12, 16, 20, 24, 30, 36, 48 or 96 pcs.
Gel, 5% - 30, 50 or 100 g tube.
Rectal suppositories (candles) (for children), 60 mg - 10 pcs.
Oral suspension 100 mg/5 ml - vial. 100 ml or 150 ml

10. Storage conditions

Nurofen is stored in a dry place without access sun rays and outsiders.

Shelf life - no more than 3 years.

11. Composition

100 g gel:

- 5 g;
Excipients: hyaetellose, sodium hydroxide, benzyl alcohol, isopropyl alcohol, purified water.

1 tablet:

- 200 mg;
Excipients: croscarmellose sodium, sodium lauryl sulfate, sodium citrate dihydrate, stearic acid, colloidal silicon dioxide.

suspension 5 ml:

- 100 mg;
Excipients: maltitol syrup, water, glycerol, citric acid, sodium citrate, sodium chloride, sodium saccharinate, xanthan gum, strawberry flavor 500244E, polysorbate, domiphene bromide.

12. Conditions for dispensing from pharmacies

The drug is available without a prescription.

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* Instructions for medical use of the drug Nurofen are published in free translation. THERE ARE CONTRAINDICATIONS. BEFORE USE, YOU MUST CONSULT WITH A SPECIALIST

It has a local analgesic and anti-inflammatory effect. The mechanism of action is due to inhibition of the synthesis of PG - mediators of pain and inflammation.

Pharmacokinetics of the drug Nurofen

When taken orally, it is well absorbed from the gastrointestinal tract. Cmax is created within 1 hour, when taken after meals - within 1.5–2.5 hours. Plasma protein binding - 90%. Slowly penetrates into the joint cavity, but lingers in synovial tissue, creating higher concentrations in it than in plasma. Biological activity associated with the S-enantiomer. After absorption, about 60% of the pharmacologically inactive R-form is slowly transformed into active S-form. Subject to biotransformation. There are 3 known main metabolites excreted by the kidneys. No more than 1% is excreted unchanged in the urine. It has two-phase elimination kinetics with T1/2 from plasma of 2–2.5 hours (for retard forms - up to 12 hours).

Using Nurofen during pregnancy

Caution should be exercised during pregnancy and breastfeeding.

Contraindications to the use of the drug Nurofen

hypersensitivity to ibuprofen, acetylsalicylic acid, other NSAIDs;

Bronchial asthma, urticaria, rhinitis, provoked by taking acetylsalicylic acid(salicylates) or other NSAIDs;

Children's age (up to 12 years).

With caution:

Concomitant diseases of the liver or kidneys, gastrointestinal tract;

Bronchial asthma, urticaria, rhinitis, polyps of the nasal mucosa.

Side effects of the drug Nurofen

abdomen), irritation, dry mucous membranes or pain in the oral cavity, ulceration of the gum mucosa, aphthous stomatitis, pancreatitis, constipation/diarrhea, flatulence, indigestion, possibly - erosive and ulcerative lesion and bleeding from the gastrointestinal tract, liver dysfunction.

From the nervous system and sensory organs: headache, drowsiness, anxiety, nervousness, irritability, psychomotor agitation, confusion, hallucinations, aseptic meningitis (more often in patients with autoimmune diseases), hearing loss, ringing in the ears, reversible toxic amblyopia, blurred vision or double vision, dryness and irritation of the eyes, swelling of the conjunctiva and eyelids (allergic origin), scotoma.

From the cardiovascular system and blood (hematopoiesis, hemostasis): heart failure, tachycardia, increased blood pressure, eosinophilia, anemia, incl. hemolytic, thrombocytopenic purpura, agranulocytosis, leukopenia.

From the respiratory system: shortness of breath, bronchospasm.

From the outside genitourinary system: edema syndrome, renal dysfunction, acute renal failure, polyuria, cystitis.

Allergic reactions: skin rash(erythematous, urticarial), itchy skin, urticaria, allergic rhinitis, allergic nephritis, Quincke's edema, anaphylactic reactions, incl. anaphylactic shock, multiform exudative erythema(including Stevens-Johnson syndrome), toxic epidermal necrolysis.

Other: increased sweating, fever.

Method of administration and dosage of the drug Nurofen

Inside. Adults and children over 12 years old - 1 tablet. (200 mg) 3-4 times a day. To achieve fast therapeutic effect the dose is increased to 2 tablets. (400 mg) 3 times a day. Do not take more than 6 tablets. in 24 hours

Children 6–12 years old (with body weight more than 20 kg) - 1 tablet. no more than 4 times a day.

The maximum daily dose is 1200 mg.

Overdose of Nurofen

Symptoms: abdominal pain, nausea, vomiting, lethargy, drowsiness, depression, headache, tinnitus, metabolic acidosis, coma, acute renal failure, hypotension, bradycardia, tachycardia, atrial fibrillation and respiratory arrest.

Treatment: gastric lavage (only within the first hour after ingestion), activated carbon(to reduce absorption), alkaline drinking, forced diuresis and symptomatic therapy (correction of acid base, blood pressure, gastrointestinal bleeding)

Interactions of Nurofen with other drugs

The simultaneous use of two or more NSAIDs should be avoided due to the increased risk of side effects. With simultaneous use, ibuprofen reduces the anti-inflammatory and antiaggregation effect of acetylsalicylic acid (possibly increasing the incidence of acute coronary insufficiency in patients receiving small doses of acetylsalicylic acid as an antiplatelet agent after starting ibuprofen). When used with thrombolytic drugs (alteplase, streptokinase, urokinase), the risk of bleeding simultaneously increases. Ibuprofen enhances the effect indirect anticoagulants, antiplatelet agents, fibrinolytics.

Inducers of microsomal oxidation (phenytoin, ethanol, barbiturates, rifampicin, phenylbutazone, tricyclic antidepressants) increase the production of hydroxylated active metabolites, increasing the risk of severe hepatotoxic reactions. Microsomal oxidation inhibitors reduce the risk of hepatotoxicity.

Antacids and cholestyramine reduce the absorption of ibuprofen. Caffeine enhances the analgesic effect of ibuprofen. Cefamandole, cefoperazone, cefotetan, valproic acid increase the incidence of hypoprothrombinemia.

Myelotoxic drugs enhance the manifestations of hematotoxicity of ibuprofen. Cyclosporine and gold preparations enhance the effect of ibuprofen on the synthesis of PG in the kidneys, which is manifested by increased nephrotoxicity. Ibuprofen increases the plasma concentration of cyclosporine and the likelihood of developing its hepatotoxic effects. Drugs that block tubular secretion reduce excretion and increase plasma concentrations of ibuprofen.

Ibuprofen reduces the effect of antihypertensive drugs (including CCBs and ACE inhibitors), natriuretic and diuretic activity of furosemide and hydrochlorothiazide, the effectiveness of uricosuric drugs. Increases the side effects of mineralocorticoids, glucocorticoids, estrogens, ethanol. Enhances the effect of oral hypoglycemic drugs and insulin. Increases the blood concentration of digoxin, lithium and methotrexate. Ibuprofen may reduce the clearance of aminoglycosides (coadministration may increase the risk of nephrotoxicity and ototoxicity).

Ibuprofen for intravenous administration should not be mixed with other drugs.

Precautions when taking Nurofen

Treatment with ibuprofen should be carried out in the minimum effective dose, in the shortest possible short course. During long-term treatment it is necessary to monitor the peripheral blood picture and functional state liver and kidneys.

Considering the possibility of developing NSAID gastropathy, it is prescribed with caution to elderly people, with a history of stomach ulcers and other gastrointestinal diseases, gastrointestinal bleeding, with simultaneous therapy with glucocorticoids, other NSAIDs and for long-term therapy. When symptoms of gastropathy appear, careful monitoring is indicated (including esophagogastroduodenoscopy, blood test with determination of hemoglobin, hematocrit, stool analysis occult blood). To prevent the development of NSAID gastropathy, it is recommended to combine it with PGE drugs (misoprostol).

Prescribe with caution to patients with impaired liver and kidney function (regular monitoring of the level of bilirubin, transaminases, creatinine, and renal concentrating ability is required), arterial hypertension and chronic heart failure (daily monitoring of diuresis, body weight, blood pressure). If visual impairment occurs, the dose should be reduced or the drug discontinued.