Persen forte
Persen forte(Persen forte)
Basic physical and chemical characteristics : capsules brown;
Compound. 1 capsule includes 125 mg of valerian extract (Extr. Valerianae radix), 25 mg of lemon balm extract (Extr. Melissae) and 25 mg of peppermint extract (Extr. Menthae piperitae);
other components: magnesium oxide, lactose monohydrate, talc, magnesium stearate, colloidal anhydrous silicon dioxide.
Release form of the medicine. Capsules.
Pharmacotherapeutic group. Sleeping pills and sedatives. ATC code N05CM09.
Action of the medicine. Persen forte is a drug plant origin with a mild sedative effect.
Valerian has a sedative effect. It has a positive effect on symptoms of irritability such as restlessness, agitation and tension due to nervous overstrain. For insomnia, it helps you fall asleep faster.
Melissa also has a sedative and antispasmodic effect.
Peppermint is traditionally used in combination with valerian in sedatives.
Persen Forte is used for neuroses when taking potent sedatives inappropriate.
Indications for use. Persen Forte is prescribed for neuroses accompanied by the following symptoms:
nervous excitement;
anxiety;
decreased concentration;
sleep disorders.
Application and dosage of the drug. Adults and children over 12 years of age: for nervousness, 1 – 2 capsules 2 – 3 times a day.
For insomnia, 1 – 2 capsules an hour before bedtime.
The duration of treatment is unlimited. Even with long-term use no addictive capsules are observed.
After stopping treatment, no withdrawal symptoms were observed.
Side effect. Hypersensitivity reactions are possible.
Contraindications.
Hypersensitivity to the components of the drug.
Not prescribed for children under 12 years of age.
Overdose. Toxic action no drug noted. A single dose of approximately 25 Persen Forte capsules may cause symptoms such as fatigue, spasms abdominal cavity, anxiety, dizziness, hand tremors and dilated pupils. These symptoms disappear within 24 hours.
Features of use.
Use during pregnancy and lactation. Negative action no medications noted. As with the use of medications in general, particular caution should be taken during the first trimester of pregnancy and during breastfeeding Therefore, the decision about the use of the drug must be made by the doctor.
Effect on psychophysical ability . In recommended doses, the drug does not affect the ability to drive a car or operate machinery.
Interaction with other drugs. Not known.
Storage conditions and periods. Store at a temperature not exceeding 25 °C in a dry place.
Keep out of the reach of children!
Shelf life – 3 years.
Do not use the drug after the expiration date.
Persen is a multicomponent herbal medicine with a sedative effect. Available in the form of film-coated tablets and capsules.
Medicines are available in tablet form with trade name Persen. The tablets are round, convex, brown in color. Contains 50 mg of dry matter of valerian extract, and 25 mg of dry extracts of lemon balm and peppermint. The tablet also contains fillers and colorings.
Persen forte is available in capsule form. The capsules are reddish-brown in color and contain 125 mg of valerian rhizome and root extract, as well as 25 mg of mint and lemon balm extracts.
Thus, we will answer the question what is the difference between Persen and Persen forte. It's the same drug in only one the dosage of valerian extract was increased by 2.5 times. In addition to the sedative effect, lemon balm and mint extracts have a slight antispasmodic effect.
This article contains informational information only. Before using or prescribing Persen to a patient, you should read the full leaflet!
Indications for use
In neurology it is used as a mild sedative for the following conditions:
- Astheno-neurotic syndrome.
- An anxiety state that does not require the use of potent drugs.
- Complex therapy of sleep disorders.
Contraindications
An absolute contraindication to the prescription of the drug is intolerance and allergic reactions on any of the components. Contraindications also include:
- Arterial hypotension (due to the existing antispasmodic effect, an orthostatic reaction can be expected in some cases).
- Age up to 3 years when using tablets, age up to 12 years when prescribing capsules.
The use of Persen during pregnancy and lactation has not been studied. Appointment is possible only if the potential benefits over the risk to the fetus or newborn.
Dosage
Most often, the drug is prescribed in a dosage of 2-4 tablets or 1-2 capsules 2-3 times a day. For insomnia or an expected traumatic situation, a single dose of 2-3 tablets or 1-2 capsules is possible. For children from 3 to 12 years of age, the drug is prescribed only under strict medical supervision, usually 1 tablet 3 times a day. The duration of treatment should not exceed 1.5 months.
Cases of overdose have not been described. There have been cases in the literature of taking large quantity rhizomes and roots of valerian (more than 20 grams or over one hundred tablets or 40 capsules of Persen). Symptoms: weakness, lethargy, heaviness in the stomach, dizziness, dilated pupils. All phenomena passed on their own within 24 hours.
Special instructions
The drug has no withdrawal syndrome. When used in the doses used, the drug does not affect the ability to control vehicles or complex mechanisms.
Concomitant use with other sedatives and central nervous system depressants (analgesics central action, some anticonvulsants, sleeping pills) may increase the effect. Long-term use often leads to atonic constipation, a persistent decrease in blood levels blood pressure.
Price for Persen (tablets and capsules)
You can buy the medicine at any pharmacy; its dispensing does not require a prescription. On average, the price is within the following limits (relevance as of 12/21/14):
- Film-coated tablets, package No. 40. 250-340 rubles.
- Capsules, package No. 10. 160-290 rubles.
- Capsules, package No. 20. 250-370 rubles.
- Capsules, package No. 40. 390-500 rubles.
Since the drug is not an essential drug, it is necessary to take into account high probability large markups in some pharmacies. Perhaps, in order to save money, it sometimes makes sense to call the nearest pharmacies and use other information sources.
Persen- This combination drug of plant origin, having sedative And antispasmodic (eliminating spasm of smooth muscles) action. The components of the drug act at the level of the central nervous system ( CNS), reducing its activity. This is manifested by a decrease in reaction to various external stimuli, as well as an easier process of falling asleep ( hypnotic action).Composition of the drug Persen
This drug consists of several active ingredients of plant origin, as well as from excipients.The active components of Persen are:
- dry extract of valerian rhizomes;
- dried lemon balm extract;
- dry peppermint extract.
Excipients are necessary to give the medicine a special form, as well as to preserve the medicinal components in an active state for a long time ( that is, they are also used as stabilizers).
The auxiliary components of Persen are:
- Crospovidone– accelerates the dissolution of the tablet in the gastrointestinal tract and the release of active components.
- Magnesium stearate– filler.
- Corn starch– filler.
- Silicon dioxide colloidal- formative substance.
- Microcrystalline cellulose.
- Lactose.
The mechanism of action of the drug Persen
Mechanism of action of this medication due to the total effects of its active components.The therapeutic effect of Persen is due to:
- Valerian rhizome extract. Contains essential oils, tannins, organic acids, sugars and so on. These components enhance inhibitory processes at the level of the central nervous system, resulting in a decrease in nervous excitation. The person relaxes, becomes calmer, and worries less about issues that previously caused him great anxiety. Due to the described effects, the process of falling asleep is also easier ( especially in case of long-term previous insomnia). Another effect this tool is to eliminate spasm ( overly expressed and painful contraction ) smooth muscle, which is located in many internal organs (in particular in the gastrointestinal tract and genitourinary system).
- Melissa extract. Contains essential oils, flavonoids and other biologically active components. Positive effects at the level of the central nervous system are due to sedative, anxiolytic ( eliminating anxiety and increased restlessness) and antidepressant ( mood-boosting) action. This plant also has antispasmodic effect. In addition, lemon balm preparations enhance the activity of the immune system ( protective) body systems, in particular increasing antiviral immunity ( that is, protection human body from a viral infection).
- Peppermint extract. Has a calming effect, which is due to the constituents of the plant. essential oils and other substances. One of the main active components of peppermint is menthol. In case of contact with the mucous membrane oral cavity it stimulates special nerve receptors, thereby triggering a number of specific reflex reactions. The biologically released active substances (enkephalins, endorphins and others) stimulate expansion blood vessels heart, brain and lungs, thereby improving blood circulation in these organs. Peppermint also has moderate antispasmodic, antiemetic and choleretic effects.
Release forms and analogues of Persen
This medication is intended for oral administration only, so it is available in the form of tablets or capsules. It is worth noting that depending on the form of release, the quantity ( dose) active components of the drug, which affects the effects it provides. The composition and quantity of auxiliary components remain unchanged. Persen tablets
The tablets have a round, biconvex shape and are coated with a special coating dark brown. The tablets are packed in special blisters ( records), each of which contains 10 tablets. They are produced in packs of 2, 4, 6 or 8 blisters.Each Persen tablet contains:
- Valerian rhizome extract– 50 mg.
- Melissa extract– 25 mg.
- Peppermint extract– 25 mg.
Persen forte ( capsules)
The drug is available in the form of dark brown capsules, which may contain small granules or a compressed substance inside. The capsules are also packaged in special blisters ( 10 pieces each) and are available in packages of 1, 2, 4, 6 or 8 blisters.Each capsule of Persen Forte contains:
- Valerian rhizome extract– 125 mg.
- Melissa extract– 25 mg.
- Peppermint extract– 25 mg.
Persen nocturnal ( capsules)
In terms of release form, composition and quantity of active ingredients, this medication is no different from the drug Persen Forte.Persen cardio
This drug has a calming effect and also improves performance cardiovascular system. At the same time, its composition is completely different from other forms of persen.The active components of Persen Cardio are:
- Dry extract of passionflower herb. Affects the central nervous system, stimulating inhibitory processes in it and thereby providing sedative effect. Reduces nervous excitability and emotional stress, facilitates the onset of sleep.
- Dry extract of hawthorn leaves and flowers. Improves the functioning of the heart muscle and stimulates blood circulation in it, as well as improves microcirculation in various organs and tissues. Reduces high blood pressure. Prevents the development of certain heart diseases ( in particular, reduces the risk of arrhythmia - disturbances in the frequency and rhythm of heart contractions).
Analogues ( substitutes) drug Persen
There are many herbal preparations that have a calming effect. They also help relieve nervous tension and emotional overload. These drugs can be used if Persen is ineffective, as well as if there are contraindications to its use.Persen analogues
Drug name | Active components | Effects |
Novo-passit | Contains extracts of valerian rhizomes, lemon balm herb, St. John's wort and passionflower, as well as hawthorn and elderberry flowers. In addition, the drug contains the substance guaifenesin. | Has a sedative and anxiolytic effect ( that is, it relieves anxiety, fear or increased nervous excitement). |
Motherwort extract | Has a sedative and cardiotonic effect. Also helps lower blood pressure. |
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Antares | Intoxicating pepper rhizome extract. | It has a sedative, hypnotic and mild analgesic effect. |
Lykan |
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Fitorelax | Valerian and hawthorn extracts. | Has a calming and relaxing effect. |
Instructions for use of the drug Persen
This medication can be purchased in pharmacies without a doctor's prescription. At the same time, long-term use of the drug without consulting a specialist can lead to the development of unwanted adverse reactions.Indications for use of Persen
As follows from the above, the main effect of Persen is a decrease in the excitability of the central nervous system. Consequently, this drug can be prescribed for any diseases and pathological conditions accompanied by overexcitation of the central nervous system. It is immediately worth noting that various shapes persena ( tablets or capsules) can be prescribed when various diseases, what should be considered when purchasing the drug.Persen tablets can be used:
- With increased nervous excitability. The cause of the development of this pathology may be various stressful situations (problems at work, at school, in the family). It is important to note that stress can be both acute ( one-time psychological trauma ), and chronic ( when a person is stressed for a long time). All of these points can lead to dysfunction of the central nervous system and its overload. As a result of this, patients begin to complain of increased fatigue, decreased concentration, decreased memory, and so on.
- For irritability. Reason increased irritability (nervousness) there may also be stressful situations. In addition, it has been scientifically proven that after just a day without sleep, a person becomes much more irritable than usual. At the same time, he may get upset or nervous because of some little things that previously did not cause him any concern. The reason for this is also a dysfunction of the central nervous system and the emotional sphere.
- With asthenoneurotic syndrome ( neurasthenia). This disease most often occurs in active young people aged 20 to 40 years. The cause of the development of neurasthenia is most often excessive heavy loads at work related to chronic lack of sleep, constant worries, quarrels and other stresses. All this leads to severe overload of the central nervous system, as a result of which characteristic disorders develop. Patients with neurasthenia are constantly tired, drowsy, but at the same time irritable, quick-tempered, and anxious. They themselves may notice a decrease in their ability to work and memory.
- For mild and moderately severe neuroses. Neurosis is a pathological condition of the central nervous system, in which the ability to work is temporarily reduced and mental activity. Also with neurosis there may be increased fatigue (physical and emotional), irritability, emotional instability ( prone to hysterics) and so on. The cause of this pathology is most often various conflict situations that almost everyone has to deal with modern man. If during a conflict some emotions or important thoughts remain unexpressed, this leads to a gradual increase in psychological stress. With each successive conflict, this “suppressed” tension increases, as a result of which at one moment it can “splash out”, manifesting itself in one or more of the above-mentioned symptoms. It is worth noting that severe neuroses, combined with complete loss of ability to work, are treated special medications. Herbal preparations like Persen can be used in the composition complex therapy or during the recovery stage.
- During withdrawal from potent drugs sedatives. Drugs from this group can be used for various mental illness, as well as for the treatment of neuroses, severe neurasthenia and so on. One of the important side effects Most of these drugs experience a so-called withdrawal syndrome. Its essence lies in the fact that after taking the medication for a long time, abruptly stopping it ( that is, abrupt interruption of treatment) may lead to a return of previously existing symptoms, which may be more severe than before treatment. To avoid this, when strong sedatives are discontinued, they can be gradually replaced with herbal medicines.
- For insomnia. This condition characterized by difficulty falling asleep, frequent awakenings, and a feeling of tiredness immediately after waking up. The cause of insomnia can be stressful situations, violation of the work and rest schedule, overwork during the day, active mental work immediately before bed, drinking coffee or tea in the evening, as well as the use of psychostimulants ( medications that increase the activity of the central nervous system). It is immediately worth noting that Persen can facilitate the onset of sleep in these pathologies, however, the use of sedatives should always be combined with the elimination of the factors that led to the development of insomnia. Otherwise, the positive effect will persist only during the treatment period, and after discontinuation of the medication, sleep disturbances will resume.
It is worth noting that capsules can also be used to treat neuroses, neurasthenia, and so on. At the same time, one must take into account the fact that they have a more pronounced ( compared to tablets) have a sedative and hypnotic effect, as a result of which they are recommended for use in severe violations the process of falling asleep.
Separately, it is worth noting the indications for the use of the drug Persen Cardio. On the one hand, it also has a calming and relaxing effect, which is why it can be prescribed for stress, insomnia, overwork, neuroses, and so on. At the same time, due to the presence of a cardiotonic effect, the drug can be used in the presence of discomfort in the area of the heart ( in particular with rapid and increased heartbeat) that arise during times of intense emotion or stress. It is immediately worth noting that similar manifestations may indicate other, more dangerous diseases hearts ( for example, about angina pectoris). Treatment of angina with Persen alone is unacceptable, so if the described symptoms recur quite often, it is recommended to consult a doctor.
Does Persen help with panic attacks?
A panic attack is a sudden state of severe anxiety or fear, accompanied by rapid heartbeat, a feeling of shortness of breath, dizziness, increased sweating, and so on. The duration of a panic attack can range from 1 to 10 minutes, but even after the disappearance acute manifestations the feeling of anxiety may persist for an hour.The causes of the disease are unknown. Not excluded genetic predisposition, dysfunction of the central nervous system, as well as exposure to various stress factors ( especially in adolescence ). Treatment of this disease consists in the use of psychotherapy, as well as the use of medications that affect mental and emotional state patient ( antidepressants, tranquilizers are used).
Use Persen to eliminate acute attack There should be no panic attack, since the therapeutic effects of this drug develop over several hours and gain strength only with prolonged use. At the same time, the use of medication as prophylactic (to relieve nervous tension) may reduce the incidence panic attacks and improve the patient’s neuropsychic state.
Is Persen effective for depression?
Depression is a persistent decline in mood in which a person loses the ability to enjoy anything and sees everything that happens around him only in a negative, negative light. Depression is a mental disorder that requires comprehensive psychotherapeutic and drug treatment (antidepressants are used). Persen is not prescribed for depression, as it inhibits the activity of the central nervous system, as a result of which patients become even more lethargic, drowsy and inactive.Contraindications to the use of Persen
This drug is contraindicated in a number of pathological conditions, as it can intensify them negative impact on the body or provoke the development of new negative reactions. Due to the fact that Persen tablets and capsules contain almost the same components, the contraindications for their use are also the same.The use of Persen in the form of tablets or capsules is contraindicated:
- If you are allergic to the components of the drug. The essence of allergies is that immune system a person reacts too violently to the penetration of certain substances into the tissues of the body. If this happens, within a very short period of time it starts the whole complex immune reactions that can lead to damage to many organs and systems or even death. It is important to remember that allergies can be to both the active substances of Persen ( that is, valerian, lemon balm or peppermint), as well as auxiliary components.
- For lactose intolerance. Lactose is a carbohydrate found in dairy products and is also auxiliary component Persen tablets and capsules ( including persena cardio). The fact is that some people may have a deficiency of lactase, an enzyme that ensures normal digestion of lactose. As a result, lactose taken even in small quantities is not absorbed in the intestine, which leads to the development of certain symptoms ( to bloating, abdominal pain, nausea, vomiting and so on).
- With deficiency of sucrase and isomaltase. These enzymes take part in the digestion of the carbohydrate sucrose, which is part of persen tablets. The shell of the drug in the form of capsules does not contain sucrose, so they can be taken for this pathology.
- For cholelithiasis. Cholelithiasis is characterized by the formation of stones in the biliary tract, which may be accompanied by ( ways) inflammation and disruption of the outflow of bile. The peppermint extract contained in Persen has choleretic effect, that is, it enhances the processes of formation and secretion of bile. However, if there are stones in the biliary tract, this can cause obstruction ( blockages). In this case, the resulting bile will accumulate above the obstruction site, stretching biliary tract and leading to the development of colic ( manifests itself most strongly stabbing pains in the area of the right hypochondrium).
- At peptic ulcer stomach or duodenum. For peptic ulcers on the mucous membranes gastrointestinal tract defects are formed ( ulcerations), in areas where bleeding or perforation of the stomach wall may occur. The use of Persen may contribute to the development of these complications.
Can I take Persen if I have low blood pressure?
It is not recommended to take the drug if you have low blood pressure. The fact is that the active components of the medication have a sedative and relaxing effect, which is often accompanied by a decrease in blood pressure ( due to decreased activity of the so-called sympathetic division nervous system, maintaining the tone of blood vessels).Normal blood pressure is considered to be 120/80 millimeters of mercury, although these figures can vary within slight limits even among healthy people. However, if the pressure drops to 90/60 millimeters of mercury, taking Persen is strictly prohibited, since a further drop in blood pressure can lead to disruption of the blood supply to vital organs ( brain, kidneys and so on).
Can I take Persen during pregnancy?
None of the active ingredients per se are contraindicated during pregnancy. At the same time, pregnant women are not recommended to use the drug, as this can lead to the development of a number of adverse reactions.Persen, like any other medication, can cause allergic reactions. If you ordinary person allergies can occur easily and painlessly ( for example, in the form of a quickly passing skin rash), in a pregnant woman the development of allergic reactions can lead to extremely severe consequences including damage and intrauterine death fetus
It is also worth recalling that the use of Persen may be accompanied by a decrease in blood pressure. This may cause the development of fetal hypoxia ( pathological condition, at which developing fetus begins to lack oxygen). The fact is that the embryo is supplied with oxygen and other vital components through the vessels of the placenta - a special organ that appears in female body during pregnancy. With a pronounced decrease in blood pressure in the mother’s body, the blood flow in these vessels can be reduced below a critical value, which will affect the condition of the fetus.
Is it possible to take Persen while breastfeeding ( during lactation)?
It is not recommended to take the drug while breastfeeding, as this may negatively affect the baby's health. The fact is that some components of the drug ( in particular the active substances of valerian) are excreted together with mother's breast milk, in which they can enter children's body. Of course, the dose of valerian that penetrates into the child’s body is negligible, as a result of which there will be no adverse reactions on the part of the baby’s nervous system. At the same time, it is worth noting that the child’s body ( especially during the first years of life) is extremely sensitive to various foreign products. This is due to the fact that his immune system is not yet fully formed and cannot respond to foreign substances ( including those entering the body with food) as it happens in the body of an adult. As a result, the use of various food additives or medications ( including plant origin) can lead to the formation of allergies to them. As a result of this, in the future ( sometimes throughout the rest of life) the child will not be able to take these substances, as this will be accompanied by the immediate development of allergic reactions.Persen for children
No studies have been conducted on the effect of the drug on children's bodies. Persen in the form of tablets is not recommended for children under 3 years of age, as this can lead to the development of allergic reactions, as well as severe depression of the activity of the nervous system. The drug should be prescribed to children aged 3 to 12 years with extreme caution ( short courses in reduced doses). In this case, it is considered optimal to prescribe 1 tablet of medication 1 – 3 times a day.Persen in the form of capsules, as well as Persen Cardio, is not recommended for use in children under 12 years of age, as this can significantly affect the activity of their central nervous system and slow down the processes. mental development. Also, the use of this medication in children is associated with increased risk development of all the adverse reactions described above.
For children over 12 years of age, the drug is prescribed in the same doses as for adults.
Compatibility of Persen and alcohol
Drinking alcohol during the course of treatment is not recommended, as this can lead to the development of a number of unwanted effects. This is due to the mechanisms of action of the active components of the drug and ethyl alcohol ( ethanol), included in absolutely all alcoholic drinks.At the level of the central nervous system, alcohol has various effects. At low concentrations of ethyl alcohol in the blood, excitation of the central nervous system may be observed, accompanied by an increase motor activity, nervousness, irritability and other symptoms characteristic of lung stage intoxication. The use of Persen in this case may be ineffective, since the active components of the drug will not be able to eliminate the increased nervous excitability caused by ethanol. Moreover, if alcohol intake occurred during previous treatment with Persen, all previously achieved positive effects ( reducing irritability, normalizing sleep, etc.) may be lost.
At high concentration ethyl alcohol in the blood ( what is noted during severe intoxication) inhibition processes begin to predominate in the central nervous system, that is, all brain functions are inhibited. A severe overdose of alcohol in itself can lead to depression of the respiratory or vasomotor centers ( located in the brain stem), which in severe cases can lead to the death of the patient. Alcohol abuse while taking Persen ( which also inhibits the activity of the central nervous system) may contribute to the development of these adverse reactions.
Considering the above, it follows that during treatment it is best to completely abstain from alcoholic beverages. In small doses they may reduce effectiveness therapeutic effect the drug, and in large cases - lead to depression of the central nervous system, impaired consciousness, or even death.
Is it possible to take Persen while driving? when driving a car)?
While using the drug, you should refrain from driving vehicles, as well as from performing any other activities that require increased attention and quick responses. This is explained by the inhibitory effect of the active components of the drug, which they have at the level of the central nervous system. This is especially true when using Persen capsules containing an increased dose of valerian. The person himself may not notice any deviations in his behavior ( especially at the beginning of treatment), however, the speed of reactions and responses during the use of the medication certainly decreases, which can create danger when driving.People who take large doses drug. It is highly recommended not to drive for patients who have taken the drug within the last 3 to 4 hours. This applies to both preparations containing valerian and persen cardio.
After completing the course of treatment, normal activity of the central nervous system and speed of reactions are restored within a few days ( depending on the duration of previous treatment).
Application and dosage ( how to drink persen?)
The drug should be taken exclusively orally with a small amount ( 100 ml) warm water. You can take the medication at any time of the day, regardless of meals. At the same time, it is worth remembering that the active components of the drug have a relaxing and hypnotic effect, which must be taken into account when drawing up a treatment regimen.Persen dosage
Indications | Persen ( pills) | Persen forte | Persen nocturnal | Persen cardio |
With increased nervous excitability | 2 - 3 tablets 2 - 3 times a day ( in the morning, at lunch and in the evening before bed). Maximum daily dose– 12 tablets. | 1 – 2 capsules 2 – 3 times a day. The maximum permissible daily dose is 9 capsules. | Orally, 1 capsule of the drug 1 – 2 times a day. Therapeutic effect develops slowly and reaches a maximum after 5–6 weeks. |
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For insomnia | 2 - 3 tablets 40 - 60 minutes before bedtime. | 1 – 2 capsules 40 – 60 minutes before going to bed. |
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The duration of taking the drug without consulting a specialist should not exceed 6–8 weeks.
Side effects of Persen
Side effects can rarely develop in healthy people, which may be due to intolerance to the drug, as well as hypersensitivity to some of its components ( allergic reactions are the most common).An allergy to the components of Persen may manifest itself:
- Redness of the skin ( in the area of the limbs, abdomen, back). This effect is due to the expansion of superficial blood vessels, resulting from the release of a large amount of biologically active substances into the bloodstream.
- Skin rash. It also develops as a result of dilation of blood vessels.
- Edema. The reason for their development is the expansion of blood vessels, increased permeability vascular wall and the release of the liquid part of the blood into the intercellular space.
To others side effect, observed at long-term use medication, there may be constipation. The development of this phenomenon is associated with changes in intestinal microflora, which is caused by lactose, which is part of the medication. Also, with long-term use of Persen Cardio, nausea, vomiting or diarrhea may occur ( diarrhea), which is due to the action of the active components of hawthorn.
If you experience any discomfort or adverse reactions during treatment, you should immediately stop taking the drug and consult your doctor.
Is Persen addictive?
The drug contains herbal components that do not cause addiction or dependence. After stopping treatment ( even with abrupt discontinuation of the drug after prolonged use) no withdrawal phenomenon is observed.Persen overdose
The drug contains extremely small concentrations of plant components, making it very difficult to achieve an overdose. However, it has been found that taking 25 capsules or 60 tablets of Persen at the same time may cause certain systemic manifestations. Taking 20 grams of valerian extract ( which is equal to 103 tablets of Persen) can cause the development of a number of severe adverse reactions from various organs and systems.An overdose of Persen can manifest itself:
- severe drowsiness;
- loss of consciousness ( rarely);
- dizziness;
- nausea;
- vomiting;
- paroxysmal abdominal pain;
- trembling of hands;
- dilation of the pupils.
Price of the drug Persen
The price of this drug may vary depending on the form of release and the concentration of active substances.Price of the drug Persen in various cities of Russia
City | Persen ( 40 tablets) | Persen forte ( 10 capsules) | Persen nocturnal ( 10 capsules) |
Moscow | 358 rubles | 196 rubles | 220 rubles |
Saint Petersburg | 195 rubles | 235 rubles |
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Novosibirsk | 318 rubles | 217 rubles | |
Yekaterinburg | 289 rubles | ||
Rostov-on-Don | 286 rubles | 190 rubles | 200 rubles |
Krasnoyarsk | 289 rubles | ||
Saratov | 195 rubles | 207 rubles |
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Voronezh | 320 rubles | 165 rubles | 228 rubles |
The drug Persen Cardio is not sold in Russia ( it can only be purchased in pharmacies in Ukraine or Belarus).
Instructions
by application medicinal product for medical use
Registration number:
P N013803/01-290708
Trade name of the drug:
Persen ® Night.
Dosage form:
Compound:
Composition of one capsule: active ingredients: valerian rhizomes with roots extract (dry) – 125,000 mg; lemon balm medicinal leaves extract (dry) – 25,000 mg; peppermint leaf extract (dry) – 25,000 mg; excipients: magnesium oxide – 6,000 mg; lactose monohydrate – 85,500 mg; magnesium hydrosilicate – 8,100 mg; magnesium stearate – 2,200 mg; colloidal silicon dioxide anhydrous – 3,200 mg; capsule shell: titanium dioxide E171 – 1.3690%; iron oxide red E172 0.7527%; yellow quinoline E104 – 0.0153%; sunset yellow E110 (sunset yellow) – 0.0368%; azorubine E122 – 0.0438%; methyl parahydroxybenzoate E128 – 0.2945%; propyl parahydroxybenzoate E126 – 0.1241%; gelatin – 97.3638%.
Description: capsules No. 2 (body and lid) are reddish-brown in color, the contents of the capsules are granules or a compressed mass from greenish-brown to brown with inclusions.
Pharmacotherapeutic group:
sedative of plant origin.
ATX code: N05CM.
Pharmacological properties
The drug has a calming and antispasmodic effect. Rhizome extract with valerian roots has a calming effect. Melissa leaf extract has a calming and antispasmodic effect, peppermint leaf extract has an antispasmodic and moderate calming effect.
Indications for use
Insomnia (difficulty falling asleep) associated with increased nervous excitability.
Contraindications
Hypersensitivity to the components of the drug;
lactase deficiency, lactose intolerance, glucose-galactose malabsorption;
arterial hypotension;
cholangitis, cholelithiasis and other diseases of the biliary tract;
pregnancy;
period breastfeeding;
childhood up to 12 years old. With caution: patients with gastroesophageal reflux disease (GERD).
Directions for use and doses
Orally, take the capsules with a small amount of water, regardless of meals.
For insomnia, adults and children over 12 years of age should take 1-2 capsules 1 hour before bedtime.
You should not take the drug continuously for more than 1.5-2 months. The course of treatment is 2-4 weeks.
To increase the duration of treatment, you should consult your doctor.
When treatment is stopped, withdrawal syndrome does not occur.
Side effect
Possible allergic reactions (hyperemia, skin rash, peripheral edema, allergic dermatitis), bronchospasm, and with long-term use – constipation.
Overdose
A single dose of 20 g of rhizomes with valerian roots (approximately 39 capsules of Persen ® Night) can cause a feeling of fatigue, stomach cramps, a feeling of tightness in the chest, dizziness, trembling hands, dilated pupils, which may disappear on their own within 24 hours.
In case of overdose, it is advisable to perform gastric lavage and consult a doctor.
Interaction with other drugs
The drug enhances the effect of sleeping pills and other medicines, depressing the central nervous system (CNS), antihypertensive drugs(in particular, central action), painkillers, which requires dose adjustment.
Special instructions
Patients with GERD may experience worsening symptoms.
If insomnia symptoms persist or worsen while using the drug, you should consult your doctor.
The drug should not be used continuously for more than 1.5-2 months.
Impact on the ability to drive vehicles and machinery
During treatment with the drug, caution should be exercised when performing potentially dangerous species activities requiring increased concentration attention and speed of psychomotor reactions (driving vehicles, working with moving mechanisms, working as a dispatcher and operator).
Release form
Capsules
Primary packaging:
10 capsules per blister made of aluminum and polyvinyl chloride/thermoelast/polyvinylidene chloride foil.
Secondary packaging: 1,2,4,6 or 8 blisters per cardboard box along with instructions for use.
Storage conditions
In a dry place at a temperature not exceeding 25°C.
Keep out of the reach of children.
Best before date
3 years.
Do not use after expiration date.
Conditions for dispensing from pharmacies
Over the counter.
Manufacturer
RU holder: Sandoz d.d., Verovshkova 57, 1000 Ljubljana, Slovenia;
Produced:
Lek d.d. Verovškova 57, 1526 Ljubljana, Slovenia.
Consumer complaints should be sent to Sandoz CJSC:
125315, Moscow, Leningradsky Prospekt, 72, bldg. 3.
Trade name of the drug:
Persen ® Night.Dosage form:
capsules.Compound:
Composition of one capsule: active ingredients: valerian rhizomes with roots extract (dry) – 125,000 mg; lemon balm leaf extract (dry) – 25,000 mg; peppermint leaf extract (dry) – 25,000 mg; excipients: magnesium oxide – 6,000 mg; lactose monohydrate – 85,500 mg; magnesium hydrosilicate – 8,100 mg; magnesium stearate – 2,200 mg; colloidal silicon dioxide anhydrous – 3,200 mg; capsule shell: titanium dioxide E171 – 1.3690%; iron oxide red E172 0.7527%; yellow quinoline E104 – 0.0153%; sunset yellow E110 (sunset yellow) – 0.0368%; azorubine E122 – 0.0438%; methyl parahydroxybenzoate E128 – 0.2945%; propyl parahydroxybenzoate E126 – 0.1241%; gelatin – 97.3638%.The drug enhances the effect of hypnotics and other drugs that depress the central nervous system (CNS), antihypertensive drugs (in particular, centrally acting), painkillers, which requires dose adjustment.
Special instructions
Patients with GERD may experience worsening symptoms.If insomnia symptoms persist or worsen while using the drug, you should consult your doctor.
The drug should not be used continuously for more than 1.5-2 months.
Impact on the ability to drive vehicles and machinery
During treatment with the drug, care should be taken when performing potentially hazardous activities that require increased concentration and speed of psychomotor reactions (driving vehicles, working with moving mechanisms, working as a dispatcher and operator).
Release form
CapsulesPrimary packaging: 10 capsules per blister made of aluminum and polyvinyl chloride/thermoelast/polyvinylidene chloride foil.
Secondary packaging: 1,2,4,6 or 8 blisters per cardboard box along with instructions for use.
Storage conditions
In a dry place at a temperature not exceeding 25°C.Keep out of the reach of children.
