A lack of magnesium in the human body leads to a number of pathological conditions. Even serious health problems are sometimes solved by replenishing this substance. An effective remedy To eliminate magnesium deficiency, take the drug Magne-B6. How and under what conditions should this medicine be taken correctly? What side effects and contraindications are important to know about before starting treatment with Magne-B6?
The role of magnesium in the human body
Magnesium is necessary for bones, heart, muscles, liver, kidneys. Total quantity of this element in the human body is approximately 25 g. daily requirement for women - 300 mg, men - 350 mg. Pregnant and breastfeeding mothers should receive up to 925 mg (dose for expectant mothers) and 1250 mg (dose for women during lactation) of magnesium daily. What role does this element play in the body? Magnesium takes part in:
- protein synthesis;
- regulation cell growth;
- removal harmful substances;
- normal operation nervous system;
- regulation;
- prevention urolithiasis;
- phosphorus metabolism;
- maintaining normal functioning of the heart muscle.
Release form of Magne B6
To treat magnesium deficiency, doctors may prescribe Magne B6 tablets. They are sold in packs of 30 and 50 pieces. Composition of Magne B6 tablets: 470 mg magnesium lactate dihydrate (corresponding to 48 mg magnesium), 5 mg pyridoxine hydrochloride. If necessary, the doctor prescribes a solution. contain 10 ml of the drug. Composition of Magne B6 solution: 10 mg pyridoxine hydrochloride, 186 m sodium lactate dihydrate, 936 mg magnesium pidolate (corresponding to 100 mg magnesium).
Indications for use Magne-B6
Since magnesium is essential for the normal functioning of all body systems, its deficiency affects the condition of almost all vital organs. Magne-B6 is often prescribed for painful conditions when other medications are not effective or the causes of the disorder are not clear. How and why do they take magnesium B6? Let's look at what pathologies different systems The body is advised to take this drug:
- Cardiovascular system Magnesium is needed for abnormal heart rhythm, atherosclerosis, high cholesterol, ischemia, tendency to thrombosis, pain in the heart.
- Nervous system disorders associated with increased irritability, insomnia, depression, nervous tics treated with Magne-B6.
During pregnancy
When planning a pregnancy, doctors recommend drinking Magne-b6. This will help prevent and eliminate some problems so that you can carry your baby without difficulty and keep him healthy. good condition nervous system moms. Why do you need magnesium b6 during pregnancy? It is important for expectant mothers to provide their bodies with useful microelements and substances while carrying a child. Magnesium is one of them. It is important for correct and normal development fetus
The nervous and other systems of a pregnant woman will not be able to function normally without a sufficient supply of Mg. This element can be absorbed from. Expectant mothers should include buckwheat, oatmeal, dried fruits, and legumes in their diet. But as the fetus grows, a pregnant woman’s need for magnesium increases, so the doctor may prescribe her to take Mg B6.
How does maternal use of Magne-B6 affect the fetus? Medical research has proven that there is no negative influence this drug for correct use doesn't bring. However, this does not mean that pregnant women are allowed to drink it without a doctor’s prescription. Only a doctor after an examination can, if necessary, prescribe to the expectant mother magnesium to eliminate or prevent its deficiency. A gynecologist may prescribe Magne-B6:
- when a woman complains of a high degree of irritability, constant mood swings, bad dream, stress;
- with uterine tone to avoid spontaneous abortion;
- with strong early toxicosis;
- at ;
- for spasms and intestinal colic;
- at fatigue;
- with tingling and numbness of the limbs;
- with malnutrition;
- at ;
- with intense fetal movement in the last months of pregnancy, because sometimes this indicates oxygen starvation fetus due to lack of magnesium.
For children
The doctor will prescribe Magne-B6 for the child if there is a severe deficiency of this element. Lack of magnesium in children is expressed in increased nervous excitability, insomnia, anxiety attacks, stress, muscle spasms, etc. After replenishing magnesium levels in children's bodies, their mothers noticed that children and teenagers became calmer, more attentive and slept better.
Instructions for use and dosage
Magne-B6 is available in tablets and solution (ampoules), photo below. Children under 6 years of age are prescribed magnesium in liquid form. Magne-B6 is also produced in the form of a gel in a tube. In this form, the drug is given to children after 3 years of age after meals. Children under 5 years old are given 5 g once a day, children from 5 to 12 years old - 10 g, and adolescents over 12 years old - 15 g. Never start drinking magnesium without consulting your doctor.
Film-coated tablets
How and how much to take Magne-B6? It is taken with food 2-3 times a day, washed down with 1 glass drinking water. Children over 12 and adults with severe shortage magnesium drink 6-8 tablets. In this dosage form, the doctor prescribes the drug to children over 6 years of age who weigh 20 kilograms or more. Pediatricians prescribe 4-6 magnesium tablets per day for children. How to take Magne B6 during pregnancy? For expectant mothers with magnesium deficiency, the drug is prescribed to take 2 tablets three times a day, and to prevent a deficiency of this element - 2 tablets once a day.
Oral solution
To eliminate magnesium deficiency, adults are prescribed 3-4 ampoules, and children - 1-3 ampoules per day. In each case, the doctor will determine an individual daily norm for the patient. One ampoule contains 10 mg of magnesium B6. Treatment with the drug continues for up to 1 month. To extract the solution from the ampoule, you do not need to file it with a nail file, but you just need to break off its tip with a sharp movement, having previously wrapped it in a cloth. How long to take magnesium is determined by your doctor.
Side effects and contraindications
Before you start taking Magne-B6, you need to familiarize yourself with the available contraindications and possible side effects of this medicine. In case of moderate renal failure, magnesium intake can provoke the development of hypermagnesemia. If a negative reaction to Magne-B6 occurs, you should stop drinking and consult a doctor for advice on this matter. Side effects of the drug include:
- skin and other types of allergies;
- nausea;
- painful sensations in the stomach;
- vomit;
- diarrhea;
When taking the drug while breastfeeding, it should be taken into account that magnesium passes into the baby’s body during feeding along with mother’s milk. If a person has a deficiency of calcium and magnesium, then the deficiency of Mg is first eliminated, and then Ca. The medicine contains sucrose, so diabetics should consult a doctor before starting treatment with this medication. Magne-B6 is contraindicated in the following conditions:
- age up to 6 years (for taking tablets), up to 1 year (for taking solution);
- sensitivity to components of magnesium B6;
- syndrome of impaired glucose absorption;
- fructose intolerance;
- concurrent use of levodopa;
- sucrose-isomaltose deficiency;
An overdose of magnesium B6 does not cause toxic reactions during normal kidney function. However, there is a risk of drug poisoning in people with kidney failure. In this case, there may be following symptoms: vomiting, low blood pressure, depression, coma, respiratory depression, cardiac arrest. In case of an overdose of the drug, rehydration (replenishment of fluid in the body) is indicated, and in the presence of renal failure, hemodialysis (blood purification using a “blood purification” device) artificial kidney»).
Approximate cost of the drug
The price of magnesium B6 medicine depends on the manufacturer. If the drug is foreign-made, then its cost will be more than its analogue from Russian manufacturers. Pharmacies may have different drug prices because they have different drug suppliers. For example, Magne-B6 in tablets costs 818 rubles for 50 pcs., and in ampoules - 395 rubles for 10 amps. 10 ml.
Analogs to the drug Magne-B6
What can replace Magne-B6 treatment? International name this medicine is Comb drug. Other drugs that are analogues are also registered under this name. of this medication. Russian substitute Magne-B6 is . Pharmacies sell analogues of this drug: Hungarian Beres Plus, Polish Magnefar and Magvit v6, Ukrainian Magnikum. Magne-B6 substitutes have different prices, so buyers have a choice.
Thank you
Magne B6 is a drug that replenishes the deficiency of magnesium and vitamin B 6 in the human body, regardless of the reasons that provoked it. The drug is used for the prevention and treatment of magnesium deficiency and related disorders, such as sleep disorders, nervous excitability, mental or physical fatigue, pain and muscle spasms, anxiety attacks with hyperventilation, as well as asthenia.
Composition, release forms and varieties of Magne B6
Currently, the drug is available in two varieties - Magne B6 And Magne B6 forte. On pharmaceutical market in some CIS countries (for example, in Kazakhstan) Magne B6 forte is sold under the name Magne B6 Premium. The difference in names is due only to the marketing work of the manufacturing company, since Magne B6 Forte and Magne B6 Premium are absolutely identical drugs. Magne B6 and Magne B6 forte differ from each other only in dosage active ingredients, of which there are twice as many in the second preparation. Otherwise, there are no differences between the varieties of the drug. Magne B6 is available in two dosage forms:
- Tablets for oral administration;
- Oral solution.
The composition of tablets and solution of both varieties of Magne B6 as active ingredients includes the same substances - magnesium salt and vitamin B 6, the amount of which is reflected in the table.
| Active components of Magne B6 tablets (amount per tablet) | Active components of Magne B6 forte tablets (amount per tablet) | Active components of Magne B6 solution (amount per ampoule) |
| Magnesium lactate dihydrate 470 mg, corresponding to 48 mg of pure magnesium | Magnesium citrate 618.43 mg, which corresponds to 100 mg of pure magnesium | Magnesium lactate dihydrate 186 mg and magnesium pidolate 936 mg, equivalent to 100 mg pure magnesium |
| Vitamin B6 in the form of pyridoxine hydrochloride – 5 mg | Vitamin B6 in the form of pyridoxine hydrochloride – 10 mg |
Thus, as can be seen from the table, one tablet of Magne B6 forte contains the same amount of active substances as one full ampoule of solution (10 ml). And Magne B6 tablets contain two times less active substances compared to a full ampoule of solution (10 ml) and Magne B6 forte. This should be kept in mind when calculating dosages for taking the drug.
Auxiliary components of both varieties of Magne B6 are also reflected in the table.
| Excipients of Magne B6 tablets | Excipients of Magne B6 forte tablets | Excipients of Magne B6 solution |
| Titanium dioxide | Hypromellose | Sodium disulfite |
| Carnauba wax | Titanium dioxide | Sodium saccharinate |
| Acacia gum | Lactose | Cherry caramel flavor |
| Kaolin | Macrogol | Purified water |
| Carboxypolymethylene | Magnesium stearate | |
| Magnesium stearate | Talc | |
| Sucrose | ||
| Talc |
Magne B6 and Magne B6 forte tablets have the same oval, biconvex shape and are painted in a shiny white color. Magne B6 is packaged in cardboard boxes 50 pieces each, and Magne B6 forte - 30 or 60 tablets.
Magne B6 oral solution is bottled in sealed ampoules of 10 ml. The package contains 10 ampoules. The solution is colored brown transparent and has a characteristic caramel smell.
Therapeutic effect
Magnesium plays important role in various physiological processes in the body, ensuring the process of transmitting impulses from nerve fibers to muscles, as well as contractions muscle fibers. In addition, magnesium reduces excitability nerve cells and ensures the activation of a number of enzymes, under the influence of which cascades of important biochemical reactions metabolism in various organs and fabrics. Magnesium deficiency can develop due to the following reasons:
- Congenital pathology of metabolism, in which this element is poorly absorbed in the intestines from food;
- Insufficient intake of the element into the body, for example, due to malnutrition, starvation, alcoholism, parenteral nutrition;
- Malabsorption of magnesium in digestive tract for chronic diarrhea, gastrointestinal fistulas or hypoparathyroidism;
- Loss of large amounts of magnesium due to polyuria (urine excretion in a volume of more than 2 liters per day), taking diuretics, chronic pyelonephritis, renal tubular defects, primary hyperaldosteronism or the use of Cisplastin;
- Increased need for magnesium during pregnancy, stress, taking diuretics, as well as during high mental or physical stress.
Magne B6 - indications for use
Both varieties of Magne B6 have the same the following readings for use:1. Identified and supported by data laboratory tests Magnesium deficiency, in which a person has the following symptoms:
- Irritability;
- Sleep disorders;
- Spasms of the stomach and intestines;
- Heartbeat;
- Muscle spasms and pain;
- Tingling sensation in muscles and soft tissues.
Magne B6 - instructions for use
Magne B6 tablets
Magne B6 in tablet form is intended only for adults and children over 6 years of age. Children under 6 years of age should be given the drug in the form of an oral solution. The tablets must be taken with meals, swallowed whole, without biting, chewing or crushing in any other way, and with a glass of still water.
The dosage of Magne B6 is determined by the person’s age:
- Adults and adolescents over 12 years of age – take 6–8 tablets per day (2 tablets 3 times a day or 4 tablets 2 times a day);
- Children over 6 years old with a body weight of more than 20 kg - take 4 - 6 tablets per day (2 tablets 2 - 3 times a day).
Dosages of Magne B6 forte are determined by the person’s age:
- Adults and adolescents over 12 years of age - take 3-4 tablets per day (1 tablet 3 times a day or 2 tablets 2 times a day);
- Children 6 - 12 years old - take 2 - 4 tablets per day (1 tablet 2-3 times a day or 2 tablets 2 times a day).
The average duration of treatment is 3 – 4 weeks. If the drug is taken to eliminate magnesium deficiency, then the course of treatment is completed when, according to the results of laboratory tests, there is normal concentration of this element. If the drug is taken with for preventive purposes, then the course of treatment is 2–4 weeks.
Special instructions
In case of moderate and mild renal failure, the drug should be used with caution, constantly monitoring the level of magnesium in the blood, since due to the low rate of excretion of the drug by the kidneys, there is a risk of developing hypermagnesemia ( increased concentration magnesium in the blood). If renal failure severe and CC (according to the Rehberg test) is less than 30 ml/min, then Magne B6 is contraindicated for use in any form (both tablets and solution).Children aged 1 – 6 years should be given Magne B6 only in solution form. Children over 6 years of age who weigh more than 20 kg can be given Magne B6 in tablet form (including Magne B6 forte). But if a child over 6 years old has a body weight of less than 20 kg, then he cannot be given the drug in tablets; in this case, a solution should be used.
If a person has a severe degree of magnesium deficiency, then before taking Magne B6, several intravenous injections appropriate medications.
If a person has a combined deficiency of calcium and magnesium, then it is first recommended to take a course of Magne B6 to eliminate the deficiency of magnesium, and only after that start taking various biologically active additives and drugs to normalize calcium levels in the body. This recommendation is due to the fact that in conditions of magnesium deficiency, calcium entering the body is very poorly absorbed.
If a person often drinks alcoholic beverages, laxatives, or constantly endures heavy physical or mental stress, then he can take Magne B6 to prevent magnesium deficiency in the body without any special tests. In this case, the usual preventive course is 2–3 weeks, and it can be repeated every 2–3 months.
Magne B6 solution as excipients contains sulfite, which can increase the manifestations of allergies, which must be kept in mind and taken into account by people prone to hypersensitivity reactions.
When taking the drug in high dosages(more than 20 tablets of Magne B6 forte and more than 40 tablets or 40 ampoules of Magne B6) over a long period of time there is a risk of developing axonal neuropathy, which is manifested by numbness, impaired pain sensation, tremor of the arms and legs and gradually increasing loss of coordination of movements. This disorder is reversible and disappears completely after discontinuation of the drug.
If, despite taking Magne B6, the symptoms of magnesium deficiency (excitability, muscle cramps, irritability, insomnia, fatigue) do not decrease or go away, then you should stop using the drug and consult a doctor to clarify the diagnosis.
Impact on the ability to operate machinery
Neither tablets nor Magne B6 solution affect a person’s ability to control mechanisms, therefore, while taking any form of the drug, you can exercise various types activities requiring high speed reactions and concentration.Overdose
An overdose of Magne B6 is possible, but, as a rule, this occurs against the background of renal failure. In people who do not suffer from kidney disease, an overdose of Magne B6 is usually not observed.Symptoms of an overdose of Magne B are the following:
- Reduced blood pressure;
- Nausea;
- CNS depression;
- Reduced severity of reflexes;
- Changes on the ECG;
- Respiratory depression up to paralysis;
- Anuria (lack of urine).
Interaction with other drugs
Magne B6 reduces the severity therapeutic action Levodopa. Therefore, it is recommended to avoid the combined use of Levodopa with Magne B6, however, if there is an urgent need to take these drugs, then additionally you should mandatory prescribe peripheral dopa decarboxylase inhibitors (Benserazide, etc.). In other words, the combination of Levodopa and Magne B6 is possible only with additional intake the third drug from the group of dopa decarboxylase inhibitors.Calcium and phosphate salts impair the absorption of magnesium in the intestines, so they are not recommended for use simultaneously with Magne B6.
Magne B6 reduces the absorption of tetracyclines (Tetracycline, Oxytetracycline, Chlortetracycline, Doxycycline) in the intestine, so an interval of at least 2 to 3 hours should be maintained between taking these drugs. That is, Magne B6 should be taken either 2 - 3 hours before or 2 - 3 hours after taking a tetracycline antibiotic.
Magne B6 weakens the effects of thrombolytic agents (Streptokinase, Alteplase, etc.) and anticoagulants (Warfarin, Thrombostop, Phenilin, etc.), and impairs the absorption of iron preparations (for example, Fenyuls, Ferrum Lek, Sorbifer Durules, etc. .).
Magne B6 during pregnancy
Magne B6 is approved for use during pregnancy because long-term observations and experimental studies have not revealed any negative effects this drug on the fetus and on the mother.Magne B6 is widely prescribed to pregnant women, since its benefits are obvious in almost all cases. Thus, magnesium, which is part of the drug, helps reduce excitation in the central nervous system, due to which the woman becomes calmer, nervousness, moodiness, mood swings, etc. disappear. Of course, the calmness of the expectant mother has a positive effect on the child.
Vitamin B 6, also included in the preparation, is necessary for normal height and development of the fetal nervous system and heart. Against the background of vitamin B6 deficiency, the fetus may develop malformations of the heart, its valve apparatus or the central nervous system. Magne B6 prevents such pregnancy complications.
Thus, it is obvious that Magne B6 improves not only physical condition pregnant woman and eliminates uterine hypertonicity, but also has a positive effect on the emotional background and relieves unnecessary stress.
However, Magne B6 is prescribed to almost all pregnant women in fairly long courses, even if the woman does not have a threat of miscarriage, hypertension, tics, etc. This practice is due to the fact that during pregnancy the consumption and need for magnesium doubles, and quite often a woman does not receive required quantity microelement with food or vitamins, as a result of which she develops certain symptoms of microelement deficiency. Therefore, doctors consider the prophylactic prescription of Magne B6 to be justified in order to prevent deficiency of magnesium and vitamin B6.
Remember that Symptoms of magnesium deficiency are:
- Spasms, cramps, tics in muscles, nagging pain in the lower back or lower abdomen;
- Dizziness, headaches, sleep disorders, irritability;
- Arrhythmia, high or low blood pressure, palpitations, heart pain;
- Nausea, vomiting, alternating constipation with diarrhea, cramps and abdominal pain;
- Tendency to edema, low body temperature, constant chilliness.
During pregnancy, it is optimal to take 2 tablets of Magne B6 or 1 tablet of Magne B6 forte 3 times a day with meals.
Magne B6 for children
Magne B6 is prescribed to children to eliminate or prevent magnesium deficiency. In some cases, the drug is prescribed “just in case,” since clinical observations have shown that taking Magne B6 has a positive effect on general condition A child who sleeps better becomes calmer, more attentive, more diligent, and is less likely to be capricious and nervous. Of course, such effects are assessed very positively by both parents and pediatricians, and therefore Magne B6 is often prescribed to children who do not have magnesium deficiency, but adults want to make them calmer and less excitable. Despite useful action Magne B6, it is not recommended to use the drug without a doctor’s prescription and supervision, especially for children 1 – 6 years old. Magne B6 is available in two dosage forms - tablets and oral solution. Tablets can only be given to children over 6 years old, provided that their body weight has reached 20 kg or more.
The dosage of Magne B6 for children is determined by their age and body weight:
- Children aged 1 – 6 years with a body weight of 10 – 20 kg– take 1 – 4 ampoules per day, having previously calculated the exact dosage based on body weight, based on the ratio of 10 – 30 mg of magnesium per 1 kg of weight per day;
- Children aged 6 – 12 years, weighing more than 20 kg– take 1 – 3 ampoules per day (1/3 – 1 ampoule 3 times a day) or 4 – 6 tablets per day (2 tablets 2 – 3 times a day);
- Teenagers over 12 years old– take 2 – 4 ampoules per day (1 ampoule 2-3 times a day or 2 ampoules 2 times a day) or 6 – 8 tablets per day (2 tablets 3 times a day or 4 tablets 2 times a day).
For children 1–6 years old, it is recommended to calculate the dosage individually based on body weight. For example, a child’s weight is 15 kg, which means he can be given a solution in a dosage of 10 * 15 = 150 mg, or 30 * 15 = 450 mg per day (calculation is based on the amount of magnesium). Since one full ampoule contains 100 mg of magnesium, 150 mg and 450 mg correspond to 1.5 or 4.5 ampoules. When the calculation results in an incomplete number of ampoules, it is rounded to whole numbers. That is, in our example, 1.5 ampoules are rounded to 2, and 4.5 - to 4, since the maximum permissible dosage for a child 1 – 6 years old is 4 ampoules.
Magne B6 forte can be given to children over 6 years old, provided that their body weight is more than 20 kg. The dosage of Magne B6 forte for children of different ages is as follows:
- Teenagers over 12 years old– take 3 – 4 tablets per day (1 tablet 3 times a day or 2 tablets 2 times a day);
- Children 6 – 12 years old– take 2 – 4 tablets per day (1 tablet 2-3 times a day or 2 tablets 2 times a day).
The course of use of Magne B6 for children without confirmed magnesium deficiency is 2–3 weeks. For children with identified and laboratory confirmed magnesium deficiency, the drug is given until the level of the mineral in the blood rises to normal values.
Analogs
Magne B6 has two types of analogues - these are synonyms and, in fact, analogues. Synonyms include medicines, which contain the same active substances as Magne B6. Analogues include drugs that have a similar spectrum of therapeutic action, but contain other active substances.On the Russian pharmaceutical market Magne B6 has only three synonymous drugs:
- Magnelis B6;
- Magwit;
- Magnesium plus B6.
The following drugs are analogues of Magne B6:
- Additiva magnesium effervescent tablets;
- Vitrum Mag chewable tablets;
- Magne Positive tablets;
- Magne Express granules for resorption;
- Magnerot tablets;
- Magnesium-Diasporal 300 granules for the preparation of solution for oral administration;
- Magnesium plus tablets.
Cheap analogues of Magne B6
The following drugs are cheaper synonyms compared to Magne B6:- Magnelis B6 – 250 – 370 rubles for 90 tablets;
- Magnesium plus B6 – 320 – 400 rubles for 50 tablets.
The only cheaper analogue of Magne B6 is Vitrum Mag - 270 - 330 rubles for 30 tablets.
Compound Active ingredients:
- magnesium lactate dihydrate* - 186 mg;
- magnesium pidolate* - 936 mg;
- pyridoxine hydrochloride - 10 mg;
Excipients:
- sodium disulfite - 15 mg,
- sodium saccharinate - 15 mg,
- cherry-caramel flavoring - 0.3 ml,
- purified water up to 10 ml.
* - equivalent to a total magnesium content (Mg++) of 100 mg.
Description Clear liquid brown with the smell of caramel.Pharmacological properties
Pharmacodynamics
Magnesium is vital important element, which is found in all tissues of the body and is necessary for normal functioning cells, participates in most metabolic reactions. In particular, it is involved in the regulation of the transmission of nerve impulses and muscle contraction. The body receives magnesium through food. A lack of magnesium in the body can occur when the diet is disrupted or when the need for magnesium increases (with increased physical and mental stress, stress, pregnancy, use of diuretics).
Pyridoxine (vitamin B6) is involved in many metabolic processes, in the regulation of nervous system metabolism. Vitamin B6 improves the absorption of magnesium from gastrointestinal tract and its penetration into cells.
Serum magnesium levels:- from 12 to 17 mg/l (0.5 – 0.7 mmol/l) - moderate magnesium deficiency;
- below 12 mg/l (0.5 mmol/l) - severe magnesium deficiency.
Absorption of magnesium in the gastrointestinal tract is no more than 50% of the dose taken orally. 99% of magnesium in the body is found inside cells. Approximately 2/3 of intracellular magnesium is distributed in bone tissue, 1/3 is in smooth and striated muscle tissue. Magnesium is excreted primarily in the urine (at least 1/3 of dose taken magnesium).
Indications for use
Indications for use
Established magnesium deficiency, isolated or associated with other deficiency conditions, accompanied by symptoms such as:
- increased irritability,
- minor sleep disorders,
- gastrointestinal spasms,
- rapid heartbeat,
- increased fatigue,
- pain and muscle spasms,
- tingling sensation in the muscles.
Contraindications
Contraindications
- Hypersensitivity to the components of the drug.
- Severe renal failure (creatinine clearance less than 30 ml/minute).
- Childhood up to 1 year.
- Concomitant use of levodopa (see section “Interaction with other drugs”).
With caution
- At moderate degree renal failure, as there is a risk of developing hypermagnesemia.
Use during pregnancy and lactation
Pregnancy
Breastfeeding period
Magnesium penetrates into breast milk. The use of the drug should be avoided during lactation and breastfeeding.
Directions for use and doses
Directions for use and doses
Before taking the drug, you should consult your doctor.
The drug can be used for children from 1 year of age.
For children over 1 year of age (body weight more than 10 kg), the daily dose is 10-30 mg magnesium/kg body weight (0.4 - 1.2 mmol magnesium/kg) or 1-4 ampoules.
Daily dose should be divided into 2-3 doses, taken with meals.
The solution from the ampoules is dissolved in ½ glass of water before use.
Treatment should be stopped immediately after normalization of magnesium concentration in the blood.
ATTENTION
Magne B6 ® ampoules do not require the use of a nail file. To open the ampoule, take it by the tip, having previously covered it with a piece of cloth, and break it off with a sharp movement, first from one pointed end, and then from the other, having previously directed open first the end of the ampoule at an angle into a glass of water, so that the tip of the ampoule that is broken off by the second is not above the glass. After breaking off the second tip of the ampoule, its contents will flow freely into the glass.
Side effect
Side effect
According to World Organization health (WHO) unwanted effects classified according to their frequency of development as follows: very often (≥ 1/10), often (≥1/100,
Violations by immune system:
Very rare: allergic reactions. Frequency unknown: skin reactions(urticaria, itching), severe allergic reactions, including bronchospasm
Gastrointestinal disorders:
Frequency unknown: diarrhea, abdominal pain.
Overdose
Overdose
Symptoms
At normal function kidneys, an overdose of magnesium when taken orally usually does not lead to toxic reactions. However, in case of renal failure, magnesium poisoning may develop.
Symptoms of overdose, the severity of which depends on the concentration of magnesium in the blood: decrease blood pressure; nausea, vomiting; depression of the central nervous system, decreased reflexes; changes in the electrocardiogram; respiratory depression, coma, cardiac arrest and respiratory paralysis; anuric syndrome.
Treatment
Rehydration, forced diuresis. In case of renal failure, hemodialysis or peritoneal dialysis is necessary.
Interaction with other drugs
Interaction with other drugs
Contraindicated combinations
- With levodopa: the activity of levodopa is inhibited by pyridoxine (unless this drug is combined with the use of peripheral aromatic L-amino acid decarboxylase inhibitors). Any amount of pyridoxine should be avoided unless levodopa is taken in combination with peripheral aromatic L-amino acid decarboxylase inhibitors.
- The simultaneous use of drugs containing phosphates or calcium salts may impair the absorption of magnesium in the intestine.
Combinations to Consider
- When prescribing tetracyclines orally, it is necessary to maintain an interval of at least three hours between ingestion of tetracycline and Magne B6, since magnesium preparations reduce the absorption of tetracyclines.
Special instructions
Special instructions
In case of severe magnesium deficiency or malabsorption syndrome, treatment begins with intravenous administration magnesium preparations.
In case of concomitant calcium deficiency, it is recommended to correct the magnesium deficiency before taking calcium supplements or food additives containing calcium.
With frequent use of laxatives, alcohol, strenuous physical and mental stress the need for magnesium increases, which can lead to the development of magnesium deficiency in the body.
The oral solution contains sulfite, which may cause or worsen symptoms. allergic reactions, including anaphylactic reactions, especially in patients at risk.
When using pyridoxine in high doses (more than 200 mg per day) for a long time (over several months or in some cases years), sensory axonal neuropathy may develop, which is accompanied by symptoms such as numbness, impaired proprioceptive sensitivity, distal tremor limbs and gradually developing sensory ataxia (impaired coordination of movements). These disorders are usually reversible and disappear after stopping taking vitamin B6.
Magnesium - essential trace element, responsible for the health of the heart, liver, kidneys, as well as bones and muscles. It regulates the functioning of the nervous system, supports normal level cholesterol, takes part in protein synthesis, regulation of cell growth, phosphorus metabolism. Thanks to it, the heart muscle works properly, and the risk of developing cardiovascular diseases becomes significantly lower. Magnesium is prescribed to children and adults, expectant mothers, people over 50 years old, pensioners - each of us needs it, and its deficiency can lead to unpleasant symptoms: problems with sleep, increased fatigue, regular cramps, etc. What are the causes of magnesium deficiency and when is it necessary to use Magne B6?
Causes of magnesium deficiency
There are two types of magnesium deficiency - primary and secondary. In the first case we're talking about O genetic diseases, which provoked a lack of magnesium in the body. This is very rare case, so let’s focus on the second type - secondary deficit. It is much more common and is caused by:
- lack of magnesium in the food a person eats;
- abuse harmful products: semi-finished products, sugar, alcoholic drinks, caffeinated products, etc.;
- poor environment;
- stress, increased physical activity;
- taking diuretics;
- taking immunosuppressants;
- taking inhibitors proton pump;
- reception contraceptive drugs With high doses hormones;
- chronic diseases different body systems.
Symptoms of magnesium deficiency
If you have one or more of the following symptoms, your body may not have enough magnesium:
- increased nervous excitability, irritability, anxiety;
- tingling in the limbs;
- spasms or cramps;
- rapid heartbeat;
- increased fatigue;
- sleep disorders.
All this may indicate a magnesium deficiency, but it is better not to diagnose it yourself, but to consult a doctor. The Magne B6 medicine itself is safe, but it should not be used, for example, when taking laxatives or when breastfeeding. Read more about this in the section “Contraindications to taking magnesium.”
Diseases for which magnesium supplementation is indicated
Magnesium intake is indicated for the following diseases and conditions:
- high blood pressure;
- heart failure;
- violations heart rate;
- atherosclerosis;
- elevated level cholesterol;
- coronary disease hearts;
- tendency to thrombosis;
- vegetative-vascular dystonia;
- depression;
- insomnia;
- increased nervous excitability;
- migraines;
- chronic obstructive pulmonary disease.
Magnesium with vitamin B6 is also prescribed for asthma, constipation, osteoporosis, premenstrual syndrome and more. Being a regulator of processes occurring in the body, Magne B6 and its analogues can be used in the most different cases- indications for use are very extensive.
How to drink Magne B6 for adults?
Usually, when it comes to adult patients, the doctor prescribes 2-4 ampoules or 6-8 tablets of magnesium with B6 per day. The medicine should be taken with meals, with a glass ordinary water. Children over 12 years of age are usually prescribed adult doses of drugs containing this trace element. Pregnant women need more magnesium, which is reflected in their schedule for taking Magne B6. In any case, the decision is made by the doctor, not the patient.
Many foods are natural sources of magnesium:
- nuts: roasted almonds, cashews, peanuts;
- legumes: boiled or stewed lentils/beans;
- cereals: cooked brown/ white rice, oatmeal instant cooking;
- fruits: avocados, bananas, which are known to everyone;
- vegetables: jacket potatoes, carrots and especially which are very rich;
- meat and fish: lean beef, chicken breast, halibut, salmon;
- whole grain bread;
- regular and soy milk;
- low-fat yogurt (no fruit);
- raisin.
Magne B6 and its analogues
Magnesium with vitamin B6 is available in the form of a solution (10 ampoules per package) or in tablets (N30 or N50). Below is information about the content of magnesium and B6 in ampoules and tablets. Read and decide which form is more convenient for you, and then tell your doctor.
Composition of Magne B6 (tablets): magnesium lactate dihydrate - 470 mg (48 mg of pure magnesium); vitamin B6 (pyridoxine hydrochloride) - 5 mg.
Composition of Magne B6 (solution in ampoules for oral administration): magnesium lactate dihydrate - 186 mg and magnesium pidolate - 936 mg (a total of 100 mg of pure magnesium); vitamin B6 (pyridoxine hydrochloride) - 10 mg.
Composition of Magne B6 forte: magnesium citrate - 618.43 mg (100 mg of pure magnesium); vitamin B6 (pyridoxine hydrochloride) - 10 mg.
Thus, greatest number Pure magnesium is contained in Magne B6 solution and Magne B6 forte. They also contain a higher content of vitamin B6 compared to the usual Magne B6 tablets.
The effect of taking magnesium with vitamin B6 is not noticeable immediately, but only after 2-3 weeks. The drug has a cumulative effect, which means that nothing in your body will change after a couple of days of taking it. Usually it is drunk for 1 month.
Taking Magne B6 as a course is quite expensive - the drug is actively advertised, and its prices in many pharmacies significantly hit the wallet. It’s good if you managed to find a pharmacy with a good price for this drug. If not, don’t worry, Magne B6 has analogues, for example:
- Magnelis B6;
- Beresh plus;
- Magnefar;
- Magwit B6.
Preparations containing magnesium and vitamin B6 are produced by various global pharmaceutical companies: Evalar, Arkopharma, Renewal, etc. These medications themselves are no different from each other. The main thing you should pay attention to is the amount of magnesium in the preparation. The dosage and effectiveness of taking the medicine depends on this.
Contraindications to taking magnesium
The drug Magne B6 and its analogues are contraindicated in:
- kidney diseases (especially for patients with renal failure);
- breastfeeding;
- alcohol abuse;
- taking laxatives;
- hypersensitivity to the components of the drug;
- diabetes (if sucrose is present among the excipients of magnesium tablets).
Also, magnesium in ampoules should not be taken by children under 1 year of age, and in tablets by children under 6 years of age.
This is not full list Contraindications - You should consult your doctor before taking this drug. The instructions for use are also important - they contain comprehensive information about this medicine. You can easily find it on the Internet.
Side effects
When taking Magne B6 (solution, tablets, Magne B6 forte), the following side effects may be observed:
- allergic reactions;
- numbness of the limbs;
- nausea, vomiting;
- flatulence;
- diarrhea, constipation;
- pain in the abdomen;
- crawling sensation;
- peripheral neuropathy (tingling in the feet, palms).
But, as a rule, taking magnesium is comfortable, and side effects are observed very rarely.
The role of magnesium in the body cannot be underestimated. Due to the lack of this substance, many pathological conditions can develop that will require serious treatment. Many experts agree that magnesium is one of the most important chemical elements in the human body, ranking second after oxygen. Therefore, drugs with this substance are prescribed not only for prevention, but also in complex treatment many diseases.
In this article we'll talk such a drug as “Magnesium B6”. It is used quite often for children. Which form of release is best to give preference to, how to take it, whether this medication has side effects and contraindications - these numerous questions arise as soon as it becomes necessary to give this medicine to a child.
It should be noted here that it is impossible to use the drug “Magnesium B6” for children without a doctor’s prescription. Self-medication can lead to an overabundance of this substance in the body and to other problems associated with this condition. Therefore, if there is a suspicion that the child’s body lacks exactly this chemical element, then you should not go to the pharmacy, but to an appointment with a pediatrician, who will conduct an examination, prescribe tests and make appointments.
General description
The drug "Magnesium B6" (for children it is used no less often than for adults) can be classified as vitamin preparations. Therefore, it is prescribed not only for treatment, but also for the prevention of deficiency of this chemical element in tissues and organs. The combination of magnesium and is not just a whim of pharmacists. It’s just that when these two substances are taken simultaneously, the medicine becomes more effective:
- the body's overall resistance to infections increases;
- improves absorption and assimilation of magnesium;
- vascular tone is normalized;
- has a calming effect on the nervous system, promotes good sleep and reducing overall stress.
The main indications for taking the drug “Magnesium B6” for children are various neuroses and a lack of magnesium, proven by laboratory tests.
For ease of use pharmaceutical companies developed various shapes release of this medicine, which allows you to choose the most appropriate option depending on the age of the baby and his condition.
The course of therapy usually lasts a month, but the doctor may change this time or divide it into intermittent sessions.
The drug is in the form of a solution
Liquid Magnesium B6 for children is available in ampoules that are easy to open without a special nail file. As a rule, it is prescribed to children starting from one year old, provided that the child’s body weight has already reached 10 kg. The calculation is based on the recommended dose: 10-30 mg of the drug per kilogram of weight, depending on the severity of the condition and well-being little patient. To take the medicine “Magnesium B6”, ampoules (this form of the drug is very convenient to use for children) are opened by lightly pressing the tip of the glass, wrapped in a napkin, and the contents are dissolved in a glass of water, which the child should drink throughout the day. It is advisable not to reduce this volume of liquid.
Quite often, ampoules are mistakenly called “Magnesium B6, syrup for children,” although there is no significant difference here, because after dilution, a sweetish solution with a pleasant aftertaste is obtained, which is usually liked by children. The drug is prescribed intravenously and intramuscularly in extreme cases when the patient's condition reaches critical.
The drug is in the form of a gel
One more convenient form release of the drug "Magnesium B6" - gel. It is also convenient to use for children. As a rule, all kids happily take this sweet medicine. The dosage in most cases is selected individually by the pediatrician. The recommended treatment regimen for this form of medication is as follows:
- for children from three to five years old, 5 g of medicine (one measuring spoon) once a day;
- from 5 to 12 years - 10 g of gel, divided into two doses;
- adolescents are recommended 5 g three times a day.
Drug in tablets
The tablet form of the drug can be taken by children from the age of six, since, firstly, the tablets contain a different dosage, designed for patients weighing more than 20 kg, and secondly, children will not be able to swallow the tablet. The treatment regimen, as a rule, is established individually after a thorough examination of the patient. The dosage can be from 4 to 6 tablets per day, depending on the age of the child and his well-being.
What do the instructions say about the rules for taking the medication “Magnesium B6”? It is very important for children to take the medicine correctly to get the full benefit from the treatment. But you should not neglect the rules, since tests have shown that only under such conditions of administration is the maximum concentration of active substances in the body achieved. Therefore, you need to swallow the medicine in this form of release whole, without chewing in any case, and wash it down not with several sips, as is customary for many patients, but with a glass of water. The tablets should be taken with meals.
Contraindications
Drinking the drug “Magnesium B6” (the solution for children is most preferable) without a doctor’s prescription is dangerous not only because of the possible excess active substance in the body, but also because this medicine contraindicated in a number of cases related to certain diseases and features. So, for example, taking it will be dangerous if the following conditions are observed:
- impaired absorption of glucose and galactose;
- sucrase-isomaltase deficiency;
- severe renal failure with CK indicator< 30 мл/мин;
- individual intolerance to the components included in the composition.
It should be noted here that it is strictly forbidden to use the medicine, ignoring age restrictions.
Side effects from taking
Any intervention in the body using chemicals, which are medicines, may have certain negative impacts on the body. The drug "Magnesium B6" is no exception. The following symptoms may occur while taking this medication:
- constipation;
- nausea and abdominal pain;
- flatulence;
- skin rashes.
At similar manifestations you should postpone taking the medicine and consult your doctor for advice regarding further actions and course of treatment.
